|
| infusions_d1_control number of infusions earned (intravenous self administration), saline
, day 1
111414
|
(F) |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
2 |
1 |
|
3 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
|
2 |
3 |
|
2 |
1 |
1 |
2 |
2 |
1 |
1 |
1 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
2 |
3 |
3 |
3 |
4 |
3 |
2 |
2 |
|
2 |
3 |
1 |
1 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
|
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
4 |
1 |
2 |
3 |
2 |
3 |
3 |
2 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| infusions_d2_control number of infusions earned (intravenous self administration), saline
, day 2
111415
|
(F) |
1 |
1 |
2 |
2 |
3 |
3 |
3 |
|
1 |
1 |
1 |
2 |
|
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
1 |
2 |
2 |
|
3 |
|
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
4 |
1 |
2 |
3 |
2 |
2 |
3 |
|
2 |
3 |
1 |
2 |
1 |
2 |
2 |
2 |
1 |
2 |
|
3 |
|
3 |
| (M) |
1 |
|
3 |
3 |
3 |
4 |
3 |
2 |
2 |
1 |
1 |
3 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
1 |
3 |
3 |
3 |
|
2 |
1 |
1 |
3 |
2 |
2 |
2 |
1 |
1 |
|
1 |
2 |
1 |
3 |
2 |
1 |
3 |
1 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
2 |
2 |
|
3 |
|
| infusions_d3_control number of infusions earned (intravenous self administration), saline
, day 3
111416
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
3 |
2 |
2 |
1 |
2 |
2 |
1 |
1 |
|
3 |
1 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
3 |
3 |
3 |
|
3 |
3 |
2 |
2 |
3 |
2 |
2 |
3 |
2 |
2 |
1 |
2 |
|
2 |
2 |
3 |
1 |
3 |
1 |
3 |
| (M) |
|
|
3 |
3 |
3 |
4 |
2 |
2 |
2 |
1 |
2 |
2 |
1 |
2 |
|
3 |
3 |
1 |
3 |
|
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
1 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
2 |
2 |
1 |
2 |
1 |
3 |
|
| infusions_d4_control number of infusions earned (intravenous self administration), saline
, day 4
111417
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
|
1 |
1 |
1 |
2 |
|
|
2 |
3 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
4 |
1 |
2 |
3 |
2 |
2 |
3 |
2 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
3 |
2 |
2 |
3 |
3 |
1 |
2 |
| (M) |
1 |
|
3 |
2 |
3 |
4 |
2 |
2 |
2 |
|
2 |
2 |
1 |
1 |
1 |
2 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
|
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
4 |
2 |
1 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
2 |
2 |
1 |
3 |
|
| infusions_d5_control number of infusions earned (intravenous self administration), saline
, day 5
111418
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
|
|
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
1 |
3 |
2 |
3 |
3 |
1 |
2 |
2 |
2 |
3 |
2 |
2 |
|
3 |
2 |
1 |
2 |
3 |
1 |
3 |
| (M) |
|
|
3 |
1 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
1 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
|
1 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
2 |
3 |
|
| infusions_d6_control number of infusions earned (intravenous self administration), saline
, day 6
111419
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
|
1 |
2 |
1 |
|
|
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
3 |
3 |
|
3 |
|
2 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
1 |
1 |
2 |
3 |
2 |
2 |
|
3 |
|
3 |
| (M) |
1 |
1 |
3 |
3 |
3 |
4 |
2 |
|
2 |
|
3 |
4 |
1 |
1 |
2 |
3 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
|
2 |
3 |
3 |
3 |
|
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
2 |
1 |
3 |
|
| infusions_d7_control number of infusions earned (intravenous self administration), saline
, day 7
111420
|
(F) |
|
|
2 |
2 |
3 |
3 |
2 |
|
1 |
2 |
1 |
3 |
|
|
2 |
3 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
|
2 |
2 |
3 |
1 |
3 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
|
3 |
2 |
3 |
2 |
2 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
|
3 |
| (M) |
1 |
|
3 |
1 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
2 |
3 |
|
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
2 |
1 |
3 |
2 |
2 |
3 |
1 |
2 |
|
3 |
|
| infusions_d8_control number of infusions earned (intravenous self administration), saline
, day 8
111421
|
(F) |
|
1 |
2 |
2 |
3 |
3 |
3 |
|
1 |
2 |
1 |
2 |
|
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
|
2 |
2 |
2 |
1 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
1 |
3 |
| (M) |
|
1 |
2 |
2 |
3 |
4 |
2 |
|
2 |
|
3 |
3 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
|
2 |
1 |
3 |
|
| infusions_d9_control number of infusions earned (intravenous self administration), saline
, day 9
111422
|
(F) |
|
|
3 |
2 |
3 |
3 |
2 |
|
1 |
2 |
1 |
1 |
1 |
1 |
3 |
3 |
1 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
1 |
2 |
2 |
2 |
3 |
2 |
3 |
|
3 |
| (M) |
|
|
2 |
2 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
3 |
2 |
2 |
2 |
3 |
2 |
2 |
2 |
2 |
1 |
2 |
1 |
2 |
2 |
3 |
|
| infusions_d10_control number of infusions earned (intravenous self administration), saline
, day 10
111423
|
(F) |
|
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
1 |
|
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
2 |
3 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
2 |
2 |
3 |
2 |
3 |
|
3 |
| (M) |
1 |
|
3 |
2 |
3 |
4 |
2 |
2 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
2 |
2 |
2 |
2 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
1 |
2 |
2 |
3 |
|
| infusions_d1_cocaine number of infusions earned (intravenous self administration), cocaine
, day 1
111424
|
(F) |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
1 |
1 |
2 |
3 |
2 |
2 |
2 |
3 |
1 |
2 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
1 |
4 |
4 |
| (M) |
2 |
1 |
2 |
3 |
3 |
4 |
3 |
1 |
1 |
1 |
1 |
3 |
1 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
|
3 |
3 |
1 |
2 |
2 |
|
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
2 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| infusions_d2_cocaine number of infusions earned (intravenous self administration), cocaine
, day 2
111425
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
2 |
2 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
1 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
1 |
|
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
3 |
1 |
3 |
2 |
3 |
2 |
1 |
|
4 |
| (M) |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
2 |
2 |
3 |
1 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
1 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
1 |
4 |
|
| infusions_d3_cocaine number of infusions earned (intravenous self administration), cocaine
, day 3
111426
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
2 |
2 |
2 |
2 |
1 |
2 |
2 |
2 |
1 |
2 |
|
1 |
2 |
1 |
|
3 |
|
1 |
|
1 |
2 |
1 |
2 |
3 |
|
3 |
1 |
1 |
1 |
3 |
1 |
3 |
3 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
2 |
2 |
1 |
4 |
| (M) |
2 |
|
2 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
4 |
|
| infusions_d4_cocaine number of infusions earned (intravenous self administration), cocaine
, day 4
111427
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
3 |
1 |
2 |
2 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
|
3 |
|
2 |
|
1 |
2 |
1 |
2 |
3 |
|
2 |
|
2 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
2 |
1 |
3 |
2 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
2 |
1 |
2 |
4 |
| (M) |
2 |
|
2 |
2 |
3 |
3 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
4 |
|
| infusions_d5_cocaine number of infusions earned (intravenous self administration), cocaine
, day 5
111428
|
(F) |
|
1 |
3 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
|
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
2 |
3 |
3 |
1 |
2 |
3 |
1 |
3 |
2 |
3 |
1 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
3 |
2 |
2 |
1 |
4 |
| (M) |
2 |
|
2 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
1 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
3 |
1 |
|
1 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
4 |
|
| infusions_d6_cocaine number of infusions earned (intravenous self administration), cocaine
, day 6
111429
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
1 |
1 |
|
3 |
3 |
1 |
2 |
3 |
|
1 |
2 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
|
2 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
2 |
4 |
|
| infusions_d7_cocaine number of infusions earned (intravenous self administration), cocaine
, day 7
111430
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
2 |
2 |
|
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
3 |
2 |
1 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
2 |
2 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| infusions_d8_cocaine number of infusions earned (intravenous self administration), cocaine
, day 8
111431
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
3 |
1 |
|
2 |
2 |
1 |
2 |
|
1 |
3 |
2 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
1 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
|
1 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
2 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
|
4 |
|
| infusions_d9_cocaine number of infusions earned (intravenous self administration), cocaine
, day 9
111432
|
(F) |
1 |
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
3 |
2 |
2 |
3 |
1 |
|
2 |
2 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
2 |
3 |
2 |
3 |
1 |
3 |
2 |
2 |
2 |
4 |
| (M) |
2 |
|
1 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
2 |
|
2 |
2 |
1 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
|
2 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
4 |
|
| infusions_d10_cocaine number of infusions earned (intravenous self administration), cocaine
, day 10
111433
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
1 |
3 |
|
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
4 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
|
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| infusions_d1_4_control number of infusions earned (intravenous self administration) combined, saline
, days 1-4
111434
|
(F) |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
2 |
3 |
3 |
3 |
4 |
3 |
2 |
2 |
1 |
2 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| infusions_d5_7_control number of infusions earned (intravenous self administration) combined, saline
, days 5-7
111435
|
(F) |
|
|
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
3 |
|
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
2 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
| (M) |
2 |
1 |
3 |
3 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
|
| infusions_d8_10_control number of infusions earned (intravenous self administration) combined, saline
, days 8-10
111436
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
| (M) |
1 |
1 |
3 |
3 |
3 |
4 |
2 |
2 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
|
| infusions_d1_4_cocaine number of infusions earned (intravenous self administration), cocaine
, days 1-4
111437
|
(F) |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
4 |
4 |
| (M) |
2 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| infusions_d5_7_cocaine number of infusions earned (intravenous self administration), cocaine
, days 5-7
111438
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
|
| infusions_d8_10_cocaine number of infusions earned (intravenous self administration), cocaine
, days 8-10
111439
|
(F) |
1 |
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
4 |
| (M) |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
4 |
2 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
4 |
|
| active_pct_d1_control percentage of lever presses that are active (intravenous self administration), saline
, day 1
111440
|
(F) |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
2 |
1 |
|
3 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
|
2 |
3 |
|
2 |
1 |
1 |
2 |
2 |
1 |
1 |
1 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
2 |
3 |
3 |
3 |
4 |
3 |
2 |
2 |
|
2 |
3 |
1 |
1 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
|
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
4 |
1 |
2 |
3 |
2 |
3 |
3 |
2 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| active_pct_d2_control percentage of lever presses that are active (intravenous self administration), saline
, day 2
111441
|
(F) |
1 |
1 |
2 |
2 |
3 |
3 |
3 |
|
1 |
1 |
1 |
2 |
|
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
1 |
2 |
2 |
|
3 |
|
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
4 |
1 |
2 |
3 |
2 |
2 |
3 |
|
2 |
3 |
1 |
2 |
1 |
2 |
2 |
2 |
1 |
2 |
|
3 |
|
3 |
| (M) |
1 |
|
3 |
3 |
3 |
4 |
3 |
2 |
2 |
1 |
1 |
3 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
1 |
3 |
3 |
3 |
|
2 |
1 |
1 |
3 |
2 |
2 |
2 |
1 |
1 |
|
1 |
2 |
1 |
3 |
2 |
1 |
3 |
1 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
2 |
2 |
|
3 |
|
| active_pct_d3_control percentage of lever presses that are active (intravenous self administration), saline
, day 3
111442
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
3 |
2 |
2 |
1 |
2 |
2 |
1 |
1 |
|
3 |
1 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
3 |
3 |
3 |
|
3 |
3 |
2 |
2 |
3 |
2 |
2 |
3 |
2 |
2 |
1 |
2 |
|
2 |
2 |
3 |
1 |
3 |
1 |
3 |
| (M) |
|
|
3 |
3 |
3 |
4 |
2 |
2 |
2 |
1 |
2 |
2 |
1 |
2 |
|
3 |
3 |
1 |
3 |
|
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
1 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
2 |
2 |
1 |
2 |
1 |
3 |
|
| active_pct_d4_control percentage of lever presses that are active (intravenous self administration), saline
, day 4
111443
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
|
1 |
1 |
1 |
2 |
|
|
2 |
3 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
4 |
1 |
2 |
3 |
2 |
2 |
3 |
2 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
2 |
| (M) |
1 |
|
3 |
2 |
3 |
4 |
2 |
2 |
2 |
|
2 |
2 |
1 |
1 |
1 |
2 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
|
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
4 |
2 |
1 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
2 |
2 |
1 |
3 |
|
| active_pct_d5_control percentage of lever presses that are active (intravenous self administration), saline
, day 5
111444
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
|
|
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
1 |
3 |
2 |
3 |
3 |
1 |
2 |
2 |
2 |
3 |
2 |
2 |
|
3 |
2 |
1 |
2 |
3 |
1 |
3 |
| (M) |
|
|
3 |
1 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
1 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
|
1 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
2 |
3 |
|
| active_pct_d6_control percentage of lever presses that are active (intravenous self administration), saline
, day 6
111445
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
|
1 |
2 |
1 |
|
|
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
3 |
3 |
|
3 |
|
2 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
1 |
1 |
2 |
3 |
2 |
2 |
|
3 |
|
3 |
| (M) |
1 |
1 |
3 |
3 |
3 |
4 |
2 |
|
2 |
|
3 |
4 |
1 |
1 |
2 |
3 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
|
2 |
3 |
3 |
3 |
|
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
2 |
1 |
3 |
|
| active_pct_d7_control percentage of lever presses that are active (intravenous self administration), saline
, day 7
111446
|
(F) |
|
|
2 |
2 |
3 |
3 |
2 |
|
1 |
2 |
1 |
3 |
|
|
2 |
3 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
|
2 |
2 |
3 |
1 |
3 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
|
3 |
2 |
3 |
2 |
2 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
|
3 |
| (M) |
1 |
|
3 |
1 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
2 |
3 |
|
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
2 |
1 |
3 |
2 |
2 |
3 |
1 |
2 |
|
3 |
|
| active_pct_d8_control percentage of lever presses that are active (intravenous self administration), saline
, day 8
111447
|
(F) |
|
1 |
2 |
2 |
3 |
3 |
3 |
|
1 |
2 |
1 |
2 |
|
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
|
2 |
2 |
2 |
1 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
1 |
3 |
| (M) |
|
1 |
2 |
2 |
3 |
4 |
2 |
|
2 |
|
3 |
3 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
|
2 |
1 |
3 |
|
| active_pct_d9_control percentage of lever presses that are active (intravenous self administration), saline
, day 9
111448
|
(F) |
|
|
3 |
2 |
3 |
3 |
2 |
|
1 |
2 |
1 |
1 |
1 |
1 |
3 |
3 |
1 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
1 |
2 |
2 |
2 |
3 |
2 |
3 |
|
3 |
| (M) |
|
|
2 |
2 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
3 |
2 |
2 |
2 |
3 |
2 |
2 |
2 |
2 |
1 |
2 |
1 |
2 |
2 |
3 |
|
| active_pct_d10_control percentage of lever presses that are active (intravenous self administration), saline
, day 10
111449
|
(F) |
|
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
1 |
|
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
2 |
3 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
2 |
2 |
3 |
2 |
3 |
|
3 |
| (M) |
1 |
|
3 |
2 |
3 |
4 |
2 |
2 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
2 |
2 |
2 |
2 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
1 |
2 |
2 |
3 |
|
| active_pct_d1_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 1
111450
|
(F) |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
1 |
1 |
2 |
3 |
2 |
2 |
2 |
3 |
1 |
2 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
1 |
4 |
4 |
| (M) |
2 |
1 |
2 |
3 |
3 |
4 |
3 |
1 |
1 |
1 |
1 |
3 |
1 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
|
3 |
3 |
1 |
2 |
2 |
|
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
2 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| active_pct_d2_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 2
111451
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
2 |
2 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
1 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
1 |
|
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
3 |
1 |
3 |
2 |
3 |
2 |
1 |
|
4 |
| (M) |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
2 |
2 |
3 |
1 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
1 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
1 |
4 |
|
| active_pct_d3_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 3
111452
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
2 |
2 |
2 |
2 |
1 |
2 |
2 |
2 |
1 |
2 |
|
1 |
2 |
1 |
|
3 |
|
1 |
|
1 |
2 |
1 |
2 |
3 |
|
3 |
1 |
1 |
1 |
3 |
1 |
3 |
3 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
2 |
2 |
1 |
4 |
| (M) |
2 |
|
2 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
4 |
|
| active_pct_d4_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 4
111453
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
3 |
1 |
2 |
2 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
|
3 |
|
2 |
|
1 |
2 |
1 |
2 |
3 |
|
2 |
|
2 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
2 |
1 |
3 |
2 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
2 |
1 |
3 |
4 |
| (M) |
2 |
|
2 |
2 |
3 |
3 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
4 |
|
| active_pct_d5_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 5
111454
|
(F) |
|
1 |
3 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
|
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
2 |
3 |
3 |
1 |
2 |
3 |
1 |
3 |
2 |
3 |
1 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
3 |
2 |
2 |
1 |
4 |
| (M) |
2 |
|
2 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
1 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
3 |
1 |
|
1 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
4 |
|
| active_pct_d6_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 6
111455
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
1 |
1 |
|
3 |
3 |
1 |
2 |
3 |
|
1 |
2 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
|
2 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
2 |
4 |
|
| active_pct_d7_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 7
111456
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
2 |
2 |
|
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
3 |
2 |
1 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
2 |
2 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| active_pct_d8_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 8
111457
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
3 |
1 |
|
2 |
2 |
1 |
2 |
|
1 |
3 |
2 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
1 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
|
1 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
2 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
|
4 |
|
| active_pct_d9_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 9
111458
|
(F) |
1 |
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
3 |
2 |
2 |
3 |
1 |
|
2 |
2 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
2 |
3 |
2 |
3 |
1 |
3 |
2 |
2 |
2 |
4 |
| (M) |
2 |
|
1 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
2 |
|
2 |
2 |
1 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
|
2 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
4 |
|
| active_pct_d10_cocaine percentage of lever presses that are active (intravenous self administration), cocaine
, day 10
111459
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
1 |
3 |
|
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
4 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
|
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| active_pct_d1_4_control percentage of lever presses that are active (intravenous self administration) combined, saline
, days 1-4
111460
|
(F) |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
2 |
3 |
3 |
3 |
4 |
3 |
2 |
2 |
1 |
2 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| active_pct_d5_7_control percentage of lever presses that are active (intravenous self administration) combined, saline
, days 5-7
111461
|
(F) |
|
|
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
3 |
|
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
2 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
| (M) |
2 |
1 |
3 |
3 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
|
| active_pct_d8_10_control percentage of lever presses that are active (intravenous self administration) combined, saline
, days 8-10
111462
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
| (M) |
1 |
1 |
3 |
3 |
3 |
4 |
2 |
2 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
|
| active_pct_d1_4_cocaine percentage of lever presses that are active (intravenous self administration) combined, cocaine
, days 1-4
111463
|
(F) |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
4 |
4 |
| (M) |
2 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| active_pct_d5_7_cocaine percentage of lever presses that are active (intravenous self administration) combined, cocaine
, days 5-7
111464
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
|
| active_pct_d8_10_cocaine percentage of lever presses that are active (intravenous self administration) combined, cocaine
, days 8-10
111465
|
(F) |
1 |
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
4 |
| (M) |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
4 |
2 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
4 |
|
| active_d1_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 1
111466
|
(F) |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
2 |
1 |
|
3 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
|
2 |
3 |
|
2 |
1 |
1 |
2 |
2 |
1 |
1 |
1 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
2 |
3 |
3 |
3 |
4 |
3 |
2 |
2 |
|
2 |
3 |
1 |
1 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
|
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
4 |
1 |
2 |
3 |
2 |
3 |
3 |
2 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| active_d2_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 2
111467
|
(F) |
1 |
1 |
2 |
2 |
3 |
3 |
3 |
|
1 |
1 |
1 |
2 |
|
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
1 |
2 |
2 |
|
3 |
|
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
4 |
1 |
2 |
3 |
2 |
2 |
3 |
|
2 |
3 |
1 |
2 |
1 |
2 |
2 |
2 |
1 |
2 |
|
3 |
|
3 |
| (M) |
1 |
|
3 |
3 |
3 |
4 |
3 |
2 |
2 |
1 |
1 |
3 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
1 |
3 |
3 |
3 |
|
2 |
1 |
1 |
3 |
2 |
2 |
2 |
1 |
1 |
|
1 |
2 |
1 |
3 |
2 |
1 |
3 |
1 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
2 |
2 |
|
3 |
|
| active_d3_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 3
111468
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
3 |
2 |
2 |
1 |
2 |
2 |
1 |
1 |
|
3 |
1 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
3 |
3 |
3 |
|
3 |
3 |
2 |
2 |
3 |
2 |
2 |
3 |
2 |
2 |
1 |
2 |
|
2 |
2 |
3 |
1 |
3 |
1 |
3 |
| (M) |
|
|
3 |
3 |
3 |
4 |
2 |
2 |
2 |
1 |
2 |
2 |
1 |
2 |
|
3 |
3 |
1 |
3 |
|
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
1 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
2 |
2 |
1 |
2 |
1 |
3 |
|
| active_d4_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 4
111469
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
|
1 |
1 |
1 |
2 |
|
|
2 |
3 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
4 |
1 |
2 |
3 |
2 |
2 |
3 |
2 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
2 |
| (M) |
1 |
|
3 |
2 |
3 |
4 |
2 |
2 |
2 |
|
2 |
2 |
1 |
1 |
1 |
2 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
|
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
|
3 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
4 |
2 |
1 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
2 |
2 |
1 |
3 |
|
| active_d5_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 5
111470
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
|
|
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
1 |
3 |
2 |
3 |
3 |
1 |
2 |
2 |
2 |
3 |
2 |
2 |
|
3 |
2 |
1 |
2 |
3 |
1 |
3 |
| (M) |
|
|
3 |
1 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
1 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
|
1 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
2 |
3 |
|
| active_d6_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 6
111471
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
|
1 |
2 |
1 |
|
|
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
3 |
3 |
|
3 |
|
2 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
1 |
1 |
2 |
3 |
2 |
2 |
|
3 |
|
3 |
| (M) |
1 |
1 |
3 |
3 |
3 |
4 |
2 |
|
2 |
|
3 |
4 |
1 |
1 |
2 |
3 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
|
2 |
3 |
3 |
3 |
|
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
2 |
1 |
3 |
|
| active_d7_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 7
111472
|
(F) |
|
|
2 |
2 |
3 |
3 |
2 |
|
1 |
2 |
1 |
3 |
|
|
2 |
3 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
|
2 |
2 |
3 |
1 |
3 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
|
3 |
2 |
3 |
2 |
2 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
|
3 |
| (M) |
1 |
|
3 |
1 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
2 |
3 |
|
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
2 |
1 |
3 |
2 |
2 |
3 |
1 |
2 |
|
3 |
|
| active_d8_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 8
111473
|
(F) |
|
1 |
2 |
2 |
3 |
3 |
3 |
|
1 |
2 |
1 |
2 |
|
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
|
2 |
2 |
2 |
1 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
1 |
3 |
| (M) |
|
1 |
2 |
2 |
3 |
4 |
2 |
|
2 |
|
3 |
3 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
|
2 |
1 |
3 |
|
| active_d9_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 9
111474
|
(F) |
|
|
3 |
2 |
3 |
3 |
2 |
|
1 |
2 |
1 |
1 |
1 |
1 |
3 |
3 |
1 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
1 |
2 |
2 |
2 |
3 |
2 |
3 |
|
3 |
| (M) |
|
|
2 |
2 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
3 |
2 |
2 |
2 |
3 |
2 |
2 |
2 |
2 |
1 |
2 |
1 |
2 |
2 |
3 |
|
| active_d10_control number of active lever presses (during infusions and timeouts) (intravenous self administration), saline
, day 10
111475
|
(F) |
|
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
2 |
2 |
1 |
|
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
2 |
3 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
2 |
2 |
3 |
2 |
3 |
|
3 |
| (M) |
1 |
|
3 |
2 |
3 |
4 |
2 |
2 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
2 |
2 |
2 |
2 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
1 |
2 |
2 |
3 |
|
| active_d1_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 1
111476
|
(F) |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
1 |
1 |
2 |
3 |
2 |
2 |
2 |
3 |
1 |
2 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
1 |
4 |
4 |
| (M) |
2 |
1 |
2 |
3 |
3 |
4 |
3 |
1 |
1 |
1 |
1 |
3 |
1 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
|
3 |
3 |
1 |
2 |
2 |
|
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
2 |
4 |
2 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| active_d2_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 2
111477
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
2 |
2 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
1 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
1 |
|
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
3 |
1 |
3 |
2 |
3 |
2 |
1 |
|
4 |
| (M) |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
2 |
2 |
3 |
1 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
1 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
1 |
4 |
|
| active_d3_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 3
111478
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
2 |
2 |
2 |
2 |
1 |
2 |
2 |
2 |
1 |
2 |
|
1 |
2 |
1 |
|
3 |
|
1 |
|
1 |
2 |
1 |
2 |
3 |
|
3 |
1 |
1 |
1 |
3 |
1 |
3 |
3 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
2 |
2 |
1 |
4 |
| (M) |
2 |
|
2 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
4 |
|
| active_d4_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 4
111479
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
3 |
1 |
2 |
2 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
|
3 |
|
2 |
|
1 |
2 |
1 |
2 |
3 |
|
2 |
|
2 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
2 |
1 |
3 |
2 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
2 |
1 |
3 |
4 |
| (M) |
2 |
|
2 |
2 |
3 |
3 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
4 |
|
| active_d5_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 5
111480
|
(F) |
|
1 |
3 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
|
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
2 |
3 |
3 |
1 |
2 |
3 |
1 |
3 |
2 |
3 |
1 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
3 |
2 |
2 |
1 |
4 |
| (M) |
2 |
|
2 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
1 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
3 |
1 |
|
1 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
4 |
|
| active_d6_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 6
111481
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
1 |
1 |
|
3 |
3 |
1 |
2 |
3 |
|
1 |
2 |
3 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
|
2 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
2 |
4 |
|
| active_d7_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 7
111482
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
2 |
2 |
|
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
3 |
2 |
1 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
1 |
2 |
3 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
2 |
2 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| active_d8_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 8
111483
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
3 |
1 |
|
2 |
2 |
1 |
2 |
|
1 |
3 |
2 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
3 |
1 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
|
1 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
2 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
|
4 |
|
| active_d9_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 9
111484
|
(F) |
1 |
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
1 |
|
3 |
3 |
2 |
2 |
3 |
1 |
|
2 |
2 |
1 |
2 |
|
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
2 |
1 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
2 |
3 |
2 |
3 |
1 |
3 |
2 |
2 |
2 |
4 |
| (M) |
2 |
|
1 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
|
3 |
4 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
2 |
|
2 |
2 |
1 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
|
2 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
4 |
|
| active_d10_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration), cocaine
, day 10
111485
|
(F) |
|
1 |
3 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
1 |
3 |
|
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
4 |
| (M) |
2 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
4 |
2 |
1 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
|
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| active_d1_4_control number of active lever presses (during infusions and timeouts) (intravenous self administration) combined, saline
, days 1-4
111486
|
(F) |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
2 |
3 |
3 |
3 |
4 |
3 |
2 |
2 |
1 |
2 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| active_d5_7_control number of active lever presses (during infusions and timeouts) (intravenous self administration) combined, saline
, days 5-7
111487
|
(F) |
|
|
2 |
3 |
3 |
3 |
3 |
1 |
1 |
2 |
2 |
3 |
|
|
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
2 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
| (M) |
2 |
1 |
3 |
3 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
|
| active_d8_10_control number of active lever presses (during infusions and timeouts) (intravenous self administration) combined, saline
, days 8-10
111488
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
1 |
3 |
| (M) |
1 |
1 |
3 |
3 |
3 |
4 |
2 |
2 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
2 |
3 |
|
| active_d1_4_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration) combined, cocaine
, days 1-4
111489
|
(F) |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
4 |
4 |
| (M) |
2 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| active_d5_7_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration) combined, cocaine
, days 5-7
111490
|
(F) |
|
2 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
1 |
1 |
|
3 |
3 |
2 |
2 |
3 |
2 |
2 |
2 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
|
3 |
2 |
3 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
|
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
|
1 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
|
| active_d8_10_cocaine number of active lever presses (during infusions and timeouts) (intravenous self administration) combined, cocaine
, days 8-10
111491
|
(F) |
1 |
1 |
3 |
2 |
3 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
2 |
1 |
2 |
|
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
4 |
| (M) |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
4 |
2 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
|
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
4 |
|
| inactive_d1_control number of inactive lever presses (intravenous self administration), saline
, day 1
111492
|
(F) |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
2 |
1 |
2 |
2 |
2 |
|
1 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
2 |
2 |
2 |
3 |
|
1 |
1 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
2 |
3 |
| (M) |
2 |
3 |
2 |
3 |
3 |
4 |
3 |
1 |
2 |
|
|
3 |
1 |
1 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
2 |
|
1 |
3 |
3 |
1 |
3 |
2 |
1 |
|
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
2 |
2 |
3 |
2 |
2 |
3 |
2 |
3 |
4 |
2 |
3 |
3 |
2 |
2 |
3 |
|
| inactive_d2_control number of inactive lever presses (intravenous self administration), saline
, day 2
111493
|
(F) |
1 |
|
2 |
3 |
3 |
2 |
3 |
|
1 |
1 |
2 |
2 |
1 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
1 |
1 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
|
2 |
2 |
4 |
1 |
2 |
3 |
2 |
3 |
2 |
2 |
1 |
2 |
|
3 |
1 |
1 |
1 |
2 |
2 |
1 |
1 |
3 |
|
2 |
| (M) |
|
1 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
|
3 |
3 |
1 |
1 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
|
2 |
1 |
1 |
3 |
2 |
2 |
2 |
2 |
1 |
1 |
1 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
4 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
2 |
3 |
1 |
2 |
2 |
3 |
|
| inactive_d3_control number of inactive lever presses (intravenous self administration), saline
, day 3
111494
|
(F) |
1 |
|
1 |
3 |
3 |
3 |
3 |
|
1 |
2 |
1 |
2 |
1 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
2 |
1 |
2 |
2 |
|
3 |
1 |
1 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
2 |
|
3 |
|
3 |
3 |
4 |
|
2 |
3 |
2 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
1 |
2 |
2 |
2 |
1 |
3 |
2 |
3 |
|
2 |
| (M) |
1 |
|
3 |
2 |
3 |
4 |
2 |
1 |
2 |
|
2 |
3 |
1 |
1 |
|
3 |
2 |
2 |
3 |
|
3 |
3 |
3 |
|
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
|
1 |
3 |
2 |
|
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
4 |
2 |
1 |
3 |
2 |
1 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
3 |
|
| inactive_d4_control number of inactive lever presses (intravenous self administration), saline
, day 4
111495
|
(F) |
|
|
2 |
3 |
3 |
2 |
3 |
1 |
1 |
3 |
1 |
2 |
|
|
3 |
3 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
2 |
2 |
2 |
2 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
|
3 |
2 |
4 |
2 |
1 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
2 |
1 |
3 |
2 |
|
3 |
| (M) |
|
1 |
2 |
3 |
3 |
4 |
2 |
1 |
2 |
1 |
2 |
3 |
|
|
|
3 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
|
1 |
3 |
2 |
2 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
2 |
2 |
2 |
2 |
2 |
3 |
3 |
1 |
1 |
2 |
2 |
1 |
2 |
|
3 |
|
| inactive_d5_control number of inactive lever presses (intravenous self administration), saline
, day 5
111496
|
(F) |
|
|
2 |
2 |
3 |
3 |
2 |
|
1 |
2 |
1 |
2 |
|
1 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
|
2 |
2 |
3 |
1 |
1 |
2 |
1 |
1 |
1 |
1 |
1 |
3 |
2 |
|
3 |
|
3 |
2 |
4 |
1 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
2 |
2 |
3 |
1 |
1 |
2 |
3 |
3 |
1 |
1 |
3 |
|
3 |
| (M) |
1 |
1 |
2 |
|
3 |
4 |
1 |
|
2 |
1 |
3 |
2 |
1 |
1 |
1 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
1 |
1 |
2 |
2 |
2 |
2 |
3 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
3 |
|
| inactive_d6_control number of inactive lever presses (intravenous self administration), saline
, day 6
111497
|
(F) |
|
|
1 |
2 |
3 |
2 |
3 |
1 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
|
2 |
1 |
2 |
1 |
2 |
2 |
1 |
2 |
1 |
1 |
1 |
3 |
1 |
|
3 |
|
2 |
2 |
4 |
3 |
3 |
3 |
2 |
3 |
2 |
1 |
|
3 |
2 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
1 |
3 |
|
3 |
| (M) |
|
|
2 |
2 |
3 |
4 |
1 |
|
2 |
1 |
3 |
2 |
|
1 |
2 |
3 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
2 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
4 |
3 |
1 |
3 |
2 |
3 |
2 |
2 |
1 |
2 |
2 |
2 |
3 |
2 |
|
3 |
|
| inactive_d7_control number of inactive lever presses (intravenous self administration), saline
, day 7
111498
|
(F) |
|
|
2 |
2 |
3 |
3 |
1 |
|
1 |
1 |
1 |
|
|
1 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
1 |
2 |
2 |
1 |
1 |
2 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
2 |
|
3 |
|
2 |
2 |
3 |
2 |
3 |
3 |
2 |
3 |
2 |
2 |
|
3 |
2 |
3 |
1 |
2 |
2 |
3 |
3 |
3 |
|
3 |
|
3 |
| (M) |
2 |
1 |
1 |
2 |
3 |
4 |
3 |
1 |
2 |
1 |
3 |
1 |
1 |
1 |
1 |
2 |
3 |
2 |
3 |
|
3 |
3 |
3 |
1 |
2 |
|
1 |
3 |
3 |
2 |
2 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
|
2 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
1 |
1 |
3 |
2 |
3 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
1 |
3 |
|
| inactive_d8_control number of inactive lever presses (intravenous self administration), saline
, day 8
111499
|
(F) |
|
1 |
2 |
1 |
3 |
3 |
2 |
|
1 |
2 |
1 |
1 |
|
1 |
3 |
3 |
1 |
3 |
3 |
2 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
2 |
|
3 |
1 |
3 |
1 |
4 |
1 |
2 |
3 |
2 |
3 |
3 |
1 |
|
3 |
2 |
1 |
2 |
1 |
1 |
3 |
3 |
3 |
1 |
3 |
1 |
3 |
| (M) |
1 |
|
2 |
1 |
3 |
3 |
2 |
|
2 |
1 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
2 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
1 |
2 |
2 |
3 |
3 |
2 |
2 |
3 |
3 |
4 |
2 |
1 |
2 |
2 |
3 |
2 |
2 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
|
| inactive_d9_control number of inactive lever presses (intravenous self administration), saline
, day 9
111500
|
(F) |
|
|
3 |
2 |
3 |
3 |
3 |
|
1 |
2 |
1 |
|
|
1 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
4 |
2 |
3 |
3 |
2 |
3 |
2 |
2 |
2 |
3 |
2 |
3 |
2 |
2 |
2 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
| (M) |
1 |
|
2 |
2 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
2 |
|
1 |
2 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
2 |
2 |
3 |
2 |
1 |
1 |
1 |
1 |
1 |
3 |
3 |
|
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
4 |
2 |
2 |
2 |
2 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
3 |
|
| inactive_d10_control number of inactive lever presses (intravenous self administration), saline
, day 10
111501
|
(F) |
|
|
2 |
2 |
3 |
3 |
2 |
|
1 |
1 |
1 |
|
|
|
3 |
3 |
2 |
3 |
3 |
3 |
1 |
3 |
3 |
2 |
1 |
|
2 |
3 |
3 |
1 |
2 |
3 |
1 |
1 |
1 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
4 |
3 |
3 |
3 |
2 |
3 |
2 |
2 |
1 |
3 |
2 |
2 |
1 |
1 |
2 |
3 |
2 |
3 |
|
3 |
|
3 |
| (M) |
1 |
1 |
2 |
|
3 |
4 |
2 |
2 |
2 |
1 |
3 |
2 |
1 |
1 |
2 |
2 |
2 |
2 |
3 |
|
3 |
2 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
1 |
1 |
1 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
2 |
1 |
2 |
1 |
3 |
1 |
2 |
3 |
3 |
2 |
2 |
2 |
2 |
2 |
3 |
|
| inactive_d1_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 1
111502
|
(F) |
|
2 |
2 |
2 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
1 |
2 |
3 |
|
2 |
|
1 |
3 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
2 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
4 |
| (M) |
2 |
2 |
2 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
4 |
2 |
1 |
3 |
3 |
1 |
3 |
3 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
4 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
2 |
1 |
3 |
3 |
2 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| inactive_d2_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 2
111503
|
(F) |
|
1 |
2 |
2 |
3 |
1 |
3 |
2 |
2 |
|
1 |
2 |
1 |
|
3 |
3 |
2 |
2 |
2 |
|
|
1 |
2 |
|
2 |
|
|
2 |
3 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
2 |
|
2 |
1 |
2 |
2 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
2 |
2 |
1 |
2 |
3 |
2 |
2 |
3 |
1 |
2 |
1 |
2 |
3 |
4 |
| (M) |
2 |
1 |
3 |
2 |
2 |
3 |
3 |
2 |
1 |
1 |
1 |
2 |
2 |
1 |
3 |
4 |
3 |
1 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
2 |
1 |
1 |
2 |
2 |
|
1 |
1 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| inactive_d3_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 3
111504
|
(F) |
|
|
3 |
1 |
3 |
3 |
2 |
2 |
2 |
|
2 |
2 |
1 |
|
2 |
2 |
3 |
2 |
2 |
2 |
2 |
2 |
2 |
1 |
2 |
1 |
|
2 |
3 |
|
2 |
|
1 |
|
1 |
1 |
1 |
2 |
3 |
|
3 |
1 |
3 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
|
2 |
2 |
2 |
3 |
3 |
3 |
3 |
|
3 |
1 |
2 |
|
4 |
| (M) |
1 |
|
2 |
2 |
1 |
3 |
3 |
1 |
1 |
1 |
|
3 |
2 |
|
3 |
3 |
3 |
|
2 |
3 |
1 |
2 |
3 |
2 |
1 |
|
2 |
2 |
1 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
1 |
3 |
|
2 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
|
3 |
2 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
|
4 |
|
| inactive_d4_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 4
111505
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
1 |
|
|
2 |
2 |
1 |
1 |
3 |
3 |
|
2 |
2 |
|
2 |
2 |
1 |
|
1 |
|
|
2 |
3 |
1 |
3 |
1 |
2 |
1 |
|
2 |
1 |
2 |
3 |
|
2 |
1 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
3 |
|
2 |
2 |
2 |
2 |
3 |
2 |
3 |
2 |
3 |
3 |
2 |
1 |
4 |
| (M) |
1 |
|
1 |
3 |
3 |
3 |
3 |
1 |
|
1 |
|
2 |
2 |
1 |
3 |
4 |
3 |
|
3 |
3 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
1 |
1 |
1 |
2 |
3 |
|
1 |
2 |
1 |
2 |
3 |
2 |
2 |
3 |
1 |
1 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
1 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
|
| inactive_d5_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 5
111506
|
(F) |
1 |
|
3 |
1 |
3 |
2 |
3 |
1 |
2 |
1 |
3 |
1 |
1 |
|
3 |
3 |
1 |
2 |
3 |
1 |
2 |
2 |
3 |
|
2 |
|
|
1 |
1 |
|
2 |
|
2 |
|
1 |
2 |
1 |
3 |
2 |
1 |
2 |
1 |
2 |
1 |
3 |
1 |
1 |
3 |
1 |
2 |
3 |
2 |
2 |
2 |
1 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
1 |
|
3 |
| (M) |
2 |
|
2 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
|
3 |
2 |
|
3 |
4 |
3 |
1 |
3 |
2 |
1 |
1 |
2 |
2 |
1 |
2 |
2 |
1 |
1 |
|
3 |
1 |
|
2 |
1 |
1 |
2 |
2 |
2 |
1 |
3 |
1 |
2 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
|
2 |
1 |
3 |
2 |
2 |
2 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| inactive_d6_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 6
111507
|
(F) |
|
|
2 |
2 |
2 |
2 |
3 |
3 |
2 |
|
2 |
1 |
1 |
1 |
3 |
2 |
1 |
2 |
3 |
1 |
|
2 |
2 |
|
2 |
|
|
2 |
2 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
1 |
|
2 |
1 |
3 |
1 |
3 |
1 |
2 |
3 |
1 |
3 |
3 |
2 |
1 |
3 |
|
3 |
1 |
3 |
3 |
3 |
1 |
2 |
2 |
1 |
|
4 |
| (M) |
1 |
|
2 |
1 |
3 |
3 |
3 |
2 |
1 |
1 |
1 |
1 |
1 |
|
3 |
4 |
3 |
|
2 |
2 |
1 |
1 |
3 |
2 |
1 |
1 |
2 |
|
1 |
1 |
3 |
3 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
2 |
2 |
2 |
3 |
2 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
2 |
2 |
|
2 |
3 |
2 |
3 |
2 |
3 |
|
4 |
|
| inactive_d7_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 7
111508
|
(F) |
|
1 |
2 |
2 |
3 |
2 |
3 |
2 |
1 |
1 |
2 |
|
1 |
1 |
3 |
2 |
2 |
2 |
3 |
1 |
1 |
2 |
2 |
1 |
1 |
|
|
1 |
3 |
|
3 |
1 |
2 |
1 |
1 |
1 |
1 |
2 |
2 |
|
1 |
1 |
2 |
1 |
2 |
2 |
2 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
|
2 |
1 |
3 |
2 |
3 |
2 |
2 |
1 |
1 |
1 |
4 |
| (M) |
1 |
1 |
2 |
3 |
2 |
3 |
3 |
|
1 |
2 |
1 |
1 |
1 |
|
3 |
4 |
3 |
1 |
2 |
2 |
|
1 |
3 |
2 |
1 |
2 |
1 |
|
1 |
1 |
2 |
1 |
|
2 |
2 |
1 |
2 |
2 |
3 |
1 |
3 |
|
2 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
1 |
2 |
|
1 |
1 |
3 |
1 |
1 |
2 |
2 |
1 |
3 |
3 |
3 |
|
4 |
|
| inactive_d8_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 8
111509
|
(F) |
|
1 |
3 |
1 |
3 |
2 |
2 |
1 |
2 |
2 |
1 |
|
1 |
1 |
3 |
2 |
1 |
2 |
3 |
1 |
1 |
1 |
1 |
1 |
2 |
|
1 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
1 |
1 |
1 |
3 |
2 |
|
2 |
1 |
3 |
2 |
2 |
1 |
2 |
3 |
1 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
|
3 |
2 |
3 |
|
2 |
|
2 |
2 |
4 |
| (M) |
|
|
2 |
1 |
2 |
3 |
3 |
1 |
1 |
2 |
|
2 |
1 |
|
2 |
4 |
3 |
1 |
3 |
1 |
2 |
2 |
3 |
2 |
1 |
1 |
2 |
|
1 |
1 |
2 |
1 |
|
1 |
2 |
1 |
1 |
3 |
3 |
2 |
2 |
1 |
2 |
2 |
2 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
|
2 |
1 |
3 |
|
2 |
1 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| inactive_d9_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 9
111510
|
(F) |
|
|
2 |
2 |
3 |
3 |
3 |
2 |
2 |
1 |
2 |
|
1 |
1 |
3 |
1 |
2 |
2 |
3 |
1 |
1 |
2 |
1 |
1 |
1 |
|
|
2 |
3 |
|
2 |
1 |
2 |
1 |
1 |
1 |
1 |
2 |
2 |
|
1 |
1 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
3 |
1 |
|
1 |
2 |
2 |
1 |
3 |
2 |
3 |
|
2 |
1 |
1 |
2 |
3 |
| (M) |
2 |
|
3 |
2 |
2 |
2 |
3 |
1 |
1 |
1 |
1 |
1 |
2 |
|
2 |
4 |
2 |
1 |
3 |
2 |
1 |
1 |
3 |
2 |
1 |
1 |
1 |
|
1 |
1 |
2 |
1 |
|
1 |
1 |
1 |
2 |
1 |
3 |
2 |
1 |
1 |
2 |
2 |
2 |
3 |
2 |
2 |
3 |
3 |
2 |
2 |
1 |
2 |
1 |
2 |
2 |
|
1 |
3 |
2 |
3 |
2 |
3 |
|
4 |
|
| inactive_d10_cocaine number of inactive lever presses (intravenous self administration), cocaine
, day 10
111511
|
(F) |
|
1 |
3 |
|
3 |
3 |
3 |
2 |
1 |
1 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
2 |
3 |
1 |
2 |
1 |
2 |
1 |
2 |
1 |
1 |
2 |
3 |
|
2 |
|
2 |
1 |
1 |
2 |
1 |
2 |
3 |
|
1 |
1 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
2 |
|
2 |
3 |
3 |
1 |
1 |
1 |
1 |
2 |
3 |
| (M) |
1 |
|
1 |
3 |
2 |
3 |
3 |
1 |
1 |
1 |
|
2 |
2 |
|
2 |
3 |
2 |
1 |
2 |
2 |
|
1 |
3 |
2 |
1 |
|
1 |
|
1 |
1 |
2 |
2 |
|
1 |
2 |
1 |
2 |
2 |
3 |
2 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
2 |
3 |
2 |
2 |
1 |
|
2 |
1 |
3 |
1 |
1 |
2 |
2 |
2 |
3 |
1 |
3 |
|
3 |
|
| inactive_d1_4_control number of inactive lever presses (intravenous self administration) combined, saline
, days 1-4
111512
|
(F) |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
1 |
3 |
2 |
2 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
2 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
2 |
3 |
|
| inactive_d5_7_control number of inactive lever presses (intravenous self administration) combined, saline
, days 5-7
111513
|
(F) |
|
|
2 |
3 |
3 |
3 |
3 |
1 |
1 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
1 |
2 |
2 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
|
3 |
2 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
|
3 |
| (M) |
2 |
1 |
2 |
3 |
3 |
4 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
2 |
2 |
2 |
3 |
2 |
2 |
3 |
|
| inactive_d8_10_control number of inactive lever presses (intravenous self administration) combined, saline
, days 8-10
111514
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
|
1 |
2 |
1 |
1 |
|
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
2 |
3 |
1 |
1 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
2 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
| (M) |
1 |
1 |
2 |
2 |
3 |
4 |
3 |
2 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
4 |
3 |
2 |
2 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
2 |
2 |
2 |
3 |
3 |
|
| inactive_d1_4_cocaine number of inactive lever presses (intravenous self administration) combined, cocaine
, days 1-4
111515
|
(F) |
|
3 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
1 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
2 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| inactive_d5_7_cocaine number of inactive lever presses (intravenous self administration) combined, cocaine
, days 5-7
111516
|
(F) |
1 |
1 |
3 |
2 |
3 |
2 |
3 |
3 |
2 |
1 |
3 |
1 |
1 |
1 |
3 |
3 |
2 |
2 |
3 |
1 |
2 |
2 |
3 |
1 |
2 |
|
|
2 |
3 |
|
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
1 |
3 |
2 |
3 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
2 |
3 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
4 |
| (M) |
2 |
1 |
2 |
3 |
3 |
4 |
3 |
2 |
1 |
2 |
1 |
3 |
2 |
|
3 |
4 |
3 |
1 |
3 |
2 |
1 |
1 |
3 |
2 |
1 |
2 |
2 |
1 |
2 |
1 |
3 |
3 |
|
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
|
4 |
|
| inactive_d8_10_cocaine number of inactive lever presses (intravenous self administration) combined, cocaine
, days 8-10
111517
|
(F) |
|
1 |
3 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
1 |
1 |
1 |
3 |
3 |
2 |
2 |
3 |
1 |
2 |
2 |
3 |
1 |
2 |
1 |
1 |
2 |
3 |
1 |
2 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
|
2 |
1 |
3 |
3 |
3 |
1 |
3 |
3 |
1 |
3 |
3 |
3 |
2 |
2 |
2 |
3 |
1 |
3 |
3 |
3 |
1 |
3 |
2 |
2 |
3 |
4 |
| (M) |
2 |
|
3 |
3 |
2 |
3 |
3 |
2 |
1 |
2 |
1 |
2 |
2 |
|
2 |
4 |
3 |
1 |
3 |
3 |
2 |
2 |
3 |
2 |
1 |
2 |
2 |
|
1 |
1 |
2 |
2 |
|
1 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
2 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
2 |
2 |
3 |
3 |
3 |
2 |
3 |
|
4 |
|
| session_time_d1_control session duration (120 min max) (intravenous self administration), saline
, day 1
111518
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d2_control session duration (120 min max) (intravenous self administration), saline
, day 2
111519
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d3_control session duration (120 min max) (intravenous self administration), saline
, day 3
111520
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d4_control session duration (120 min max) (intravenous self administration), saline
, day 4
111521
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d5_control session duration (120 min max) (intravenous self administration), saline
, day 5
111522
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d6_control session duration (120 min max) (intravenous self administration), saline
, day 6
111523
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
2 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d7_control session duration (120 min max) (intravenous self administration), saline
, day 7
111524
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d8_control session duration (120 min max) (intravenous self administration), saline
, day 8
111525
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d9_control session duration (120 min max) (intravenous self administration), saline
, day 9
111526
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d10_control session duration (120 min max) (intravenous self administration), saline
, day 10
111527
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d1_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 1
111528
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d2_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 2
111529
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d3_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 3
111530
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d4_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 4
111531
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d5_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 5
111532
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d6_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 6
111533
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d7_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 7
111534
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d8_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 8
111535
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d9_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 9
111536
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d10_cocaine session duration (120 min max) (intravenous self administration), cocaine
, day 10
111537
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d1_4_control session duration (120 min max) (intravenous self administration) combined, saline
, days 1-4
111538
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d5_7_control session duration (120 min max) (intravenous self administration) combined, saline
, days 5-7
111539
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d8_10_control session duration (120 min max) (intravenous self administration) combined, saline
, days 8-10
111540
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
2 |
3 |
1 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
3 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
1 |
3 |
3 |
|
3 |
1 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
2 |
1 |
3 |
4 |
1 |
2 |
2 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
2 |
3 |
2 |
1 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
4 |
2 |
3 |
3 |
2 |
3 |
3 |
|
| session_time_d1_4_cocaine session duration (120 min max) (intravenous self administration) combined, cocaine
, days 1-4
111541
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d5_7_cocaine session duration (120 min max) (intravenous self administration) combined, cocaine
, days 5-7
111542
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
| session_time_d8_10_cocaine session duration (120 min max) (intravenous self administration) combined, cocaine
, days 8-10
111543
|
(F) |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
1 |
2 |
3 |
3 |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
1 |
2 |
1 |
1 |
3 |
3 |
1 |
3 |
1 |
2 |
1 |
1 |
2 |
1 |
3 |
3 |
1 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
4 |
4 |
| (M) |
2 |
3 |
3 |
3 |
3 |
4 |
3 |
3 |
1 |
2 |
1 |
3 |
2 |
1 |
3 |
4 |
3 |
1 |
3 |
3 |
3 |
3 |
3 |
2 |
1 |
2 |
2 |
3 |
2 |
1 |
3 |
3 |
1 |
2 |
2 |
1 |
2 |
3 |
3 |
2 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
1 |
3 |
3 |
3 |
4 |
3 |
3 |
3 |
3 |
3 |
3 |
4 |
|
