MPD: Project measure / variable: Project1032 active_pct_d5

Project measure / variable: Project1032 active_pct_d5_control

ID, description, units	MPD:111444 active_pct_d5_control percentage of lever presses that are active (intravenous self administration), saline [%] day 5
Data set, strains	Project1032 HMDP 63 strains sex: both age: 9-15wks
Procedure	operant conditioning chamber
Ontology mappings

STRAIN COMPARISON PLOT

Dimensions Width: px Height: px

Download Plot

Visualization Options Least squares means Alphabetical order Strains on X-axis Individual points

Project1032 - percentage of lever presses that are active (intravenous self administration), saline day 5

MEASURE SUMMARY

Measure Summary	Female	Male
Number of strains tested	59 strains	63 strains
Mean of the strain means	61.84 %	63.1 %
Median of the strain means	59.87 %	62.5 %
SD of the strain means	± 19.736	± 18.237
Coefficient of variation (CV)	0.3191	0.289
Min–max range of strain means	28.7 – 100.0 %	19.0 – 100.0 %
Mean sample size per strain	2.2 mice	2.1 mice

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p value (Pr>F)
sex	1	41.1279	41.1279	0.078	0.7805
strain	35	34658.492	990.2426	1.8782	0.0065
sex:strain	35	14799.4597	422.8417	0.802	0.771
Residuals	119	62739.4542	527.2223

Q-Q normality assessment based on residuals

STRAIN MEANS (UNADJUSTED)

Strain	Sex	Mean	SD	N mice	SEM	CV	Min, Max	Z score
A/J	f	71.35	3.6062	2	2.55	0.0505	68.8, 73.9	0.48
A/J	m	74.07	27.987	3	16.159	0.3779	44.4, 100.0	0.6
AKR/J	f	31.75	9.5459	2	6.75	0.3007	25.0, 38.5	-1.52
AKR/J	m	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.02
BALB/cByJ	f	39.333	26.818	3	15.483	0.6818	13.1, 66.7	-1.14
BALB/cByJ	m	51.07	30.968	3	17.88	0.6064	25.0, 85.3	-0.66
BALB/cJ	f	56.87	28.331	3	16.357	0.4982	32.6, 88.0	-0.25
BALB/cJ	m	66.4	20.557	4	10.279	0.3096	45.9, 85.7	0.18
BPL/1J	f	62.6	34.08	3	19.676	0.5444	33.3, 100.0	0.04
BPL/1J	m	65.1	49.356	2	34.9	0.7582	30.2, 100.0	0.11
BTBR T⁺ Itpr3^tf/J	f	100.0	0.0	1	0.0	0.0	100.0, 100.0	1.93
BTBR T⁺ Itpr3^tf/J	m	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.02
BXD100/RwwJ	f	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.6
BXD100/RwwJ	m	53.75	11.526	2	8.15	0.2144	45.6, 61.9	-0.51
BXD11/TyJ	f	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.6
BXD11/TyJ	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.72
BXD15/TyJ	f	88.55	16.193	2	11.45	0.1829	77.1, 100.0	1.35
BXD15/TyJ	m	83.2	7.2794	3	4.2028	0.0875	75.0, 88.9	1.1
BXD1/TyJ	f	94.45	7.8489	2	5.55	0.0831	88.9, 100.0	1.65
BXD1/TyJ	m	85.0	13.229	3	7.6376	0.1556	75.0, 100.0	1.2
BXD21/TyJ	m	75.0	0.0	1	0.0	0.0	75.0, 75.0	0.65
BXD28/TyJ	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.72
BXD2/TyJ	f	35.4	44.265	2	31.3	1.2504	4.1, 66.7	-1.34
BXD2/TyJ	m	62.5	53.03	2	37.5	0.8485	25.0, 100.0	-0.03
BXD31/TyJ	f	67.8	14.142	2	10.0	0.2086	57.8, 77.8	0.3
BXD31/TyJ	m	54.4	6.2225	2	4.4	0.1144	50.0, 58.8	-0.48
BXD32/TyJ	f	38.1	6.7882	2	4.8	0.1782	33.3, 42.9	-1.2
BXD32/TyJ	m	77.3	3.2527	2	2.3	0.0421	75.0, 79.6	0.78
BXD34/TyJ	f	82.25	16.334	2	11.55	0.1986	70.7, 93.8	1.03
BXD34/TyJ	m	60.5	14.849	2	10.5	0.2454	50.0, 71.0	-0.14
BXD38/TyJ	f	74.7	9.057	3	5.2291	0.1212	67.3, 84.8	0.65
BXD38/TyJ	m	48.233	19.619	3	11.327	0.4068	33.1, 70.4	-0.82
BXD39/TyJ	f	47.867	24.032	3	13.875	0.5021	20.8, 66.7	-0.71
BXD39/TyJ	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.72
BXD40/TyJ	f	59.5	10.9	3	6.2931	0.1832	50.0, 71.4	-0.12
BXD40/TyJ	m	46.167	32.985	3	19.044	0.7145	16.7, 81.8	-0.93
BXD42/TyJ	f	46.4	34.741	3	20.058	0.7487	25.4, 86.5	-0.78
BXD42/TyJ	m	48.9	28.188	3	16.275	0.5765	16.4, 66.7	-0.78
BXD48a/RwwJ	f	40.6	32.035	3	18.496	0.7891	10.0, 73.9	-1.08
BXD48a/RwwJ	m	29.533	13.313	3	7.686	0.4508	21.5, 44.9	-1.84
BXD50/RwwJ	f	52.7	0.84853	2	0.6	0.0161	52.1, 53.3	-0.46
BXD50/RwwJ	m	89.5	0.0	1	0.0	0.0	89.5, 89.5	1.45
BXD55/RwwJ	f	69.0	0.0	1	0.0	0.0	69.0, 69.0	0.36
BXD55/RwwJ	m	46.4	34.224	2	24.2	0.7376	22.2, 70.6	-0.92
BXD56/RwwJ	f	100.0	0.0	1	0.0	0.0	100.0, 100.0	1.93
BXD56/RwwJ	m	85.2	0.0	1	0.0	0.0	85.2, 85.2	1.21
BXD60/RwwJ	f	49.0	25.032	2	17.7	0.5108	31.3, 66.7	-0.65
BXD60/RwwJ	m	71.9	0.0	1	0.0	0.0	71.9, 71.9	0.48
BXD61/RwwJ	f	35.5	0.0	1	0.0	0.0	35.5, 35.5	-1.33
BXD61/RwwJ	m	68.9	9.0537	3	5.2272	0.1314	59.7, 77.8	0.32
BXD62/RwwJ	f	62.13	19.252	3	11.115	0.3099	40.0, 75.0	0.01
BXD62/RwwJ	m	59.07	7.852	3	4.5333	0.1329	50.0, 63.6	-0.22
BXD63/RwwJ	f	30.8	0.0	1	0.0	0.0	30.8, 30.8	-1.57
BXD63/RwwJ	m	85.75	16.334	2	11.55	0.1905	74.2, 97.3	1.24
BXD65/RwwJ	f	90.33	16.743	3	9.6667	0.1853	71.0, 100.0	1.44
BXD65/RwwJ	m	19.0	0.0	1	0.0	0.0	19.0, 19.0	-2.42
BXD68/RwwJ	f	70.1	7.4953	2	5.3	0.1069	64.8, 75.4	0.42
BXD68/RwwJ	m	50.75	15.203	2	10.75	0.2996	40.0, 61.5	-0.68
BXD69/RwwJ	f	87.8	0.0	1	0.0	0.0	87.8, 87.8	1.32
BXD69/RwwJ	m	80.0	0.0	1	0.0	0.0	80.0, 80.0	0.93
BXD70/RwwJ	f	59.45	57.35	2	40.55	0.9646	18.9, 100.0	-0.12
BXD70/RwwJ	m	87.8	0.0	1	0.0	0.0	87.8, 87.8	1.35
BXD71/RwwJ	f	69.7	42.851	2	30.3	0.6148	39.4, 100.0	0.4
BXD71/RwwJ	m	57.7	0.0	1	0.0	0.0	57.7, 57.7	-0.3
BXD73a/RwwJ	f	82.1	0.0	1	0.0	0.0	82.1, 82.1	1.03
BXD73a/RwwJ	m	89.7	3.1113	2	2.2	0.0347	87.5, 91.9	1.46
BXD75/RwwJ	f	62.1	0.0	1	0.0	0.0	62.1, 62.1	0.01
BXD75/RwwJ	m	69.2	0.0	1	0.0	0.0	69.2, 69.2	0.33
BXD77/RwwJ	f	61.97	24.024	3	13.87	0.3877	44.2, 89.3	0.01
BXD77/RwwJ	m	61.1	4.8539	3	2.8024	0.0794	58.1, 66.7	-0.11
BXD84/RwwJ	f	70.73	26.069	3	15.051	0.3686	50.0, 100.0	0.45
BXD84/RwwJ	m	56.53	3.107	3	1.7938	0.055	54.0, 60.0	-0.36
BXD90/RwwJ	m	22.2	0.0	1	0.0	0.0	22.2, 22.2	-2.24
BXD98/RwwJ	f	78.97	9.8541	3	5.6893	0.1248	67.6, 85.1	0.87
BXD98/RwwJ	m	59.77	31.517	3	18.196	0.5273	26.8, 89.6	-0.18
C3HeB/FeJ	f	56.87	28.131	3	16.242	0.4947	27.3, 83.3	-0.25
C3HeB/FeJ	m	86.7	0.0	1	0.0	0.0	86.7, 86.7	1.29
C3H/HeJ	f	65.47	37.85	3	21.853	0.5782	25.0, 100.0	0.18
C3H/HeJ	m	57.8	18.996	3	10.967	0.3286	40.0, 77.8	-0.29
C57BL/10J	f	48.175	9.2651	4	4.6326	0.1923	35.3, 57.4	-0.69
C57BL/10J	m	64.37	20.565	3	11.873	0.3195	48.5, 87.6	0.07
C57BL/6J	f	94.13	10.161	3	5.8667	0.1079	82.4, 100.0	1.64
C57BL/6J	m	59.2	20.85	3	12.038	0.3522	38.3, 80.0	-0.21
C57BLKS/J	f	75.0	0.0	1	0.0	0.0	75.0, 75.0	0.67
C57BLKS/J	m	62.5	17.678	2	12.5	0.2828	50.0, 75.0	-0.03
C57BR/cdJ	f	51.7	29.412	3	16.981	0.5689	18.0, 72.2	-0.51
C57BR/cdJ	m	57.5	36.214	3	20.908	0.6298	16.1, 83.3	-0.31
C57L/J	f	55.85	18.738	2	13.25	0.3355	42.6, 69.1	-0.3
C57L/J	m	71.97	17.471	3	10.087	0.2428	51.8, 82.5	0.49
C58/J	f	43.867	9.6147	3	5.5511	0.2192	33.3, 52.1	-0.91
C58/J	m	24.2	22.735	3	13.126	0.9395	7.1, 50.0	-2.13
CBA/J	f	57.1	27.224	3	15.718	0.4768	27.0, 80.0	-0.24
CBA/J	m	54.3	20.445	3	11.804	0.3765	30.8, 68.0	-0.48
DBA/1J	f	42.9	0.0	1	0.0	0.0	42.9, 42.9	-0.96
DBA/1J	m	66.7	0.0	1	0.0	0.0	66.7, 66.7	0.2
DBA/2J	f	65.65	22.132	2	15.65	0.3371	50.0, 81.3	0.19
DBA/2J	m	73.9	0.0	1	0.0	0.0	73.9, 73.9	0.59
FVB/NJ	f	31.1	20.365	2	14.4	0.6548	16.7, 45.5	-1.56
FVB/NJ	m	29.55	21.85	2	15.45	0.7394	14.1, 45.0	-1.84
I/LnJ	f	56.95	1.7678	2	1.25	0.031	55.7, 58.2	-0.25
I/LnJ	m	65.75	35.002	2	24.75	0.5323	41.0, 90.5	0.15
KK/HlJ	f	59.87	14.786	3	8.5367	0.247	42.9, 70.0	-0.1
KK/HlJ	m	90.33	13.429	3	7.7531	0.1487	75.0, 100.0	1.49
LP/J	f	70.0	42.426	2	30.0	0.6061	40.0, 100.0	0.41
LP/J	m	74.83	22.051	3	12.731	0.2947	58.9, 100.0	0.64
MA/MyJ	f	81.95	25.527	2	18.05	0.3115	63.9, 100.0	1.02
MA/MyJ	m	40.133	24.255	3	14.004	0.6044	12.5, 57.9	-1.26
MRL/MpJ	m	84.43	13.891	3	8.02	0.1645	73.3, 100.0	1.17
NOD/ShiLtJ	f	28.7	18.462	3	10.659	0.6433	17.3, 50.0	-1.68
NOD/ShiLtJ	m	46.85	25.809	2	18.25	0.5509	28.6, 65.1	-0.89
NZB/BlNJ	f	52.5	38.891	2	27.5	0.7408	25.0, 80.0	-0.47
NZB/BlNJ	m	58.65	26.375	2	18.65	0.4497	40.0, 77.3	-0.24
NZO/HlLtJ	f	33.3	0.0	1	0.0	0.0	33.3, 33.3	-1.45
NZO/HlLtJ	m	66.05	6.4347	2	4.55	0.0974	61.5, 70.6	0.16
NZW/LacJ	f	100.0	0.0	2	0.0	0.0	100.0, 100.0	1.93
NZW/LacJ	m	75.0	35.355	2	25.0	0.4714	50.0, 100.0	0.65
PL/J	f	44.367	14.709	3	8.4924	0.3315	30.8, 60.0	-0.89
PL/J	m	70.1	2.9698	2	2.1	0.0424	68.0, 72.2	0.38
SJL/J	f	100.0	0.0	1	0.0	0.0	100.0, 100.0	1.93
SJL/J	m	45.0	7.0711	2	5.0	0.1571	40.0, 50.0	-0.99
SM/J	f	63.33	15.275	3	8.8192	0.2412	50.0, 80.0	0.08
SM/J	m	57.7	12.565	3	7.2547	0.2178	50.0, 72.2	-0.3

LEAST SQUARES MEANS (MODEL-ADJUSTED)

Strain	Sex	Mean	SEM	UpperCL	LowerCL
A/J	f	71.35	16.2361064286	103.4991123334	39.2008876666
A/J	m	74.0666666667	13.2567253865	100.3163069668	47.8170263666
BALB/cByJ	f	39.3333333333	13.2567253865	65.5829736334	13.0836930332
BALB/cByJ	m	51.0666666667	13.2567253865	77.3163069668	24.8170263666
BALB/cJ	f	56.8666666667	13.2567253865	83.1163069668	30.6170263666
BALB/cJ	m	66.4	11.4806609557	89.1328553401	43.6671446599
BPL/1J	f	62.6	13.2567253865	88.8496403001	36.3503596999
BPL/1J	m	65.1	16.2361064286	97.2491123334	32.9508876666
BXD15/TyJ	f	88.55	16.2361064286	120.6991123334	56.4008876666
BXD15/TyJ	m	83.2	13.2567253865	109.4496403001	56.9503596999
BXD1/TyJ	f	94.45	16.2361064286	126.5991123334	62.3008876666
BXD1/TyJ	m	85.0	13.2567253865	111.2496403001	58.7503596999
BXD2/TyJ	f	35.4	16.2361064286	67.5491123334	3.2508876666
BXD2/TyJ	m	62.5	16.2361064286	94.6491123334	30.3508876666
BXD31/TyJ	f	67.8	16.2361064286	99.9491123334	35.6508876666
BXD31/TyJ	m	54.4	16.2361064286	86.5491123334	22.2508876666
BXD32/TyJ	f	38.1	16.2361064286	70.2491123334	5.9508876666
BXD32/TyJ	m	77.3	16.2361064286	109.4491123334	45.1508876666
BXD34/TyJ	f	82.25	16.2361064286	114.3991123334	50.1008876666
BXD34/TyJ	m	60.5	16.2361064286	92.6491123334	28.3508876666
BXD38/TyJ	f	74.7	13.2567253865	100.9496403001	48.4503596999
BXD38/TyJ	m	48.2333333333	13.2567253865	74.4829736334	21.9836930332
BXD40/TyJ	f	59.5	13.2567253865	85.7496403001	33.2503596999
BXD40/TyJ	m	46.1666666667	13.2567253865	72.4163069668	19.9170263666
BXD42/TyJ	f	46.4	13.2567253865	72.6496403001	20.1503596999
BXD42/TyJ	m	48.9	13.2567253865	75.1496403001	22.6503596999
BXD48a/RwwJ	f	40.6	13.2567253865	66.8496403001	14.3503596999
BXD48a/RwwJ	m	29.5333333333	13.2567253865	55.7829736334	3.2836930332
BXD62/RwwJ	f	62.1333333333	13.2567253865	88.3829736334	35.8836930332
BXD62/RwwJ	m	59.0666666667	13.2567253865	85.3163069668	32.8170263666
BXD68/RwwJ	f	70.1	16.2361064286	102.2491123334	37.9508876666
BXD68/RwwJ	m	50.75	16.2361064286	82.8991123334	18.6008876666
BXD77/RwwJ	f	61.9666666667	13.2567253865	88.2163069668	35.7170263666
BXD77/RwwJ	m	61.1	13.2567253865	87.3496403001	34.8503596999
BXD84/RwwJ	f	70.7333333333	13.2567253865	96.9829736334	44.4836930332
BXD84/RwwJ	m	56.5333333333	13.2567253865	82.7829736334	30.2836930332
BXD98/RwwJ	f	78.9666666667	13.2567253865	105.2163069668	52.7170263666
BXD98/RwwJ	m	59.7666666667	13.2567253865	86.0163069668	33.5170263666
C3H/HeJ	f	65.4666666667	13.2567253865	91.7163069668	39.2170263666
C3H/HeJ	m	57.8	13.2567253865	84.0496403001	31.5503596999
C57BL/10J	f	48.175	11.4806609557	70.9078553401	25.4421446599
C57BL/10J	m	64.3666666667	13.2567253865	90.6163069668	38.1170263666
C57BL/6J	f	94.1333333333	13.2567253865	120.3829736334	67.8836930332
C57BL/6J	m	59.2	13.2567253865	85.4496403001	32.9503596999
C57BR/cdJ	f	51.7	13.2567253865	77.9496403001	25.4503596999
C57BR/cdJ	m	57.5	13.2567253865	83.7496403001	31.2503596999
C57L/J	f	55.85	16.2361064286	87.9991123334	23.7008876666
C57L/J	m	71.9666666667	13.2567253865	98.2163069668	45.7170263666
C58/J	f	43.8666666667	13.2567253865	70.1163069668	17.6170263666
C58/J	m	24.2	13.2567253865	50.4496403001	-2.0496403001
CBA/J	f	57.1	13.2567253865	83.3496403001	30.8503596999
CBA/J	m	54.3	13.2567253865	80.5496403001	28.0503596999
FVB/NJ	f	31.1	16.2361064286	63.2491123334	-1.0491123334
FVB/NJ	m	29.55	16.2361064286	61.6991123334	-2.5991123334
I/LnJ	f	56.95	16.2361064286	89.0991123334	24.8008876666
I/LnJ	m	65.75	16.2361064286	97.8991123334	33.6008876666
KK/HlJ	f	59.8666666667	13.2567253865	86.1163069668	33.6170263666
KK/HlJ	m	90.3333333333	13.2567253865	116.5829736334	64.0836930332
LP/J	f	70.0	16.2361064286	102.1491123334	37.8508876666
LP/J	m	74.8333333333	13.2567253865	101.0829736334	48.5836930332
MA/MyJ	f	81.95	16.2361064286	114.0991123334	49.8008876666
MA/MyJ	m	40.1333333333	13.2567253865	66.3829736334	13.8836930332
NOD/ShiLtJ	f	28.7	13.2567253865	54.9496403001	2.4503596999
NOD/ShiLtJ	m	46.85	16.2361064286	78.9991123334	14.7008876666
NZB/BlNJ	f	52.5	16.2361064286	84.6491123334	20.3508876666
NZB/BlNJ	m	58.65	16.2361064286	90.7991123334	26.5008876666
NZW/LacJ	f	100.0	16.2361064286	132.1491123334	67.8508876666
NZW/LacJ	m	75.0	16.2361064286	107.1491123334	42.8508876666
PL/J	f	44.3666666667	13.2567253865	70.6163069668	18.1170263666
PL/J	m	70.1	16.2361064286	102.2491123334	37.9508876666
SM/J	f	63.3333333333	13.2567253865	89.5829736334	37.0836930332
SM/J	m	57.7	13.2567253865	83.9496403001	31.4503596999

LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED

Strain	Sex	Mean	SEM	UpperCL	LowerCL
A/J	both	72.7083333333	10.4803616342	93.4604961104	51.9561705562
BALB/cByJ	both	45.2	9.3739204171	63.7612986599	26.6387013401
BALB/cJ	both	61.6333333333	8.768499643	78.9958383931	44.2708282736
BPL/1J	both	63.85	10.4803616342	84.6021627771	43.0978372229
BXD15/TyJ	both	85.875	10.4803616342	106.6271627771	65.1228372229
BXD1/TyJ	both	89.725	10.4803616342	110.4771627771	68.9728372229
BXD2/TyJ	both	48.95	11.4806609557	71.6828553401	26.2171446599
BXD31/TyJ	both	61.1	11.4806609557	83.8328553401	38.3671446599
BXD32/TyJ	both	57.7	11.4806609557	80.4328553401	34.9671446599
BXD34/TyJ	both	71.375	11.4806609557	94.1078553401	48.6421446599
BXD38/TyJ	both	61.4666666667	9.3739204171	80.0279653266	42.9053680068
BXD40/TyJ	both	52.8333333333	9.3739204171	71.3946319932	34.2720346734
BXD42/TyJ	both	47.65	9.3739204171	66.2112986599	29.0887013401
BXD48a/RwwJ	both	35.0666666667	9.3739204171	53.6279653266	16.5053680068
BXD62/RwwJ	both	60.6	9.3739204171	79.1612986599	42.0387013401
BXD68/RwwJ	both	60.425	11.4806609557	83.1578553401	37.6921446599
BXD77/RwwJ	both	61.5333333333	9.3739204171	80.0946319932	42.9720346734
BXD84/RwwJ	both	63.6333333333	9.3739204171	82.1946319932	45.0720346734
BXD98/RwwJ	both	69.3666666667	9.3739204171	87.9279653266	50.8053680068
C3H/HeJ	both	61.6333333333	9.3739204171	80.1946319932	43.0720346734
C57BL/10J	both	56.2708333333	8.768499643	73.6333383931	38.9083282736
C57BL/6J	both	76.6666666667	9.3739204171	95.2279653266	58.1053680068
C57BR/cdJ	both	54.6	9.3739204171	73.1612986599	36.0387013401
C57L/J	both	63.9083333333	10.4803616342	84.6604961104	43.1561705562
C58/J	both	34.0333333333	9.3739204171	52.5946319932	15.4720346734
CBA/J	both	55.7	9.3739204171	74.2612986599	37.1387013401
FVB/NJ	both	30.325	11.4806609557	53.0578553401	7.5921446599
I/LnJ	both	61.35	11.4806609557	84.0828553401	38.6171446599
KK/HlJ	both	75.1	9.3739204171	93.6612986599	56.5387013401
LP/J	both	72.4166666667	10.4803616342	93.1688294438	51.6645038896
MA/MyJ	both	61.0416666667	10.4803616342	81.7938294438	40.2895038896
NOD/ShiLtJ	both	37.775	10.4803616342	58.5271627771	17.0228372229
NZB/BlNJ	both	55.575	11.4806609557	78.3078553401	32.8421446599
NZW/LacJ	both	87.5	11.4806609557	110.2328553401	64.7671446599
PL/J	both	57.2333333333	10.4803616342	77.9854961104	36.4811705562
SM/J	both	60.5166666667	9.3739204171	79.0779653266	41.9553680068

INDIVIDUAL ANIMAL VALUES

Click here to view individual animal values

GWAS USING LINEAR MIXED MODELS