Project measure / variable:   Project1032   inactive_d3_cocaine

ID, description, units MPD:111504   inactive_d3_cocaine   number of inactive lever presses (intravenous self administration), cocaine   [n]  day 3  
cocaine study
Data set, strains Project1032   HMDP   63 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of inactive lever presses (intravenous self administration), cocaine day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested54 strains58 strains
Mean of the strain means8.9429   n 46.829   n
Median of the strain means4.4167   n 7.6667   n
SD of the strain means± 12.836 ± 149.8
Coefficient of variation (CV)1.4354 3.1997
Min–max range of strain means1.0   –   77.0   n 1.0   –   1076.0   n
Mean sample size per strain2.2   mice 2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 107979.4299 107979.4299 1.6794 0.1977
strain 32 2092931.3391 65404.1043 1.0172 0.4555
sex:strain 32 1319447.9796 41232.7494 0.6413 0.9251
Residuals 109 7008431.0 64297.5321


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 310.0 0.0   1   0.0 0.0 310.0, 310.0 1.76
A/J f 2.3333 2.3094   3 1.3333 0.9897 1.0, 5.0 -0.51
A/J m 50.5 51.62   2   36.5 1.0222 14.0, 87.0 0.02
AKR/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.62
AKR/J m 5.0 2.8284   2   2.0 0.5657 3.0, 7.0 -0.28
BALB/cByJ f 2.6667 1.1547   3 0.66667 0.433 2.0, 4.0 -0.49
BALB/cByJ m 33.0 0.0   1   0.0 0.0 33.0, 33.0 -0.09
BALB/cJ f 3.6667 2.5166   3 1.453 0.6863 1.0, 6.0 -0.41
BALB/cJ m 8.3333 4.6188   3 2.6667 0.5543 3.0, 11.0 -0.26
BPL/1J f 15.5 17.678   2   12.5 1.1405 3.0, 28.0 0.51
BPL/1J m 56.0 38.314   3 22.121 0.6842 30.0, 100.0 0.06
BTBR T+ Itpr3tf/J f 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.54
BTBR T+ Itpr3tf/J m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.29
BXD100/RwwJ f 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.54
BXD100/RwwJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.26
BXD11/TyJ m 185.0 0.0   1   0.0 0.0 185.0, 185.0 0.92
BXD15/TyJ f 19.5 17.678   2   12.5 0.9065 7.0, 32.0 0.82
BXD1/TyJ f 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.5
BXD1/TyJ m 2.3333 0.57735   3 0.33333 0.2474 2.0, 3.0 -0.3
BXD21/TyJ f 14.0 0.0   1   0.0 0.0 14.0, 14.0 0.39
BXD21/TyJ m 6.5 0.70711   2   0.5 0.1088 6.0, 7.0 -0.27
BXD2/TyJ f 13.5 2.1213   2   1.5 0.1571 12.0, 15.0 0.36
BXD2/TyJ m 137.3 210.2   3 121.4 1.5309 10.0, 380.0 0.6
BXD31/TyJ f 4.5 0.70711   2   0.5 0.1571 4.0, 5.0 -0.35
BXD31/TyJ m 21.0 17.436   3 10.066 0.8303 9.0, 41.0 -0.17
BXD32/TyJ f 1.0 0.0   3 0.0 0.0 1.0, 1.0 -0.62
BXD32/TyJ m 3.6667 2.0817   3 1.2019 0.5677 2.0, 6.0 -0.29
BXD34/TyJ f 11.5 9.1924   2   6.5 0.7993 5.0, 18.0 0.2
BXD38/TyJ f 7.5 3.5355   2   2.5 0.4714 5.0, 10.0 -0.11
BXD38/TyJ m 272.0 380.4   2   269.0 1.3986 3.0, 541.0 1.5
BXD39/TyJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.62
BXD39/TyJ m 5.0 6.9282   3 4.0 1.3856 1.0, 13.0 -0.28
BXD40/TyJ f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.58
BXD40/TyJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.3
BXD42/TyJ f 5.5 6.364   2   4.5 1.1571 1.0, 10.0 -0.27
BXD42/TyJ m 25.0 9.8995   2   7.0 0.396 18.0, 32.0 -0.15
BXD48a/RwwJ f 2.0 0.0   2   0.0 0.0 2.0, 2.0 -0.54
BXD48a/RwwJ m 29.0 47.634   3 27.502 1.6426 1.0, 84.0 -0.12
BXD50/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.54
BXD50/RwwJ m 7.5 4.9497   2   3.5 0.66 4.0, 11.0 -0.26
BXD55/RwwJ f 14.0 16.971   2   12.0 1.2122 2.0, 26.0 0.39
BXD55/RwwJ m 72.0 0.0   1   0.0 0.0 72.0, 72.0 0.17
BXD56/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.62
BXD60/RwwJ m 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.3
BXD61/RwwJ f 2.0 0.0   2   0.0 0.0 2.0, 2.0 -0.54
BXD61/RwwJ m 61.0 84.85   2   60.0 1.391 1.0, 121.0 0.09
BXD62/RwwJ f 2.0 0.0   3 0.0 0.0 2.0, 2.0 -0.54
BXD62/RwwJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.3
BXD63/RwwJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.29
BXD65/RwwJ f 28.5 9.1924   2   6.5 0.3225 22.0, 35.0 1.52
BXD65/RwwJ m 7.3333 2.5166   3 1.453 0.3432 5.0, 10.0 -0.26
BXD68/RwwJ m 12.0 14.142   2   10.0 1.1785 2.0, 22.0 -0.23
BXD69/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.62
BXD69/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.31
BXD70/RwwJ m 6.0 5.6569   2   4.0 0.9428 2.0, 10.0 -0.27
BXD71/RwwJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.39
BXD71/RwwJ m 8.5 10.607   2   7.5 1.2478 1.0, 16.0 -0.26
BXD73a/RwwJ f 23.0 0.0   1   0.0 0.0 23.0, 23.0 1.1
BXD73a/RwwJ m 27.0 0.0   1   0.0 0.0 27.0, 27.0 -0.13
BXD75/RwwJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.39
BXD75/RwwJ m 11.5 3.5355   2   2.5 0.3074 9.0, 14.0 -0.24
BXD77/RwwJ f 5.0 4.2426   2   3.0 0.8485 2.0, 8.0 -0.31
BXD77/RwwJ m 19.0 6.0828   3 3.5119 0.3201 15.0, 26.0 -0.19
BXD84/RwwJ f 4.3333 4.1633   3 2.4037 0.9608 1.0, 9.0 -0.36
BXD84/RwwJ m 1.6667 0.57735   3 0.33333 0.3464 1.0, 2.0 -0.3
BXD90/RwwJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.21
BXD98/RwwJ f 3.3333 3.2146   3 1.8559 0.9644 1.0, 7.0 -0.44
BXD98/RwwJ m 12.0 1.7321   3 1.0 0.1443 11.0, 14.0 -0.23
BXD99/RwwJ f 11.0 0.0   1   0.0 0.0 11.0, 11.0 0.16
C3HeB/FeJ f 5.6667 6.4291   3 3.7118 1.1345 1.0, 13.0 -0.26
C3HeB/FeJ m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.3
C3H/HeJ f 4.5 2.1213   2   1.5 0.4714 3.0, 6.0 -0.35
C3H/HeJ m 14.0 9.8995   2   7.0 0.7071 7.0, 21.0 -0.22
C57BL/10J f 17.0 24.269   3 14.012 1.4276 2.0, 45.0 0.63
C57BL/10J m 2.3333 1.1547   3 0.66667 0.4949 1.0, 3.0 -0.3
C57BL/6J f 14.0 16.971   2   12.0 1.2122 2.0, 26.0 0.39
C57BL/6J m 63.67 98.23   3 56.71 1.5429 3.0, 177.0 0.11
C57BLKS/J f 6.0 7.0711   2   5.0 1.1785 1.0, 11.0 -0.23
C57BLKS/J m 4.6667 3.2146   3 1.8559 0.6888 1.0, 7.0 -0.28
C57BR/cdJ f 13.0 15.716   3 9.0738 1.2089 2.0, 31.0 0.32
C57BR/cdJ m 7.6667 9.0738   3 5.2387 1.1835 1.0, 18.0 -0.26
C57L/J f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.07
C57L/J m 7.6667 5.6862   3 3.283 0.7417 3.0, 14.0 -0.26
C58/J f 7.6667 2.0817   3 1.2019 0.2715 6.0, 10.0 -0.1
C58/J m 5.6667 3.2146   3 1.8559 0.5673 2.0, 8.0 -0.27
CBA/J f 7.6667 8.9629   3 5.1747 1.1691 2.0, 18.0 -0.1
CBA/J m 1.3333 0.57735   3 0.33333 0.433 1.0, 2.0 -0.3
DBA/1J f 1.6667 0.57735   3 0.33333 0.3464 1.0, 2.0 -0.57
DBA/1J m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.3
DBA/2J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.31
FVB/NJ f 7.5 9.1924   2   6.5 1.2257 1.0, 14.0 -0.11
FVB/NJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.3
I/LnJ f 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.5
KK/HlJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.62
KK/HlJ m 20.0 24.269   3 14.012 1.2135 5.0, 48.0 -0.18
LP/J f 2.6667 2.0817   3 1.2019 0.7806 1.0, 5.0 -0.49
LP/J m 14.0 15.556   2   11.0 1.1112 3.0, 25.0 -0.22
MA/MyJ f 40.0 26.851   3 15.503 0.6713 11.0, 64.0 2.42
MA/MyJ m 8.6667 11.59   3 6.6916 1.3373 1.0, 22.0 -0.25
MRL/MpJ f 2.3333 2.3094   3 1.3333 0.9897 1.0, 5.0 -0.51
MRL/MpJ m 3.3333 3.2146   3 1.8559 0.9644 1.0, 7.0 -0.29
NOD/ShiLtJ f 77.0 63.24   3 36.51 0.8213 39.0, 150.0 5.3
NOD/ShiLtJ m 30.667 30.6   3 17.667 0.9978 13.0, 66.0 -0.11
NZB/BlNJ m 4.5 4.9497   2   3.5 1.0999 1.0, 8.0 -0.28
NZO/HlLtJ f 1.6667 1.1547   3 0.66667 0.6928 1.0, 3.0 -0.57
NZO/HlLtJ m 4.0 1.4142   2   1.0 0.3536 3.0, 5.0 -0.29
NZW/LacJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.54
NZW/LacJ m 3.5 0.70711   2   0.5 0.202 3.0, 4.0 -0.29
PL/J f 38.0 50.91   2   36.0 1.3398 2.0, 74.0 2.26
PL/J m 1076.0 1833.0   3 1058.0 1.7039 4.0, 3192.0 6.87
SM/J f 4.75 4.1932   4 2.0966 0.8828 2.0, 11.0 -0.33
SM/J m 6.75 8.9209   4 4.4605 1.3216 1.0, 20.0 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 2.3333333333 146.3984655089 292.4903325193 -287.8236658526
A/J m 50.5 179.3007698116 405.8682966514 -304.8682966514
BALB/cJ f 3.6666666667 146.3984655089 293.8236658526 -286.4903325193
BALB/cJ m 8.3333333333 146.3984655089 298.4903325193 -281.8236658526
BPL/1J f 15.5 179.3007698116 370.8682966514 -339.8682966514
BPL/1J m 56.0 146.3984655089 346.156999186 -234.156999186
BXD1/TyJ f 2.5 179.3007698116 357.8682966514 -352.8682966514
BXD1/TyJ m 2.3333333333 146.3984655089 292.4903325193 -287.8236658526
BXD2/TyJ f 13.5 179.3007698116 368.8682966514 -341.8682966514
BXD2/TyJ m 137.3333333333 146.3984655089 427.4903325193 -152.8236658526
BXD31/TyJ f 4.5 179.3007698116 359.8682966514 -350.8682966514
BXD31/TyJ m 21.0 146.3984655089 311.156999186 -269.156999186
BXD32/TyJ f 1.0 146.3984655089 291.156999186 -289.156999186
BXD32/TyJ m 3.6666666667 146.3984655089 293.8236658526 -286.4903325193
BXD38/TyJ f 7.5 179.3007698116 362.8682966514 -347.8682966514
BXD38/TyJ m 272.0 179.3007698116 627.3682966514 -83.3682966514
BXD39/TyJ f 1.0 179.3007698116 356.3682966514 -354.3682966514
BXD39/TyJ m 5.0 146.3984655089 295.156999186 -285.156999186
BXD42/TyJ f 5.5 179.3007698116 360.8682966514 -349.8682966514
BXD42/TyJ m 25.0 179.3007698116 380.3682966514 -330.3682966514
BXD48a/RwwJ f 2.0 179.3007698116 357.3682966514 -353.3682966514
BXD48a/RwwJ m 29.0 146.3984655089 319.156999186 -261.156999186
BXD61/RwwJ f 2.0 179.3007698116 357.3682966514 -353.3682966514
BXD61/RwwJ m 61.0 179.3007698116 416.3682966514 -294.3682966514
BXD65/RwwJ f 28.5 179.3007698116 383.8682966514 -326.8682966514
BXD65/RwwJ m 7.3333333333 146.3984655089 297.4903325193 -282.8236658526
BXD77/RwwJ f 5.0 179.3007698116 360.3682966514 -350.3682966514
BXD77/RwwJ m 19.0 146.3984655089 309.156999186 -271.156999186
BXD84/RwwJ f 4.3333333333 146.3984655089 294.4903325193 -285.8236658526
BXD84/RwwJ m 1.6666666667 146.3984655089 291.8236658526 -288.4903325193
BXD98/RwwJ f 3.3333333333 146.3984655089 293.4903325193 -286.8236658526
BXD98/RwwJ m 12.0 146.3984655089 302.156999186 -278.156999186
C3HeB/FeJ f 5.6666666667 146.3984655089 295.8236658526 -284.4903325193
C3HeB/FeJ m 1.5 179.3007698116 356.8682966514 -353.8682966514
C3H/HeJ f 4.5 179.3007698116 359.8682966514 -350.8682966514
C3H/HeJ m 14.0 179.3007698116 369.3682966514 -341.3682966514
C57BL/10J f 17.0 146.3984655089 307.156999186 -273.156999186
C57BL/10J m 2.3333333333 146.3984655089 292.4903325193 -287.8236658526
C57BL/6J f 14.0 179.3007698116 369.3682966514 -341.3682966514
C57BL/6J m 63.6666666667 146.3984655089 353.8236658526 -226.4903325193
C57BLKS/J f 6.0 179.3007698116 361.3682966514 -349.3682966514
C57BLKS/J m 4.6666666667 146.3984655089 294.8236658526 -285.4903325193
C57BR/cdJ f 13.0 146.3984655089 303.156999186 -277.156999186
C57BR/cdJ m 7.6666666667 146.3984655089 297.8236658526 -282.4903325193
C58/J f 7.6666666667 146.3984655089 297.8236658526 -282.4903325193
C58/J m 5.6666666667 146.3984655089 295.8236658526 -284.4903325193
CBA/J f 7.6666666667 146.3984655089 297.8236658526 -282.4903325193
CBA/J m 1.3333333333 146.3984655089 291.4903325193 -288.8236658526
DBA/1J f 1.6666666667 146.3984655089 291.8236658526 -288.4903325193
DBA/1J m 1.5 179.3007698116 356.8682966514 -353.8682966514
KK/HlJ f 1.0 179.3007698116 356.3682966514 -354.3682966514
KK/HlJ m 20.0 146.3984655089 310.156999186 -270.156999186
LP/J f 2.6666666667 146.3984655089 292.8236658526 -287.4903325193
LP/J m 14.0 179.3007698116 369.3682966514 -341.3682966514
MA/MyJ f 40.0 146.3984655089 330.156999186 -250.156999186
MA/MyJ m 8.6666666667 146.3984655089 298.8236658526 -281.4903325193
MRL/MpJ f 2.3333333333 146.3984655089 292.4903325193 -287.8236658526
MRL/MpJ m 3.3333333333 146.3984655089 293.4903325193 -286.8236658526
NOD/ShiLtJ f 77.0 146.3984655089 367.156999186 -213.156999186
NOD/ShiLtJ m 30.6666666667 146.3984655089 320.8236658526 -259.4903325193
NZO/HlLtJ f 1.6666666667 146.3984655089 291.8236658526 -288.4903325193
NZO/HlLtJ m 4.0 179.3007698116 359.3682966514 -351.3682966514
PL/J f 38.0 179.3007698116 393.3682966514 -317.3682966514
PL/J m 1075.6666666667 146.3984655089 1365.8236658526 785.5096674807
SM/J f 4.75 126.7847902058 256.0333323809 -246.5333323809
SM/J m 6.75 126.7847902058 258.0333323809 -244.5333323809


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 26.4166666667 115.7381492404 255.8059157835 -202.9725824502
BALB/cJ both 6.0 103.5193477167 211.1719817331 -199.1719817331
BPL/1J both 35.75 115.7381492404 265.1392491168 -193.6392491168
BXD1/TyJ both 2.4166666667 115.7381492404 231.8059157835 -226.9725824502
BXD2/TyJ both 75.4166666667 115.7381492404 304.8059157835 -153.9725824502
BXD31/TyJ both 12.75 115.7381492404 242.1392491168 -216.6392491168
BXD32/TyJ both 2.3333333333 103.5193477167 207.5053150665 -202.8386483998
BXD38/TyJ both 139.75 126.7847902058 391.0333323809 -111.5333323809
BXD39/TyJ both 3.0 115.7381492404 232.3892491168 -226.3892491168
BXD42/TyJ both 15.25 126.7847902058 266.5333323809 -236.0333323809
BXD48a/RwwJ both 15.5 115.7381492404 244.8892491168 -213.8892491168
BXD61/RwwJ both 31.5 126.7847902058 282.7833323809 -219.7833323809
BXD65/RwwJ both 17.9166666667 115.7381492404 247.3059157835 -211.4725824502
BXD77/RwwJ both 12.0 115.7381492404 241.3892491168 -217.3892491168
BXD84/RwwJ both 3.0 103.5193477167 208.1719817331 -202.1719817331
BXD98/RwwJ both 7.6666666667 103.5193477167 212.8386483998 -197.5053150665
C3HeB/FeJ both 3.5833333333 115.7381492404 232.9725824502 -225.8059157835
C3H/HeJ both 9.25 126.7847902058 260.5333323809 -242.0333323809
C57BL/10J both 9.6666666667 103.5193477167 214.8386483998 -195.5053150665
C57BL/6J both 38.8333333333 115.7381492404 268.2225824502 -190.5559157835
C57BLKS/J both 5.3333333333 115.7381492404 234.7225824502 -224.0559157835
C57BR/cdJ both 10.3333333333 103.5193477167 215.5053150665 -194.8386483998
C58/J both 6.6666666667 103.5193477167 211.8386483998 -198.5053150665
CBA/J both 4.5 103.5193477167 209.6719817331 -200.6719817331
DBA/1J both 1.5833333333 115.7381492404 230.9725824502 -227.8059157835
KK/HlJ both 10.5 115.7381492404 239.8892491168 -218.8892491168
LP/J both 8.3333333333 115.7381492404 237.7225824502 -221.0559157835
MA/MyJ both 24.3333333333 103.5193477167 229.5053150665 -180.8386483998
MRL/MpJ both 2.8333333333 103.5193477167 208.0053150665 -202.3386483998
NOD/ShiLtJ both 53.8333333333 103.5193477167 259.0053150665 -151.3386483998
NZO/HlLtJ both 2.8333333333 115.7381492404 232.2225824502 -226.5559157835
PL/J both 556.8333333333 115.7381492404 786.2225824502 327.4440842165
SM/J both 5.75 89.6503849058 183.4341483257 -171.9341483257




  GWAS USING LINEAR MIXED MODELS