Project measure / variable:   Project1032   active_pct_d4_cocaine

ID, description, units MPD:111453   active_pct_d4_cocaine   percentage of lever presses that are active (intravenous self administration), cocaine   [%]  day 4  
cocaine study
Data set, strains Project1032   HMDP   64 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


  •   Or, add this measure to your collection.
       
  •     no folder
  •     put it in new folder  

  STRAIN COMPARISON PLOT
Dimensions Width:   px    Height:   px
Download Plot   
Visualization Options

Project1032 - percentage of lever presses that are active (intravenous self administration), cocaine day 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested58 strains61 strains
Mean of the strain means79.41   % 73.83   %
Median of the strain means81.97   % 78.8   %
SD of the strain means± 16.564 ± 19.929
Coefficient of variation (CV)0.2086 0.2699
Min–max range of strain means39.6   –   100.0   % 16.7   –   100.0   %
Mean sample size per strain2.1   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 239.5734 239.5734 0.4291 0.5137
strain 34 15180.8246 446.4948 0.7997 0.7705
sex:strain 34 27113.4715 797.455 1.4284 0.0838
Residuals 117 65320.7858 558.2973


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 96.55 4.879   2   3.45 0.0505 93.1, 100.0 1.14
129X1/SvJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.24
A/J f 89.2 6.643   3 3.8354 0.0745 81.6, 93.9 0.59
A/J m 53.45 65.83   2   46.55 1.2316 6.9, 100.0 -1.02
AKR/J f 63.5 11.172   2   7.9 0.1759 55.6, 71.4 -0.96
AKR/J m 91.8 0.14142   2   0.1 0.0015 91.7, 91.9 0.9
BALB/cByJ f 72.8 34.231   3 19.763 0.4702 33.3, 93.8 -0.4
BALB/cByJ m 62.37 32.398   3 18.705 0.5195 25.0, 82.6 -0.57
BALB/cJ f 78.55 20.577   2   14.55 0.262 64.0, 93.1 -0.05
BALB/cJ m 48.7 13.471   3 7.7777 0.2766 33.3, 58.3 -1.26
BPL/1J f 70.47 29.066   3 16.781 0.4125 39.4, 97.0 -0.54
BPL/1J m 37.533 29.313   3 16.924 0.781 15.1, 70.7 -1.82
BTBR T+ Itpr3tf/J f 80.0 28.284   2   20.0 0.3536 60.0, 100.0 0.04
BTBR T+ Itpr3tf/J m 90.0 14.142   2   10.0 0.1571 80.0, 100.0 0.81
BXD100/RwwJ f 100.0 0.0   2   0.0 0.0 100.0, 100.0 1.24
BXD100/RwwJ m 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.31
BXD11/TyJ f 100.0 0.0   2   0.0 0.0 100.0, 100.0 1.24
BXD11/TyJ m 53.2 66.19   2   46.8 1.2441 6.4, 100.0 -1.04
BXD15/TyJ f 90.67 13.014   3 7.5138 0.1435 75.8, 100.0 0.68
BXD15/TyJ m 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.31
BXD1/TyJ f 75.0 35.355   2   25.0 0.4714 50.0, 100.0 -0.27
BXD1/TyJ m 90.1 16.374   3 9.4536 0.1817 71.2, 100.0 0.82
BXD21/TyJ f 76.0 0.0   1   0.0 0.0 76.0, 76.0 -0.21
BXD21/TyJ m 75.75 32.88   2   23.25 0.4341 52.5, 99.0 0.1
BXD2/TyJ f 71.47 22.272   3 12.859 0.3116 45.8, 85.7 -0.48
BXD2/TyJ m 57.97 43.863   3 25.324 0.7567 8.2, 91.0 -0.8
BXD31/TyJ f 84.57 17.452   3 10.076 0.2064 64.5, 96.2 0.31
BXD31/TyJ m 60.4 24.456   4 12.228 0.4049 40.0, 94.9 -0.67
BXD32/TyJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.24
BXD32/TyJ m 62.8 32.724   3 18.893 0.5211 33.3, 98.0 -0.55
BXD34/TyJ f 75.0 3.9598   2   2.8 0.0528 72.2, 77.8 -0.27
BXD38/TyJ f 75.4 17.112   2   12.1 0.2269 63.3, 87.5 -0.24
BXD38/TyJ m 68.13 46.708   3 26.967 0.6855 14.3, 97.9 -0.29
BXD39/TyJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.24
BXD39/TyJ m 55.57 9.6417   3 5.5667 0.1735 50.0, 66.7 -0.92
BXD40/TyJ f 50.0 0.0   1   0.0 0.0 50.0, 50.0 -1.78
BXD40/TyJ m 65.65 45.75   2   32.35 0.6969 33.3, 98.0 -0.41
BXD42/TyJ f 47.95 47.871   2   33.85 0.9984 14.1, 81.8 -1.9
BXD42/TyJ m 89.57 16.12   3 9.307 0.18 71.0, 100.0 0.79
BXD48a/RwwJ f 90.0 14.142   2   10.0 0.1571 80.0, 100.0 0.64
BXD48a/RwwJ m 74.13 25.63   3 14.797 0.3457 44.8, 92.2 0.02
BXD50/RwwJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.24
BXD50/RwwJ m 63.55 33.305   2   23.55 0.5241 40.0, 87.1 -0.52
BXD55/RwwJ f 86.35 19.304   2   13.65 0.2236 72.7, 100.0 0.42
BXD55/RwwJ m 37.0 0.0   1   0.0 0.0 37.0, 37.0 -1.85
BXD60/RwwJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.24
BXD60/RwwJ m 22.25 21.567   2   15.25 0.9693 7.0, 37.5 -2.59
BXD61/RwwJ f 83.63 23.187   3 13.387 0.2772 57.1, 100.0 0.25
BXD61/RwwJ m 82.6 0.0   1   0.0 0.0 82.6, 82.6 0.44
BXD62/RwwJ f 61.3 10.75   3 6.2067 0.1754 50.0, 71.4 -1.09
BXD62/RwwJ m 99.05 1.3435   2   0.95 0.0136 98.1, 100.0 1.27
BXD63/RwwJ m 16.7 0.0   1   0.0 0.0 16.7, 16.7 -2.87
BXD65/RwwJ f 87.43 13.177   3 7.6075 0.1507 72.9, 98.6 0.48
BXD65/RwwJ m 84.47 21.994   3 12.698 0.2604 59.3, 100.0 0.53
BXD68/RwwJ m 89.55 0.6364   2   0.45 0.0071 89.1, 90.0 0.79
BXD69/RwwJ f 76.15 24.254   2   17.15 0.3185 59.0, 93.3 -0.2
BXD70/RwwJ m 96.6 0.0   1   0.0 0.0 96.6, 96.6 1.14
BXD71/RwwJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.24
BXD71/RwwJ m 70.6 6.2225   2   4.4 0.0881 66.2, 75.0 -0.16
BXD73a/RwwJ f 62.25 45.467   2   32.15 0.7304 30.1, 94.4 -1.04
BXD73a/RwwJ m 78.8 0.0   1   0.0 0.0 78.8, 78.8 0.25
BXD75/RwwJ f 94.3 0.0   1   0.0 0.0 94.3, 94.3 0.9
BXD75/RwwJ m 92.3 2.2627   2   1.6 0.0245 90.7, 93.9 0.93
BXD77/RwwJ f 64.25 34.295   2   24.25 0.5338 40.0, 88.5 -0.92
BXD77/RwwJ m 81.07 8.9673   3 5.1773 0.1106 71.0, 88.2 0.36
BXD84/RwwJ f 87.9 14.409   3 8.3189 0.1639 71.4, 98.0 0.51
BXD84/RwwJ m 83.6 22.538   3 13.012 0.2696 57.9, 100.0 0.49
BXD90/RwwJ m 86.25 4.1719   2   2.95 0.0484 83.3, 89.2 0.62
BXD98/RwwJ f 80.6 17.395   2   12.3 0.2158 68.3, 92.9 0.07
BXD98/RwwJ m 82.5 8.2164   3 4.7438 0.0996 75.4, 91.5 0.44
BXD99/RwwJ m 95.7 0.0   1   0.0 0.0 95.7, 95.7 1.1
C3HeB/FeJ f 39.6 20.648   2   14.6 0.5214 25.0, 54.2 -2.4
C3HeB/FeJ m 95.65 6.1518   2   4.35 0.0643 91.3, 100.0 1.09
C3H/HeJ f 60.0 56.57   2   40.0 0.9428 20.0, 100.0 -1.17
C3H/HeJ m 74.6 22.515   3 12.999 0.3018 57.1, 100.0 0.04
C57BL/10J f 78.53 21.55   3 12.442 0.2744 56.9, 100.0 -0.05
C57BL/10J m 93.6 11.085   3 6.4 0.1184 80.8, 100.0 0.99
C57BL/6J f 86.15 19.587   2   13.85 0.2274 72.3, 100.0 0.41
C57BL/6J m 84.42 12.121   4 6.0603 0.1436 70.5, 100.0 0.53
C57BLKS/J f 94.45 4.7376   2   3.35 0.0502 91.1, 97.8 0.91
C57BLKS/J m 88.07 12.538   3 7.2391 0.1424 75.0, 100.0 0.71
C57BR/cdJ f 80.5 8.9034   3 5.1404 0.1106 70.8, 88.3 0.07
C57BR/cdJ m 82.7 13.097   3 7.5613 0.1584 68.3, 93.9 0.45
C57L/J f 92.3 0.0   1   0.0 0.0 92.3, 92.3 0.78
C57L/J m 82.3 15.043   3 8.685 0.1828 65.0, 92.3 0.43
C58/J f 84.73 12.664   3 7.3115 0.1495 71.4, 96.6 0.32
C58/J m 66.63 8.75   3 5.0518 0.1313 56.7, 73.2 -0.36
CBA/J f 42.8 30.481   3 17.598 0.7122 18.2, 76.9 -2.21
CBA/J m 78.43 10.577   3 6.1064 0.1348 70.0, 90.3 0.23
DBA/1J f 80.35 7.566   2   5.35 0.0942 75.0, 85.7 0.06
DBA/1J m 66.7 0.0   1   0.0 0.0 66.7, 66.7 -0.36
DBA/2J f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.24
DBA/2J m 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.31
FVB/NJ f 74.57 25.011   3 14.44 0.3354 50.0, 100.0 -0.29
FVB/NJ m 66.7 0.0   2   0.0 0.0 66.7, 66.7 -0.36
I/LnJ f 84.25 0.49497   2   0.35 0.0059 83.9, 84.6 0.29
I/LnJ m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -2.7
KK/HlJ f 91.7 0.0   1   0.0 0.0 91.7, 91.7 0.74
KK/HlJ m 79.87 17.759   3 10.253 0.2224 60.0, 94.2 0.3
LP/J f 99.65 0.49497   2   0.35 0.005 99.3, 100.0 1.22
LP/J m 84.65 6.0104   2   4.25 0.071 80.4, 88.9 0.54
MA/MyJ f 40.9 8.1431   3 4.7014 0.1991 34.3, 50.0 -2.33
MA/MyJ m 92.5 2.7785   3 1.6042 0.03 90.7, 95.7 0.94
MRL/MpJ f 85.3 20.789   2   14.7 0.2437 70.6, 100.0 0.36
MRL/MpJ m 73.07 22.163   3 12.796 0.3033 50.0, 94.2 -0.04
NOD/ShiLtJ f 48.133 18.252   3 10.538 0.3792 27.8, 63.1 -1.89
NOD/ShiLtJ m 80.3 22.26   3 12.852 0.2772 54.7, 95.1 0.32
NZB/BlNJ f 66.65 47.164   2   33.35 0.7076 33.3, 100.0 -0.77
NZB/BlNJ m 70.97 18.473   3 10.666 0.2603 55.0, 91.2 -0.14
NZO/HlLtJ f 90.67 6.5164   3 3.7622 0.0719 83.9, 96.9 0.68
NZO/HlLtJ m 67.53 32.058   3 18.509 0.4747 35.9, 100.0 -0.32
NZW/LacJ f 63.7 42.992   2   30.4 0.6749 33.3, 94.1 -0.95
NZW/LacJ m 62.5 17.678   2   12.5 0.2828 50.0, 75.0 -0.57
PL/J f 95.2 0.0   1   0.0 0.0 95.2, 95.2 0.95
PL/J m 59.87 34.156   3 19.72 0.5705 31.3, 97.7 -0.7
SJL/J f 83.33 28.868   3 16.667 0.3464 50.0, 100.0 0.24
SJL/J m 50.0 0.0   1   0.0 0.0 50.0, 50.0 -1.2
SM/J f 67.75 8.8123   4 4.4062 0.1301 57.1, 78.6 -0.7
SM/J m 86.2 25.639   4 12.82 0.2974 47.8, 100.0 0.62


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 89.2 13.6418145765 116.2168989196 62.1831010804
A/J m 53.45 16.707742439 86.5388083927 20.3611916073
AKR/J f 63.5 16.707742439 96.5888083927 30.4111916073
AKR/J m 91.8 16.707742439 124.8888083927 58.7111916073
BALB/cByJ f 72.8 13.6418145765 99.8168989196 45.7831010804
BALB/cByJ m 62.3666666667 13.6418145765 89.3835655863 35.349767747
BALB/cJ f 78.55 16.707742439 111.6388083927 45.4611916073
BALB/cJ m 48.7 13.6418145765 75.7168989196 21.6831010804
BPL/1J f 70.4666666667 13.6418145765 97.4835655863 43.449767747
BPL/1J m 37.5333333333 13.6418145765 64.5502322529 10.5164344137
BTBR T+ Itpr3tf/J f 80.0 16.707742439 113.0888083927 46.9111916073
BTBR T+ Itpr3tf/J m 90.0 16.707742439 123.0888083927 56.9111916073
BXD11/TyJ f 100.0 16.707742439 133.0888083927 66.9111916073
BXD11/TyJ m 53.2 16.707742439 86.2888083927 20.1111916073
BXD1/TyJ f 75.0 16.707742439 108.0888083927 41.9111916073
BXD1/TyJ m 90.1 13.6418145765 117.1168989196 63.0831010804
BXD2/TyJ f 71.4666666667 13.6418145765 98.4835655863 44.449767747
BXD2/TyJ m 57.9666666667 13.6418145765 84.9835655863 30.949767747
BXD31/TyJ f 84.5666666667 13.6418145765 111.5835655863 57.549767747
BXD31/TyJ m 60.4 11.8141579769 83.7973207959 37.0026792041
BXD38/TyJ f 75.4 16.707742439 108.4888083927 42.3111916073
BXD38/TyJ m 68.1333333333 13.6418145765 95.1502322529 41.1164344137
BXD42/TyJ f 47.95 16.707742439 81.0388083927 14.8611916073
BXD42/TyJ m 89.5666666667 13.6418145765 116.5835655863 62.549767747
BXD48a/RwwJ f 90.0 16.707742439 123.0888083927 56.9111916073
BXD48a/RwwJ m 74.1333333333 13.6418145765 101.1502322529 47.1164344137
BXD62/RwwJ f 61.3 13.6418145765 88.3168989196 34.2831010804
BXD62/RwwJ m 99.05 16.707742439 132.1388083927 65.9611916073
BXD65/RwwJ f 87.4333333333 13.6418145765 114.4502322529 60.4164344137
BXD65/RwwJ m 84.4666666667 13.6418145765 111.4835655863 57.449767747
BXD77/RwwJ f 64.25 16.707742439 97.3388083927 31.1611916073
BXD77/RwwJ m 81.0666666667 13.6418145765 108.0835655863 54.049767747
BXD84/RwwJ f 87.9 13.6418145765 114.9168989196 60.8831010804
BXD84/RwwJ m 83.6 13.6418145765 110.6168989196 56.5831010804
BXD98/RwwJ f 80.6 16.707742439 113.6888083927 47.5111916073
BXD98/RwwJ m 82.5 13.6418145765 109.5168989196 55.4831010804
C3HeB/FeJ f 39.6 16.707742439 72.6888083927 6.5111916073
C3HeB/FeJ m 95.65 16.707742439 128.7388083927 62.5611916073
C3H/HeJ f 60.0 16.707742439 93.0888083927 26.9111916073
C3H/HeJ m 74.6 13.6418145765 101.6168989196 47.5831010804
C57BL/10J f 78.5333333333 13.6418145765 105.5502322529 51.5164344137
C57BL/10J m 93.6 13.6418145765 120.6168989196 66.5831010804
C57BL/6J f 86.15 16.707742439 119.2388083927 53.0611916073
C57BL/6J m 84.425 11.8141579769 107.8223207959 61.0276792041
C57BLKS/J f 94.45 16.707742439 127.5388083927 61.3611916073
C57BLKS/J m 88.0666666667 13.6418145765 115.0835655863 61.049767747
C57BR/cdJ f 80.5 13.6418145765 107.5168989196 53.4831010804
C57BR/cdJ m 82.7 13.6418145765 109.7168989196 55.6831010804
C58/J f 84.7333333333 13.6418145765 111.7502322529 57.7164344137
C58/J m 66.6333333333 13.6418145765 93.6502322529 39.6164344137
CBA/J f 42.8 13.6418145765 69.8168989196 15.7831010804
CBA/J m 78.4333333333 13.6418145765 105.4502322529 51.4164344137
FVB/NJ f 74.5666666667 13.6418145765 101.5835655863 47.549767747
FVB/NJ m 66.7 16.707742439 99.7888083927 33.6111916073
LP/J f 99.65 16.707742439 132.7388083927 66.5611916073
LP/J m 84.65 16.707742439 117.7388083927 51.5611916073
MA/MyJ f 40.9 13.6418145765 67.9168989196 13.8831010804
MA/MyJ m 92.5 13.6418145765 119.5168989196 65.4831010804
MRL/MpJ f 85.3 16.707742439 118.3888083927 52.2111916073
MRL/MpJ m 73.0666666667 13.6418145765 100.0835655863 46.049767747
NOD/ShiLtJ f 48.1333333333 13.6418145765 75.1502322529 21.1164344137
NOD/ShiLtJ m 80.3 13.6418145765 107.3168989196 53.2831010804
NZB/BlNJ f 66.65 16.707742439 99.7388083927 33.5611916073
NZB/BlNJ m 70.9666666667 13.6418145765 97.9835655863 43.949767747
NZO/HlLtJ f 90.6666666667 13.6418145765 117.6835655863 63.6497677471
NZO/HlLtJ m 67.5333333333 13.6418145765 94.550232253 40.5164344137
NZW/LacJ f 63.7 16.707742439 96.7888083927 30.6111916073
NZW/LacJ m 62.5 16.707742439 95.5888083927 29.4111916073
SM/J f 67.75 11.8141579769 91.1473207959 44.3526792041
SM/J m 86.2 11.8141579769 109.5973207959 62.8026792041


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 71.325 10.7848013698 92.6837339751 49.9662660249
AKR/J both 77.65 11.8141579769 101.0473207959 54.2526792041
BALB/cByJ both 67.5833333333 9.6462195947 86.687165766 48.4795009006
BALB/cJ both 63.625 10.7848013698 84.9837339751 42.2662660249
BPL/1J both 54.0 9.6462195947 73.1038324327 34.8961675673
BTBR T+ Itpr3tf/J both 85.0 11.8141579769 108.3973207959 61.6026792041
BXD11/TyJ both 76.6 11.8141579769 99.9973207959 53.2026792041
BXD1/TyJ both 82.55 10.7848013698 103.9087339751 61.1912660249
BXD2/TyJ both 64.7166666667 9.6462195947 83.8204990994 45.612834234
BXD31/TyJ both 72.4833333333 9.0232122002 90.3533322677 54.613334399
BXD38/TyJ both 71.7666666667 10.7848013698 93.1254006418 50.4079326915
BXD42/TyJ both 68.7583333333 10.7848013698 90.1170673085 47.3995993582
BXD48a/RwwJ both 82.0666666667 10.7848013698 103.4254006418 60.7079326915
BXD62/RwwJ both 80.175 10.7848013698 101.5337339751 58.8162660249
BXD65/RwwJ both 85.95 9.6462195947 105.0538324327 66.8461675673
BXD77/RwwJ both 72.6583333333 10.7848013698 94.0170673085 51.2995993582
BXD84/RwwJ both 85.75 9.6462195947 104.8538324327 66.6461675673
BXD98/RwwJ both 81.55 10.7848013698 102.9087339751 60.1912660249
C3HeB/FeJ both 67.625 11.8141579769 91.0223207959 44.2276792041
C3H/HeJ both 67.3 10.7848013698 88.6587339751 45.9412660249
C57BL/10J both 86.0666666667 9.6462195947 105.1704990994 66.962834234
C57BL/6J both 85.2875 10.2313609323 105.5501741897 65.0248258103
C57BLKS/J both 91.2583333333 10.7848013698 112.6170673085 69.8995993582
C57BR/cdJ both 81.6 9.6462195947 100.7038324327 62.4961675673
C58/J both 75.6833333333 9.6462195947 94.787165766 56.5795009006
CBA/J both 60.6166666667 9.6462195947 79.7204990994 41.512834234
FVB/NJ both 70.6333333333 10.7848013698 91.9920673085 49.2745993582
LP/J both 92.15 11.8141579769 115.5473207959 68.7526792041
MA/MyJ both 66.7 9.6462195947 85.8038324327 47.5961675673
MRL/MpJ both 79.1833333333 10.7848013698 100.5420673085 57.8245993582
NOD/ShiLtJ both 64.2166666667 9.6462195947 83.3204990994 45.112834234
NZB/BlNJ both 68.8083333333 10.7848013698 90.1670673085 47.4495993582
NZO/HlLtJ both 79.1 9.6462195947 98.2038324327 59.9961675673
NZW/LacJ both 63.1 11.8141579769 86.4973207959 39.7026792041
SM/J both 76.975 8.3538712195 93.5194041964 60.4305958036




  GWAS USING LINEAR MIXED MODELS