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Project measure / variable:   Project1032   inactive_d8_cocaine

ID, description, units MPD:111509   inactive_d8_cocaine   number of inactive lever presses (intravenous self administration), cocaine   [n]  day 8  
cocaine study
Data set, strains Project1032   HMDP   64 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


  STRAIN COMPARISON PLOT
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Project1032 - number of inactive lever presses (intravenous self administration), cocaine day 8



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested59 strains57 strains
Mean of the strain means20.378   n 26.735   n
Median of the strain means7.6667   n 6.0   n
SD of the strain means± 32.243 ± 70.49
Coefficient of variation (CV)1.5822 2.6366
Min–max range of strain means1.0   –   128.0   n 1.0   –   354.0   n
Mean sample size per strain1.8   mice 2.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17466.2164 17466.2164 0.9324 0.3373
strain 23 371611.9676 16157.0421 0.8625 0.6445
sex:strain 23 330353.6412 14363.2018 0.7668 0.7595
Residuals 75 1404879.1667 18731.7222


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.6
A/J f 9.6667 15.011   3 8.6667 1.5529 1.0, 27.0 -0.33
A/J m 12.0 9.8995   2   7.0 0.825 5.0, 19.0 -0.21
AKR/J f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.51
AKR/J m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.35
BALB/cByJ f 8.0 5.2915   3 3.0551 0.6614 4.0, 14.0 -0.38
BALB/cByJ m 11.0 1.4142   2   1.0 0.1286 10.0, 12.0 -0.22
BALB/cJ f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.59
BALB/cJ m 8.0 9.6437   3 5.5678 1.2055 1.0, 19.0 -0.27
BPL/1J f 128.0 22.627   2   16.0 0.1768 112.0, 144.0 3.34
BPL/1J m 23.333 27.791   3 16.045 1.191 3.0, 55.0 -0.05
BTBR T+ Itpr3tf/J f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.57
BTBR T+ Itpr3tf/J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.37
BXD100/RwwJ f 6.0 5.6569   2   4.0 0.9428 2.0, 10.0 -0.45
BXD100/RwwJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.29
BXD11/TyJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.6
BXD11/TyJ m 183.5 258.1   2   182.5 1.4065 1.0, 366.0 2.22
BXD15/TyJ f 37.0 0.0   1   0.0 0.0 37.0, 37.0 0.52
BXD1/TyJ m 5.0 4.2426   2   3.0 0.8485 2.0, 8.0 -0.31
BXD21/TyJ f 23.0 0.0   1   0.0 0.0 23.0, 23.0 0.08
BXD21/TyJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.31
BXD28/TyJ f 112.0 0.0   1   0.0 0.0 112.0, 112.0 2.84
BXD2/TyJ f 48.333 37.434   3 21.613 0.7745 21.0, 91.0 0.87
BXD2/TyJ m 73.5 99.7   2   70.5 1.3565 3.0, 144.0 0.66
BXD31/TyJ f 10.5 13.435   2   9.5 1.2795 1.0, 20.0 -0.31
BXD31/TyJ m 7.0 5.2281   4 2.6141 0.7469 2.0, 12.0 -0.28
BXD32/TyJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.54
BXD32/TyJ m 5.0 3.0   3 1.7321 0.6 2.0, 8.0 -0.31
BXD34/TyJ f 7.5 2.1213   2   1.5 0.2828 6.0, 9.0 -0.4
BXD34/TyJ m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.32
BXD38/TyJ f 11.333 4.0415   3 2.3333 0.3566 7.0, 15.0 -0.28
BXD38/TyJ m 8.6667 11.547   3 6.6667 1.3323 2.0, 22.0 -0.26
BXD39/TyJ f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.32
BXD39/TyJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.29
BXD40/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.6
BXD40/TyJ m 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.37
BXD42/TyJ f 126.0 0.0   1   0.0 0.0 126.0, 126.0 3.28
BXD42/TyJ m 4.0 2.8284   2   2.0 0.7071 2.0, 6.0 -0.32
BXD48a/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.57
BXD48a/RwwJ m 14.667 21.939   3 12.667 1.4959 2.0, 40.0 -0.17
BXD50/RwwJ f 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.2
BXD50/RwwJ m 12.5 9.1924   2   6.5 0.7354 6.0, 19.0 -0.2
BXD55/RwwJ f 5.0 5.6569   2   4.0 1.1314 1.0, 9.0 -0.48
BXD55/RwwJ m 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.27
BXD56/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.37
BXD60/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.6
BXD60/RwwJ m 3.0 1.4142   2   1.0 0.4714 2.0, 4.0 -0.34
BXD61/RwwJ f 70.5 95.46   2   67.5 1.354 3.0, 138.0 1.55
BXD62/RwwJ f 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.14
BXD62/RwwJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.28
BXD63/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.6
BXD63/RwwJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.29
BXD65/RwwJ f 54.5 34.648   2   24.5 0.6357 30.0, 79.0 1.06
BXD65/RwwJ m 4.5 0.70711   2   0.5 0.1571 4.0, 5.0 -0.32
BXD68/RwwJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 0.7
BXD68/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.37
BXD69/RwwJ f 30.5 40.305   2   28.5 1.3215 2.0, 59.0 0.31
BXD70/RwwJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.51
BXD70/RwwJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.35
BXD71/RwwJ f 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.01
BXD71/RwwJ m 23.0 26.87   2   19.0 1.1683 4.0, 42.0 -0.05
BXD73a/RwwJ f 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.14
BXD73a/RwwJ m 213.0 0.0   1   0.0 0.0 213.0, 213.0 2.64
BXD75/RwwJ f 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.26
BXD75/RwwJ m 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.21
BXD77/RwwJ f 6.6667 7.2342   3 4.1767 1.0851 2.0, 15.0 -0.43
BXD77/RwwJ m 9.3333 14.434   3 8.3333 1.5465 1.0, 26.0 -0.25
BXD84/RwwJ f 16.5 21.92   2   15.5 1.3285 1.0, 32.0 -0.12
BXD84/RwwJ m 11.667 17.616   3 10.171 1.51 1.0, 32.0 -0.21
BXD90/RwwJ m 3.0 2.8284   2   2.0 0.9428 1.0, 5.0 -0.34
BXD98/RwwJ f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.59
BXD98/RwwJ m 3.0 1.4142   2   1.0 0.4714 2.0, 4.0 -0.34
BXD99/RwwJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.38
BXD99/RwwJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.28
C3HeB/FeJ f 6.0 4.3589   3 2.5166 0.7265 1.0, 9.0 -0.45
C3HeB/FeJ m 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.33
C3H/HeJ f 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.52
C3H/HeJ m 5.0 5.6569   2   4.0 1.1314 1.0, 9.0 -0.31
C57BL/10J f 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.55
C57BL/10J m 3.5 3.5355   2   2.5 1.0102 1.0, 6.0 -0.33
C57BL/6J f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.38
C57BL/6J m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.36
C57BLKS/J f 4.5 0.70711   2   0.5 0.1571 4.0, 5.0 -0.49
C57BLKS/J m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.35
C57BR/cdJ f 7.6667 6.4291   3 3.7118 0.8386 3.0, 15.0 -0.39
C57BR/cdJ m 6.5 7.7782   2   5.5 1.1966 1.0, 12.0 -0.29
C57L/J f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.57
C57L/J m 16.5 13.435   2   9.5 0.8142 7.0, 26.0 -0.15
C58/J f 5.3333 3.0551   3 1.7638 0.5728 2.0, 8.0 -0.47
C58/J m 4.0 4.3589   3 2.5166 1.0897 1.0, 9.0 -0.32
CBA/J f 14.0 16.462   3 9.5044 1.1759 4.0, 33.0 -0.2
CBA/J m 3.0 1.4142   2   1.0 0.4714 2.0, 4.0 -0.34
DBA/1J f 3.0 1.7321   3 1.0 0.5774 1.0, 4.0 -0.54
DBA/1J m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.32
DBA/2J f 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.57
FVB/NJ f 34.0 0.0   1   0.0 0.0 34.0, 34.0 0.42
FVB/NJ m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.36
I/LnJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.6
I/LnJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.27
KK/HlJ f 3.0 1.4142   2   1.0 0.4714 2.0, 4.0 -0.54
KK/HlJ m 18.0 8.544   3 4.9329 0.4747 10.0, 27.0 -0.12
MA/MyJ f 104.0 144.1   3 83.19 1.3854 3.0, 269.0 2.59
MA/MyJ m 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.37
MRL/MpJ f 3.0 2.8284   2   2.0 0.9428 1.0, 5.0 -0.54
MRL/MpJ m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.32
NOD/ShiLtJ f 100.3 142.7   3 82.37 1.4219 14.0, 265.0 2.48
NOD/ShiLtJ m 8.3333 11.015   3 6.3596 1.3218 1.0, 21.0 -0.26
NZB/BlNJ m 1.6667 1.1547   3 0.66667 0.6928 1.0, 3.0 -0.36
NZO/HlLtJ f 3.0 2.8284   2   2.0 0.9428 1.0, 5.0 -0.54
NZO/HlLtJ m 321.7 555.4   3 320.7 1.7267 1.0, 963.0 4.18
NZW/LacJ m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.36
PL/J f 8.0 8.4853   2   6.0 1.0607 2.0, 14.0 -0.38
PL/J m 354.0 555.6   3 320.8 1.5694 11.0, 995.0 4.64
SJL/J f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.59
SM/J f 13.0 16.432   4 8.2158 1.264 1.0, 37.0 -0.23
SM/J m 9.0 14.674   4 7.3371 1.6305 1.0, 31.0 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 9.6666666667 79.0183991701 167.0793898593 -147.7460565259
A/J m 12.0 96.7773791292 204.7904254219 -180.7904254219
BALB/cByJ f 8.0 79.0183991701 165.4127231926 -149.4127231926
BALB/cByJ m 11.0 96.7773791292 203.7904254219 -181.7904254219
BALB/cJ f 1.5 96.7773791292 194.2904254219 -191.2904254219
BALB/cJ m 8.0 79.0183991701 165.4127231926 -149.4127231926
BPL/1J f 128.0 96.7773791292 320.7904254219 -64.7904254219
BPL/1J m 23.3333333333 79.0183991701 180.7460565259 -134.0793898593
BXD11/TyJ f 1.0 96.7773791292 193.7904254219 -191.7904254219
BXD11/TyJ m 183.5 96.7773791292 376.2904254219 -9.2904254219
BXD2/TyJ f 48.3333333333 79.0183991701 205.7460565259 -109.0793898593
BXD2/TyJ m 73.5 96.7773791292 266.2904254219 -119.2904254219
BXD31/TyJ f 10.5 96.7773791292 203.2904254219 -182.2904254219
BXD31/TyJ m 7.0 68.4319410477 143.3234171637 -129.3234171637
BXD38/TyJ f 11.3333333333 79.0183991701 168.7460565259 -146.0793898593
BXD38/TyJ m 8.6666666667 79.0183991701 166.0793898593 -148.7460565259
BXD65/RwwJ f 54.5 96.7773791292 247.2904254219 -138.2904254219
BXD65/RwwJ m 4.5 96.7773791292 197.2904254219 -188.2904254219
BXD77/RwwJ f 6.6666666667 79.0183991701 164.0793898593 -150.7460565259
BXD77/RwwJ m 9.3333333333 79.0183991701 166.7460565259 -148.0793898593
BXD84/RwwJ f 16.5 96.7773791292 209.2904254219 -176.2904254219
BXD84/RwwJ m 11.6666666667 79.0183991701 169.0793898593 -145.7460565259
BXD98/RwwJ f 1.5 96.7773791292 194.2904254219 -191.2904254219
BXD98/RwwJ m 3.0 96.7773791292 195.7904254219 -189.7904254219
C3HeB/FeJ f 6.0 79.0183991701 163.4127231926 -151.4127231926
C3HeB/FeJ m 3.5 96.7773791292 196.2904254219 -189.2904254219
C3H/HeJ f 3.5 96.7773791292 196.2904254219 -189.2904254219
C3H/HeJ m 5.0 96.7773791292 197.7904254219 -187.7904254219
C57BL/10J f 2.5 96.7773791292 195.2904254219 -190.2904254219
C57BL/10J m 3.5 96.7773791292 196.2904254219 -189.2904254219
C57BR/cdJ f 7.6666666667 79.0183991701 165.0793898593 -149.7460565259
C57BR/cdJ m 6.5 96.7773791292 199.2904254219 -186.2904254219
C58/J f 5.3333333333 79.0183991701 162.7460565259 -152.0793898593
C58/J m 4.0 79.0183991701 161.4127231926 -153.4127231926
CBA/J f 14.0 79.0183991701 171.4127231926 -143.4127231926
CBA/J m 3.0 96.7773791292 195.7904254219 -189.7904254219
KK/HlJ f 3.0 96.7773791292 195.7904254219 -189.7904254219
KK/HlJ m 18.0 79.0183991701 175.4127231926 -139.4127231926
MA/MyJ f 104.0 79.0183991701 261.4127231926 -53.4127231926
MA/MyJ m 1.0 96.7773791292 193.7904254219 -191.7904254219
NOD/ShiLtJ f 100.3333333333 79.0183991701 257.7460565259 -57.0793898593
NOD/ShiLtJ m 8.3333333333 79.0183991701 165.7460565259 -149.0793898593
NZO/HlLtJ f 3.0 96.7773791292 195.7904254219 -189.7904254219
NZO/HlLtJ m 321.6666666667 79.0183991701 479.0793898593 164.2539434741
PL/J f 8.0 96.7773791292 200.7904254219 -184.7904254219
PL/J m 354.0 79.0183991701 511.4127231926 196.5872768074
SM/J f 13.0 68.4319410477 149.3234171637 -123.3234171637
SM/J m 9.0 68.4319410477 145.3234171637 -127.3234171637


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 10.8333333333 62.4695296095 135.2790178279 -113.6123511612
BALB/cByJ both 9.5 62.4695296095 133.9456844946 -114.9456844946
BALB/cJ both 4.75 62.4695296095 129.1956844946 -119.6956844946
BPL/1J both 75.6666666667 62.4695296095 200.1123511612 -48.7790178279
BXD11/TyJ both 92.25 68.4319410477 228.5734171637 -44.0734171637
BXD2/TyJ both 60.9166666667 62.4695296095 185.3623511612 -63.5290178279
BXD31/TyJ both 8.75 59.2637993776 126.8095423944 -109.3095423944
BXD38/TyJ both 10.0 55.8744458917 121.3076040145 -101.3076040145
BXD65/RwwJ both 29.5 68.4319410477 165.8234171637 -106.8234171637
BXD77/RwwJ both 8.0 55.8744458917 119.3076040145 -103.3076040145
BXD84/RwwJ both 14.0833333333 62.4695296095 138.5290178279 -110.3623511612
BXD98/RwwJ both 2.25 68.4319410477 138.5734171637 -134.0734171637
C3HeB/FeJ both 4.75 62.4695296095 129.1956844946 -119.6956844946
C3H/HeJ both 4.25 68.4319410477 140.5734171637 -132.0734171637
C57BL/10J both 3.0 68.4319410477 139.3234171637 -133.3234171637
C57BR/cdJ both 7.0833333333 62.4695296095 131.5290178279 -117.3623511612
C58/J both 4.6666666667 55.8744458917 115.9742706812 -106.6409373479
CBA/J both 8.5 62.4695296095 132.9456844946 -115.9456844946
KK/HlJ both 10.5 62.4695296095 134.9456844946 -113.9456844946
MA/MyJ both 52.5 62.4695296095 176.9456844946 -71.9456844946
NOD/ShiLtJ both 54.3333333333 55.8744458917 165.6409373479 -56.9742706812
NZO/HlLtJ both 162.3333333333 62.4695296095 286.7790178279 37.8876488388
PL/J both 181.0 62.4695296095 305.4456844946 56.5543155054
SM/J both 11.0 48.3886895646 107.395212711 -85.395212711




  GWAS USING LINEAR MIXED MODELS