MPD: Project measure / variable: Project1032 active_pct_d7

Project measure / variable: Project1032 active_pct_d7_control

ID, description, units	MPD:111446 active_pct_d7_control percentage of lever presses that are active (intravenous self administration), saline [%] day 7
Data set, strains	Project1032 HMDP 64 strains sex: both age: 9-15wks
Procedure	operant conditioning chamber
Ontology mappings

STRAIN COMPARISON PLOT

Dimensions Width: px Height: px

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Visualization Options Least squares means Alphabetical order Strains on X-axis Individual points

Project1032 - percentage of lever presses that are active (intravenous self administration), saline day 7

MEASURE SUMMARY

Measure Summary	Female	Male
Number of strains tested	57 strains	63 strains
Mean of the strain means	60.81 %	61.85 %
Median of the strain means	59.55 %	62.8 %
SD of the strain means	± 20.094	± 17.083
Coefficient of variation (CV)	0.3304	0.2762
Min–max range of strain means	19.2 – 100.0 %	22.2 – 100.0 %
Mean sample size per strain	2.2 mice	2.1 mice

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p value (Pr>F)
sex	1	4.2258	4.2258	0.0066	0.9353
strain	35	25703.1552	734.3759	1.1509	0.2846
sex:strain	35	15286.1038	436.7458	0.6845	0.9013
Residuals	117	74657.0867	638.0948

Q-Q normality assessment based on residuals

STRAIN MEANS (UNADJUSTED)

Strain	Sex	Mean	SD	N mice	SEM	CV	Min, Max	Z score
129S1/SvImJ	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.69
A/J	f	55.65	36.275	2	25.65	0.6518	30.0, 81.3	-0.26
A/J	m	81.93	31.292	3	18.067	0.3819	45.8, 100.0	1.18
AKR/J	f	43.5	51.62	2	36.5	1.1866	7.0, 80.0	-0.86
AKR/J	m	25.0	0.0	1	0.0	0.0	25.0, 25.0	-2.16
BALB/cByJ	f	40.3	31.816	3	18.369	0.7895	12.5, 75.0	-1.02
BALB/cByJ	m	59.23	13.267	3	7.6595	0.224	48.6, 74.1	-0.15
BALB/cJ	f	64.83	39.637	3	22.885	0.6114	19.2, 90.7	0.2
BALB/cJ	m	63.35	30.254	4	15.127	0.4776	20.9, 86.7	0.09
BPL/1J	f	66.65	47.164	2	33.35	0.7076	33.3, 100.0	0.29
BPL/1J	m	55.75	48.013	2	33.95	0.8612	21.8, 89.7	-0.36
BTBR T⁺ Itpr3^tf/J	m	22.2	0.0	1	0.0	0.0	22.2, 22.2	-2.32
BXD100/RwwJ	f	37.8	0.0	1	0.0	0.0	37.8, 37.8	-1.15
BXD100/RwwJ	m	57.95	17.89	2	12.65	0.3087	45.3, 70.6	-0.23
BXD11/TyJ	f	66.65	47.164	2	33.35	0.7076	33.3, 100.0	0.29
BXD11/TyJ	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.69
BXD15/TyJ	f	19.2	0.0	1	0.0	0.0	19.2, 19.2	-2.07
BXD15/TyJ	m	63.07	11.402	3	6.5831	0.1808	50.0, 71.0	0.07
BXD1/TyJ	f	100.0	0.0	3	0.0	0.0	100.0, 100.0	1.95
BXD1/TyJ	m	68.75	44.194	2	31.25	0.6428	37.5, 100.0	0.4
BXD21/TyJ	m	33.3	0.0	1	0.0	0.0	33.3, 33.3	-1.67
BXD28/TyJ	m	78.4	30.547	2	21.6	0.3896	56.8, 100.0	0.97
BXD2/TyJ	f	60.9	55.3	2	39.1	0.908	21.8, 100.0	0.0
BXD2/TyJ	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.69
BXD31/TyJ	f	53.03	9.4236	3	5.4407	0.1777	45.5, 63.6	-0.39
BXD31/TyJ	m	61.1	34.708	3	20.039	0.568	33.3, 100.0	-0.04
BXD32/TyJ	f	44.3	22.203	2	15.7	0.5012	28.6, 60.0	-0.82
BXD32/TyJ	m	62.8	21.213	2	15.0	0.3378	47.8, 77.8	0.06
BXD34/TyJ	f	84.35	3.6062	2	2.55	0.0428	81.8, 86.9	1.17
BXD34/TyJ	m	67.75	25.102	2	17.75	0.3705	50.0, 85.5	0.35
BXD38/TyJ	f	74.4	8.4006	3	4.8501	0.1129	64.7, 79.3	0.68
BXD38/TyJ	m	44.567	20.134	3	11.624	0.4518	22.9, 62.7	-1.01
BXD39/TyJ	f	44.4	3.2527	2	2.3	0.0733	42.1, 46.7	-0.82
BXD40/TyJ	f	81.3	23.443	3	13.535	0.2884	55.0, 100.0	1.02
BXD40/TyJ	m	64.0	19.799	2	14.0	0.3094	50.0, 78.0	0.13
BXD42/TyJ	f	43.433	39.535	3	22.826	0.9103	13.7, 88.3	-0.87
BXD42/TyJ	m	42.433	8.718	3	5.0333	0.2055	32.9, 50.0	-1.14
BXD48a/RwwJ	f	38.867	25.278	3	14.594	0.6504	14.3, 64.8	-1.09
BXD48a/RwwJ	m	55.77	24.243	3	13.997	0.4347	28.6, 75.2	-0.36
BXD50/RwwJ	f	33.5	12.445	2	8.8	0.3715	24.7, 42.3	-1.36
BXD50/RwwJ	m	53.0	0.0	1	0.0	0.0	53.0, 53.0	-0.52
BXD55/RwwJ	f	77.9	0.0	1	0.0	0.0	77.9, 77.9	0.85
BXD55/RwwJ	m	39.75	25.385	2	17.95	0.6386	21.8, 57.7	-1.29
BXD56/RwwJ	m	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.23
BXD60/RwwJ	f	59.55	10.112	2	7.15	0.1698	52.4, 66.7	-0.06
BXD60/RwwJ	m	64.0	0.0	1	0.0	0.0	64.0, 64.0	0.13
BXD61/RwwJ	f	55.1	16.405	2	11.6	0.2977	43.5, 66.7	-0.28
BXD61/RwwJ	m	64.97	15.372	3	8.8751	0.2366	48.6, 79.1	0.18
BXD62/RwwJ	f	77.77	38.509	3	22.233	0.4952	33.3, 100.0	0.84
BXD62/RwwJ	m	43.2	14.729	3	8.5035	0.3409	26.3, 53.3	-1.09
BXD63/RwwJ	f	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.54
BXD63/RwwJ	m	76.25	16.758	2	11.85	0.2198	64.4, 88.1	0.84
BXD65/RwwJ	f	76.0	31.373	3	18.113	0.4128	40.5, 100.0	0.76
BXD65/RwwJ	m	80.0	0.0	1	0.0	0.0	80.0, 80.0	1.06
BXD68/RwwJ	f	73.7	6.9296	2	4.9	0.094	68.8, 78.6	0.64
BXD68/RwwJ	m	70.85	5.869	2	4.15	0.0828	66.7, 75.0	0.53
BXD69/RwwJ	f	92.7	0.0	1	0.0	0.0	92.7, 92.7	1.59
BXD69/RwwJ	m	78.6	0.0	1	0.0	0.0	78.6, 78.6	0.98
BXD70/RwwJ	f	20.6	0.0	1	0.0	0.0	20.6, 20.6	-2.0
BXD70/RwwJ	m	79.8	0.0	1	0.0	0.0	79.8, 79.8	1.05
BXD71/RwwJ	f	43.2	9.6167	2	6.8	0.2226	36.4, 50.0	-0.88
BXD71/RwwJ	m	52.5	0.0	1	0.0	0.0	52.5, 52.5	-0.55
BXD73a/RwwJ	f	66.7	0.0	1	0.0	0.0	66.7, 66.7	0.29
BXD73a/RwwJ	m	89.15	1.3435	2	0.95	0.0151	88.2, 90.1	1.6
BXD75/RwwJ	f	77.6	0.0	1	0.0	0.0	77.6, 77.6	0.84
BXD75/RwwJ	m	83.1	0.0	1	0.0	0.0	83.1, 83.1	1.24
BXD77/RwwJ	f	60.13	34.287	3	19.796	0.5702	29.2, 97.0	-0.03
BXD77/RwwJ	m	52.83	37.855	3	21.856	0.7165	10.0, 81.8	-0.53
BXD84/RwwJ	f	84.3	22.203	2	15.7	0.2634	68.6, 100.0	1.17
BXD84/RwwJ	m	63.67	11.856	3	6.8453	0.1862	50.0, 71.2	0.11
BXD90/RwwJ	m	81.8	0.0	1	0.0	0.0	81.8, 81.8	1.17
BXD98/RwwJ	f	73.93	16.302	3	9.4118	0.2205	62.5, 92.6	0.65
BXD98/RwwJ	m	65.33	26.608	3	15.362	0.4073	34.9, 84.2	0.2
BXD99/RwwJ	m	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.23
C3HeB/FeJ	f	61.4	36.052	3	20.814	0.5872	28.6, 100.0	0.03
C3HeB/FeJ	m	54.05	45.75	2	32.35	0.8464	21.7, 86.4	-0.46
C3H/HeJ	f	26.8	2.5456	2	1.8	0.095	25.0, 28.6	-1.69
C3H/HeJ	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.69
C57BL/10J	f	53.27	32.062	3	18.511	0.6019	16.3, 73.5	-0.38
C57BL/10J	m	66.0	21.612	3	12.478	0.3275	42.2, 84.4	0.24
C57BL/6J	f	73.2	2.5456	2	1.8	0.0348	71.4, 75.0	0.62
C57BL/6J	m	40.1	17.519	3	10.115	0.4369	27.0, 60.0	-1.27
C57BLKS/J	f	46.45	5.0205	2	3.55	0.1081	42.9, 50.0	-0.71
C57BLKS/J	m	41.65	11.809	2	8.35	0.2835	33.3, 50.0	-1.18
C57BR/cdJ	f	49.6	32.935	3	19.015	0.664	13.9, 78.8	-0.56
C57BR/cdJ	m	71.33	34.925	3	20.164	0.4896	31.5, 96.7	0.56
C57L/J	f	58.8	4.8083	2	3.4	0.0818	55.4, 62.2	-0.1
C57L/J	m	77.27	22.935	3	13.241	0.2968	50.8, 91.3	0.9
C58/J	f	56.27	8.7272	3	5.0386	0.1551	46.2, 61.7	-0.23
C58/J	m	41.167	16.579	3	9.5719	0.4027	22.2, 52.9	-1.21
CBA/J	f	77.77	25.455	3	14.697	0.3273	50.0, 100.0	0.84
CBA/J	m	59.57	10.415	3	6.0129	0.1748	48.0, 68.2	-0.13
DBA/1J	f	74.0	10.324	2	7.3	0.1395	66.7, 81.3	0.66
DBA/1J	m	100.0	0.0	2	0.0	0.0	100.0, 100.0	2.23
DBA/2J	f	100.0	0.0	2	0.0	0.0	100.0, 100.0	1.95
DBA/2J	m	60.0	0.0	1	0.0	0.0	60.0, 60.0	-0.11
FVB/NJ	f	49.067	11.429	3	6.5983	0.2329	37.2, 60.0	-0.58
FVB/NJ	m	41.333	36.451	3	21.045	0.8819	7.6, 80.0	-1.2
I/LnJ	f	70.15	3.6062	2	2.55	0.0514	67.6, 72.7	0.46
I/LnJ	m	71.25	32.456	2	22.95	0.4555	48.3, 94.2	0.55
KK/HlJ	f	45.567	5.0954	3	2.9418	0.1118	40.0, 50.0	-0.76
KK/HlJ	m	67.87	29.967	3	17.301	0.4416	38.5, 98.4	0.35
LP/J	f	100.0	0.0	1	0.0	0.0	100.0, 100.0	1.95
LP/J	m	52.4	6.6468	2	4.7	0.1268	47.7, 57.1	-0.55
MA/MyJ	f	55.05	7.1418	2	5.05	0.1297	50.0, 60.1	-0.29
MA/MyJ	m	41.6	0.0	1	0.0	0.0	41.6, 41.6	-1.19
MRL/MpJ	f	75.0	35.355	2	25.0	0.4714	50.0, 100.0	0.71
MRL/MpJ	m	75.57	21.423	3	12.369	0.2835	60.0, 100.0	0.8
NOD/ShiLtJ	f	28.6	24.125	3	13.929	0.8435	7.7, 55.0	-1.6
NOD/ShiLtJ	m	51.7	27.86	2	19.7	0.5389	32.0, 71.4	-0.59
NZB/BlNJ	f	54.8	16.829	2	11.9	0.3071	42.9, 66.7	-0.3
NZB/BlNJ	m	76.95	2.7577	2	1.95	0.0358	75.0, 78.9	0.88
NZO/HlLtJ	f	59.45	29.062	2	20.55	0.4888	38.9, 80.0	-0.07
NZO/HlLtJ	m	63.13	32.729	3	18.896	0.5184	37.5, 100.0	0.08
NZW/LacJ	f	100.0	0.0	2	0.0	0.0	100.0, 100.0	1.95
NZW/LacJ	m	85.7	0.0	1	0.0	0.0	85.7, 85.7	1.4
PL/J	f	32.8	24.91	3	14.382	0.7594	11.1, 60.0	-1.39
PL/J	m	52.8	15.698	2	11.1	0.2973	41.7, 63.9	-0.53
SM/J	f	76.13	20.45	3	11.807	0.2686	61.5, 99.5	0.76
SM/J	m	58.73	7.3908	3	4.2671	0.1258	52.1, 66.7	-0.18

LEAST SQUARES MEANS (MODEL-ADJUSTED)

Strain	Sex	Mean	SEM	UpperCL	LowerCL
A/J	f	55.65	17.8618974053	91.0245518243	20.2754481757
A/J	m	81.9333333333	14.5841781603	110.8165339497	53.050132717
BALB/cByJ	f	40.3	14.5841781603	69.1832006164	11.4167993836
BALB/cByJ	m	59.2333333333	14.5841781603	88.1165339497	30.350132717
BALB/cJ	f	64.8333333333	14.5841781603	93.7165339497	35.950132717
BALB/cJ	m	63.35	12.6302687801	88.3635854764	38.3364145236
BPL/1J	f	66.65	17.8618974053	102.0245518243	31.2754481757
BPL/1J	m	55.75	17.8618974053	91.1245518243	20.3754481757
BXD1/TyJ	f	100.0	14.5841781603	128.8832006164	71.1167993836
BXD1/TyJ	m	68.75	17.8618974053	104.1245518243	33.3754481757
BXD31/TyJ	f	53.0333333333	14.5841781603	81.9165339497	24.150132717
BXD31/TyJ	m	61.1	14.5841781603	89.9832006164	32.2167993836
BXD32/TyJ	f	44.3	17.8618974053	79.6745518243	8.9254481757
BXD32/TyJ	m	62.8	17.8618974053	98.1745518243	27.4254481757
BXD34/TyJ	f	84.35	17.8618974053	119.7245518243	48.9754481757
BXD34/TyJ	m	67.75	17.8618974053	103.1245518243	32.3754481757
BXD38/TyJ	f	74.4	14.5841781603	103.2832006164	45.5167993836
BXD38/TyJ	m	44.5666666667	14.5841781603	73.449867283	15.6834660503
BXD40/TyJ	f	81.3	14.5841781603	110.1832006164	52.4167993836
BXD40/TyJ	m	64.0	17.8618974053	99.3745518243	28.6254481757
BXD42/TyJ	f	43.4333333333	14.5841781603	72.3165339497	14.550132717
BXD42/TyJ	m	42.4333333333	14.5841781603	71.3165339497	13.550132717
BXD48a/RwwJ	f	38.8666666667	14.5841781603	67.749867283	9.9834660503
BXD48a/RwwJ	m	55.7666666667	14.5841781603	84.649867283	26.8834660503
BXD61/RwwJ	f	55.1	17.8618974053	90.4745518243	19.7254481757
BXD61/RwwJ	m	64.9666666667	14.5841781603	93.849867283	36.0834660503
BXD62/RwwJ	f	77.7666666667	14.5841781603	106.649867283	48.8834660503
BXD62/RwwJ	m	43.2	14.5841781603	72.0832006164	14.3167993836
BXD68/RwwJ	f	73.7	17.8618974053	109.0745518243	38.3254481757
BXD68/RwwJ	m	70.85	17.8618974053	106.2245518243	35.4754481757
BXD77/RwwJ	f	60.1333333333	14.5841781603	89.0165339497	31.250132717
BXD77/RwwJ	m	52.8333333333	14.5841781603	81.7165339497	23.950132717
BXD84/RwwJ	f	84.3	17.8618974053	119.6745518243	48.9254481757
BXD84/RwwJ	m	63.6666666667	14.5841781603	92.549867283	34.7834660503
BXD98/RwwJ	f	73.9333333333	14.5841781603	102.8165339497	45.050132717
BXD98/RwwJ	m	65.3333333333	14.5841781603	94.2165339497	36.450132717
C3HeB/FeJ	f	61.4	14.5841781603	90.2832006164	32.5167993836
C3HeB/FeJ	m	54.05	17.8618974053	89.4245518243	18.6754481757
C57BL/10J	f	53.2666666667	14.5841781603	82.149867283	24.3834660503
C57BL/10J	m	66.0	14.5841781603	94.8832006164	37.1167993836
C57BL/6J	f	73.2	17.8618974053	108.5745518243	37.8254481757
C57BL/6J	m	40.1	14.5841781603	68.9832006164	11.2167993836
C57BLKS/J	f	46.45	17.8618974053	81.8245518243	11.0754481757
C57BLKS/J	m	41.65	17.8618974053	77.0245518243	6.2754481757
C57BR/cdJ	f	49.6	14.5841781603	78.4832006164	20.7167993836
C57BR/cdJ	m	71.3333333333	14.5841781603	100.2165339497	42.450132717
C57L/J	f	58.8	17.8618974053	94.1745518243	23.4254481757
C57L/J	m	77.2666666667	14.5841781603	106.149867283	48.3834660503
C58/J	f	56.2666666667	14.5841781603	85.149867283	27.3834660503
C58/J	m	41.1666666667	14.5841781603	70.049867283	12.2834660503
CBA/J	f	77.7666666667	14.5841781603	106.649867283	48.8834660503
CBA/J	m	59.5666666667	14.5841781603	88.449867283	30.6834660503
DBA/1J	f	74.0	17.8618974053	109.3745518243	38.6254481757
DBA/1J	m	100.0	17.8618974053	135.3745518243	64.6254481757
FVB/NJ	f	49.0666666667	14.5841781603	77.949867283	20.1834660503
FVB/NJ	m	41.3333333333	14.5841781603	70.2165339497	12.450132717
I/LnJ	f	70.15	17.8618974053	105.5245518243	34.7754481757
I/LnJ	m	71.25	17.8618974053	106.6245518243	35.8754481757
KK/HlJ	f	45.5666666667	14.5841781603	74.449867283	16.6834660503
KK/HlJ	m	67.8666666667	14.5841781603	96.749867283	38.9834660503
MRL/MpJ	f	75.0	17.8618974053	110.3745518243	39.6254481757
MRL/MpJ	m	75.5666666667	14.5841781603	104.449867283	46.6834660503
NOD/ShiLtJ	f	28.6	14.5841781603	57.4832006164	-0.2832006164
NOD/ShiLtJ	m	51.7	17.8618974053	87.0745518243	16.3254481757
NZB/BlNJ	f	54.8	17.8618974053	90.1745518243	19.4254481757
NZB/BlNJ	m	76.95	17.8618974053	112.3245518243	41.5754481757
NZO/HlLtJ	f	59.45	17.8618974053	94.8245518243	24.0754481757
NZO/HlLtJ	m	63.1333333333	14.5841781603	92.0165339497	34.250132717
PL/J	f	32.8	14.5841781603	61.6832006164	3.9167993836
PL/J	m	52.8	17.8618974053	88.1745518243	17.4254481757
SM/J	f	76.1333333333	14.5841781603	105.0165339497	47.250132717
SM/J	m	58.7333333333	14.5841781603	87.6165339497	29.850132717

LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED

Strain	Sex	Mean	SEM	UpperCL	LowerCL
A/J	both	68.7916666667	11.5298051971	91.6258416825	45.9574916509
BALB/cByJ	both	49.7666666667	10.3125712752	70.1901736849	29.3431596485
BALB/cJ	both	64.0916666667	9.6465271221	83.1961081413	44.9872251921
BPL/1J	both	61.2	12.6302687801	86.2135854764	36.1864145236
BXD1/TyJ	both	84.375	11.5298051971	107.2091750158	61.5408249842
BXD31/TyJ	both	57.0666666667	10.3125712752	77.4901736849	36.6431596485
BXD32/TyJ	both	53.55	12.6302687801	78.5635854764	28.5364145236
BXD34/TyJ	both	76.05	12.6302687801	101.0635854764	51.0364145236
BXD38/TyJ	both	59.4833333333	10.3125712752	79.9068403515	39.0598263151
BXD40/TyJ	both	72.65	11.5298051971	95.4841750158	49.8158249842
BXD42/TyJ	both	42.9333333333	10.3125712752	63.3568403515	22.5098263151
BXD48a/RwwJ	both	47.3166666667	10.3125712752	67.7401736849	26.8931596485
BXD61/RwwJ	both	60.0333333333	11.5298051971	82.8675083491	37.1991583175
BXD62/RwwJ	both	60.4833333333	10.3125712752	80.9068403515	40.0598263151
BXD68/RwwJ	both	72.275	12.6302687801	97.2885854764	47.2614145236
BXD77/RwwJ	both	56.4833333333	10.3125712752	76.9068403515	36.0598263151
BXD84/RwwJ	both	73.9833333333	11.5298051971	96.8175083491	51.1491583175
BXD98/RwwJ	both	69.6333333333	10.3125712752	90.0568403515	49.2098263151
C3HeB/FeJ	both	57.725	11.5298051971	80.5591750158	34.8908249842
C57BL/10J	both	59.6333333333	10.3125712752	80.0568403515	39.2098263151
C57BL/6J	both	56.65	11.5298051971	79.4841750158	33.8158249842
C57BLKS/J	both	44.05	12.6302687801	69.0635854764	19.0364145236
C57BR/cdJ	both	60.4666666667	10.3125712752	80.8901736849	40.0431596485
C57L/J	both	68.0333333333	11.5298051971	90.8675083491	45.1991583175
C58/J	both	48.7166666667	10.3125712752	69.1401736849	28.2931596485
CBA/J	both	68.6666666667	10.3125712752	89.0901736849	48.2431596485
DBA/1J	both	87.0	12.6302687801	112.0135854764	61.9864145236
FVB/NJ	both	45.2	10.3125712752	65.6235070182	24.7764929818
I/LnJ	both	70.7	12.6302687801	95.7135854764	45.6864145236
KK/HlJ	both	56.7166666667	10.3125712752	77.1401736849	36.2931596485
MRL/MpJ	both	75.2833333333	11.5298051971	98.1175083491	52.4491583175
NOD/ShiLtJ	both	40.15	11.5298051971	62.9841750158	17.3158249842
NZB/BlNJ	both	65.875	12.6302687801	90.8885854764	40.8614145236
NZO/HlLtJ	both	61.2916666667	11.5298051971	84.1258416825	38.4574916509
PL/J	both	42.8	11.5298051971	65.6341750158	19.9658249842
SM/J	both	67.4333333333	10.3125712752	87.8568403515	47.0098263151

INDIVIDUAL ANIMAL VALUES

Click here to view individual animal values

GWAS USING LINEAR MIXED MODELS