Project measure / variable:   Project1032   infusions_d8_cocaine

ID, description, units MPD:111431   infusions_d8_cocaine   number of infusions earned (intravenous self administration), cocaine   [n]  day 8  
cocaine study
Data set, strains Project1032   HMDP   66 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of infusions earned (intravenous self administration), cocaine day 8



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested61 strains62 strains
Mean of the strain means28.402   n 27.609   n
Median of the strain means29.0   n 28.5   n
SD of the strain means± 17.178 ± 12.876
Coefficient of variation (CV)0.6048 0.4664
Min–max range of strain means1.0   –   65.0   n 1.0   –   56.5   n
Mean sample size per strain2.1   mice 2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 369.1085 369.1085 1.5188 0.2204
strain 31 14055.06 453.389 1.8656 0.0098
sex:strain 31 13028.0587 420.26 1.7293 0.0204
Residuals 111 26975.75 243.0248


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 56.5 0.70711   2   0.5 0.0125 56.0, 57.0 2.24
129X1/SvJ f 48.0 0.0   1   0.0 0.0 48.0, 48.0 1.14
A/J f 21.333 14.572   3 8.413 0.683 5.0, 33.0 -0.41
A/J m 2.0 1.7321   3 1.0 0.866 1.0, 4.0 -1.99
AKR/J f 10.0 11.314   2   8.0 1.1314 2.0, 18.0 -1.07
AKR/J m 23.0 4.2426   2   3.0 0.1845 20.0, 26.0 -0.36
BALB/cByJ f 45.667 17.474   3 10.088 0.3826 31.0, 65.0 1.01
BALB/cByJ m 11.667 11.547   3 6.6667 0.9897 5.0, 25.0 -1.24
BALB/cJ f 20.5 20.506   2   14.5 1.0003 6.0, 35.0 -0.46
BALB/cJ m 16.333 12.097   3 6.9841 0.7406 7.0, 30.0 -0.88
BPL/1J f 54.67 17.898   3 10.333 0.3274 34.0, 65.0 1.53
BPL/1J m 26.0 8.8882   3 5.1316 0.3419 16.0, 33.0 -0.12
BTBR T+ Itpr3tf/J f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -1.25
BTBR T+ Itpr3tf/J m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -1.99
BXD100/RwwJ f 28.5 12.021   2   8.5 0.4218 20.0, 37.0 0.01
BXD100/RwwJ m 30.0 0.0   1   0.0 0.0 30.0, 30.0 0.19
BXD11/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.6
BXD11/TyJ m 36.0 0.0   1   0.0 0.0 36.0, 36.0 0.65
BXD15/TyJ f 54.0 14.422   3 8.3267 0.2671 38.0, 66.0 1.49
BXD15/TyJ m 46.0 0.0   1   0.0 0.0 46.0, 46.0 1.43
BXD1/TyJ f 29.5 38.891   2   27.5 1.3183 2.0, 57.0 0.06
BXD1/TyJ m 30.333 4.5092   3 2.6034 0.1487 26.0, 35.0 0.21
BXD21/TyJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 0.85
BXD21/TyJ m 51.5 19.092   2   13.5 0.3707 38.0, 65.0 1.86
BXD28/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.6
BXD2/TyJ f 25.0 7.9373   3 4.5826 0.3175 19.0, 34.0 -0.2
BXD2/TyJ m 55.67 8.6217   3 4.9777 0.1549 48.0, 65.0 2.18
BXD31/TyJ f 49.667 20.793   3 12.005 0.4186 26.0, 65.0 1.24
BXD31/TyJ m 34.75 24.157   4 12.079 0.6952 6.0, 65.0 0.55
BXD32/TyJ f 10.5 10.607   2   7.5 1.0102 3.0, 18.0 -1.04
BXD32/TyJ m 27.0 22.627   2   16.0 0.8381 11.0, 43.0 -0.05
BXD34/TyJ f 18.0 0.0   2   0.0 0.0 18.0, 18.0 -0.61
BXD34/TyJ m 32.0 0.0   1   0.0 0.0 32.0, 32.0 0.34
BXD38/TyJ f 41.0 6.5574   3 3.7859 0.1599 35.0, 48.0 0.73
BXD38/TyJ m 31.667 4.9329   3 2.848 0.1558 26.0, 35.0 0.32
BXD39/TyJ f 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.84
BXD39/TyJ m 21.333 12.097   3 6.9841 0.567 12.0, 35.0 -0.49
BXD40/TyJ m 24.667 24.542   3 14.17 0.995 1.0, 50.0 -0.23
BXD42/TyJ f 39.5 0.70711   2   0.5 0.0179 39.0, 40.0 0.65
BXD42/TyJ m 49.333 11.504   3 6.6416 0.2332 38.0, 61.0 1.69
BXD48a/RwwJ f 36.5 6.364   2   4.5 0.1744 32.0, 41.0 0.47
BXD48a/RwwJ m 26.0 17.059   3 9.8489 0.6561 7.0, 40.0 -0.12
BXD50/RwwJ f 29.0 0.0   1   0.0 0.0 29.0, 29.0 0.03
BXD50/RwwJ m 24.5 20.506   2   14.5 0.837 10.0, 39.0 -0.24
BXD55/RwwJ f 49.5 16.263   2   11.5 0.3286 38.0, 61.0 1.23
BXD55/RwwJ m 25.0 0.0   1   0.0 0.0 25.0, 25.0 -0.2
BXD56/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -2.07
BXD60/RwwJ f 47.0 0.0   1   0.0 0.0 47.0, 47.0 1.08
BXD60/RwwJ m 41.5 13.435   2   9.5 0.3237 32.0, 51.0 1.08
BXD61/RwwJ f 13.667 19.399   3 11.2 1.4195 1.0, 36.0 -0.86
BXD61/RwwJ m 37.0 0.0   1   0.0 0.0 37.0, 37.0 0.73
BXD62/RwwJ f 39.0 28.284   2   20.0 0.7252 19.0, 59.0 0.62
BXD62/RwwJ m 34.0 19.799   2   14.0 0.5823 20.0, 48.0 0.5
BXD63/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.6
BXD63/RwwJ m 21.0 0.0   1   0.0 0.0 21.0, 21.0 -0.51
BXD65/RwwJ f 51.0 20.881   3 12.055 0.4094 27.0, 65.0 1.32
BXD65/RwwJ m 29.0 29.614   3 17.098 1.0212 1.0, 60.0 0.11
BXD68/RwwJ f 65.0 0.0   1   0.0 0.0 65.0, 65.0 2.13
BXD68/RwwJ m 24.667 20.648   3 11.921 0.8371 1.0, 39.0 -0.23
BXD69/RwwJ f 35.5 2.1213   2   1.5 0.0598 34.0, 37.0 0.41
BXD70/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -1.54
BXD70/RwwJ m 50.0 0.0   1   0.0 0.0 50.0, 50.0 1.74
BXD71/RwwJ f 31.0 0.0   1   0.0 0.0 31.0, 31.0 0.15
BXD71/RwwJ m 20.0 14.142   2   10.0 0.7071 10.0, 30.0 -0.59
BXD73a/RwwJ f 26.5 12.021   2   8.5 0.4536 18.0, 35.0 -0.11
BXD73a/RwwJ m 34.0 0.0   1   0.0 0.0 34.0, 34.0 0.5
BXD75/RwwJ f 48.0 0.0   1   0.0 0.0 48.0, 48.0 1.14
BXD75/RwwJ m 30.5 17.678   2   12.5 0.5796 18.0, 43.0 0.22
BXD77/RwwJ f 18.0 16.971   2   12.0 0.9428 6.0, 30.0 -0.61
BXD77/RwwJ m 24.667 29.939   3 17.285 1.2137 4.0, 59.0 -0.23
BXD84/RwwJ f 8.0 9.5394   3 5.5076 1.1924 2.0, 19.0 -1.19
BXD84/RwwJ m 20.667 15.044   3 8.6859 0.728 5.0, 35.0 -0.54
BXD90/RwwJ m 25.5 14.849   2   10.5 0.5823 15.0, 36.0 -0.16
BXD98/RwwJ f 34.5 4.9497   2   3.5 0.1435 31.0, 38.0 0.36
BXD98/RwwJ m 28.667 2.0817   3 1.2019 0.0726 27.0, 31.0 0.08
BXD99/RwwJ f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.78
BXD99/RwwJ m 34.0 0.0   1   0.0 0.0 34.0, 34.0 0.5
C3HeB/FeJ f 6.6667 6.4291   3 3.7118 0.9644 2.0, 14.0 -1.27
C3HeB/FeJ m 34.0 15.556   2   11.0 0.4575 23.0, 45.0 0.5
C3H/HeJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -1.48
C3H/HeJ m 21.0 0.0   1   0.0 0.0 21.0, 21.0 -0.51
C57BL/10J f 28.333 24.42   3 14.099 0.8619 1.0, 48.0 0.0
C57BL/10J m 25.0 5.0   3 2.8868 0.2 20.0, 30.0 -0.2
C57BL/6J f 18.5 24.749   2   17.5 1.3378 1.0, 36.0 -0.58
C57BL/6J m 28.333 14.012   3 8.0898 0.4945 17.0, 44.0 0.06
C57BLKS/J f 39.5 10.607   2   7.5 0.2685 32.0, 47.0 0.65
C57BLKS/J m 16.5 21.92   2   15.5 1.3285 1.0, 32.0 -0.86
C57BR/cdJ f 46.667 5.6862   3 3.283 0.1218 42.0, 53.0 1.06
C57BR/cdJ m 31.0 5.0   3 2.8868 0.1613 26.0, 36.0 0.26
C57L/J f 55.0 0.0   1   0.0 0.0 55.0, 55.0 1.55
C57L/J m 35.333 3.5119   3 2.0276 0.0994 32.0, 39.0 0.6
C58/J f 43.333 11.504   3 6.6416 0.2655 32.0, 55.0 0.87
C58/J m 32.667 12.503   3 7.2188 0.3828 20.0, 45.0 0.39
CBA/J f 17.667 15.275   3 8.8192 0.8646 1.0, 31.0 -0.62
CBA/J m 27.0 3.6056   3 2.0817 0.1335 24.0, 31.0 -0.05
DBA/1J f 13.667 9.2916   3 5.3645 0.6799 3.0, 20.0 -0.86
DBA/1J m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -1.76
DBA/2J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -2.07
FVB/NJ f 42.0 0.0   1   0.0 0.0 42.0, 42.0 0.79
FVB/NJ m 3.0 1.4142   2   1.0 0.4714 2.0, 4.0 -1.91
I/LnJ f 38.0 8.4853   2   6.0 0.2233 32.0, 44.0 0.56
I/LnJ m 33.0 0.0   1   0.0 0.0 33.0, 33.0 0.42
KK/HlJ f 17.0 14.422   3 8.3267 0.8484 1.0, 29.0 -0.66
KK/HlJ m 45.667 14.468   3 8.3533 0.3168 29.0, 55.0 1.4
LP/J f 5.0 1.4142   2   1.0 0.2828 4.0, 6.0 -1.36
LP/J m 31.0 8.4853   2   6.0 0.2737 25.0, 37.0 0.26
MA/MyJ f 49.667 9.0738   3 5.2387 0.1827 43.0, 60.0 1.24
MA/MyJ m 32.0 10.536   3 6.0828 0.3292 22.0, 43.0 0.34
MRL/MpJ f 41.0 32.527   2   23.0 0.7933 18.0, 64.0 0.73
MRL/MpJ m 13.333 20.502   3 11.837 1.5377 1.0, 37.0 -1.11
NOD/ShiLtJ f 32.333 18.583   3 10.729 0.5747 11.0, 45.0 0.23
NOD/ShiLtJ m 30.0 4.0   3 2.3094 0.1333 26.0, 34.0 0.19
NZB/BlNJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.6
NZB/BlNJ m 27.5 23.335   2   16.5 0.8485 11.0, 44.0 -0.01
NZO/HlLtJ f 33.0 6.245   3 3.6056 0.1892 28.0, 40.0 0.27
NZO/HlLtJ m 39.0 8.7178   3 5.0332 0.2235 33.0, 49.0 0.88
NZW/LacJ f 15.667 22.03   3 12.719 1.4062 1.0, 41.0 -0.74
NZW/LacJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -1.6
PL/J f 28.5 7.7782   2   5.5 0.2729 23.0, 34.0 0.01
PL/J m 33.0 31.048   3 17.926 0.9409 3.0, 65.0 0.42
SJL/J f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -1.25
SM/J f 38.0 16.753   4 8.3766 0.4409 24.0, 59.0 0.56
SM/J m 21.0 2.9439   4 1.472 0.1402 18.0, 24.0 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 21.3333333333 9.0004587804 39.1683432511 3.4983234156
A/J m 2.0 9.0004587804 19.8350099177 -15.8350099177
AKR/J f 10.0 11.0232657315 31.843336928 -11.843336928
AKR/J m 23.0 11.0232657315 44.843336928 1.156663072
BALB/cByJ f 45.6666666667 9.0004587804 63.5016765844 27.8316567489
BALB/cByJ m 11.6666666667 9.0004587804 29.5016765844 -6.1683432511
BALB/cJ f 20.5 11.0232657315 42.343336928 -1.343336928
BALB/cJ m 16.3333333333 9.0004587804 34.1683432511 -1.5016765844
BPL/1J f 54.6666666667 9.0004587804 72.5016765844 36.8316567489
BPL/1J m 26.0 9.0004587804 43.8350099177 8.1649900823
BXD1/TyJ f 29.5 11.0232657315 51.343336928 7.656663072
BXD1/TyJ m 30.3333333333 9.0004587804 48.1683432511 12.4983234156
BXD2/TyJ f 25.0 9.0004587804 42.8350099177 7.1649900823
BXD2/TyJ m 55.6666666667 9.0004587804 73.5016765844 37.8316567489
BXD31/TyJ f 49.6666666667 9.0004587804 67.5016765844 31.8316567489
BXD31/TyJ m 34.75 7.7946259496 50.1955716655 19.3044283345
BXD32/TyJ f 10.5 11.0232657315 32.343336928 -11.343336928
BXD32/TyJ m 27.0 11.0232657315 48.843336928 5.156663072
BXD38/TyJ f 41.0 9.0004587804 58.8350099177 23.1649900823
BXD38/TyJ m 31.6666666667 9.0004587804 49.5016765844 13.8316567489
BXD42/TyJ f 39.5 11.0232657315 61.343336928 17.656663072
BXD42/TyJ m 49.3333333333 9.0004587804 67.1683432511 31.4983234156
BXD48a/RwwJ f 36.5 11.0232657315 58.343336928 14.656663072
BXD48a/RwwJ m 26.0 9.0004587804 43.8350099177 8.1649900823
BXD62/RwwJ f 39.0 11.0232657315 60.843336928 17.156663072
BXD62/RwwJ m 34.0 11.0232657315 55.843336928 12.156663072
BXD65/RwwJ f 51.0 9.0004587804 68.8350099177 33.1649900823
BXD65/RwwJ m 29.0 9.0004587804 46.8350099177 11.1649900823
BXD77/RwwJ f 18.0 11.0232657315 39.843336928 -3.843336928
BXD77/RwwJ m 24.6666666667 9.0004587804 42.5016765844 6.8316567489
BXD84/RwwJ f 8.0 9.0004587804 25.8350099177 -9.8350099177
BXD84/RwwJ m 20.6666666667 9.0004587804 38.5016765844 2.8316567489
BXD98/RwwJ f 34.5 11.0232657315 56.343336928 12.656663072
BXD98/RwwJ m 28.6666666667 9.0004587804 46.5016765844 10.8316567489
C3HeB/FeJ f 6.6666666667 9.0004587804 24.5016765844 -11.1683432511
C3HeB/FeJ m 34.0 11.0232657315 55.843336928 12.156663072
C57BL/10J f 28.3333333333 9.0004587804 46.1683432511 10.4983234156
C57BL/10J m 25.0 9.0004587804 42.8350099177 7.1649900823
C57BL/6J f 18.5 11.0232657315 40.343336928 -3.343336928
C57BL/6J m 28.3333333333 9.0004587804 46.1683432511 10.4983234156
C57BLKS/J f 39.5 11.0232657315 61.343336928 17.656663072
C57BLKS/J m 16.5 11.0232657315 38.343336928 -5.343336928
C57BR/cdJ f 46.6666666667 9.0004587804 64.5016765844 28.8316567489
C57BR/cdJ m 31.0 9.0004587804 48.8350099177 13.1649900823
C58/J f 43.3333333333 9.0004587804 61.1683432511 25.4983234156
C58/J m 32.6666666667 9.0004587804 50.5016765844 14.8316567489
CBA/J f 17.6666666667 9.0004587804 35.5016765844 -0.1683432511
CBA/J m 27.0 9.0004587804 44.8350099177 9.1649900823
KK/HlJ f 17.0 9.0004587804 34.8350099177 -0.8350099177
KK/HlJ m 45.6666666667 9.0004587804 63.5016765844 27.8316567489
LP/J f 5.0 11.0232657315 26.843336928 -16.843336928
LP/J m 31.0 11.0232657315 52.843336928 9.156663072
MA/MyJ f 49.6666666667 9.0004587804 67.5016765844 31.8316567489
MA/MyJ m 32.0 9.0004587804 49.8350099177 14.1649900823
MRL/MpJ f 41.0 11.0232657315 62.843336928 19.156663072
MRL/MpJ m 13.3333333333 9.0004587804 31.1683432511 -4.5016765844
NOD/ShiLtJ f 32.3333333333 9.0004587804 50.1683432511 14.4983234156
NOD/ShiLtJ m 30.0 9.0004587804 47.8350099177 12.1649900823
NZO/HlLtJ f 33.0 9.0004587804 50.8350099177 15.1649900823
NZO/HlLtJ m 39.0 9.0004587804 56.8350099177 21.1649900823
PL/J f 28.5 11.0232657315 50.343336928 6.656663072
PL/J m 33.0 9.0004587804 50.8350099177 15.1649900823
SM/J f 38.0 7.7946259496 53.4455716655 22.5544283345
SM/J m 21.0 7.7946259496 36.4455716655 5.5544283345


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 11.6666666667 6.3642854374 24.277923122 -0.9445897887
AKR/J both 16.5 7.7946259496 31.9455716655 1.0544283345
BALB/cByJ both 28.6666666667 6.3642854374 41.277923122 16.0554102113
BALB/cJ both 18.4166666667 7.1154874332 32.5164800246 4.3168533087
BPL/1J both 40.3333333333 6.3642854374 52.9445897887 27.722076878
BXD1/TyJ both 29.9166666667 7.1154874332 44.0164800246 15.8168533087
BXD2/TyJ both 40.3333333333 6.3642854374 52.9445897887 27.722076878
BXD31/TyJ both 42.2083333333 5.9532439046 54.0050835515 30.4115831152
BXD32/TyJ both 18.75 7.7946259496 34.1955716655 3.3044283345
BXD38/TyJ both 36.3333333333 6.3642854374 48.9445897887 23.722076878
BXD42/TyJ both 44.4166666667 7.1154874332 58.5164800246 30.3168533087
BXD48a/RwwJ both 31.25 7.1154874332 45.3498133579 17.1501866421
BXD62/RwwJ both 36.5 7.7946259496 51.9455716655 21.0544283345
BXD65/RwwJ both 40.0 6.3642854374 52.6112564554 27.3887435446
BXD77/RwwJ both 21.3333333333 7.1154874332 35.4331466913 7.2335199754
BXD84/RwwJ both 14.3333333333 6.3642854374 26.9445897887 1.722076878
BXD98/RwwJ both 31.5833333333 7.1154874332 45.6831466913 17.4835199754
C3HeB/FeJ both 20.3333333333 7.1154874332 34.4331466913 6.2335199754
C57BL/10J both 26.6666666667 6.3642854374 39.277923122 14.0554102113
C57BL/6J both 23.4166666667 7.1154874332 37.5164800246 9.3168533087
C57BLKS/J both 28.0 7.7946259496 43.4455716655 12.5544283345
C57BR/cdJ both 38.8333333333 6.3642854374 51.4445897887 26.222076878
C58/J both 38.0 6.3642854374 50.6112564554 25.3887435446
CBA/J both 22.3333333333 6.3642854374 34.9445897887 9.722076878
KK/HlJ both 31.3333333333 6.3642854374 43.9445897887 18.722076878
LP/J both 18.0 7.7946259496 33.4455716655 2.5544283345
MA/MyJ both 40.8333333333 6.3642854374 53.4445897887 28.222076878
MRL/MpJ both 27.1666666667 7.1154874332 41.2664800246 13.0668533087
NOD/ShiLtJ both 31.1666666667 6.3642854374 43.777923122 18.5554102113
NZO/HlLtJ both 36.0 6.3642854374 48.6112564554 23.3887435446
PL/J both 30.75 7.1154874332 44.8498133579 16.6501866421
SM/J both 29.5 5.5116328658 40.421668464 18.578331536




  GWAS USING LINEAR MIXED MODELS