MPD: Project measure / variable: Project1032 active_pct_d9

Project measure / variable: Project1032 active_pct_d9_control

ID, description, units	MPD:111448 active_pct_d9_control percentage of lever presses that are active (intravenous self administration), saline [%] day 9
Data set, strains	Project1032 HMDP 64 strains sex: both age: 9-15wks
Procedure	operant conditioning chamber
Ontology mappings

STRAIN COMPARISON PLOT

Dimensions Width: px Height: px

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Visualization Options Least squares means Alphabetical order Strains on X-axis Individual points

Project1032 - percentage of lever presses that are active (intravenous self administration), saline day 9

MEASURE SUMMARY

Measure Summary	Female	Male
Number of strains tested	60 strains	63 strains
Mean of the strain means	62.49 %	61.82 %
Median of the strain means	60.77 %	60.77 %
SD of the strain means	± 17.313	± 16.834
Coefficient of variation (CV)	0.2771	0.2723
Min–max range of strain means	25.4 – 100.0 %	25.8 – 100.0 %
Mean sample size per strain	2.2 mice	2.1 mice

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p value (Pr>F)
sex	1	75.7346	75.7346	0.1206	0.729
strain	35	11534.5319	329.5581	0.5247	0.9849
sex:strain	35	15938.0024	455.3715	0.725	0.8626
Residuals	117	73485.6375	628.0824

Q-Q normality assessment based on residuals

STRAIN MEANS (UNADJUSTED)

Strain	Sex	Mean	SD	N mice	SEM	CV	Min, Max	Z score
A/J	f	53.27	27.048	3	15.616	0.5078	28.0, 81.8	-0.53
A/J	m	48.35	7.7075	2	5.45	0.1594	42.9, 53.8	-0.8
AKR/J	f	60.7	15.132	2	10.7	0.2493	50.0, 71.4	-0.1
AKR/J	m	56.25	8.8388	2	6.25	0.1571	50.0, 62.5	-0.33
BALB/cByJ	f	39.5	37.637	3	21.729	0.9528	5.6, 80.0	-1.33
BALB/cByJ	m	60.07	11.494	3	6.6358	0.1913	47.1, 69.0	-0.1
BALB/cJ	f	67.3	25.938	3	14.975	0.3854	37.5, 84.8	0.28
BALB/cJ	m	56.0	29.055	4	14.527	0.5188	25.4, 94.0	-0.35
BPL/1J	f	56.1	14.991	2	10.6	0.2672	45.5, 66.7	-0.37
BPL/1J	m	37.25	18.031	2	12.75	0.4841	24.5, 50.0	-1.46
BTBR T⁺ Itpr3^tf/J	m	57.1	0.0	1	0.0	0.0	57.1, 57.1	-0.28
BXD100/RwwJ	f	58.6	0.0	1	0.0	0.0	58.6, 58.6	-0.22
BXD100/RwwJ	m	51.85	21.001	2	14.85	0.405	37.0, 66.7	-0.59
BXD11/TyJ	f	88.45	16.334	2	11.55	0.1847	76.9, 100.0	1.5
BXD11/TyJ	m	91.1	0.0	1	0.0	0.0	91.1, 91.1	1.74
BXD15/TyJ	f	53.9	0.0	1	0.0	0.0	53.9, 53.9	-0.5
BXD15/TyJ	m	75.1	17.24	3	9.9534	0.2296	64.7, 95.0	0.79
BXD1/TyJ	f	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.17
BXD1/TyJ	m	73.73	26.922	3	15.544	0.3651	46.2, 100.0	0.71
BXD21/TyJ	f	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.17
BXD21/TyJ	m	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.27
BXD28/TyJ	f	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.72
BXD28/TyJ	m	69.4	0.0	1	0.0	0.0	69.4, 69.4	0.45
BXD2/TyJ	f	40.3	23.223	3	13.408	0.5762	13.8, 57.1	-1.28
BXD2/TyJ	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.7
BXD31/TyJ	f	51.1	16.808	3	9.7043	0.3289	33.3, 66.7	-0.66
BXD31/TyJ	m	68.2	44.972	2	31.8	0.6594	36.4, 100.0	0.38
BXD32/TyJ	f	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.17
BXD32/TyJ	m	36.65	4.7376	2	3.35	0.1293	33.3, 40.0	-1.5
BXD34/TyJ	f	88.75	9.9702	2	7.05	0.1123	81.7, 95.8	1.52
BXD34/TyJ	m	61.3	8.061	2	5.7	0.1315	55.6, 67.0	-0.03
BXD38/TyJ	f	66.93	14.699	3	8.4863	0.2196	50.0, 76.4	0.26
BXD38/TyJ	m	47.933	14.012	3	8.0898	0.2923	33.6, 61.6	-0.82
BXD39/TyJ	f	33.25	9.1217	2	6.45	0.2743	26.8, 39.7	-1.69
BXD40/TyJ	f	75.1	5.2326	2	3.7	0.0697	71.4, 78.8	0.73
BXD40/TyJ	m	60.77	31.004	3	17.9	0.5102	25.0, 80.0	-0.06
BXD42/TyJ	f	43.433	36.307	3	20.962	0.8359	10.9, 82.6	-1.1
BXD42/TyJ	m	59.93	31.429	3	18.145	0.5244	27.3, 90.0	-0.11
BXD48a/RwwJ	f	61.33	12.108	3	6.9905	0.1974	53.8, 75.3	-0.07
BXD48a/RwwJ	m	54.23	24.348	3	14.057	0.4489	26.9, 73.6	-0.45
BXD50/RwwJ	f	37.45	14.92	2	10.55	0.3984	26.9, 48.0	-1.45
BXD50/RwwJ	m	67.6	0.0	1	0.0	0.0	67.6, 67.6	0.34
BXD55/RwwJ	f	90.4	0.0	1	0.0	0.0	90.4, 90.4	1.61
BXD55/RwwJ	m	55.3	52.04	2	36.8	0.9411	18.5, 92.1	-0.39
BXD56/RwwJ	f	66.7	0.0	1	0.0	0.0	66.7, 66.7	0.24
BXD56/RwwJ	m	70.3	0.0	1	0.0	0.0	70.3, 70.3	0.5
BXD60/RwwJ	f	67.1	24.183	2	17.1	0.3604	50.0, 84.2	0.27
BXD60/RwwJ	m	54.5	0.0	1	0.0	0.0	54.5, 54.5	-0.43
BXD61/RwwJ	f	62.23	13.489	3	7.7881	0.2168	50.0, 76.7	-0.02
BXD61/RwwJ	m	65.73	3.828	3	2.2101	0.0582	62.6, 70.0	0.23
BXD62/RwwJ	f	46.3	22.48	3	12.979	0.4855	22.2, 66.7	-0.94
BXD62/RwwJ	m	79.6	11.172	2	7.9	0.1404	71.7, 87.5	1.06
BXD63/RwwJ	f	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.72
BXD63/RwwJ	m	78.85	16.193	2	11.45	0.2054	67.4, 90.3	1.01
BXD65/RwwJ	f	64.23	31.0	3	17.898	0.4826	45.1, 100.0	0.1
BXD65/RwwJ	m	52.5	38.891	2	27.5	0.7408	25.0, 80.0	-0.55
BXD68/RwwJ	f	59.3	5.2326	2	3.7	0.0882	55.6, 63.0	-0.18
BXD68/RwwJ	m	70.85	5.869	2	4.15	0.0828	66.7, 75.0	0.54
BXD69/RwwJ	f	92.7	0.0	1	0.0	0.0	92.7, 92.7	1.74
BXD69/RwwJ	m	80.0	0.0	1	0.0	0.0	80.0, 80.0	1.08
BXD70/RwwJ	f	55.4	63.07	2	44.6	1.1385	10.8, 100.0	-0.41
BXD70/RwwJ	m	88.5	0.0	1	0.0	0.0	88.5, 88.5	1.59
BXD71/RwwJ	f	65.65	35.709	2	25.25	0.5439	40.4, 90.9	0.18
BXD71/RwwJ	m	47.1	0.0	1	0.0	0.0	47.1, 47.1	-0.87
BXD73a/RwwJ	f	70.4	0.0	1	0.0	0.0	70.4, 70.4	0.46
BXD73a/RwwJ	m	90.5	13.435	2	9.5	0.1485	81.0, 100.0	1.7
BXD75/RwwJ	f	82.0	0.0	1	0.0	0.0	82.0, 82.0	1.13
BXD75/RwwJ	m	68.6	0.0	1	0.0	0.0	68.6, 68.6	0.4
BXD77/RwwJ	f	50.37	45.351	3	26.183	0.9004	5.2, 95.9	-0.7
BXD77/RwwJ	m	54.07	23.07	3	13.32	0.4267	33.3, 78.9	-0.46
BXD84/RwwJ	f	53.13	31.893	3	18.413	0.6002	16.7, 76.0	-0.54
BXD84/RwwJ	m	53.0	16.545	3	9.5521	0.3122	43.1, 72.1	-0.52
BXD90/RwwJ	m	100.0	0.0	1	0.0	0.0	100.0, 100.0	2.27
BXD98/RwwJ	f	76.9	16.459	3	9.5028	0.214	57.9, 86.8	0.83
BXD98/RwwJ	m	51.73	27.83	3	16.068	0.5379	30.0, 83.1	-0.6
BXD99/RwwJ	m	77.8	0.0	1	0.0	0.0	77.8, 77.8	0.95
C3HeB/FeJ	f	44.6	10.41	3	6.0103	0.2334	33.3, 53.8	-1.03
C3HeB/FeJ	m	76.15	10.112	2	7.15	0.1328	69.0, 83.3	0.85
C3H/HeJ	f	38.65	16.051	2	11.35	0.4153	27.3, 50.0	-1.38
C3H/HeJ	m	64.43	33.57	3	19.382	0.521	33.3, 100.0	0.16
C57BL/10J	f	60.63	30.037	3	17.342	0.4954	27.3, 85.6	-0.11
C57BL/10J	m	60.53	29.66	3	17.124	0.49	37.5, 94.0	-0.08
C57BL/6J	f	81.5	23.106	3	13.341	0.2835	55.6, 100.0	1.1
C57BL/6J	m	50.5	36.273	3	20.942	0.7183	10.0, 80.0	-0.67
C57BLKS/J	f	51.83	19.515	3	11.267	0.3765	33.3, 72.2	-0.62
C57BLKS/J	m	50.0	0.0	1	0.0	0.0	50.0, 50.0	-0.7
C57BR/cdJ	f	57.63	28.925	3	16.7	0.5019	32.4, 89.2	-0.28
C57BR/cdJ	m	70.43	28.127	3	16.239	0.3993	38.2, 90.0	0.51
C57L/J	f	61.05	15.627	2	11.05	0.256	50.0, 72.1	-0.08
C57L/J	m	77.93	14.075	3	8.1262	0.1806	63.4, 91.5	0.96
C58/J	f	60.83	29.927	3	17.278	0.492	26.3, 79.2	-0.1
C58/J	m	25.8	13.294	2	9.4	0.5153	16.4, 35.2	-2.14
CBA/J	f	61.1	34.708	3	20.039	0.568	33.3, 100.0	-0.08
CBA/J	m	60.98	18.765	4	9.3826	0.3078	50.0, 88.9	-0.05
DBA/1J	f	63.85	15.768	2	11.15	0.247	52.7, 75.0	0.08
DBA/1J	m	72.23	25.455	3	14.697	0.3524	50.0, 100.0	0.62
DBA/2J	f	70.0	42.426	2	30.0	0.6061	40.0, 100.0	0.43
DBA/2J	m	56.75	33.163	2	23.45	0.5844	33.3, 80.2	-0.3
FVB/NJ	f	47.933	7.1283	3	4.1156	0.1487	40.0, 53.8	-0.84
FVB/NJ	m	26.25	25.668	2	18.15	0.9778	8.1, 44.4	-2.11
I/LnJ	f	45.65	17.466	2	12.35	0.3826	33.3, 58.0	-0.97
I/LnJ	m	71.4	36.911	2	26.1	0.517	45.3, 97.5	0.57
KK/HlJ	f	52.8	12.733	3	7.3514	0.2412	41.7, 66.7	-0.56
KK/HlJ	m	65.23	23.024	3	13.293	0.3529	40.0, 85.1	0.2
LP/J	f	90.0	0.0	1	0.0	0.0	90.0, 90.0	1.59
LP/J	m	35.0	21.213	2	15.0	0.6061	20.0, 50.0	-1.59
MA/MyJ	f	59.7	0.0	1	0.0	0.0	59.7, 59.7	-0.16
MA/MyJ	m	33.7	12.304	2	8.7	0.3651	25.0, 42.4	-1.67
MRL/MpJ	f	66.65	47.164	2	33.35	0.7076	33.3, 100.0	0.24
MRL/MpJ	m	72.2	39.315	2	27.8	0.5445	44.4, 100.0	0.62
NOD/ShiLtJ	f	25.4	15.839	2	11.2	0.6236	14.2, 36.6	-2.14
NOD/ShiLtJ	m	45.2	52.18	2	36.9	1.1545	8.3, 82.1	-0.99
NZB/BlNJ	f	68.8	12.445	2	8.8	0.1809	60.0, 77.6	0.36
NZB/BlNJ	m	90.2	0.0	1	0.0	0.0	90.2, 90.2	1.69
NZO/HlLtJ	f	50.23	8.8059	3	5.0841	0.1753	42.9, 60.0	-0.71
NZO/HlLtJ	m	76.65	9.4045	2	6.65	0.1227	70.0, 83.3	0.88
NZW/LacJ	f	87.5	17.678	2	12.5	0.202	75.0, 100.0	1.44
NZW/LacJ	m	33.3	0.0	1	0.0	0.0	33.3, 33.3	-1.69
PL/J	f	48.267	14.18	3	8.1866	0.2938	33.3, 61.5	-0.82
PL/J	m	62.3	3.2527	2	2.3	0.0522	60.0, 64.6	0.03
SJL/J	m	44.6	34.79	2	24.6	0.78	20.0, 69.2	-1.02
SM/J	f	76.63	23.002	3	13.28	0.3002	53.8, 99.8	0.82
SM/J	m	50.97	27.376	3	15.806	0.5371	22.2, 76.7	-0.64

LEAST SQUARES MEANS (MODEL-ADJUSTED)

Strain	Sex	Mean	SEM	UpperCL	LowerCL
A/J	f	53.2666666667	14.469305118	81.9223672423	24.6109660911
A/J	m	48.35	17.7212072359	83.4459223161	13.2540776839
AKR/J	f	60.7	17.7212072359	95.7959223161	25.6040776839
AKR/J	m	56.25	17.7212072359	91.3459223161	21.1540776839
BALB/cByJ	f	39.5	14.469305118	68.1557005756	10.8442994244
BALB/cByJ	m	60.0666666667	14.469305118	88.7223672423	31.4109660911
BALB/cJ	f	67.3	14.469305118	95.9557005756	38.6442994244
BALB/cJ	m	56.0	12.5307858073	80.8165646617	31.1834353383
BPL/1J	f	56.1	17.7212072359	91.1959223161	21.0040776839
BPL/1J	m	37.25	17.7212072359	72.3459223161	2.1540776839
BXD31/TyJ	f	51.1	14.469305118	79.7557005756	22.4442994244
BXD31/TyJ	m	68.2	17.7212072359	103.2959223161	33.1040776839
BXD34/TyJ	f	88.75	17.7212072359	123.8459223161	53.6540776839
BXD34/TyJ	m	61.3	17.7212072359	96.3959223161	26.2040776839
BXD38/TyJ	f	66.9333333333	14.469305118	95.5890339089	38.2776327577
BXD38/TyJ	m	47.9333333333	14.469305118	76.5890339089	19.2776327577
BXD40/TyJ	f	75.1	17.7212072359	110.1959223161	40.0040776839
BXD40/TyJ	m	60.7666666667	14.469305118	89.4223672423	32.1109660911
BXD42/TyJ	f	43.4333333333	14.469305118	72.0890339089	14.7776327577
BXD42/TyJ	m	59.9333333333	14.469305118	88.5890339089	31.2776327577
BXD48a/RwwJ	f	61.3333333333	14.469305118	89.9890339089	32.6776327577
BXD48a/RwwJ	m	54.2333333333	14.469305118	82.8890339089	25.5776327577
BXD61/RwwJ	f	62.2333333333	14.469305118	90.8890339089	33.5776327577
BXD61/RwwJ	m	65.7333333333	14.469305118	94.3890339089	37.0776327577
BXD62/RwwJ	f	46.3	14.469305118	74.9557005756	17.6442994244
BXD62/RwwJ	m	79.6	17.7212072359	114.6959223161	44.5040776839
BXD65/RwwJ	f	64.2333333333	14.469305118	92.8890339089	35.5776327577
BXD65/RwwJ	m	52.5	17.7212072359	87.5959223161	17.4040776839
BXD68/RwwJ	f	59.3	17.7212072359	94.3959223161	24.2040776839
BXD68/RwwJ	m	70.85	17.7212072359	105.9459223161	35.7540776839
BXD77/RwwJ	f	50.3666666667	14.469305118	79.0223672423	21.7109660911
BXD77/RwwJ	m	54.0666666667	14.469305118	82.7223672423	25.4109660911
BXD84/RwwJ	f	53.1333333333	14.469305118	81.7890339089	24.4776327577
BXD84/RwwJ	m	53.0	14.469305118	81.6557005756	24.3442994244
BXD98/RwwJ	f	76.9	14.469305118	105.5557005756	48.2442994244
BXD98/RwwJ	m	51.7333333333	14.469305118	80.3890339089	23.0776327577
C3HeB/FeJ	f	44.6	14.469305118	73.2557005756	15.9442994244
C3HeB/FeJ	m	76.15	17.7212072359	111.2459223161	41.0540776839
C3H/HeJ	f	38.65	17.7212072359	73.7459223161	3.5540776839
C3H/HeJ	m	64.4333333333	14.469305118	93.0890339089	35.7776327577
C57BL/10J	f	60.6333333333	14.469305118	89.2890339089	31.9776327577
C57BL/10J	m	60.5333333333	14.469305118	89.1890339089	31.8776327577
C57BL/6J	f	81.5	14.469305118	110.1557005756	52.8442994244
C57BL/6J	m	50.5	14.469305118	79.1557005756	21.8442994244
C57BR/cdJ	f	57.6333333333	14.469305118	86.2890339089	28.9776327577
C57BR/cdJ	m	70.4333333333	14.469305118	99.0890339089	41.7776327577
C57L/J	f	61.05	17.7212072359	96.1459223161	25.9540776839
C57L/J	m	77.9333333333	14.469305118	106.5890339089	49.2776327577
C58/J	f	60.8333333333	14.469305118	89.4890339089	32.1776327577
C58/J	m	25.8	17.7212072359	60.8959223161	-9.2959223161
CBA/J	f	61.1	14.469305118	89.7557005756	32.4442994244
CBA/J	m	60.975	12.5307858073	85.7915646617	36.1584353383
DBA/1J	f	63.85	17.7212072359	98.9459223161	28.7540776839
DBA/1J	m	72.2333333333	14.469305118	100.8890339089	43.5776327577
DBA/2J	f	70.0	17.7212072359	105.0959223161	34.9040776839
DBA/2J	m	56.75	17.7212072359	91.8459223161	21.6540776839
FVB/NJ	f	47.9333333333	14.469305118	76.5890339089	19.2776327577
FVB/NJ	m	26.25	17.7212072359	61.3459223161	-8.8459223161
I/LnJ	f	45.65	17.7212072359	80.7459223161	10.5540776839
I/LnJ	m	71.4	17.7212072359	106.4959223161	36.3040776839
KK/HlJ	f	52.8	14.469305118	81.4557005756	24.1442994244
KK/HlJ	m	65.2333333333	14.469305118	93.8890339089	36.5776327577
MRL/MpJ	f	66.65	17.7212072359	101.7459223161	31.5540776839
MRL/MpJ	m	72.2	17.7212072359	107.2959223161	37.1040776839
NOD/ShiLtJ	f	25.4	17.7212072359	60.4959223161	-9.6959223161
NOD/ShiLtJ	m	45.2	17.7212072359	80.2959223161	10.1040776839
NZO/HlLtJ	f	50.2333333333	14.469305118	78.8890339089	21.5776327577
NZO/HlLtJ	m	76.65	17.7212072359	111.7459223161	41.5540776839
PL/J	f	48.2666666667	14.469305118	76.9223672423	19.6109660911
PL/J	m	62.3	17.7212072359	97.3959223161	27.2040776839
SM/J	f	76.6333333333	14.469305118	105.2890339089	47.9776327577
SM/J	m	50.9666666667	14.469305118	79.6223672423	22.3109660911

LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED

Strain	Sex	Mean	SEM	UpperCL	LowerCL
A/J	both	50.8083333333	11.4389900832	73.462653775	28.1540128917
AKR/J	both	58.475	12.5307858073	83.2915646617	33.6584353383
BALB/cByJ	both	49.7833333333	10.231343768	70.04597353	29.5206931367
BALB/cJ	both	61.65	9.5705457465	80.6039643418	42.6960356582
BPL/1J	both	46.675	12.5307858073	71.4915646617	21.8584353383
BXD31/TyJ	both	59.65	11.4389900832	82.3043204417	36.9956795583
BXD34/TyJ	both	75.025	12.5307858073	99.8415646617	50.2084353383
BXD38/TyJ	both	57.4333333333	10.231343768	77.69597353	37.1706931367
BXD40/TyJ	both	67.9333333333	11.4389900832	90.587653775	45.2790128917
BXD42/TyJ	both	51.6833333333	10.231343768	71.94597353	31.4206931367
BXD48a/RwwJ	both	57.7833333333	10.231343768	78.04597353	37.5206931367
BXD61/RwwJ	both	63.9833333333	10.231343768	84.24597353	43.7206931367
BXD62/RwwJ	both	62.95	11.4389900832	85.6043204417	40.2956795583
BXD65/RwwJ	both	58.3666666667	11.4389900832	81.0209871083	35.712346225
BXD68/RwwJ	both	65.075	12.5307858073	89.8915646617	40.2584353383
BXD77/RwwJ	both	52.2166666667	10.231343768	72.4793068633	31.95402647
BXD84/RwwJ	both	53.0666666667	10.231343768	73.3293068633	32.80402647
BXD98/RwwJ	both	64.3166666667	10.231343768	84.5793068633	44.05402647
C3HeB/FeJ	both	60.375	11.4389900832	83.0293204417	37.7206795583
C3H/HeJ	both	51.5416666667	11.4389900832	74.1959871083	28.887346225
C57BL/10J	both	60.5833333333	10.231343768	80.84597353	40.3206931367
C57BL/6J	both	66.0	10.231343768	86.2626401967	45.7373598033
C57BR/cdJ	both	64.0333333333	10.231343768	84.29597353	43.7706931367
C57L/J	both	69.4916666667	11.4389900832	92.1459871083	46.837346225
C58/J	both	43.3166666667	11.4389900832	65.9709871083	20.662346225
CBA/J	both	61.0375	9.5705457465	79.9914643418	42.0835356582
DBA/1J	both	68.0416666667	11.4389900832	90.6959871083	45.387346225
DBA/2J	both	63.375	12.5307858073	88.1915646617	38.5584353383
FVB/NJ	both	37.0916666667	11.4389900832	59.7459871083	14.437346225
I/LnJ	both	58.525	12.5307858073	83.3415646617	33.7084353383
KK/HlJ	both	59.0166666667	10.231343768	79.2793068633	38.75402647
MRL/MpJ	both	69.425	12.5307858073	94.2415646617	44.6084353383
NOD/ShiLtJ	both	35.3	12.5307858073	60.1165646617	10.4834353383
NZO/HlLtJ	both	63.4416666667	11.4389900832	86.0959871083	40.787346225
PL/J	both	55.2833333333	11.4389900832	77.937653775	32.6290128917
SM/J	both	63.8	10.231343768	84.0626401967	43.5373598033

INDIVIDUAL ANIMAL VALUES

Click here to view individual animal values

GWAS USING LINEAR MIXED MODELS