Project measure / variable:   Project1032   inactive_d9_cocaine

ID, description, units MPD:111510   inactive_d9_cocaine   number of inactive lever presses (intravenous self administration), cocaine   [n]  day 9  
cocaine study
Data set, strains Project1032   HMDP   65 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of inactive lever presses (intravenous self administration), cocaine day 9



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested57 strains60 strains
Mean of the strain means14.433   n 23.985   n
Median of the strain means6.0   n 7.0   n
SD of the strain means± 24.094 ± 51.03
Coefficient of variation (CV)1.6694 2.1274
Min–max range of strain means1.0   –   112.0   n 1.0   –   325.0   n
Mean sample size per strain1.8   mice 1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 93.6889 93.6889 0.0637 0.8016
strain 20 40224.6941 2011.2347 1.3665 0.1737
sex:strain 20 32269.9623 1613.4981 1.0963 0.3758
Residuals 63 92722.4167 1471.7844


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 19.0 24.042   2   17.0 1.2653 2.0, 36.0 -0.1
A/J f 9.5 9.1924   2   6.5 0.9676 3.0, 16.0 -0.2
A/J m 8.3333 10.214   3 5.8973 1.2257 1.0, 20.0 -0.31
AKR/J f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.54
AKR/J m 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.43
BALB/cByJ f 4.3333 4.1633   3 2.4037 0.9608 1.0, 9.0 -0.42
BALB/cByJ m 6.0 5.6569   2   4.0 0.9428 2.0, 10.0 -0.35
BALB/cJ f 7.6667 11.547   3 6.6667 1.5061 1.0, 21.0 -0.28
BALB/cJ m 8.0 5.6569   2   4.0 0.7071 4.0, 12.0 -0.31
BPL/1J f 103.7 88.46   3 51.07 0.8533 3.0, 169.0 3.7
BPL/1J m 12.0 8.7178   3 5.0332 0.7265 2.0, 18.0 -0.23
BTBR T+ Itpr3tf/J f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.54
BTBR T+ Itpr3tf/J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.45
BXD100/RwwJ f 7.0 8.4853   2   6.0 1.2122 1.0, 13.0 -0.31
BXD100/RwwJ m 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.29
BXD11/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.56
BXD11/TyJ m 325.0 0.0   1   0.0 0.0 325.0, 325.0 5.9
BXD15/TyJ f 9.0 11.314   2   8.0 1.2571 1.0, 17.0 -0.23
BXD15/TyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.45
BXD1/TyJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.41
BXD21/TyJ f 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.02
BXD21/TyJ m 19.5 24.749   2   17.5 1.2692 2.0, 37.0 -0.09
BXD28/TyJ f 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.23
BXD2/TyJ f 61.33 42.852   3 24.741 0.6987 22.0, 107.0 1.95
BXD2/TyJ m 36.0 45.255   2   32.0 1.2571 4.0, 68.0 0.24
BXD31/TyJ f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.31
BXD31/TyJ m 9.0 4.9666   4 2.4833 0.5518 2.0, 13.0 -0.29
BXD32/TyJ f 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.5
BXD32/TyJ m 4.5 3.5355   2   2.5 0.7857 2.0, 7.0 -0.38
BXD34/TyJ f 3.0 2.8284   2   2.0 0.9428 1.0, 5.0 -0.47
BXD34/TyJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.35
BXD38/TyJ f 6.0 0.0   3 0.0 0.0 6.0, 6.0 -0.35
BXD38/TyJ m 25.0 37.242   3 21.502 1.4897 3.0, 68.0 0.02
BXD39/TyJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.35
BXD39/TyJ m 5.5 6.364   2   4.5 1.1571 1.0, 10.0 -0.36
BXD40/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.56
BXD40/TyJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.43
BXD42/TyJ f 16.5 19.092   2   13.5 1.1571 3.0, 30.0 0.09
BXD42/TyJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.43
BXD48a/RwwJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.47
BXD48a/RwwJ m 33.333 37.581   3 21.697 1.1274 2.0, 75.0 0.18
BXD50/RwwJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.39
BXD50/RwwJ m 10.0 11.314   2   8.0 1.1314 2.0, 18.0 -0.27
BXD55/RwwJ f 16.0 0.0   1   0.0 0.0 16.0, 16.0 0.07
BXD55/RwwJ m 35.0 0.0   1   0.0 0.0 35.0, 35.0 0.22
BXD56/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.45
BXD60/RwwJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.33
BXD61/RwwJ f 6.5 0.70711   2   0.5 0.1088 6.0, 7.0 -0.33
BXD62/RwwJ f 3.0 2.6458   3 1.5275 0.8819 1.0, 6.0 -0.47
BXD62/RwwJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.35
BXD63/RwwJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.37
BXD65/RwwJ f 13.5 6.364   2   4.5 0.4714 9.0, 18.0 -0.04
BXD65/RwwJ m 5.0 1.4142   2   1.0 0.2828 4.0, 6.0 -0.37
BXD68/RwwJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 1.19
BXD68/RwwJ m 70.0 0.0   1   0.0 0.0 70.0, 70.0 0.9
BXD69/RwwJ f 112.0 142.8   2   101.0 1.2753 11.0, 213.0 4.05
BXD70/RwwJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.39
BXD70/RwwJ m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.39
BXD71/RwwJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.27
BXD71/RwwJ m 34.0 0.0   1   0.0 0.0 34.0, 34.0 0.2
BXD73a/RwwJ f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.18
BXD73a/RwwJ m 178.0 0.0   1   0.0 0.0 178.0, 178.0 3.02
BXD75/RwwJ f 15.0 0.0   1   0.0 0.0 15.0, 15.0 0.02
BXD75/RwwJ m 34.0 25.456   2   18.0 0.7487 16.0, 52.0 0.2
BXD77/RwwJ f 5.5 6.364   2   4.5 1.1571 1.0, 10.0 -0.37
BXD77/RwwJ m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.08
BXD84/RwwJ f 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.5
BXD84/RwwJ m 8.0 7.5498   3 4.3589 0.9437 1.0, 16.0 -0.31
BXD90/RwwJ m 8.5 7.7782   2   5.5 0.9151 3.0, 14.0 -0.3
BXD98/RwwJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.47
BXD98/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.45
BXD99/RwwJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.39
BXD99/RwwJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.35
C3HeB/FeJ f 14.0 15.556   2   11.0 1.1112 3.0, 25.0 -0.02
C3HeB/FeJ m 3.0 2.8284   2   2.0 0.9428 1.0, 5.0 -0.41
C3H/HeJ f 1.3333 0.57735   3 0.33333 0.433 1.0, 2.0 -0.54
C3H/HeJ m 9.0 11.314   2   8.0 1.2571 1.0, 17.0 -0.29
C57BL/10J f 7.0 6.245   3 3.6056 0.8921 2.0, 14.0 -0.31
C57BL/10J m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.44
C57BL/6J f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.52
C57BL/6J m 1.6667 1.1547   3 0.66667 0.6928 1.0, 3.0 -0.44
C57BLKS/J f 78.33 82.08   3 47.39 1.0478 5.0, 167.0 2.65
C57BLKS/J m 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.43
C57BR/cdJ f 9.0 9.6437   3 5.5678 1.0715 2.0, 20.0 -0.23
C57BR/cdJ m 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.42
C57L/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.56
C57L/J m 10.667 6.6583   3 3.8442 0.6242 5.0, 18.0 -0.26
C58/J f 6.5 3.5355   2   2.5 0.5439 4.0, 9.0 -0.33
C58/J m 3.0 2.0   3 1.1547 0.6667 1.0, 5.0 -0.41
CBA/J f 4.0 1.7321   3 1.0 0.433 3.0, 6.0 -0.43
CBA/J m 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.45
DBA/1J f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.47
DBA/1J m 2.0 0.0   2   0.0 0.0 2.0, 2.0 -0.43
DBA/2J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.45
FVB/NJ f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.44
FVB/NJ m 6.0 4.2426   2   3.0 0.7071 3.0, 9.0 -0.35
I/LnJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.56
I/LnJ m 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.04
KK/HlJ f 4.5 4.9497   2   3.5 1.0999 1.0, 8.0 -0.41
KK/HlJ m 45.0 31.113   2   22.0 0.6914 23.0, 67.0 0.41
LP/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.56
LP/J m 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.45
MA/MyJ f 70.67 110.4   3 63.73 1.5621 2.0, 198.0 2.33
MRL/MpJ f 4.5 3.5355   2   2.5 0.7857 2.0, 7.0 -0.41
MRL/MpJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.43
NOD/ShiLtJ f 30.667 17.214   3 9.9387 0.5613 17.0, 50.0 0.67
NOD/ShiLtJ m 60.33 55.3   3 31.929 0.9166 2.0, 112.0 0.71
NZB/BlNJ m 7.0 7.0711   2   5.0 1.0102 2.0, 12.0 -0.33
NZO/HlLtJ f 5.0 4.2426   2   3.0 0.8485 2.0, 8.0 -0.39
NZO/HlLtJ m 87.0 147.2   3 85.0 1.6922 2.0, 257.0 1.23
NZW/LacJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.39
NZW/LacJ m 32.5 44.548   2   31.5 1.3707 1.0, 64.0 0.17
PL/J f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.47
PL/J m 147.0 62.55   3 36.116 0.4255 75.0, 188.0 2.41
SJL/J f 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.52
SM/J f 16.667 17.01   3 9.8206 1.0206 4.0, 36.0 0.09
SM/J m 22.25 24.459   4 12.23 1.0993 1.0, 49.0 -0.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 9.5 27.1273330014 63.7096493471 -44.7096493471
A/J m 8.3333333333 22.1493746453 52.5953266785 -35.9286600119
AKR/J f 1.5 27.1273330014 55.7096493471 -52.7096493471
AKR/J m 2.0 27.1273330014 56.2096493471 -52.2096493471
BALB/cByJ f 4.3333333333 22.1493746453 48.5953266785 -39.9286600119
BALB/cByJ m 6.0 27.1273330014 60.2096493471 -48.2096493471
BALB/cJ f 7.6666666667 22.1493746453 51.9286600119 -36.5953266785
BALB/cJ m 8.0 27.1273330014 62.2096493471 -46.2096493471
BPL/1J f 103.6666666667 22.1493746453 147.9286600119 59.4046733215
BPL/1J m 12.0 22.1493746453 56.2619933452 -32.2619933452
BXD2/TyJ f 61.3333333333 22.1493746453 105.5953266785 17.0713399881
BXD2/TyJ m 36.0 27.1273330014 90.2096493471 -18.2096493471
BXD32/TyJ f 2.5 27.1273330014 56.7096493471 -51.7096493471
BXD32/TyJ m 4.5 27.1273330014 58.7096493471 -49.7096493471
BXD38/TyJ f 6.0 22.1493746453 50.2619933452 -38.2619933452
BXD38/TyJ m 25.0 22.1493746453 69.2619933452 -19.2619933452
BXD65/RwwJ f 13.5 27.1273330014 67.7096493471 -40.7096493471
BXD65/RwwJ m 5.0 27.1273330014 59.2096493471 -49.2096493471
BXD84/RwwJ f 2.5 27.1273330014 56.7096493471 -51.7096493471
BXD84/RwwJ m 8.0 22.1493746453 52.2619933452 -36.2619933452
C3HeB/FeJ f 14.0 27.1273330014 68.2096493471 -40.2096493471
C3HeB/FeJ m 3.0 27.1273330014 57.2096493471 -51.2096493471
C3H/HeJ f 1.3333333333 22.1493746453 45.5953266785 -42.9286600119
C3H/HeJ m 9.0 27.1273330014 63.2096493471 -45.2096493471
C57BL/10J f 7.0 22.1493746453 51.2619933452 -37.2619933452
C57BL/10J m 1.5 27.1273330014 55.7096493471 -52.7096493471
C57BLKS/J f 78.3333333333 22.1493746453 122.5953266785 34.0713399881
C57BLKS/J m 2.0 27.1273330014 56.2096493471 -52.2096493471
C57BR/cdJ f 9.0 22.1493746453 53.2619933452 -35.2619933452
C57BR/cdJ m 2.5 27.1273330014 56.7096493471 -51.7096493471
C58/J f 6.5 27.1273330014 60.7096493471 -47.7096493471
C58/J m 3.0 22.1493746453 47.2619933452 -41.2619933452
CBA/J f 4.0 22.1493746453 48.2619933452 -40.2619933452
CBA/J m 1.0 27.1273330014 55.2096493471 -53.2096493471
KK/HlJ f 4.5 27.1273330014 58.7096493471 -49.7096493471
KK/HlJ m 45.0 27.1273330014 99.2096493471 -9.2096493471
NOD/ShiLtJ f 30.6666666667 22.1493746453 74.9286600119 -13.5953266785
NOD/ShiLtJ m 60.3333333333 22.1493746453 104.5953266785 16.0713399881
NZO/HlLtJ f 5.0 27.1273330014 59.2096493471 -49.2096493471
NZO/HlLtJ m 87.0 22.1493746453 131.2619933452 42.7380066548
SM/J f 16.6666666667 22.1493746453 60.9286600119 -27.5953266785
SM/J m 22.25 19.1819211208 60.5820106591 -16.0820106591


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 8.9166666667 17.5106181569 43.9088448542 -26.0755115208
AKR/J both 1.75 19.1819211208 40.0820106591 -36.5820106591
BALB/cByJ both 5.1666666667 17.5106181569 40.1588448542 -29.8255115208
BALB/cJ both 7.8333333333 17.5106181569 42.8255115208 -27.1588448542
BPL/1J both 57.8333333333 15.6619730107 89.1312889766 26.5353776901
BXD2/TyJ both 48.6666666667 17.5106181569 83.6588448542 13.6744884792
BXD32/TyJ both 3.5 19.1819211208 41.8320106591 -34.8320106591
BXD38/TyJ both 15.5 15.6619730107 46.7979556432 -15.7979556432
BXD65/RwwJ both 9.25 19.1819211208 47.5820106591 -29.0820106591
BXD84/RwwJ both 5.25 17.5106181569 40.2421781875 -29.7421781875
C3HeB/FeJ both 8.5 19.1819211208 46.8320106591 -29.8320106591
C3H/HeJ both 5.1666666667 17.5106181569 40.1588448542 -29.8255115208
C57BL/10J both 4.25 17.5106181569 39.2421781875 -30.7421781875
C57BLKS/J both 40.1666666667 17.5106181569 75.1588448542 5.1744884792
C57BR/cdJ both 5.75 17.5106181569 40.7421781875 -29.2421781875
C58/J both 4.75 17.5106181569 39.7421781875 -30.2421781875
CBA/J both 2.5 17.5106181569 37.4921781875 -32.4921781875
KK/HlJ both 24.75 19.1819211208 63.0820106591 -13.5820106591
NOD/ShiLtJ both 45.5 15.6619730107 76.7979556432 14.2020443568
NZO/HlLtJ both 46.0 17.5106181569 80.9921781875 11.0078218125
SM/J both 19.4583333333 14.6504342518 48.7348900642 -9.8182233975




  GWAS USING LINEAR MIXED MODELS