Project measure / variable:   Project1032   inactive_d5_cocaine

ID, description, units MPD:111506   inactive_d5_cocaine   number of inactive lever presses (intravenous self administration), cocaine   [n]  day 5  
cocaine study
Data set, strains Project1032   HMDP   62 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of inactive lever presses (intravenous self administration), cocaine day 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested57 strains59 strains
Mean of the strain means19.319   n 21.191   n
Median of the strain means5.0   n 6.0   n
SD of the strain means± 45.706 ± 54.31
Coefficient of variation (CV)2.3658 2.5627
Min–max range of strain means1.0   –   316.7   n 1.0   –   295.0   n
Mean sample size per strain1.9   mice 2.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0312 0.0312 0.0 0.9988
strain 23 289787.0034 12599.4349 0.8535 0.6561
sex:strain 23 281669.9236 12246.5184 0.8296 0.6856
Residuals 80 1180961.9167 14762.024


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
129S1/SvImJ m 16.5 21.92   2   15.5 1.3285 1.0, 32.0 -0.09
A/J f 11.667 10.97   3 6.3333 0.9403 3.0, 24.0 -0.17
A/J m 4.0 2.8284   2   2.0 0.7071 2.0, 6.0 -0.32
AKR/J f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.31
AKR/J m 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.33
BALB/cByJ f 5.0 2.6458   3 1.5275 0.5292 3.0, 8.0 -0.31
BALB/cByJ m 8.3333 8.5049   3 4.9103 1.0206 2.0, 18.0 -0.24
BALB/cJ f 131.0 182.4   2   129.0 1.3926 2.0, 260.0 2.44
BALB/cJ m 16.667 23.756   3 13.715 1.4253 1.0, 44.0 -0.08
BPL/1J f 53.33 68.31   3 39.439 1.2808 9.0, 132.0 0.74
BPL/1J m 32.0 28.16   3 16.258 0.88 11.0, 64.0 0.2
BTBR T+ Itpr3tf/J f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.34
BTBR T+ Itpr3tf/J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.37
BXD100/RwwJ f 8.0 8.4853   2   6.0 1.0607 2.0, 14.0 -0.25
BXD100/RwwJ m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.02
BXD11/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
BXD11/TyJ m 279.0 0.0   1   0.0 0.0 279.0, 279.0 4.75
BXD15/TyJ f 13.333 15.503   3 8.9505 1.1627 2.0, 31.0 -0.13
BXD1/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
BXD1/TyJ m 5.6667 5.5076   3 3.1798 0.9719 2.0, 12.0 -0.29
BXD21/TyJ f 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.16
BXD21/TyJ m 4.0 1.4142   2   1.0 0.3536 3.0, 5.0 -0.32
BXD2/TyJ f 17.333 14.978   3 8.6474 0.8641 5.0, 34.0 -0.04
BXD2/TyJ m 295.0 500.6   3 289.0 1.6968 4.0, 873.0 5.04
BXD31/TyJ f 4.3333 4.0415   3 2.3333 0.9326 2.0, 9.0 -0.33
BXD31/TyJ m 8.0 4.899   4 2.4495 0.6124 4.0, 14.0 -0.24
BXD32/TyJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.36
BXD32/TyJ m 7.6667 7.6376   3 4.4096 0.9962 1.0, 16.0 -0.25
BXD34/TyJ f 27.5 37.477   2   26.5 1.3628 1.0, 54.0 0.18
BXD34/TyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.37
BXD38/TyJ f 7.3333 5.5076   3 3.1798 0.751 2.0, 13.0 -0.26
BXD38/TyJ m 144.7 242.8   3 140.2 1.6783 2.0, 425.0 2.27
BXD39/TyJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.31
BXD39/TyJ m 5.0 4.2426   2   3.0 0.8485 2.0, 8.0 -0.3
BXD40/TyJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.4
BXD40/TyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.37
BXD42/TyJ f 49.5 51.62   2   36.5 1.0428 13.0, 86.0 0.66
BXD42/TyJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.24
BXD48a/RwwJ f 1.6667 0.57735   3 0.33333 0.3464 1.0, 2.0 -0.39
BXD48a/RwwJ m 29.5 4.9497   2   3.5 0.1678 26.0, 33.0 0.15
BXD50/RwwJ m 9.5 4.9497   2   3.5 0.521 6.0, 13.0 -0.22
BXD55/RwwJ f 14.0 16.971   2   12.0 1.2122 2.0, 26.0 -0.12
BXD55/RwwJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.24
BXD56/RwwJ m 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.37
BXD60/RwwJ m 4.5 3.5355   2   2.5 0.7857 2.0, 7.0 -0.31
BXD61/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.38
BXD61/RwwJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.35
BXD62/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.38
BXD62/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.37
BXD65/RwwJ f 9.0 5.6569   2   4.0 0.6285 5.0, 13.0 -0.23
BXD65/RwwJ m 11.0 12.166   3 7.0238 1.106 3.0, 25.0 -0.19
BXD68/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.37
BXD69/RwwJ f 61.0 84.85   2   60.0 1.391 1.0, 121.0 0.91
BXD70/RwwJ m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.36
BXD71/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
BXD71/RwwJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.11
BXD73a/RwwJ f 37.5 47.376   2   33.5 1.2634 4.0, 71.0 0.4
BXD73a/RwwJ m 49.0 0.0   1   0.0 0.0 49.0, 49.0 0.51
BXD75/RwwJ f 48.0 0.0   1   0.0 0.0 48.0, 48.0 0.63
BXD75/RwwJ m 4.0 1.4142   2   1.0 0.3536 3.0, 5.0 -0.32
BXD77/RwwJ f 2.6667 2.8868   3 1.6667 1.0825 1.0, 6.0 -0.36
BXD77/RwwJ m 3.5 3.5355   2   2.5 1.0102 1.0, 6.0 -0.33
BXD84/RwwJ f 5.0 4.2426   2   3.0 0.8485 2.0, 8.0 -0.31
BXD84/RwwJ m 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.34
BXD90/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
BXD90/RwwJ m 22.0 0.0   1   0.0 0.0 22.0, 22.0 0.01
BXD98/RwwJ f 17.5 21.92   2   15.5 1.2526 2.0, 33.0 -0.04
BXD98/RwwJ m 5.3333 7.5056   3 4.3333 1.4073 1.0, 14.0 -0.29
BXD99/RwwJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.05
BXD99/RwwJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.33
C3HeB/FeJ f 15.0 19.799   2   14.0 1.3199 1.0, 29.0 -0.09
C3HeB/FeJ m 2.0 0.0   2   0.0 0.0 2.0, 2.0 -0.35
C3H/HeJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.38
C3H/HeJ m 5.5 4.9497   2   3.5 0.9 2.0, 9.0 -0.29
C57BL/10J f 28.333 43.89   3 25.34 1.5491 2.0, 79.0 0.2
C57BL/10J m 40.0 52.33   2   37.0 1.3081 3.0, 77.0 0.35
C57BL/6J f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.31
C57BL/6J m 2.6667 2.0817   3 1.2019 0.7806 1.0, 5.0 -0.34
C57BLKS/J f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.31
C57BLKS/J m 6.0 6.245   3 3.6056 1.0408 1.0, 13.0 -0.28
C57BR/cdJ f 13.0 8.7178   3 5.0332 0.6706 7.0, 23.0 -0.14
C57BR/cdJ m 1.3333 0.57735   3 0.33333 0.433 1.0, 2.0 -0.37
C57L/J f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.36
C57L/J m 5.0 3.4641   3 2.0 0.6928 1.0, 7.0 -0.3
C58/J f 17.5 23.335   2   16.5 1.3334 1.0, 34.0 -0.04
C58/J m 7.6667 2.0817   3 1.2019 0.2715 6.0, 10.0 -0.25
CBA/J f 3.0 1.0   3 0.57735 0.3333 2.0, 4.0 -0.36
CBA/J m 2.3333 0.57735   3 0.33333 0.2474 2.0, 3.0 -0.35
DBA/1J f 2.0 0.0   2   0.0 0.0 2.0, 2.0 -0.38
DBA/1J m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.35
DBA/2J f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.39
FVB/NJ f 11.0 12.728   2   9.0 1.1571 2.0, 20.0 -0.18
FVB/NJ m 12.0 15.556   2   11.0 1.2964 1.0, 23.0 -0.17
I/LnJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.38
I/LnJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.28
KK/HlJ f 1.6667 1.1547   3 0.66667 0.6928 1.0, 3.0 -0.39
KK/HlJ m 11.0 7.8102   3 4.5092 0.71 6.0, 20.0 -0.19
LP/J f 6.5 7.7782   2   5.5 1.1966 1.0, 12.0 -0.28
LP/J m 7.5 3.5355   2   2.5 0.4714 5.0, 10.0 -0.25
MA/MyJ f 316.7 495.3   3 286.0 1.5642 8.0, 888.0 6.51
MA/MyJ m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.36
MRL/MpJ f 9.6667 13.317   3 7.6884 1.3776 1.0, 25.0 -0.21
MRL/MpJ m 6.5 3.5355   2   2.5 0.5439 4.0, 9.0 -0.27
NOD/ShiLtJ f 58.67 62.29   3 35.964 1.0618 15.0, 130.0 0.86
NOD/ShiLtJ m 46.0 57.71   3 33.322 1.2547 5.0, 112.0 0.46
NZB/BlNJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
NZB/BlNJ m 3.0 1.7321   3 1.0 0.5774 2.0, 5.0 -0.33
NZO/HlLtJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
NZO/HlLtJ m 10.0 11.269   3 6.5064 1.1269 3.0, 23.0 -0.21
NZW/LacJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.36
NZW/LacJ m 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.34
PL/J f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.31
PL/J m 20.667 21.079   3 12.17 1.02 8.0, 45.0 -0.01
SM/J f 9.0 4.5826   3 2.6458 0.5092 5.0, 14.0 -0.23
SM/J m 14.75 16.029   4 8.0143 1.0867 2.0, 38.0 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 11.6666666667 70.147520646 151.2646815959 -127.9313482626
A/J m 4.0 85.912816152 174.971952841 -166.971952841
BALB/cByJ f 5.0 70.147520646 144.5980149293 -134.5980149293
BALB/cByJ m 8.3333333333 70.147520646 147.9313482626 -131.2646815959
BALB/cJ f 131.0 85.912816152 301.971952841 -39.971952841
BALB/cJ m 16.6666666667 70.147520646 156.2646815959 -122.9313482626
BPL/1J f 53.3333333333 70.147520646 192.9313482626 -86.2646815959
BPL/1J m 32.0 70.147520646 171.5980149292 -107.5980149292
BXD2/TyJ f 17.3333333333 70.147520646 156.9313482626 -122.2646815959
BXD2/TyJ m 295.0 70.147520646 434.5980149292 155.4019850707
BXD31/TyJ f 4.3333333333 70.147520646 143.9313482626 -135.2646815959
BXD31/TyJ m 8.0 60.7495348919 128.8954272466 -112.8954272466
BXD38/TyJ f 7.3333333333 70.147520646 146.9313482626 -132.2646815959
BXD38/TyJ m 144.6666666667 70.147520646 284.2646815959 5.0686517374
BXD48a/RwwJ f 1.6666666667 70.147520646 141.2646815959 -137.9313482626
BXD48a/RwwJ m 29.5 85.912816152 200.471952841 -141.471952841
BXD65/RwwJ f 9.0 85.912816152 179.971952841 -161.971952841
BXD65/RwwJ m 11.0 70.147520646 150.5980149293 -128.5980149293
BXD77/RwwJ f 2.6666666667 70.147520646 142.2646815959 -136.9313482626
BXD77/RwwJ m 3.5 85.912816152 174.471952841 -167.471952841
BXD84/RwwJ f 5.0 85.912816152 175.971952841 -165.971952841
BXD84/RwwJ m 2.5 85.912816152 173.471952841 -168.471952841
BXD98/RwwJ f 17.5 85.912816152 188.471952841 -153.471952841
BXD98/RwwJ m 5.3333333333 70.147520646 144.9313482626 -134.2646815959
C3HeB/FeJ f 15.0 85.912816152 185.971952841 -155.971952841
C3HeB/FeJ m 2.0 85.912816152 172.971952841 -168.971952841
C57BL/10J f 28.3333333333 70.147520646 167.9313482626 -111.2646815959
C57BL/10J m 40.0 85.912816152 210.971952841 -130.971952841
C57BR/cdJ f 13.0 70.147520646 152.5980149292 -126.5980149292
C57BR/cdJ m 1.3333333333 70.147520646 140.9313482626 -138.2646815959
C58/J f 17.5 85.912816152 188.471952841 -153.471952841
C58/J m 7.6666666667 70.147520646 147.2646815959 -131.9313482626
CBA/J f 3.0 70.147520646 142.5980149293 -136.5980149293
CBA/J m 2.3333333333 70.147520646 141.9313482626 -137.2646815959
FVB/NJ f 11.0 85.912816152 181.971952841 -159.971952841
FVB/NJ m 12.0 85.912816152 182.971952841 -158.971952841
KK/HlJ f 1.6666666667 70.147520646 141.2646815959 -137.9313482626
KK/HlJ m 11.0 70.147520646 150.5980149292 -128.5980149292
LP/J f 6.5 85.912816152 177.471952841 -164.471952841
LP/J m 7.5 85.912816152 178.471952841 -163.471952841
MA/MyJ f 316.6666666667 70.147520646 456.2646815959 177.0686517374
MA/MyJ m 1.5 85.912816152 172.471952841 -169.471952841
MRL/MpJ f 9.6666666667 70.147520646 149.2646815959 -129.9313482626
MRL/MpJ m 6.5 85.912816152 177.471952841 -164.471952841
NOD/ShiLtJ f 58.6666666667 70.147520646 198.2646815959 -80.9313482626
NOD/ShiLtJ m 46.0 70.147520646 185.5980149292 -93.5980149292
SM/J f 9.0 70.147520646 148.5980149292 -130.5980149292
SM/J m 14.75 60.7495348919 135.6454272466 -106.1454272466


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 7.8333333333 55.4564843637 118.195254337 -102.5285876703
BALB/cByJ both 6.6666666667 49.6017875322 105.3773696633 -92.04403633
BALB/cJ both 73.8333333333 55.4564843637 184.195254337 -36.5285876703
BPL/1J both 42.6666666667 49.6017875322 141.3773696633 -56.04403633
BXD2/TyJ both 156.1666666667 49.6017875322 254.8773696633 57.45596367
BXD31/TyJ both 6.1666666667 46.3982236793 98.5020744219 -86.1687410886
BXD38/TyJ both 76.0 49.6017875322 174.7107029967 -22.7107029967
BXD48a/RwwJ both 15.5833333333 55.4564843637 125.945254337 -94.7785876703
BXD65/RwwJ both 10.0 55.4564843637 120.3619210037 -100.3619210037
BXD77/RwwJ both 3.0833333333 55.4564843637 113.445254337 -107.2785876703
BXD84/RwwJ both 3.75 60.7495348919 124.6454272466 -117.1454272466
BXD98/RwwJ both 11.4166666667 55.4564843637 121.7785876703 -98.945254337
C3HeB/FeJ both 8.5 60.7495348919 129.3954272466 -112.3954272466
C57BL/10J both 34.1666666667 55.4564843637 144.5285876703 -76.195254337
C57BR/cdJ both 7.1666666667 49.6017875322 105.8773696633 -91.54403633
C58/J both 12.5833333333 55.4564843637 122.945254337 -97.7785876703
CBA/J both 2.6666666667 49.6017875322 101.3773696633 -96.04403633
FVB/NJ both 11.5 60.7495348919 132.3954272466 -109.3954272466
KK/HlJ both 6.3333333333 49.6017875322 105.04403633 -92.3773696633
LP/J both 7.0 60.7495348919 127.8954272466 -113.8954272466
MA/MyJ both 159.0833333333 55.4564843637 269.445254337 48.7214123297
MRL/MpJ both 8.0833333333 55.4564843637 118.445254337 -102.2785876703
NOD/ShiLtJ both 52.3333333333 49.6017875322 151.04403633 -46.3773696633
SM/J both 11.875 46.3982236793 104.2104077553 -80.4604077553




  GWAS USING LINEAR MIXED MODELS