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Project measure / variable:   Project1032   infusions_d6_cocaine

ID, description, units MPD:111429   infusions_d6_cocaine   number of infusions earned (intravenous self administration), cocaine   [n]  day 6  
cocaine study
Data set, strains Project1032   HMDP   64 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of infusions earned (intravenous self administration), cocaine day 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested60 strains60 strains
Mean of the strain means24.499   n 26.904   n
Median of the strain means23.833   n 26.834   n
SD of the strain means± 16.955 ± 13.157
Coefficient of variation (CV)0.6921 0.489
Min–max range of strain means1.0   –   57.0   n 1.0   –   57.0   n
Mean sample size per strain2.2   mice 2.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 20.4875 20.4875 0.083 0.7738
strain 29 16064.8454 553.9602 2.2451 0.0014
sex:strain 29 9557.8279 329.5803 1.3357 0.1444
Residuals 110 27141.3333 246.7394


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 47.5 13.435   2   9.5 0.2828 38.0, 57.0 1.57
129X1/SvJ f 6.5 7.7782   2   5.5 1.1966 1.0, 12.0 -1.06
A/J f 20.333 22.368   3 12.914 1.1001 5.0, 46.0 -0.25
A/J m 1.6667 0.57735   3 0.33333 0.3464 1.0, 2.0 -1.92
AKR/J f 5.0 6.0828   3 3.5119 1.2166 1.0, 12.0 -1.15
AKR/J m 21.0 4.2426   2   3.0 0.202 18.0, 24.0 -0.45
BALB/cByJ f 30.0 21.166   3 12.22 0.7055 14.0, 54.0 0.32
BALB/cByJ m 22.667 4.7258   3 2.7285 0.2085 19.0, 28.0 -0.32
BALB/cJ f 24.333 20.599   3 11.893 0.8465 1.0, 40.0 -0.01
BALB/cJ m 26.667 33.201   3 19.169 1.2451 7.0, 65.0 -0.02
BPL/1J f 44.333 22.723   3 13.119 0.5125 20.0, 65.0 1.17
BPL/1J m 15.0 13.892   3 8.0208 0.9262 6.0, 31.0 -0.9
BTBR T+ Itpr3tf/J f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -1.03
BTBR T+ Itpr3tf/J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.97
BXD100/RwwJ f 8.0 1.4142   2   1.0 0.1768 7.0, 9.0 -0.97
BXD100/RwwJ m 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.22
BXD11/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.39
BXD11/TyJ m 12.5 16.263   2   11.5 1.3011 1.0, 24.0 -1.09
BXD15/TyJ f 51.0 13.115   3 7.5719 0.2572 39.0, 65.0 1.56
BXD15/TyJ m 32.0 0.0   1   0.0 0.0 32.0, 32.0 0.39
BXD1/TyJ f 42.0 0.0   1   0.0 0.0 42.0, 42.0 1.03
BXD1/TyJ m 34.333 12.342   3 7.1259 0.3595 24.0, 48.0 0.56
BXD21/TyJ f 40.0 0.0   1   0.0 0.0 40.0, 40.0 0.91
BXD21/TyJ m 53.0 16.971   2   12.0 0.3202 41.0, 65.0 1.98
BXD2/TyJ f 21.667 15.144   3 8.7433 0.6989 11.0, 39.0 -0.17
BXD2/TyJ m 51.33 11.846   3 6.8394 0.2308 44.0, 65.0 1.86
BXD31/TyJ f 39.0 15.588   3 9.0 0.3997 21.0, 48.0 0.86
BXD31/TyJ m 23.5 11.846   4 5.9231 0.5041 6.0, 32.0 -0.26
BXD32/TyJ f 57.0 0.0   1   0.0 0.0 57.0, 57.0 1.92
BXD32/TyJ m 20.0 18.0   3 10.392 0.9 2.0, 38.0 -0.52
BXD34/TyJ f 18.5 7.7782   2   5.5 0.4204 13.0, 24.0 -0.35
BXD38/TyJ f 35.0 13.528   3 7.8102 0.3865 21.0, 48.0 0.62
BXD38/TyJ m 45.0 7.9373   3 4.5826 0.1764 39.0, 54.0 1.38
BXD39/TyJ m 12.667 11.719   3 6.7659 0.9252 4.0, 26.0 -1.08
BXD40/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.39
BXD40/TyJ m 25.5 34.648   2   24.5 1.3588 1.0, 50.0 -0.11
BXD42/TyJ f 40.5 17.678   2   12.5 0.4365 28.0, 53.0 0.94
BXD42/TyJ m 46.667 8.0208   3 4.6308 0.1719 39.0, 55.0 1.5
BXD48a/RwwJ f 25.0 20.881   3 12.055 0.8352 1.0, 39.0 0.03
BXD48a/RwwJ m 30.667 5.0332   3 2.9059 0.1641 26.0, 36.0 0.29
BXD50/RwwJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.21
BXD50/RwwJ m 21.5 13.435   2   9.5 0.6249 12.0, 31.0 -0.41
BXD55/RwwJ f 50.0 21.213   2   15.0 0.4243 35.0, 65.0 1.5
BXD55/RwwJ m 30.0 0.0   1   0.0 0.0 30.0, 30.0 0.24
BXD60/RwwJ f 45.0 0.0   1   0.0 0.0 45.0, 45.0 1.21
BXD60/RwwJ m 39.0 12.728   2   9.0 0.3264 30.0, 48.0 0.92
BXD61/RwwJ f 16.0 16.093   3 9.2916 1.0058 1.0, 33.0 -0.5
BXD61/RwwJ m 39.0 0.0   1   0.0 0.0 39.0, 39.0 0.92
BXD62/RwwJ f 10.0 8.4853   2   6.0 0.8485 4.0, 16.0 -0.86
BXD62/RwwJ m 25.5 27.577   2   19.5 1.0815 6.0, 45.0 -0.11
BXD63/RwwJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -1.89
BXD65/RwwJ f 49.333 15.275   3 8.8192 0.3096 36.0, 66.0 1.46
BXD65/RwwJ m 29.667 21.032   3 12.143 0.7089 8.0, 50.0 0.21
BXD68/RwwJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -1.27
BXD68/RwwJ m 37.5 4.9497   2   3.5 0.132 34.0, 41.0 0.81
BXD69/RwwJ f 33.5 0.70711   2   0.5 0.0211 33.0, 34.0 0.53
BXD70/RwwJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.21
BXD70/RwwJ m 57.0 0.0   1   0.0 0.0 57.0, 57.0 2.29
BXD71/RwwJ f 30.0 0.0   1   0.0 0.0 30.0, 30.0 0.32
BXD71/RwwJ m 20.0 15.556   2   11.0 0.7778 9.0, 31.0 -0.52
BXD73a/RwwJ f 31.5 10.607   2   7.5 0.3367 24.0, 39.0 0.41
BXD73a/RwwJ m 32.0 0.0   1   0.0 0.0 32.0, 32.0 0.39
BXD75/RwwJ f 45.0 0.0   1   0.0 0.0 45.0, 45.0 1.21
BXD75/RwwJ m 30.0 11.314   2   8.0 0.3771 22.0, 38.0 0.24
BXD77/RwwJ f 40.0 0.0   1   0.0 0.0 40.0, 40.0 0.91
BXD77/RwwJ m 20.333 30.892   3 17.836 1.5193 2.0, 56.0 -0.5
BXD84/RwwJ f 10.667 11.719   3 6.7659 1.0986 2.0, 24.0 -0.82
BXD84/RwwJ m 23.0 6.5574   3 3.7859 0.2851 17.0, 30.0 -0.3
BXD90/RwwJ m 43.5 20.506   2   14.5 0.4714 29.0, 58.0 1.26
BXD98/RwwJ f 42.0 12.728   2   9.0 0.303 33.0, 51.0 1.03
BXD98/RwwJ m 32.333 9.4516   3 5.4569 0.2923 25.0, 43.0 0.41
BXD99/RwwJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.44
BXD99/RwwJ m 42.0 0.0   1   0.0 0.0 42.0, 42.0 1.15
C3HeB/FeJ f 8.0 12.124   3 7.0 1.5155 1.0, 22.0 -0.97
C3HeB/FeJ m 27.0 7.0711   2   5.0 0.2619 22.0, 32.0 0.01
C3H/HeJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -1.33
C3H/HeJ m 7.6667 11.547   3 6.6667 1.5061 1.0, 21.0 -1.46
C57BL/10J f 40.0 28.478   3 16.442 0.712 9.0, 65.0 0.91
C57BL/10J m 26.333 9.0185   3 5.2068 0.3425 17.0, 35.0 -0.04
C57BL/6J f 12.0 19.053   3 11.0 1.5877 1.0, 34.0 -0.74
C57BL/6J m 36.0 4.0   3 2.3094 0.1111 32.0, 40.0 0.69
C57BLKS/J f 31.5 3.5355   2   2.5 0.1122 29.0, 34.0 0.41
C57BLKS/J m 11.5 12.021   2   8.5 1.0453 3.0, 20.0 -1.17
C57BR/cdJ f 45.0 17.059   3 9.8489 0.3791 31.0, 64.0 1.21
C57BR/cdJ m 31.333 2.3094   3 1.3333 0.0737 30.0, 34.0 0.34
C57L/J f 55.0 0.0   1   0.0 0.0 55.0, 55.0 1.8
C57L/J m 37.333 6.0277   3 3.4801 0.1615 31.0, 43.0 0.79
C58/J f 43.0 15.1   3 8.7178 0.3512 27.0, 57.0 1.09
C58/J m 31.667 12.014   3 6.9362 0.3794 20.0, 44.0 0.36
CBA/J f 13.333 18.824   3 10.868 1.4118 1.0, 35.0 -0.66
CBA/J m 14.0 13.0   3 7.5056 0.9286 6.0, 29.0 -0.98
DBA/1J f 8.0 5.0   3 2.8868 0.625 3.0, 13.0 -0.97
DBA/1J m 13.0 0.0   1   0.0 0.0 13.0, 13.0 -1.06
DBA/2J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.39
FVB/NJ f 6.0 7.0711   2   5.0 1.1785 1.0, 11.0 -1.09
FVB/NJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -1.66
I/LnJ f 29.0 15.556   2   11.0 0.5364 18.0, 40.0 0.27
I/LnJ m 31.0 0.0   1   0.0 0.0 31.0, 31.0 0.31
KK/HlJ f 16.0 13.454   3 7.7675 0.8409 1.0, 27.0 -0.5
KK/HlJ m 32.333 6.0277   3 3.4801 0.1864 26.0, 38.0 0.41
LP/J f 3.0 0.0   2   0.0 0.0 3.0, 3.0 -1.27
LP/J m 20.5 20.506   2   14.5 1.0003 6.0, 35.0 -0.49
MA/MyJ f 41.0 6.0828   3 3.5119 0.1484 34.0, 45.0 0.97
MA/MyJ m 38.0 6.5574   3 3.7859 0.1726 31.0, 44.0 0.84
MRL/MpJ f 23.333 24.786   3 14.31 1.0622 1.0, 50.0 -0.07
MRL/MpJ m 12.667 18.475   3 10.667 1.4586 2.0, 34.0 -1.08
NOD/ShiLtJ f 44.333 24.007   3 13.86 0.5415 18.0, 65.0 1.17
NOD/ShiLtJ m 36.333 17.616   3 10.171 0.4849 16.0, 47.0 0.72
NZB/BlNJ f 4.5 4.9497   2   3.5 1.0999 1.0, 8.0 -1.18
NZB/BlNJ m 22.0 24.042   2   17.0 1.0928 5.0, 39.0 -0.37
NZO/HlLtJ f 30.333 14.048   3 8.1104 0.4631 17.0, 45.0 0.34
NZO/HlLtJ m 33.667 8.3267   3 4.8074 0.2473 27.0, 43.0 0.51
NZW/LacJ f 17.667 20.429   3 11.795 1.1563 3.0, 41.0 -0.4
NZW/LacJ m 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.68
PL/J f 16.5 20.506   2   14.5 1.2428 2.0, 31.0 -0.47
PL/J m 33.667 32.021   3 18.487 0.9511 1.0, 65.0 0.51
SJL/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.39
SJL/J m 1.0 0.0   2   0.0 0.0 1.0, 1.0 -1.97
SM/J f 30.25 6.6018   4 3.3009 0.2182 23.0, 39.0 0.34
SM/J m 23.25 11.295   4 5.6476 0.4858 10.0, 37.0 -0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 20.3333333333 9.0689836612 38.3059302973 2.3607363694
A/J m 1.6666666667 9.0689836612 19.6392636306 -16.3059302973
AKR/J f 5.0 9.0689836612 22.9725969639 -12.9725969639
AKR/J m 21.0 11.1071912277 43.0118459572 -1.0118459572
BALB/cByJ f 30.0 9.0689836612 47.9725969639 12.0274030361
BALB/cByJ m 22.6666666667 9.0689836612 40.6392636306 4.6940697027
BALB/cJ f 24.3333333333 9.0689836612 42.3059302973 6.3607363694
BALB/cJ m 26.6666666667 9.0689836612 44.6392636306 8.6940697027
BPL/1J f 44.3333333333 9.0689836612 62.3059302973 26.3607363694
BPL/1J m 15.0 9.0689836612 32.9725969639 -2.9725969639
BXD2/TyJ f 21.6666666667 9.0689836612 39.6392636306 3.6940697027
BXD2/TyJ m 51.3333333333 9.0689836612 69.3059302973 33.3607363694
BXD31/TyJ f 39.0 9.0689836612 56.9725969639 21.0274030361
BXD31/TyJ m 23.5 7.8539702371 39.0647255427 7.9352744573
BXD38/TyJ f 35.0 9.0689836612 52.9725969639 17.0274030361
BXD38/TyJ m 45.0 9.0689836612 62.9725969639 27.0274030361
BXD42/TyJ f 40.5 11.1071912277 62.5118459572 18.4881540428
BXD42/TyJ m 46.6666666667 9.0689836612 64.6392636306 28.6940697027
BXD48a/RwwJ f 25.0 9.0689836612 42.9725969639 7.0274030361
BXD48a/RwwJ m 30.6666666667 9.0689836612 48.6392636306 12.6940697027
BXD62/RwwJ f 10.0 11.1071912277 32.0118459572 -12.0118459572
BXD62/RwwJ m 25.5 11.1071912277 47.5118459572 3.4881540428
BXD65/RwwJ f 49.3333333333 9.0689836612 67.3059302973 31.3607363694
BXD65/RwwJ m 29.6666666667 9.0689836612 47.6392636306 11.6940697027
BXD84/RwwJ f 10.6666666667 9.0689836612 28.6392636306 -7.3059302973
BXD84/RwwJ m 23.0 9.0689836612 40.9725969639 5.0274030361
BXD98/RwwJ f 42.0 11.1071912277 64.0118459572 19.9881540428
BXD98/RwwJ m 32.3333333333 9.0689836612 50.3059302973 14.3607363694
C3HeB/FeJ f 8.0 9.0689836612 25.9725969639 -9.9725969639
C3HeB/FeJ m 27.0 11.1071912277 49.0118459572 4.9881540428
C57BL/10J f 40.0 9.0689836612 57.9725969639 22.0274030361
C57BL/10J m 26.3333333333 9.0689836612 44.3059302973 8.3607363694
C57BL/6J f 12.0 9.0689836612 29.9725969639 -5.9725969639
C57BL/6J m 36.0 9.0689836612 53.9725969639 18.0274030361
C57BLKS/J f 31.5 11.1071912277 53.5118459572 9.4881540428
C57BLKS/J m 11.5 11.1071912277 33.5118459572 -10.5118459572
C57BR/cdJ f 45.0 9.0689836612 62.9725969639 27.0274030361
C57BR/cdJ m 31.3333333333 9.0689836612 49.3059302973 13.3607363694
C58/J f 43.0 9.0689836612 60.9725969639 25.0274030361
C58/J m 31.6666666667 9.0689836612 49.6392636306 13.6940697027
CBA/J f 13.3333333333 9.0689836612 31.3059302973 -4.6392636306
CBA/J m 14.0 9.0689836612 31.9725969639 -3.9725969639
KK/HlJ f 16.0 9.0689836612 33.9725969639 -1.9725969639
KK/HlJ m 32.3333333333 9.0689836612 50.3059302973 14.3607363694
LP/J f 3.0 11.1071912277 25.0118459572 -19.0118459572
LP/J m 20.5 11.1071912277 42.5118459572 -1.5118459572
MA/MyJ f 41.0 9.0689836612 58.9725969639 23.0274030361
MA/MyJ m 38.0 9.0689836612 55.9725969639 20.0274030361
MRL/MpJ f 23.3333333333 9.0689836612 41.3059302973 5.3607363694
MRL/MpJ m 12.6666666667 9.0689836612 30.6392636306 -5.3059302973
NOD/ShiLtJ f 44.3333333333 9.0689836612 62.3059302973 26.3607363694
NOD/ShiLtJ m 36.3333333333 9.0689836612 54.3059302973 18.3607363694
NZB/BlNJ f 4.5 11.1071912277 26.5118459572 -17.5118459572
NZB/BlNJ m 22.0 11.1071912277 44.0118459572 -0.0118459572
NZO/HlLtJ f 30.3333333333 9.0689836612 48.3059302973 12.3607363694
NZO/HlLtJ m 33.6666666667 9.0689836612 51.6392636306 15.6940697027
PL/J f 16.5 11.1071912277 38.5118459572 -5.5118459572
PL/J m 33.6666666667 9.0689836612 51.6392636306 15.6940697027
SM/J f 30.25 7.8539702371 45.8147255427 14.6852744573
SM/J m 23.25 7.8539702371 38.8147255427 7.6852744573


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 11.0 6.4127398453 23.7085451887 -1.7085451887
AKR/J both 13.0 7.169661108 27.2085854686 -1.2085854686
BALB/cByJ both 26.3333333333 6.4127398453 39.0418785221 13.6247881446
BALB/cJ both 25.5 6.4127398453 38.2085451887 12.7914548113
BPL/1J both 29.6666666667 6.4127398453 42.3752118554 16.9581214779
BXD2/TyJ both 36.5 6.4127398453 49.2085451887 23.7914548113
BXD31/TyJ both 31.25 5.9985688529 43.1377554951 19.3622445049
BXD38/TyJ both 40.0 6.4127398453 52.7085451887 27.2914548113
BXD42/TyJ both 43.5833333333 7.169661108 57.7919188019 29.3747478648
BXD48a/RwwJ both 27.8333333333 6.4127398453 40.5418785221 15.1247881446
BXD62/RwwJ both 17.75 7.8539702371 33.3147255427 2.1852744573
BXD65/RwwJ both 39.5 6.4127398453 52.2085451887 26.7914548113
BXD84/RwwJ both 16.8333333333 6.4127398453 29.5418785221 4.1247881446
BXD98/RwwJ both 37.1666666667 7.169661108 51.3752521352 22.9580811981
C3HeB/FeJ both 17.5 7.169661108 31.7085854686 3.2914145314
C57BL/10J both 33.1666666667 6.4127398453 45.8752118554 20.4581214779
C57BL/6J both 24.0 6.4127398453 36.7085451887 11.2914548113
C57BLKS/J both 21.5 7.8539702371 37.0647255427 5.9352744573
C57BR/cdJ both 38.1666666667 6.4127398453 50.8752118554 25.4581214779
C58/J both 37.3333333333 6.4127398453 50.0418785221 24.6247881446
CBA/J both 13.6666666667 6.4127398453 26.3752118554 0.9581214779
KK/HlJ both 24.1666666667 6.4127398453 36.8752118554 11.4581214779
LP/J both 11.75 7.8539702371 27.3147255427 -3.8147255427
MA/MyJ both 39.5 6.4127398453 52.2085451887 26.7914548113
MRL/MpJ both 18.0 6.4127398453 30.7085451887 5.2914548113
NOD/ShiLtJ both 40.3333333333 6.4127398453 53.0418785221 27.6247881446
NZB/BlNJ both 13.25 7.8539702371 28.8147255427 -2.3147255427
NZO/HlLtJ both 32.0 6.4127398453 44.7085451887 19.2914548113
PL/J both 25.0833333333 7.169661108 39.2919188019 10.8747478648
SM/J both 26.75 5.5535956139 37.7559229786 15.7440770214




  GWAS USING LINEAR MIXED MODELS