Project measure / variable:   Project1032   inactive_d10_cocaine

ID, description, units MPD:111511   inactive_d10_cocaine   number of inactive lever presses (intravenous self administration), cocaine   [n]  day 10  
cocaine study
Data set, strains Project1032   HMDP   66 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of inactive lever presses (intravenous self administration), cocaine day 10



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested60 strains57 strains
Mean of the strain means12.417   n 26.72   n
Median of the strain means4.1667   n 8.0   n
SD of the strain means± 22.031 ± 53.67
Coefficient of variation (CV)1.7743 2.0087
Min–max range of strain means1.0   –   119.0   n 1.0   –   296.7   n
Mean sample size per strain1.9   mice 1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 10078.6231 10078.6231 1.142 0.2895
strain 19 182026.8098 9580.3584 1.0856 0.3878
sex:strain 19 122090.727 6425.8277 0.7281 0.7757
Residuals 60 529508.0 8825.1333


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.44
129X1/SvJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
A/J f 17.667 23.692   3 13.679 1.3411 3.0, 45.0 0.24
A/J m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.4
AKR/J m 1.6667 1.1547   3 0.66667 0.6928 1.0, 3.0 -0.47
BALB/cByJ f 4.0 2.6458   3 1.5275 0.6614 2.0, 7.0 -0.38
BALB/cByJ m 7.0 2.8284   2   2.0 0.4041 5.0, 9.0 -0.37
BALB/cJ f 7.0 9.5394   3 5.5076 1.3628 1.0, 18.0 -0.25
BALB/cJ m 14.667 10.97   3 6.3333 0.7479 6.0, 27.0 -0.22
BPL/1J f 52.33 59.65   3 34.44 1.1398 4.0, 119.0 1.81
BPL/1J m 15.667 11.93   3 6.888 0.7615 2.0, 24.0 -0.21
BTBR T+ Itpr3tf/J f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.52
BTBR T+ Itpr3tf/J m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.46
BXD100/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.47
BXD100/RwwJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.46
BXD11/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
BXD11/TyJ m 234.0 0.0   1   0.0 0.0 234.0, 234.0 3.86
BXD15/TyJ f 4.3333 4.9329   3 2.848 1.1384 1.0, 10.0 -0.37
BXD1/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
BXD1/TyJ m 3.0 0.0   2   0.0 0.0 3.0, 3.0 -0.44
BXD21/TyJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.43
BXD21/TyJ m 15.0 11.314   2   8.0 0.7542 7.0, 23.0 -0.22
BXD28/TyJ f 26.0 0.0   1   0.0 0.0 26.0, 26.0 0.62
BXD2/TyJ f 51.0 52.37   3 30.238 1.0269 10.0, 110.0 1.75
BXD2/TyJ m 23.0 28.284   2   20.0 1.2298 3.0, 43.0 -0.07
BXD31/TyJ f 5.0 4.2426   2   3.0 0.8485 2.0, 8.0 -0.34
BXD31/TyJ m 16.333 15.948   3 9.2075 0.9764 3.0, 34.0 -0.19
BXD32/TyJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.34
BXD32/TyJ m 17.5 20.506   2   14.5 1.1718 3.0, 32.0 -0.17
BXD34/TyJ f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.5
BXD34/TyJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.46
BXD38/TyJ f 5.6667 2.5166   3 1.453 0.4441 3.0, 8.0 -0.31
BXD38/TyJ m 144.0 199.4   2   141.0 1.3848 3.0, 285.0 2.19
BXD39/TyJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.2
BXD39/TyJ m 6.0 0.0   2   0.0 0.0 6.0, 6.0 -0.39
BXD40/TyJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.52
BXD42/TyJ f 15.0 0.0   1   0.0 0.0 15.0, 15.0 0.12
BXD42/TyJ m 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.14
BXD48a/RwwJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.52
BXD48a/RwwJ m 12.667 11.06   3 6.3857 0.8732 1.0, 23.0 -0.26
BXD50/RwwJ f 49.0 0.0   1   0.0 0.0 49.0, 49.0 1.66
BXD50/RwwJ m 8.5 2.1213   2   1.5 0.2496 7.0, 10.0 -0.34
BXD55/RwwJ f 3.5 3.5355   2   2.5 1.0102 1.0, 6.0 -0.4
BXD55/RwwJ m 80.0 0.0   1   0.0 0.0 80.0, 80.0 0.99
BXD56/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
BXD60/RwwJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.38
BXD60/RwwJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.4
BXD61/RwwJ f 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.4
BXD62/RwwJ f 7.3333 5.5076   3 3.1798 0.751 2.0, 13.0 -0.23
BXD62/RwwJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.35
BXD63/RwwJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.22
BXD65/RwwJ f 9.0 1.4142   2   1.0 0.1571 8.0, 10.0 -0.16
BXD65/RwwJ m 8.0 7.0711   2   5.0 0.8839 3.0, 13.0 -0.35
BXD68/RwwJ m 4.0 2.8284   2   2.0 0.7071 2.0, 6.0 -0.42
BXD69/RwwJ f 49.0 65.05   2   46.0 1.3276 3.0, 95.0 1.66
BXD70/RwwJ f 15.0 0.0   1   0.0 0.0 15.0, 15.0 0.12
BXD70/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.48
BXD71/RwwJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.38
BXD71/RwwJ m 14.0 15.556   2   11.0 1.1112 3.0, 25.0 -0.24
BXD73a/RwwJ f 6.0 7.0711   2   5.0 1.1785 1.0, 11.0 -0.29
BXD73a/RwwJ m 91.0 0.0   1   0.0 0.0 91.0, 91.0 1.2
BXD75/RwwJ f 19.0 0.0   1   0.0 0.0 19.0, 19.0 0.3
BXD75/RwwJ m 6.5 0.70711   2   0.5 0.1088 6.0, 7.0 -0.38
BXD77/RwwJ f 3.0 2.8284   2   2.0 0.9428 1.0, 5.0 -0.43
BXD77/RwwJ m 4.0 4.2426   2   3.0 1.0607 1.0, 7.0 -0.42
BXD84/RwwJ f 2.6667 2.8868   3 1.6667 1.0825 1.0, 6.0 -0.44
BXD84/RwwJ m 12.667 17.673   3 10.203 1.3952 1.0, 33.0 -0.26
BXD90/RwwJ m 12.0 12.728   2   9.0 1.0607 3.0, 21.0 -0.27
BXD98/RwwJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.29
BXD98/RwwJ m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.47
BXD99/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.47
BXD99/RwwJ m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.42
C3HeB/FeJ f 5.3333 4.9329   3 2.848 0.9249 2.0, 11.0 -0.32
C3HeB/FeJ m 4.0 1.4142   2   1.0 0.3536 3.0, 5.0 -0.42
C3H/HeJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
C3H/HeJ m 30.5 38.891   2   27.5 1.2751 3.0, 58.0 0.07
C57BL/10J f 5.5 0.70711   2   0.5 0.1286 5.0, 6.0 -0.31
C57BL/10J m 2.6667 1.5275   3 0.88192 0.5728 1.0, 4.0 -0.45
C57BL/6J f 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.16
C57BL/6J m 8.6667 9.815   3 5.6667 1.1325 3.0, 20.0 -0.34
C57BLKS/J f 53.33 77.73   3 44.879 1.4575 5.0, 143.0 1.86
C57BLKS/J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.48
C57BR/cdJ f 12.5 16.263   2   11.5 1.3011 1.0, 24.0 0.0
C57BR/cdJ m 4.0 0.0   2   0.0 0.0 4.0, 4.0 -0.42
C57L/J f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.47
C57L/J m 38.0 46.228   3 26.69 1.2165 6.0, 91.0 0.21
C58/J f 2.6667 2.0817   3 1.2019 0.7806 1.0, 5.0 -0.44
C58/J m 7.5 7.7782   2   5.5 1.0371 2.0, 13.0 -0.36
CBA/J f 2.6667 0.57735   3 0.33333 0.2165 2.0, 3.0 -0.44
CBA/J m 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.45
DBA/1J f 1.0 0.0   3 0.0 0.0 1.0, 1.0 -0.52
DBA/1J m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.46
DBA/2J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
FVB/NJ f 15.5 20.506   2   14.5 1.323 1.0, 30.0 0.14
FVB/NJ m 10.5 12.021   2   8.5 1.1448 2.0, 19.0 -0.3
I/LnJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.43
I/LnJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.35
KK/HlJ f 4.5 3.5355   2   2.5 0.7857 2.0, 7.0 -0.36
KK/HlJ m 296.7 465.5   3 268.8 1.5691 16.0, 834.0 5.03
LP/J m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.44
MA/MyJ f 87.5 98.29   2   69.5 1.1233 18.0, 157.0 3.41
MA/MyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.48
MRL/MpJ f 4.3333 4.9329   3 2.848 1.1384 1.0, 10.0 -0.37
MRL/MpJ m 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.43
NOD/ShiLtJ f 119.0 126.6   3 73.11 1.0641 25.0, 263.0 4.84
NOD/ShiLtJ m 87.0 60.81   2   43.0 0.699 44.0, 130.0 1.12
NZB/BlNJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.47
NZB/BlNJ m 8.5 9.1924   2   6.5 1.0815 2.0, 15.0 -0.34
NZO/HlLtJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
NZO/HlLtJ m 29.667 47.931   3 27.673 1.6156 1.0, 85.0 0.05
NZW/LacJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
NZW/LacJ m 54.0 0.0   1   0.0 0.0 54.0, 54.0 0.51
PL/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.52
PL/J m 72.67 48.521   3 28.014 0.6677 25.0, 122.0 0.86
SJL/J f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.52
SM/J f 11.667 9.2916   3 5.3645 0.7964 4.0, 22.0 -0.03
SM/J m 29.0 43.405   3 25.06 1.4967 1.0, 79.0 0.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ f 4.0 54.2375433728 112.4912398799 -104.4912398799
BALB/cByJ m 7.0 66.4271530827 139.8740896338 -125.8740896338
BALB/cJ f 7.0 54.2375433728 115.4912398799 -101.4912398799
BALB/cJ m 14.6666666667 54.2375433728 123.1579065466 -93.8245732133
BPL/1J f 52.3333333333 54.2375433728 160.8245732133 -56.1579065466
BPL/1J m 15.6666666667 54.2375433728 124.1579065466 -92.8245732133
BXD2/TyJ f 51.0 54.2375433728 159.4912398799 -57.4912398799
BXD2/TyJ m 23.0 66.4271530827 155.8740896338 -109.8740896338
BXD31/TyJ f 5.0 66.4271530827 137.8740896338 -127.8740896338
BXD31/TyJ m 16.3333333333 54.2375433728 124.8245732133 -92.1579065466
BXD38/TyJ f 5.6666666667 54.2375433728 114.1579065466 -102.8245732133
BXD38/TyJ m 144.0 66.4271530827 276.8740896338 11.1259103662
BXD48a/RwwJ f 1.0 66.4271530827 133.8740896338 -131.8740896338
BXD48a/RwwJ m 12.6666666667 54.2375433728 121.1579065466 -95.8245732133
BXD65/RwwJ f 9.0 66.4271530827 141.8740896338 -123.8740896338
BXD65/RwwJ m 8.0 66.4271530827 140.8740896338 -124.8740896338
BXD77/RwwJ f 3.0 66.4271530827 135.8740896338 -129.8740896338
BXD77/RwwJ m 4.0 66.4271530827 136.8740896338 -128.8740896338
BXD84/RwwJ f 2.6666666667 54.2375433728 111.1579065466 -105.8245732133
BXD84/RwwJ m 12.6666666667 54.2375433728 121.1579065466 -95.8245732133
C3HeB/FeJ f 5.3333333333 54.2375433728 113.8245732133 -103.1579065466
C3HeB/FeJ m 4.0 66.4271530827 136.8740896338 -128.8740896338
C57BL/10J f 5.5 66.4271530827 138.3740896338 -127.3740896338
C57BL/10J m 2.6666666667 54.2375433728 111.1579065466 -105.8245732133
C57BR/cdJ f 12.5 66.4271530827 145.3740896338 -120.3740896338
C57BR/cdJ m 4.0 66.4271530827 136.8740896338 -128.8740896338
C58/J f 2.6666666667 54.2375433728 111.1579065466 -105.8245732133
C58/J m 7.5 66.4271530827 140.3740896338 -125.3740896338
CBA/J f 2.6666666667 54.2375433728 111.1579065466 -105.8245732133
CBA/J m 2.5 66.4271530827 135.3740896338 -130.3740896338
FVB/NJ f 15.5 66.4271530827 148.3740896338 -117.3740896338
FVB/NJ m 10.5 66.4271530827 143.3740896338 -122.3740896338
KK/HlJ f 4.5 66.4271530827 137.3740896338 -128.3740896338
KK/HlJ m 296.6666666667 54.2375433728 405.1579065466 188.1754267867
MRL/MpJ f 4.3333333333 54.2375433728 112.8245732133 -104.1579065466
MRL/MpJ m 3.5 66.4271530827 136.3740896338 -129.3740896338
NOD/ShiLtJ f 119.0 54.2375433728 227.4912398799 10.5087601201
NOD/ShiLtJ m 87.0 66.4271530827 219.8740896338 -45.8740896338
SM/J f 11.6666666667 54.2375433728 120.1579065466 -96.8245732133
SM/J m 29.0 54.2375433728 137.4912398799 -79.4912398799


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ both 5.5 42.8785429375 91.2698560491 -80.2698560491
BALB/cJ both 10.8333333333 38.3517347138 87.5482247518 -65.8815580851
BPL/1J both 34.0 38.3517347138 110.7148914184 -42.7148914184
BXD2/TyJ both 37.0 42.8785429375 122.7698560491 -48.7698560491
BXD31/TyJ both 10.6666666667 42.8785429375 96.4365227157 -75.1031893824
BXD38/TyJ both 74.8333333333 42.8785429375 160.6031893824 -10.9365227157
BXD48a/RwwJ both 6.8333333333 42.8785429375 92.6031893824 -78.9365227157
BXD65/RwwJ both 8.5 46.9710903997 102.4561698241 -85.4561698241
BXD77/RwwJ both 3.5 46.9710903997 97.4561698241 -90.4561698241
BXD84/RwwJ both 7.6666666667 38.3517347138 84.3815580851 -69.0482247518
C3HeB/FeJ both 4.6666666667 42.8785429375 90.4365227157 -81.1031893824
C57BL/10J both 4.0833333333 42.8785429375 89.8531893824 -81.6865227157
C57BR/cdJ both 8.25 46.9710903997 102.2061698241 -85.7061698241
C58/J both 5.0833333333 42.8785429375 90.8531893824 -80.6865227157
CBA/J both 2.5833333333 42.8785429375 88.3531893824 -83.1865227157
FVB/NJ both 13.0 46.9710903997 106.9561698241 -80.9561698241
KK/HlJ both 150.5833333333 42.8785429375 236.3531893824 64.8134772843
MRL/MpJ both 3.9166666667 42.8785429375 89.6865227157 -81.8531893824
NOD/ShiLtJ both 103.0 42.8785429375 188.7698560491 17.2301439509
SM/J both 20.3333333333 38.3517347138 97.0482247518 -56.3815580851




  GWAS USING LINEAR MIXED MODELS