Project measure / variable:   Project1032   infusions_d4_cocaine

ID, description, units MPD:111427   infusions_d4_cocaine   number of infusions earned (intravenous self administration), cocaine   [n]  day 4  
cocaine study
Data set, strains Project1032   HMDP   64 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of infusions earned (intravenous self administration), cocaine day 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested58 strains61 strains
Mean of the strain means23.675   n 22.424   n
Median of the strain means22.0   n 22.0   n
SD of the strain means± 17.506 ± 13.759
Coefficient of variation (CV)0.7394 0.6136
Min–max range of strain means1.0   –   65.0   n 1.0   –   57.5   n
Mean sample size per strain2.1   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12.2427 12.2427 0.0597 0.8074
strain 34 22658.0916 666.4145 3.2494 < 0.0001
sex:strain 34 12675.8528 372.8192 1.8179 0.0101
Residuals 117 23995.0 205.0855


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 57.5 10.607   2   7.5 0.1845 50.0, 65.0 2.55
129X1/SvJ f 35.0 0.0   1   0.0 0.0 35.0, 35.0 0.65
A/J f 15.333 7.6376   3 4.4096 0.4981 7.0, 22.0 -0.48
A/J m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -1.52
AKR/J f 9.0 7.0711   2   5.0 0.7857 4.0, 14.0 -0.84
AKR/J m 20.5 14.849   2   10.5 0.7244 10.0, 31.0 -0.14
BALB/cByJ f 10.667 8.5049   3 4.9103 0.7973 1.0, 17.0 -0.74
BALB/cByJ m 24.0 13.0   3 7.5056 0.5417 16.0, 39.0 0.11
BALB/cJ f 32.0 12.728   2   9.0 0.3977 23.0, 41.0 0.48
BALB/cJ m 7.0 7.2111   3 4.1633 1.0302 1.0, 15.0 -1.12
BPL/1J f 48.0 18.682   3 10.786 0.3892 28.0, 65.0 1.39
BPL/1J m 19.0 5.2915   3 3.0551 0.2785 15.0, 25.0 -0.25
BTBR T+ Itpr3tf/J f 8.0 9.8995   2   7.0 1.2374 1.0, 15.0 -0.9
BTBR T+ Itpr3tf/J m 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -1.45
BXD100/RwwJ f 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -1.15
BXD100/RwwJ m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.61
BXD11/TyJ f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -1.27
BXD11/TyJ m 14.5 19.092   2   13.5 1.3167 1.0, 28.0 -0.58
BXD15/TyJ f 55.0 4.3589   3 2.5166 0.0793 52.0, 60.0 1.79
BXD15/TyJ m 24.0 0.0   1   0.0 0.0 24.0, 24.0 0.11
BXD1/TyJ f 28.0 38.184   2   27.0 1.3637 1.0, 55.0 0.25
BXD1/TyJ m 45.667 16.773   3 9.6839 0.3673 35.0, 65.0 1.69
BXD21/TyJ f 65.0 0.0   1   0.0 0.0 65.0, 65.0 2.36
BXD21/TyJ m 40.5 34.648   2   24.5 0.8555 16.0, 65.0 1.31
BXD2/TyJ f 20.667 10.066   3 5.8119 0.4871 10.0, 30.0 -0.17
BXD2/TyJ m 50.67 15.011   3 8.6667 0.2963 36.0, 66.0 2.05
BXD31/TyJ f 32.667 12.741   3 7.356 0.39 18.0, 41.0 0.51
BXD31/TyJ m 15.25 14.221   4 7.1107 0.9326 6.0, 36.0 -0.52
BXD32/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.3
BXD32/TyJ m 23.333 21.548   3 12.441 0.9235 1.0, 44.0 0.07
BXD34/TyJ f 16.0 4.2426   2   3.0 0.2652 13.0, 19.0 -0.44
BXD38/TyJ f 37.0 19.799   2   14.0 0.5351 23.0, 51.0 0.76
BXD38/TyJ m 35.333 5.0332   3 2.9059 0.1424 30.0, 40.0 0.94
BXD39/TyJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -1.24
BXD39/TyJ m 8.3333 10.214   3 5.8973 1.2257 1.0, 20.0 -1.02
BXD40/TyJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -1.24
BXD40/TyJ m 17.5 23.335   2   16.5 1.3334 1.0, 34.0 -0.36
BXD42/TyJ f 10.5 7.7782   2   5.5 0.7408 5.0, 16.0 -0.75
BXD42/TyJ m 36.667 3.2146   3 1.8559 0.0877 33.0, 39.0 1.04
BXD48a/RwwJ f 23.0 18.385   2   13.0 0.7993 10.0, 36.0 -0.04
BXD48a/RwwJ m 41.667 20.429   3 11.795 0.4903 27.0, 65.0 1.4
BXD50/RwwJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -1.18
BXD50/RwwJ m 14.0 15.556   2   11.0 1.1112 3.0, 25.0 -0.61
BXD55/RwwJ f 41.0 12.728   2   9.0 0.3104 32.0, 50.0 0.99
BXD55/RwwJ m 34.0 0.0   1   0.0 0.0 34.0, 34.0 0.84
BXD60/RwwJ f 42.0 0.0   1   0.0 0.0 42.0, 42.0 1.05
BXD60/RwwJ m 16.5 19.092   2   13.5 1.1571 3.0, 30.0 -0.43
BXD61/RwwJ f 6.3333 6.6583   3 3.8442 1.0513 2.0, 14.0 -0.99
BXD61/RwwJ m 32.0 0.0   1   0.0 0.0 32.0, 32.0 0.7
BXD62/RwwJ f 4.6667 0.57735   3 0.33333 0.1237 4.0, 5.0 -1.09
BXD62/RwwJ m 23.0 24.042   2   17.0 1.0453 6.0, 40.0 0.04
BXD63/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.56
BXD65/RwwJ f 50.33 10.017   3 5.7831 0.199 40.0, 60.0 1.52
BXD65/RwwJ m 20.0 18.248   3 10.536 0.9124 8.0, 41.0 -0.18
BXD68/RwwJ m 29.0 4.2426   2   3.0 0.1463 26.0, 32.0 0.48
BXD69/RwwJ f 38.5 3.5355   2   2.5 0.0918 36.0, 41.0 0.85
BXD70/RwwJ m 27.0 0.0   1   0.0 0.0 27.0, 27.0 0.33
BXD71/RwwJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 1.1
BXD71/RwwJ m 21.5 26.163   2   18.5 1.2169 3.0, 40.0 -0.07
BXD73a/RwwJ f 33.5 6.364   2   4.5 0.19 29.0, 38.0 0.56
BXD73a/RwwJ m 33.0 0.0   1   0.0 0.0 33.0, 33.0 0.77
BXD75/RwwJ f 44.0 0.0   1   0.0 0.0 44.0, 44.0 1.16
BXD75/RwwJ m 33.5 12.021   2   8.5 0.3588 25.0, 42.0 0.81
BXD77/RwwJ f 25.0 32.527   2   23.0 1.3011 2.0, 48.0 0.08
BXD77/RwwJ m 29.667 17.388   3 10.039 0.5861 10.0, 43.0 0.53
BXD84/RwwJ f 29.333 25.502   3 14.723 0.8694 4.0, 55.0 0.32
BXD84/RwwJ m 14.667 8.9629   3 5.1747 0.6111 9.0, 25.0 -0.56
BXD90/RwwJ m 20.5 21.92   2   15.5 1.0693 5.0, 36.0 -0.14
BXD98/RwwJ f 34.5 21.92   2   15.5 0.6354 19.0, 50.0 0.62
BXD98/RwwJ m 39.667 22.745   3 13.132 0.5734 21.0, 65.0 1.25
BXD99/RwwJ m 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.25
C3HeB/FeJ f 6.0 7.0711   2   5.0 1.1785 1.0, 11.0 -1.01
C3HeB/FeJ m 43.0 31.113   2   22.0 0.7236 21.0, 65.0 1.5
C3H/HeJ f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -1.27
C3H/HeJ m 2.6667 2.8868   3 1.6667 1.0825 1.0, 6.0 -1.44
C57BL/10J f 25.0 15.62   3 9.0185 0.6248 7.0, 35.0 0.08
C57BL/10J m 23.333 7.7675   3 4.4845 0.3329 17.0, 32.0 0.07
C57BL/6J f 18.0 24.042   2   17.0 1.3356 1.0, 35.0 -0.32
C57BL/6J m 23.25 15.714   4 7.8568 0.6759 1.0, 38.0 0.06
C57BLKS/J f 34.0 2.8284   2   2.0 0.0832 32.0, 36.0 0.59
C57BLKS/J m 10.333 15.308   3 8.838 1.4814 1.0, 28.0 -0.88
C57BR/cdJ f 40.0 6.0828   3 3.5119 0.1521 33.0, 44.0 0.93
C57BR/cdJ m 29.333 1.1547   3 0.66667 0.0394 28.0, 30.0 0.5
C57L/J f 54.0 0.0   1   0.0 0.0 54.0, 54.0 1.73
C57L/J m 38.667 4.5092   3 2.6034 0.1166 34.0, 43.0 1.18
C58/J f 45.333 14.048   3 8.1104 0.3099 32.0, 60.0 1.24
C58/J m 32.333 8.1445   3 4.7022 0.2519 23.0, 38.0 0.72
CBA/J f 3.0 3.4641   3 2.0 1.1547 1.0, 7.0 -1.18
CBA/J m 11.0 10.583   3 6.1101 0.9621 3.0, 23.0 -0.83
DBA/1J f 10.5 10.607   2   7.5 1.0102 3.0, 18.0 -0.75
DBA/1J m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.34
DBA/2J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.3
DBA/2J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.56
FVB/NJ f 4.6667 5.5076   3 3.1798 1.1802 1.0, 11.0 -1.09
FVB/NJ m 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -1.38
I/LnJ f 18.5 10.607   2   7.5 0.5733 11.0, 26.0 -0.3
I/LnJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -1.27
KK/HlJ f 11.0 0.0   1   0.0 0.0 11.0, 11.0 -0.72
KK/HlJ m 37.0 14.422   3 8.3267 0.3898 21.0, 49.0 1.06
LP/J f 28.0 35.355   2   25.0 1.2627 3.0, 53.0 0.25
LP/J m 23.0 1.4142   2   1.0 0.0615 22.0, 24.0 0.04
MA/MyJ f 38.0 13.0   3 7.5056 0.3421 25.0, 51.0 0.82
MA/MyJ m 35.333 4.9329   3 2.848 0.1396 32.0, 41.0 0.94
MRL/MpJ f 21.0 28.284   2   20.0 1.3469 1.0, 41.0 -0.15
MRL/MpJ m 14.333 19.655   3 11.348 1.3713 2.0, 37.0 -0.59
NOD/ShiLtJ f 41.667 2.8868   3 1.6667 0.0693 40.0, 45.0 1.03
NOD/ShiLtJ m 35.667 3.0551   3 1.7638 0.0857 33.0, 39.0 0.96
NZB/BlNJ f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -1.27
NZB/BlNJ m 19.667 23.245   3 13.421 1.182 2.0, 46.0 -0.2
NZO/HlLtJ f 30.0 7.2111   3 4.1633 0.2404 24.0, 38.0 0.36
NZO/HlLtJ m 6.0 6.245   3 3.6056 1.0408 1.0, 13.0 -1.19
NZW/LacJ f 19.5 26.163   2   18.5 1.3417 1.0, 38.0 -0.24
NZW/LacJ m 6.0 7.0711   2   5.0 1.1785 1.0, 11.0 -1.19
PL/J f 52.0 0.0   1   0.0 0.0 52.0, 52.0 1.62
PL/J m 33.0 30.199   3 17.436 0.9151 5.0, 65.0 0.77
SJL/J f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -1.3
SJL/J m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.56
SM/J f 17.0 12.247   4 6.1237 0.7204 7.0, 32.0 -0.38
SM/J m 22.0 8.165   4 4.0825 0.3711 12.0, 32.0 -0.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 15.3333333333 8.2681209088 31.7079135327 -1.041246866
A/J m 1.5 10.126338679 21.5546831204 -18.5546831204
AKR/J f 9.0 10.126338679 29.0546831204 -11.0546831204
AKR/J m 20.5 10.126338679 40.5546831204 0.4453168796
BALB/cByJ f 10.6666666667 8.2681209088 27.041246866 -5.7079135327
BALB/cByJ m 24.0 8.2681209088 40.3745801994 7.6254198006
BALB/cJ f 32.0 10.126338679 52.0546831204 11.9453168796
BALB/cJ m 7.0 8.2681209088 23.3745801994 -9.3745801994
BPL/1J f 48.0 8.2681209088 64.3745801994 31.6254198006
BPL/1J m 19.0 8.2681209088 35.3745801994 2.6254198006
BTBR T+ Itpr3tf/J f 8.0 10.126338679 28.0546831204 -12.0546831204
BTBR T+ Itpr3tf/J m 2.5 10.126338679 22.5546831204 -17.5546831204
BXD11/TyJ f 1.5 10.126338679 21.5546831204 -18.5546831204
BXD11/TyJ m 14.5 10.126338679 34.5546831204 -5.5546831204
BXD1/TyJ f 28.0 10.126338679 48.0546831204 7.9453168796
BXD1/TyJ m 45.6666666667 8.2681209088 62.041246866 29.2920864673
BXD2/TyJ f 20.6666666667 8.2681209088 37.041246866 4.2920864673
BXD2/TyJ m 50.6666666667 8.2681209088 67.041246866 34.2920864673
BXD31/TyJ f 32.6666666667 8.2681209088 49.041246866 16.2920864673
BXD31/TyJ m 15.25 7.1604027485 29.430802429 1.069197571
BXD38/TyJ f 37.0 10.126338679 57.0546831204 16.9453168796
BXD38/TyJ m 35.3333333333 8.2681209088 51.7079135327 18.958753134
BXD42/TyJ f 10.5 10.126338679 30.5546831204 -9.5546831204
BXD42/TyJ m 36.6666666667 8.2681209088 53.041246866 20.2920864673
BXD48a/RwwJ f 23.0 10.126338679 43.0546831204 2.9453168796
BXD48a/RwwJ m 41.6666666667 8.2681209088 58.041246866 25.2920864673
BXD62/RwwJ f 4.6666666667 8.2681209088 21.041246866 -11.7079135327
BXD62/RwwJ m 23.0 10.126338679 43.0546831204 2.9453168796
BXD65/RwwJ f 50.3333333333 8.2681209088 66.7079135327 33.958753134
BXD65/RwwJ m 20.0 8.2681209088 36.3745801994 3.6254198006
BXD77/RwwJ f 25.0 10.126338679 45.0546831204 4.9453168796
BXD77/RwwJ m 29.6666666667 8.2681209088 46.041246866 13.2920864673
BXD84/RwwJ f 29.3333333333 8.2681209088 45.7079135327 12.958753134
BXD84/RwwJ m 14.6666666667 8.2681209088 31.041246866 -1.7079135327
BXD98/RwwJ f 34.5 10.126338679 54.5546831204 14.4453168796
BXD98/RwwJ m 39.6666666667 8.2681209088 56.041246866 23.2920864673
C3HeB/FeJ f 6.0 10.126338679 26.0546831204 -14.0546831204
C3HeB/FeJ m 43.0 10.126338679 63.0546831204 22.9453168796
C3H/HeJ f 1.5 10.126338679 21.5546831204 -18.5546831204
C3H/HeJ m 2.6666666667 8.2681209088 19.041246866 -13.7079135327
C57BL/10J f 25.0 8.2681209088 41.3745801994 8.6254198006
C57BL/10J m 23.3333333333 8.2681209088 39.7079135327 6.958753134
C57BL/6J f 18.0 10.126338679 38.0546831204 -2.0546831204
C57BL/6J m 23.25 7.1604027485 37.430802429 9.069197571
C57BLKS/J f 34.0 10.126338679 54.0546831204 13.9453168796
C57BLKS/J m 10.3333333333 8.2681209088 26.7079135327 -6.041246866
C57BR/cdJ f 40.0 8.2681209088 56.3745801994 23.6254198006
C57BR/cdJ m 29.3333333333 8.2681209088 45.7079135327 12.958753134
C58/J f 45.3333333333 8.2681209088 61.7079135327 28.958753134
C58/J m 32.3333333333 8.2681209088 48.7079135327 15.958753134
CBA/J f 3.0 8.2681209088 19.3745801994 -13.3745801994
CBA/J m 11.0 8.2681209088 27.3745801994 -5.3745801994
FVB/NJ f 4.6666666667 8.2681209088 21.041246866 -11.7079135327
FVB/NJ m 3.5 10.126338679 23.5546831204 -16.5546831204
LP/J f 28.0 10.126338679 48.0546831204 7.9453168796
LP/J m 23.0 10.126338679 43.0546831204 2.9453168796
MA/MyJ f 38.0 8.2681209088 54.3745801994 21.6254198006
MA/MyJ m 35.3333333333 8.2681209088 51.7079135327 18.958753134
MRL/MpJ f 21.0 10.126338679 41.0546831204 0.9453168796
MRL/MpJ m 14.3333333333 8.2681209088 30.7079135327 -2.041246866
NOD/ShiLtJ f 41.6666666667 8.2681209088 58.041246866 25.2920864673
NOD/ShiLtJ m 35.6666666667 8.2681209088 52.041246866 19.2920864673
NZB/BlNJ f 1.5 10.126338679 21.5546831204 -18.5546831204
NZB/BlNJ m 19.6666666667 8.2681209088 36.041246866 3.2920864673
NZO/HlLtJ f 30.0 8.2681209088 46.3745801994 13.6254198006
NZO/HlLtJ m 6.0 8.2681209088 22.3745801994 -10.3745801994
NZW/LacJ f 19.5 10.126338679 39.5546831204 -0.5546831204
NZW/LacJ m 6.0 10.126338679 26.0546831204 -14.0546831204
SM/J f 17.0 7.1604027485 31.180802429 2.819197571
SM/J m 22.0 7.1604027485 36.180802429 7.819197571


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 8.4166666667 6.5365235103 21.3619089564 -4.5285756231
AKR/J both 14.75 7.1604027485 28.930802429 0.569197571
BALB/cByJ both 17.3333333333 5.8464443623 28.9119100314 5.7547566353
BALB/cJ both 19.5 6.5365235103 32.4452422898 6.5547577102
BPL/1J both 33.5 5.8464443623 45.0785766981 21.9214233019
BTBR T+ Itpr3tf/J both 5.25 7.1604027485 19.430802429 -8.930802429
BXD11/TyJ both 8.0 7.1604027485 22.180802429 -6.180802429
BXD1/TyJ both 36.8333333333 6.5365235103 49.7785756231 23.8880910436
BXD2/TyJ both 35.6666666667 5.8464443623 47.2452433647 24.0880899686
BXD31/TyJ both 23.9583333333 5.4688479336 34.789100091 13.1275665757
BXD38/TyJ both 36.1666666667 6.5365235103 49.1119089564 23.2214243769
BXD42/TyJ both 23.5833333333 6.5365235103 36.5285756231 10.6380910436
BXD48a/RwwJ both 32.3333333333 6.5365235103 45.2785756231 19.3880910436
BXD62/RwwJ both 13.8333333333 6.5365235103 26.7785756231 0.8880910436
BXD65/RwwJ both 35.1666666667 5.8464443623 46.7452433647 23.5880899686
BXD77/RwwJ both 27.3333333333 6.5365235103 40.2785756231 14.3880910436
BXD84/RwwJ both 22.0 5.8464443623 33.5785766981 10.4214233019
BXD98/RwwJ both 37.0833333333 6.5365235103 50.0285756231 24.1380910436
C3HeB/FeJ both 24.5 7.1604027485 38.680802429 10.319197571
C3H/HeJ both 2.0833333333 6.5365235103 15.0285756231 -10.8619089564
C57BL/10J both 24.1666666667 5.8464443623 35.7452433647 12.5880899686
C57BL/6J both 20.625 6.2010906816 32.9059351495 8.3440648505
C57BLKS/J both 22.1666666667 6.5365235103 35.1119089564 9.2214243769
C57BR/cdJ both 34.6666666667 5.8464443623 46.2452433647 23.0880899686
C58/J both 38.8333333333 5.8464443623 50.4119100314 27.2547566353
CBA/J both 7.0 5.8464443623 18.5785766981 -4.5785766981
FVB/NJ both 4.0833333333 6.5365235103 17.0285756231 -8.8619089564
LP/J both 25.5 7.1604027485 39.680802429 11.319197571
MA/MyJ both 36.6666666667 5.8464443623 48.2452433647 25.0880899686
MRL/MpJ both 17.6666666667 6.5365235103 30.6119089564 4.7214243769
NOD/ShiLtJ both 38.6666666667 5.8464443623 50.2452433647 27.0880899686
NZB/BlNJ both 10.5833333333 6.5365235103 23.5285756231 -2.3619089564
NZO/HlLtJ both 18.0 5.8464443623 29.5785766981 6.4214233019
NZW/LacJ both 12.75 7.1604027485 26.930802429 -1.430802429
SM/J both 19.5 5.0631693395 29.5273415602 9.4726584398




  GWAS USING LINEAR MIXED MODELS