Project measure / variable:   Project1032   inactive_d7_cocaine

ID, description, units MPD:111508   inactive_d7_cocaine   number of inactive lever presses (intravenous self administration), cocaine   [n]  day 7  
cocaine study
Data set, strains Project1032   HMDP   66 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of inactive lever presses (intravenous self administration), cocaine day 7



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested59 strains58 strains
Mean of the strain means10.76   n 52.01   n
Median of the strain means4.0   n 5.0   n
SD of the strain means± 18.08 ± 207.2
Coefficient of variation (CV)1.6802 3.9839
Min–max range of strain means1.0   –   112.7   n 1.0   –   1340.0   n
Mean sample size per strain1.8   mice 2.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 68696.707 68696.707 1.1343 0.2902
strain 23 1253889.5819 54516.9383 0.9001 0.5978
sex:strain 23 858694.8375 37334.5582 0.6164 0.9042
Residuals 76 4602962.8333 60565.3004


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.25
129X1/SvJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
129X1/SvJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.25
A/J f 14.0 15.556   2   11.0 1.1112 3.0, 25.0 0.18
A/J m 9.0 11.314   2   8.0 1.2571 1.0, 17.0 -0.21
AKR/J f 3.0 0.0   2   0.0 0.0 3.0, 3.0 -0.43
AKR/J m 2.0 1.7321   3 1.0 0.866 1.0, 4.0 -0.24
BALB/cByJ f 4.3333 4.9329   3 2.848 1.1384 1.0, 10.0 -0.36
BALB/cByJ m 11.0 11.314   2   8.0 1.0285 3.0, 19.0 -0.2
BALB/cJ f 22.0 25.456   2   18.0 1.1571 4.0, 40.0 0.62
BALB/cJ m 9.0 10.583   3 6.1101 1.1759 1.0, 21.0 -0.21
BPL/1J f 52.33 47.543   3 27.449 0.9085 6.0, 101.0 2.3
BPL/1J m 68.33 90.94   3 52.51 1.3308 2.0, 172.0 0.08
BTBR T+ Itpr3tf/J f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.54
BXD100/RwwJ f 13.0 0.0   1   0.0 0.0 13.0, 13.0 0.12
BXD100/RwwJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.23
BXD11/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
BXD11/TyJ m 166.0 233.3   2   165.0 1.4057 1.0, 331.0 0.55
BXD15/TyJ f 5.0 1.4142   2   1.0 0.2828 4.0, 6.0 -0.32
BXD15/TyJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.24
BXD1/TyJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.22
BXD21/TyJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.48
BXD21/TyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.25
BXD28/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
BXD2/TyJ f 22.333 21.825   3 12.601 0.9772 3.0, 46.0 0.64
BXD2/TyJ m 178.7 303.4   3 175.2 1.6981 3.0, 529.0 0.61
BXD31/TyJ f 3.5 3.5355   2   2.5 1.0102 1.0, 6.0 -0.4
BXD31/TyJ m 6.5 5.8023   4 2.9011 0.8927 1.0, 12.0 -0.22
BXD32/TyJ f 5.5 2.1213   2   1.5 0.3857 4.0, 7.0 -0.29
BXD32/TyJ m 5.0 2.6458   3 1.5275 0.5292 2.0, 7.0 -0.23
BXD34/TyJ f 7.5 6.364   2   4.5 0.8485 3.0, 12.0 -0.18
BXD34/TyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.25
BXD38/TyJ f 12.0 4.0   3 2.3094 0.3333 8.0, 16.0 0.07
BXD38/TyJ m 28.5 37.477   2   26.5 1.315 2.0, 55.0 -0.11
BXD39/TyJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.32
BXD39/TyJ m 4.5 4.9497   2   3.5 1.0999 1.0, 8.0 -0.23
BXD40/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
BXD42/TyJ f 66.0 86.27   2   61.0 1.3071 5.0, 127.0 3.06
BXD42/TyJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.24
BXD48a/RwwJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.54
BXD48a/RwwJ m 15.667 17.474   3 10.088 1.1153 1.0, 35.0 -0.18
BXD50/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
BXD50/RwwJ m 5.5 3.5355   2   2.5 0.6428 3.0, 8.0 -0.22
BXD55/RwwJ f 16.0 0.0   1   0.0 0.0 16.0, 16.0 0.29
BXD55/RwwJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.21
BXD56/RwwJ m 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.24
BXD60/RwwJ m 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.21
BXD61/RwwJ f 13.0 0.0   1   0.0 0.0 13.0, 13.0 0.12
BXD62/RwwJ f 1.6667 1.1547   3 0.66667 0.6928 1.0, 3.0 -0.5
BXD62/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.25
BXD63/RwwJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.24
BXD65/RwwJ f 14.0 11.533   3 6.6583 0.8238 1.0, 23.0 0.18
BXD65/RwwJ m 4.5 2.1213   2   1.5 0.4714 3.0, 6.0 -0.23
BXD68/RwwJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.37
BXD68/RwwJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.24
BXD69/RwwJ f 24.5 24.749   2   17.5 1.0102 7.0, 42.0 0.76
BXD70/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.48
BXD70/RwwJ m 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.23
BXD71/RwwJ f 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.1
BXD71/RwwJ m 11.0 14.142   2   10.0 1.2856 1.0, 21.0 -0.2
BXD73a/RwwJ f 29.0 0.0   1   0.0 0.0 29.0, 29.0 1.01
BXD73a/RwwJ m 66.0 0.0   1   0.0 0.0 66.0, 66.0 0.07
BXD75/RwwJ f 22.0 0.0   1   0.0 0.0 22.0, 22.0 0.62
BXD75/RwwJ m 4.5 2.1213   2   1.5 0.4714 3.0, 6.0 -0.23
BXD77/RwwJ f 15.0 16.971   2   12.0 1.1314 3.0, 27.0 0.23
BXD77/RwwJ m 3.0 2.8284   2   2.0 0.9428 1.0, 5.0 -0.24
BXD84/RwwJ f 9.0 8.4853   2   6.0 0.9428 3.0, 15.0 -0.1
BXD84/RwwJ m 3.3333 2.0817   3 1.2019 0.6245 1.0, 5.0 -0.23
BXD90/RwwJ m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.18
BXD98/RwwJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
BXD98/RwwJ m 2.0 1.0   3 0.57735 0.5 1.0, 3.0 -0.24
BXD99/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.48
C3HeB/FeJ f 8.5 3.5355   2   2.5 0.4159 6.0, 11.0 -0.13
C3HeB/FeJ m 9.0 5.6569   2   4.0 0.6285 5.0, 13.0 -0.21
C3H/HeJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.48
C3H/HeJ m 12.667 18.502   3 10.682 1.4607 1.0, 34.0 -0.19
C57BL/10J f 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.4
C57BL/10J m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.24
C57BL/6J f 4.0 4.2426   2   3.0 1.0607 1.0, 7.0 -0.37
C57BL/6J m 2.3333 1.5275   3 0.88192 0.6547 1.0, 4.0 -0.24
C57BLKS/J f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.51
C57BLKS/J m 1.3333 0.57735   3 0.33333 0.433 1.0, 2.0 -0.24
C57BR/cdJ f 7.6667 8.3267   3 4.8074 1.0861 1.0, 17.0 -0.17
C57BR/cdJ m 2.6667 1.5275   3 0.88192 0.5728 1.0, 4.0 -0.24
C57L/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
C57L/J m 5.0 1.0   3 0.57735 0.2 4.0, 6.0 -0.23
C58/J f 3.0 3.4641   3 2.0 1.1547 1.0, 7.0 -0.43
C58/J m 5.3333 3.2146   3 1.8559 0.6027 3.0, 9.0 -0.23
CBA/J f 5.5 3.5355   2   2.5 0.6428 3.0, 8.0 -0.29
CBA/J m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.24
DBA/1J f 2.3333 1.1547   3 0.66667 0.4949 1.0, 3.0 -0.47
DBA/1J m 2.0 0.0   2   0.0 0.0 2.0, 2.0 -0.24
DBA/2J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
FVB/NJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 0.35
FVB/NJ m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.23
I/LnJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.22
KK/HlJ f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.51
KK/HlJ m 12.0 12.124   3 7.0 1.0104 5.0, 26.0 -0.19
LP/J f 16.0 0.0   1   0.0 0.0 16.0, 16.0 0.29
LP/J m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.24
MA/MyJ f 112.7 148.4   3 85.65 1.3167 1.0, 281.0 5.64
MA/MyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.25
MRL/MpJ f 3.0 1.4142   2   1.0 0.4714 2.0, 4.0 -0.43
MRL/MpJ m 5.0 5.6569   2   4.0 1.1314 1.0, 9.0 -0.23
NOD/ShiLtJ f 23.0 15.716   3 9.0738 0.6833 9.0, 40.0 0.68
NOD/ShiLtJ m 27.5 36.062   2   25.5 1.3114 2.0, 53.0 -0.12
NZB/BlNJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.54
NZB/BlNJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.25
NZO/HlLtJ f 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.46
NZO/HlLtJ m 857.3 1481.0   3 855.3 1.728 1.0, 2568.0 3.89
NZW/LacJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
NZW/LacJ m 36.333 61.2   3 35.333 1.6844 1.0, 107.0 -0.08
PL/J f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.26
PL/J m 1340.0 2237.0   3 1292.0 1.6696 8.0, 3923.0 6.22
SJL/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
SM/J f 3.5 2.3805   4 1.1902 0.6801 1.0, 6.0 -0.4
SM/J m 9.5 14.387   4 7.1937 1.5145 1.0, 31.0 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 14.0 174.0191087763 360.5890925045 -332.5890925045
A/J m 9.0 174.0191087763 355.5890925045 -337.5890925045
AKR/J f 3.0 174.0191087763 349.5890925045 -343.5890925045
AKR/J m 2.0 142.0860073319 284.9888090168 -280.9888090168
BALB/cByJ f 4.3333333333 142.0860073319 287.3221423501 -278.6554756835
BALB/cByJ m 11.0 174.0191087763 357.5890925045 -335.5890925045
BALB/cJ f 22.0 174.0191087763 368.5890925045 -324.5890925045
BALB/cJ m 9.0 142.0860073319 291.9888090168 -273.9888090168
BPL/1J f 52.3333333333 142.0860073319 335.3221423501 -230.6554756835
BPL/1J m 68.3333333333 142.0860073319 351.3221423501 -214.6554756835
BXD2/TyJ f 22.3333333333 142.0860073319 305.3221423501 -260.6554756835
BXD2/TyJ m 178.6666666667 142.0860073319 461.6554756835 -104.3221423501
BXD31/TyJ f 3.5 174.0191087763 350.0890925045 -343.0890925045
BXD31/TyJ m 6.5 123.0500918718 251.5754975952 -238.5754975952
BXD32/TyJ f 5.5 174.0191087763 352.0890925045 -341.0890925045
BXD32/TyJ m 5.0 142.0860073319 287.9888090168 -277.9888090168
BXD38/TyJ f 12.0 142.0860073319 294.9888090168 -270.9888090168
BXD38/TyJ m 28.5 174.0191087763 375.0890925045 -318.0890925045
BXD48a/RwwJ f 1.0 174.0191087763 347.5890925045 -345.5890925045
BXD48a/RwwJ m 15.6666666667 142.0860073319 298.6554756835 -267.3221423501
BXD65/RwwJ f 14.0 142.0860073319 296.9888090168 -268.9888090168
BXD65/RwwJ m 4.5 174.0191087763 351.0890925045 -342.0890925045
BXD77/RwwJ f 15.0 174.0191087763 361.5890925045 -331.5890925045
BXD77/RwwJ m 3.0 174.0191087763 349.5890925045 -343.5890925045
BXD84/RwwJ f 9.0 174.0191087763 355.5890925045 -337.5890925045
BXD84/RwwJ m 3.3333333333 142.0860073319 286.3221423501 -279.6554756835
C3HeB/FeJ f 8.5 174.0191087763 355.0890925045 -338.0890925045
C3HeB/FeJ m 9.0 174.0191087763 355.5890925045 -337.5890925045
C57BL/6J f 4.0 174.0191087763 350.5890925045 -342.5890925045
C57BL/6J m 2.3333333333 142.0860073319 285.3221423501 -280.6554756835
C57BLKS/J f 1.5 174.0191087763 348.0890925045 -345.0890925045
C57BLKS/J m 1.3333333333 142.0860073319 284.3221423501 -281.6554756835
C57BR/cdJ f 7.6666666667 142.0860073319 290.6554756835 -275.3221423501
C57BR/cdJ m 2.6666666667 142.0860073319 285.6554756835 -280.3221423501
C58/J f 3.0 142.0860073319 285.9888090168 -279.9888090168
C58/J m 5.3333333333 142.0860073319 288.3221423501 -277.6554756835
DBA/1J f 2.3333333333 142.0860073319 285.3221423501 -280.6554756835
DBA/1J m 2.0 174.0191087763 348.5890925045 -344.5890925045
KK/HlJ f 1.5 174.0191087763 348.0890925045 -345.0890925045
KK/HlJ m 12.0 142.0860073319 294.9888090168 -270.9888090168
MRL/MpJ f 3.0 174.0191087763 349.5890925045 -343.5890925045
MRL/MpJ m 5.0 174.0191087763 351.5890925045 -341.5890925045
NOD/ShiLtJ f 23.0 142.0860073319 305.9888090168 -259.9888090168
NOD/ShiLtJ m 27.5 174.0191087763 374.0890925045 -319.0890925045
NZO/HlLtJ f 2.5 174.0191087763 349.0890925045 -344.0890925045
NZO/HlLtJ m 857.3333333333 142.0860073319 1140.3221423501 574.3445243165
SM/J f 3.5 123.0500918718 248.5754975952 -241.5754975952
SM/J m 9.5 123.0500918718 254.5754975952 -235.5754975952


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 11.5 123.0500918718 256.5754975952 -233.5754975952
AKR/J both 2.5 112.3288517021 226.2222972079 -221.2222972079
BALB/cByJ both 7.6666666667 112.3288517021 231.3889638745 -216.0556305412
BALB/cJ both 15.5 112.3288517021 239.2222972079 -208.2222972079
BPL/1J both 60.3333333333 100.4699792961 260.436639189 -139.7699725223
BXD2/TyJ both 100.5 100.4699792961 300.6033058557 -99.6033058557
BXD31/TyJ both 5.0 106.564505499 217.2416067626 -207.2416067626
BXD32/TyJ both 5.25 112.3288517021 228.9722972079 -218.4722972079
BXD38/TyJ both 20.25 112.3288517021 243.9722972079 -203.4722972079
BXD48a/RwwJ both 8.3333333333 112.3288517021 232.0556305412 -215.3889638745
BXD65/RwwJ both 9.25 112.3288517021 232.9722972079 -214.4722972079
BXD77/RwwJ both 9.0 123.0500918718 254.0754975952 -236.0754975952
BXD84/RwwJ both 6.1666666667 112.3288517021 229.8889638745 -217.5556305412
C3HeB/FeJ both 8.75 123.0500918718 253.8254975952 -236.3254975952
C57BL/6J both 3.1666666667 112.3288517021 226.8889638745 -220.5556305412
C57BLKS/J both 1.4166666667 112.3288517021 225.1389638745 -222.3056305412
C57BR/cdJ both 5.1666666667 100.4699792961 205.2699725223 -194.936639189
C58/J both 4.1666666667 100.4699792961 204.2699725223 -195.936639189
DBA/1J both 2.1666666667 112.3288517021 225.8889638745 -221.5556305412
KK/HlJ both 6.75 112.3288517021 230.4722972079 -216.9722972079
MRL/MpJ both 4.0 123.0500918718 249.0754975952 -241.0754975952
NOD/ShiLtJ both 25.25 112.3288517021 248.9722972079 -198.4722972079
NZO/HlLtJ both 429.9166666667 112.3288517021 653.6389638745 206.1943694588
SM/J both 6.5 87.0095543882 179.7945462523 -166.7945462523




  GWAS USING LINEAR MIXED MODELS