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Project measure / variable:   Project1032   active_pct_d9_cocaine

ID, description, units MPD:111458   active_pct_d9_cocaine   percentage of lever presses that are active (intravenous self administration), cocaine   [%]  day 9  
cocaine study
Data set, strains Project1032   HMDP   65 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - percentage of lever presses that are active (intravenous self administration), cocaine day 9



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested61 strains61 strains
Mean of the strain means82.44   % 79.46   %
Median of the strain means87.5   % 83.3   %
SD of the strain means± 15.686 ± 19.042
Coefficient of variation (CV)0.1903 0.2396
Min–max range of strain means41.8   –   100.0   % 13.6   –   100.0   %
Mean sample size per strain2.1   mice 2.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 871.4288 871.4288 2.0893 0.1512
strain 32 23081.6655 721.302 1.7293 0.0197
sex:strain 32 20860.924 651.9039 1.563 0.0468
Residuals 109 45463.5617 417.0969


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.12
129S1/SvImJ m 87.55 14.071   2   9.95 0.1607 77.6, 97.5 0.42
129X1/SvJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.12
A/J f 83.1 16.076   3 9.2813 0.1935 68.0, 100.0 0.04
A/J m 80.0 0.0   1   0.0 0.0 80.0, 80.0 0.03
AKR/J f 65.65 45.75   2   32.35 0.6969 33.3, 98.0 -1.07
AKR/J m 96.2 0.56569   2   0.4 0.0059 95.8, 96.6 0.88
BALB/cByJ f 90.1 8.9011   3 5.1391 0.0988 80.0, 96.8 0.49
BALB/cByJ m 86.6 19.443   3 11.225 0.2245 64.3, 100.0 0.37
BALB/cJ f 80.3 22.486   2   15.9 0.28 64.4, 96.2 -0.14
BALB/cJ m 83.8 14.674   3 8.4719 0.1751 71.4, 100.0 0.23
BPL/1J f 63.43 33.923   3 19.585 0.5348 31.3, 98.9 -1.21
BPL/1J m 70.03 22.837   3 13.185 0.3261 50.0, 94.9 -0.5
BTBR T+ Itpr3tf/J f 87.5 17.678   2   12.5 0.202 75.0, 100.0 0.32
BTBR T+ Itpr3tf/J m 87.5 17.678   2   12.5 0.202 75.0, 100.0 0.42
BXD100/RwwJ f 85.6 14.991   2   10.6 0.1751 75.0, 96.2 0.2
BXD100/RwwJ m 87.1 0.0   1   0.0 0.0 87.1, 87.1 0.4
BXD11/TyJ f 100.0 0.0   2   0.0 0.0 100.0, 100.0 1.12
BXD11/TyJ m 13.6 0.0   1   0.0 0.0 13.6, 13.6 -3.46
BXD15/TyJ f 92.73 11.479   3 6.6273 0.1238 79.5, 100.0 0.66
BXD15/TyJ m 98.8 0.0   1   0.0 0.0 98.8, 98.8 1.02
BXD1/TyJ f 100.0 0.0   2   0.0 0.0 100.0, 100.0 1.12
BXD1/TyJ m 98.07 3.3486   3 1.9333 0.0341 94.2, 100.0 0.98
BXD21/TyJ f 83.1 0.0   1   0.0 0.0 83.1, 83.1 0.04
BXD21/TyJ m 80.95 18.597   2   13.15 0.2297 67.8, 94.1 0.08
BXD2/TyJ f 41.8 11.234   3 6.4861 0.2688 32.3, 54.2 -2.59
BXD2/TyJ m 88.73 15.005   3 8.6634 0.1691 71.7, 100.0 0.49
BXD31/TyJ f 94.8 9.0067   3 5.2 0.095 84.4, 100.0 0.79
BXD31/TyJ m 80.53 11.735   4 5.8673 0.1457 71.0, 97.5 0.06
BXD32/TyJ f 83.75 5.3033   2   3.75 0.0633 80.0, 87.5 0.08
BXD32/TyJ m 94.5 3.3941   2   2.4 0.0359 92.1, 96.9 0.79
BXD34/TyJ f 91.15 7.1418   2   5.05 0.0784 86.1, 96.2 0.56
BXD34/TyJ m 73.9 0.0   1   0.0 0.0 73.9, 73.9 -0.29
BXD38/TyJ f 88.3 4.3715   3 2.5239 0.0495 84.2, 92.9 0.37
BXD38/TyJ m 74.77 32.708   3 18.884 0.4375 37.0, 93.9 -0.25
BXD39/TyJ f 70.0 0.0   1   0.0 0.0 70.0, 70.0 -0.79
BXD39/TyJ m 91.93 10.849   3 6.2635 0.118 79.6, 100.0 0.65
BXD40/TyJ m 97.8 3.1113   2   2.2 0.0318 95.6, 100.0 0.96
BXD42/TyJ f 74.35 27.082   2   19.15 0.3643 55.2, 93.5 -0.52
BXD42/TyJ m 99.13 1.5011   3 0.86667 0.0151 97.4, 100.0 1.03
BXD48a/RwwJ f 94.65 7.566   2   5.35 0.0799 89.3, 100.0 0.78
BXD48a/RwwJ m 68.07 32.931   3 19.013 0.4838 31.8, 96.1 -0.6
BXD50/RwwJ f 88.9 0.0   1   0.0 0.0 88.9, 88.9 0.41
BXD50/RwwJ m 65.15 41.649   2   29.45 0.6393 35.7, 94.6 -0.75
BXD55/RwwJ f 89.35 15.061   2   10.65 0.1686 78.7, 100.0 0.44
BXD55/RwwJ m 52.7 0.0   1   0.0 0.0 52.7, 52.7 -1.41
BXD56/RwwJ m 50.0 0.0   1   0.0 0.0 50.0, 50.0 -1.55
BXD60/RwwJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.12
BXD60/RwwJ m 92.55 10.536   2   7.45 0.1138 85.1, 100.0 0.69
BXD61/RwwJ f 91.6 7.4706   3 4.3132 0.0816 85.7, 100.0 0.58
BXD61/RwwJ m 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.08
BXD62/RwwJ f 90.7 5.2326   2   3.7 0.0577 87.0, 94.4 0.53
BXD62/RwwJ m 88.45 16.334   2   11.55 0.1847 76.9, 100.0 0.47
BXD63/RwwJ m 77.3 0.0   1   0.0 0.0 77.3, 77.3 -0.11
BXD65/RwwJ f 91.93 8.4198   3 4.8612 0.0916 83.2, 100.0 0.61
BXD65/RwwJ m 95.7 5.009   3 2.8919 0.0523 90.2, 100.0 0.85
BXD68/RwwJ f 58.7 0.0   1   0.0 0.0 58.7, 58.7 -1.51
BXD68/RwwJ m 82.75 24.395   2   17.25 0.2948 65.5, 100.0 0.17
BXD69/RwwJ f 63.15 30.476   2   21.55 0.4826 41.6, 84.7 -1.23
BXD70/RwwJ f 50.0 0.0   1   0.0 0.0 50.0, 50.0 -2.07
BXD70/RwwJ m 66.65 47.164   2   33.35 0.7076 33.3, 100.0 -0.67
BXD71/RwwJ f 78.9 0.0   1   0.0 0.0 78.9, 78.9 -0.23
BXD71/RwwJ m 75.7 34.365   2   24.3 0.454 51.4, 100.0 -0.2
BXD73a/RwwJ f 91.95 11.384   2   8.05 0.1238 83.9, 100.0 0.61
BXD73a/RwwJ m 17.2 0.0   1   0.0 0.0 17.2, 17.2 -3.27
BXD75/RwwJ f 70.6 0.0   1   0.0 0.0 70.6, 70.6 -0.75
BXD75/RwwJ m 70.5 4.5255   2   3.2 0.0642 67.3, 73.7 -0.47
BXD77/RwwJ f 71.5 12.021   2   8.5 0.1681 63.0, 80.0 -0.7
BXD77/RwwJ m 89.15 15.344   2   10.85 0.1721 78.3, 100.0 0.51
BXD84/RwwJ f 82.23 16.762   3 9.6775 0.2038 66.7, 100.0 -0.01
BXD84/RwwJ m 77.67 16.738   3 9.6639 0.2155 63.2, 96.0 -0.09
BXD90/RwwJ m 90.7 2.5456   2   1.8 0.0281 88.9, 92.5 0.59
BXD98/RwwJ f 95.85 5.869   2   4.15 0.0612 91.7, 100.0 0.86
BXD98/RwwJ m 99.07 1.6166   3 0.93333 0.0163 97.2, 100.0 1.03
BXD99/RwwJ f 72.2 0.0   1   0.0 0.0 72.2, 72.2 -0.65
BXD99/RwwJ m 83.3 0.0   1   0.0 0.0 83.3, 83.3 0.2
C3HeB/FeJ f 54.5 3.677   2   2.6 0.0675 51.9, 57.1 -1.78
C3HeB/FeJ m 95.1 6.9296   2   4.9 0.0729 90.2, 100.0 0.82
C3H/HeJ f 55.53 25.455   3 14.697 0.4584 33.3, 83.3 -1.72
C3H/HeJ m 80.25 27.931   2   19.75 0.348 60.5, 100.0 0.04
C57BL/10J f 81.07 10.508   3 6.0667 0.1296 75.0, 93.2 -0.09
C57BL/10J m 96.07 3.4588   3 1.9969 0.036 93.5, 100.0 0.87
C57BL/6J f 90.9 0.0   1   0.0 0.0 90.9, 90.9 0.54
C57BL/6J m 85.43 19.873   3 11.474 0.2326 62.5, 97.6 0.31
C57BLKS/J f 50.3 41.55   3 23.989 0.826 8.7, 91.8 -2.05
C57BLKS/J m 98.7 1.8385   2   1.3 0.0186 97.4, 100.0 1.01
C57BR/cdJ f 87.5 14.123   3 8.1541 0.1614 71.4, 97.8 0.32
C57BR/cdJ m 95.87 4.4242   3 2.5543 0.0461 91.2, 100.0 0.86
C57L/J f 98.9 0.0   1   0.0 0.0 98.9, 98.9 1.05
C57L/J m 83.07 6.176   3 3.5657 0.0744 76.3, 88.4 0.19
C58/J f 95.43 4.4095   3 2.5458 0.0462 91.2, 100.0 0.83
C58/J m 93.6 6.1733   3 3.5642 0.066 86.5, 97.7 0.74
CBA/J f 81.2 20.889   3 12.06 0.2572 57.1, 94.1 -0.08
CBA/J m 97.9 2.0075   3 1.159 0.0205 96.0, 100.0 0.97
DBA/1J f 96.3 6.4086   3 3.7 0.0665 88.9, 100.0 0.88
DBA/1J m 50.0 0.0   1   0.0 0.0 50.0, 50.0 -1.55
DBA/2J f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.12
FVB/NJ f 56.9 0.0   1   0.0 0.0 56.9, 56.9 -1.63
FVB/NJ m 63.25 1.0607   2   0.75 0.0168 62.5, 64.0 -0.85
I/LnJ f 97.35 0.35355   2   0.25 0.0036 97.1, 97.6 0.95
I/LnJ m 63.3 0.0   1   0.0 0.0 63.3, 63.3 -0.85
KK/HlJ f 89.85 10.819   2   7.65 0.1204 82.2, 97.5 0.47
KK/HlJ m 62.9 5.374   2   3.8 0.0854 59.1, 66.7 -0.87
LP/J f 97.2 3.9598   2   2.8 0.0407 94.4, 100.0 0.94
LP/J m 95.95 2.6163   2   1.85 0.0273 94.1, 97.8 0.87
MA/MyJ f 66.43 40.161   3 23.187 0.6045 20.8, 96.4 -1.02
MA/MyJ m 100.0 0.0   3 0.0 0.0 100.0, 100.0 1.08
MRL/MpJ f 84.7 16.405   2   11.6 0.1937 73.1, 96.3 0.14
MRL/MpJ m 86.67 23.094   3 13.333 0.2665 60.0, 100.0 0.38
NOD/ShiLtJ f 46.0 26.376   3 15.228 0.5734 29.2, 76.4 -2.32
NOD/ShiLtJ m 53.53 36.548   3 21.101 0.6827 28.7, 95.5 -1.36
NZB/BlNJ f 100.0 0.0   1   0.0 0.0 100.0, 100.0 1.12
NZB/BlNJ m 81.43 24.398   3 14.086 0.2996 53.8, 100.0 0.1
NZO/HlLtJ f 91.0 12.211   3 7.0501 0.1342 77.1, 100.0 0.55
NZO/HlLtJ m 71.37 40.851   3 23.585 0.5724 24.2, 95.5 -0.42
NZW/LacJ f 95.9 5.7983   2   4.1 0.0605 91.8, 100.0 0.86
NZW/LacJ m 78.83 34.519   3 19.93 0.4379 39.0, 100.0 -0.03
PL/J f 96.5 4.9497   2   3.5 0.0513 93.0, 100.0 0.9
PL/J m 33.433 23.313   3 13.46 0.6973 13.8, 59.2 -2.42
SJL/J f 81.25 26.517   2   18.75 0.3264 62.5, 100.0 -0.08
SM/J f 75.97 30.434   4 15.217 0.4006 32.1, 100.0 -0.41
SM/J m 66.35 31.789   4 15.894 0.4791 33.9, 95.5 -0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AKR/J f 65.65 14.4412065982 94.2720019902 37.0279980098
AKR/J m 96.2 14.4412065982 124.8220019902 67.5779980098
BALB/cByJ f 90.1 11.7911958119 113.4697667643 66.7302332357
BALB/cByJ m 86.6 11.7911958119 109.9697667643 63.2302332357
BALB/cJ f 80.3 14.4412065982 108.9220019902 51.6779980098
BALB/cJ m 83.8 11.7911958119 107.1697667643 60.4302332357
BPL/1J f 63.4333333333 11.7911958119 86.8031000977 40.063566569
BPL/1J m 70.0333333333 11.7911958119 93.4031000977 46.663566569
BTBR T+ Itpr3tf/J f 87.5 14.4412065982 116.1220019902 58.8779980098
BTBR T+ Itpr3tf/J m 87.5 14.4412065982 116.1220019902 58.8779980098
BXD1/TyJ f 100.0 14.4412065982 128.6220019902 71.3779980098
BXD1/TyJ m 98.0666666667 11.7911958119 121.436433431 74.6968999023
BXD2/TyJ f 41.8 11.7911958119 65.1697667643 18.4302332357
BXD2/TyJ m 88.7333333333 11.7911958119 112.1031000977 65.363566569
BXD31/TyJ f 94.8 11.7911958119 118.1697667643 71.4302332357
BXD31/TyJ m 80.525 10.2114751141 100.7638116984 60.2861883016
BXD32/TyJ f 83.75 14.4412065982 112.3720019902 55.1279980098
BXD32/TyJ m 94.5 14.4412065982 123.1220019902 65.8779980098
BXD38/TyJ f 88.3 11.7911958119 111.6697667643 64.9302332357
BXD38/TyJ m 74.7666666667 11.7911958119 98.136433431 51.3968999023
BXD42/TyJ f 74.35 14.4412065982 102.9720019902 45.7279980098
BXD42/TyJ m 99.1333333333 11.7911958119 122.5031000977 75.763566569
BXD48a/RwwJ f 94.65 14.4412065982 123.2720019902 66.0279980098
BXD48a/RwwJ m 68.0666666667 11.7911958119 91.436433431 44.6968999023
BXD62/RwwJ f 90.7 14.4412065982 119.3220019902 62.0779980098
BXD62/RwwJ m 88.45 14.4412065982 117.0720019902 59.8279980098
BXD65/RwwJ f 91.9333333333 11.7911958119 115.3031000977 68.563566569
BXD65/RwwJ m 95.7 11.7911958119 119.0697667643 72.3302332357
BXD77/RwwJ f 71.5 14.4412065982 100.1220019902 42.8779980098
BXD77/RwwJ m 89.15 14.4412065982 117.7720019902 60.5279980098
BXD84/RwwJ f 82.2333333333 11.7911958119 105.6031000977 58.863566569
BXD84/RwwJ m 77.6666666667 11.7911958119 101.036433431 54.2968999023
BXD98/RwwJ f 95.85 14.4412065982 124.4720019902 67.2279980098
BXD98/RwwJ m 99.0666666667 11.7911958119 122.436433431 75.6968999023
C3HeB/FeJ f 54.5 14.4412065982 83.1220019902 25.8779980098
C3HeB/FeJ m 95.1 14.4412065982 123.7220019902 66.4779980098
C3H/HeJ f 55.5333333333 11.7911958119 78.9031000977 32.163566569
C3H/HeJ m 80.25 14.4412065982 108.8720019902 51.6279980098
C57BL/10J f 81.0666666667 11.7911958119 104.436433431 57.6968999023
C57BL/10J m 96.0666666667 11.7911958119 119.436433431 72.6968999023
C57BLKS/J f 50.3 11.7911958119 73.6697667643 26.9302332357
C57BLKS/J m 98.7 14.4412065982 127.3220019902 70.0779980098
C57BR/cdJ f 87.5 11.7911958119 110.8697667643 64.1302332357
C57BR/cdJ m 95.8666666667 11.7911958119 119.236433431 72.4968999023
C58/J f 95.4333333333 11.7911958119 118.8031000977 72.063566569
C58/J m 93.6 11.7911958119 116.9697667643 70.2302332357
CBA/J f 81.2 11.7911958119 104.5697667643 57.8302332357
CBA/J m 97.9 11.7911958119 121.2697667643 74.5302332357
KK/HlJ f 89.85 14.4412065982 118.4720019902 61.2279980098
KK/HlJ m 62.9 14.4412065982 91.5220019902 34.2779980098
LP/J f 97.2 14.4412065982 125.8220019902 68.5779980098
LP/J m 95.95 14.4412065982 124.5720019902 67.3279980098
MA/MyJ f 66.4333333333 11.7911958119 89.8031000977 43.063566569
MA/MyJ m 100.0 11.7911958119 123.3697667643 76.6302332357
MRL/MpJ f 84.7 14.4412065982 113.3220019902 56.0779980098
MRL/MpJ m 86.6666666667 11.7911958119 110.036433431 63.2968999023
NOD/ShiLtJ f 46.0 11.7911958119 69.3697667643 22.6302332357
NOD/ShiLtJ m 53.5333333333 11.7911958119 76.9031000977 30.163566569
NZO/HlLtJ f 91.0 11.7911958119 114.3697667643 67.6302332357
NZO/HlLtJ m 71.3666666667 11.7911958119 94.736433431 47.9968999023
NZW/LacJ f 95.9 14.4412065982 124.5220019902 67.2779980098
NZW/LacJ m 78.8333333333 11.7911958119 102.2031000977 55.463566569
PL/J f 96.5 14.4412065982 125.1220019902 67.8779980098
PL/J m 33.4333333333 11.7911958119 56.8031000977 10.063566569
SM/J f 75.975 10.2114751141 96.2138116984 55.7361883016
SM/J m 66.35 10.2114751141 86.5888116984 46.1111883016


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
AKR/J both 80.925 10.2114751141 101.1638116984 60.6861883016
BALB/cByJ both 88.35 8.3376345169 104.8749205538 71.8250794462
BALB/cJ both 82.05 9.3217587757 100.5254228405 63.5745771595
BPL/1J both 66.7333333333 8.3376345169 83.2582538871 50.2084127795
BTBR T+ Itpr3tf/J both 87.5 10.2114751141 107.7388116984 67.2611883016
BXD1/TyJ both 99.0333333333 9.3217587757 117.5087561739 80.5579104928
BXD2/TyJ both 65.2666666667 8.3376345169 81.7915872205 48.7417461129
BXD31/TyJ both 87.6625 7.7991429446 103.120147764 72.204852236
BXD32/TyJ both 89.125 10.2114751141 109.3638116984 68.8861883016
BXD38/TyJ both 81.5333333333 8.3376345169 98.0582538871 65.0084127795
BXD42/TyJ both 86.7416666667 9.3217587757 105.2170895072 68.2662438261
BXD48a/RwwJ both 81.3583333333 9.3217587757 99.8337561739 62.8829104928
BXD62/RwwJ both 89.575 10.2114751141 109.8138116984 69.3361883016
BXD65/RwwJ both 93.8166666667 8.3376345169 110.3415872205 77.2917461129
BXD77/RwwJ both 80.325 10.2114751141 100.5638116984 60.0861883016
BXD84/RwwJ both 79.95 8.3376345169 96.4749205538 63.4250794462
BXD98/RwwJ both 97.4583333333 9.3217587757 115.9337561739 78.9829104928
C3HeB/FeJ both 74.8 10.2114751141 95.0388116984 54.5611883016
C3H/HeJ both 67.8916666667 9.3217587757 86.3670895072 49.4162438261
C57BL/10J both 88.5666666667 8.3376345169 105.0915872205 72.0417461129
C57BLKS/J both 74.5 9.3217587757 92.9754228405 56.0245771595
C57BR/cdJ both 91.6833333333 8.3376345169 108.2082538871 75.1584127795
C58/J both 94.5166666667 8.3376345169 111.0415872205 77.9917461129
CBA/J both 89.55 8.3376345169 106.0749205538 73.0250794462
KK/HlJ both 76.375 10.2114751141 96.6138116984 56.1361883016
LP/J both 96.575 10.2114751141 116.8138116984 76.3361883016
MA/MyJ both 83.2166666667 8.3376345169 99.7415872205 66.6917461129
MRL/MpJ both 85.6833333333 9.3217587757 104.1587561739 67.2079104928
NOD/ShiLtJ both 49.7666666667 8.3376345169 66.2915872205 33.2417461129
NZO/HlLtJ both 81.1833333333 8.3376345169 97.7082538871 64.6584127795
NZW/LacJ both 87.3666666667 9.3217587757 105.8420895072 68.8912438261
PL/J both 64.9666666667 9.3217587757 83.4420895072 46.4912438261
SM/J both 71.1625 7.2206032991 85.4735009951 56.8514990049




  GWAS USING LINEAR MIXED MODELS