Project measure / variable:   Project1032   inactive_d6_cocaine

ID, description, units MPD:111507   inactive_d6_cocaine   number of inactive lever presses (intravenous self administration), cocaine   [n]  day 6  
cocaine study
Data set, strains Project1032   HMDP   64 strains     sex: both     age: 9-15wks
Procedure operant conditioning chamber
Ontology mappings


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  STRAIN COMPARISON PLOT
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Project1032 - number of inactive lever presses (intravenous self administration), cocaine day 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested55 strains59 strains
Mean of the strain means20.762   n 30.99   n
Median of the strain means5.0   n 6.0   n
SD of the strain means± 54.67 ± 75.68
Coefficient of variation (CV)2.6334 2.4422
Min–max range of strain means1.0   –   326.3   n 1.0   –   421.0   n
Mean sample size per strain2.0   mice 2.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3700.9747 3700.9747 0.606 0.4384
strain 25 155623.8663 6224.9547 1.0193 0.4527
sex:strain 25 145329.9953 5813.1998 0.9519 0.5369
Residuals 87 531293.25 6106.819


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.28
A/J f 10.0 9.8995   2   7.0 0.9899 3.0, 17.0 -0.2
A/J m 8.0 5.6569   2   4.0 0.7071 4.0, 12.0 -0.3
AKR/J f 4.0 0.0   2   0.0 0.0 4.0, 4.0 -0.31
AKR/J m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.36
BALB/cByJ f 22.5 23.335   2   16.5 1.0371 6.0, 39.0 0.03
BALB/cByJ m 6.3333 5.8595   3 3.383 0.9252 2.0, 13.0 -0.33
BALB/cJ f 205.5 285.0   2   201.5 1.3867 4.0, 407.0 3.38
BALB/cJ m 24.667 40.992   3 23.667 1.6618 1.0, 72.0 -0.08
BPL/1J f 81.67 59.75   3 34.498 0.7317 19.0, 138.0 1.11
BPL/1J m 36.0 29.462   3 17.01 0.8184 4.0, 62.0 0.07
BTBR T+ Itpr3tf/J f 1.6667 1.1547   3 0.66667 0.6928 1.0, 3.0 -0.35
BTBR T+ Itpr3tf/J m 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.4
BXD100/RwwJ f 5.0 4.2426   2   3.0 0.8485 2.0, 8.0 -0.29
BXD100/RwwJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.33
BXD11/TyJ m 226.0 0.0   1   0.0 0.0 226.0, 226.0 2.58
BXD15/TyJ f 7.0 8.4853   2   6.0 1.2122 1.0, 13.0 -0.25
BXD15/TyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
BXD1/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.36
BXD1/TyJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.32
BXD21/TyJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.31
BXD21/TyJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.38
BXD28/TyJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.36
BXD2/TyJ f 28.333 10.504   3 6.0645 0.3707 18.0, 39.0 0.14
BXD2/TyJ m 198.7 330.3   3 190.7 1.6624 5.0, 580.0 2.22
BXD31/TyJ f 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.33
BXD31/TyJ m 5.0 3.8297   4 1.9149 0.7659 2.0, 10.0 -0.34
BXD32/TyJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.32
BXD32/TyJ m 6.3333 8.3865   3 4.8419 1.3242 1.0, 16.0 -0.33
BXD34/TyJ f 3.0 0.0   2   0.0 0.0 3.0, 3.0 -0.32
BXD38/TyJ f 11.333 5.5076   3 3.1798 0.486 5.0, 15.0 -0.17
BXD38/TyJ m 167.0 234.8   2   166.0 1.4057 1.0, 333.0 1.8
BXD39/TyJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.27
BXD39/TyJ m 4.0 4.2426   2   3.0 1.0607 1.0, 7.0 -0.36
BXD40/TyJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
BXD42/TyJ f 154.5 202.9   2   143.5 1.3135 11.0, 298.0 2.45
BXD42/TyJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.32
BXD48a/RwwJ f 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.32
BXD48a/RwwJ m 17.333 22.502   3 12.991 1.2982 1.0, 43.0 -0.18
BXD50/RwwJ m 30.5 26.163   2   18.5 0.8578 12.0, 49.0 -0.01
BXD55/RwwJ f 9.0 11.314   2   8.0 1.2571 1.0, 17.0 -0.22
BXD55/RwwJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.21
BXD56/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
BXD60/RwwJ m 5.0 2.8284   2   2.0 0.5657 3.0, 7.0 -0.34
BXD61/RwwJ f 3.0 1.4142   2   1.0 0.4714 2.0, 4.0 -0.32
BXD62/RwwJ f 4.0 1.4142   2   1.0 0.3536 3.0, 5.0 -0.31
BXD62/RwwJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.34
BXD63/RwwJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.4
BXD65/RwwJ f 11.333 12.342   3 7.1259 1.089 1.0, 25.0 -0.17
BXD65/RwwJ m 7.0 4.5826   3 2.6458 0.6547 3.0, 12.0 -0.32
BXD68/RwwJ f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.25
BXD68/RwwJ m 3.0 2.6458   3 1.5275 0.8819 1.0, 6.0 -0.37
BXD69/RwwJ f 25.0 31.113   2   22.0 1.2445 3.0, 47.0 0.08
BXD70/RwwJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.34
BXD70/RwwJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.38
BXD71/RwwJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.32
BXD71/RwwJ m 5.0 5.6569   2   4.0 1.1314 1.0, 9.0 -0.34
BXD73a/RwwJ f 23.5 30.406   2   21.5 1.2939 2.0, 45.0 0.05
BXD73a/RwwJ m 244.0 0.0   1   0.0 0.0 244.0, 244.0 2.81
BXD75/RwwJ f 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.16
BXD75/RwwJ m 5.5 6.364   2   4.5 1.1571 1.0, 10.0 -0.34
BXD77/RwwJ f 3.3333 2.0817   3 1.2019 0.6245 1.0, 5.0 -0.32
BXD77/RwwJ m 7.3333 8.3865   3 4.8419 1.1436 2.0, 17.0 -0.31
BXD84/RwwJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.23
BXD84/RwwJ m 14.0 11.533   3 6.6583 0.8238 2.0, 25.0 -0.22
BXD90/RwwJ m 18.0 16.971   2   12.0 0.9428 6.0, 30.0 -0.17
BXD98/RwwJ f 5.5 6.364   2   4.5 1.1571 1.0, 10.0 -0.28
BXD98/RwwJ m 3.3333 2.3094   3 1.3333 0.6928 2.0, 6.0 -0.37
BXD99/RwwJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.27
BXD99/RwwJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.38
C3HeB/FeJ f 6.0 7.0   3 4.0415 1.1667 1.0, 14.0 -0.27
C3HeB/FeJ m 3.5 0.70711   2   0.5 0.202 3.0, 4.0 -0.36
C3H/HeJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.32
C3H/HeJ m 5.0 5.6569   2   4.0 1.1314 1.0, 9.0 -0.34
C57BL/10J f 5.0 3.4641   3 2.0 0.6928 3.0, 9.0 -0.29
C57BL/10J m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.39
C57BL/6J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.36
C57BL/6J m 4.0 1.4142   2   1.0 0.3536 3.0, 5.0 -0.36
C57BLKS/J f 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -0.35
C57BLKS/J m 3.6667 2.8868   3 1.6667 0.7873 2.0, 7.0 -0.36
C57BR/cdJ f 14.0 17.349   3 10.017 1.2392 3.0, 34.0 -0.12
C57BR/cdJ m 2.0 0.0   2   0.0 0.0 2.0, 2.0 -0.38
C57L/J f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.34
C57L/J m 11.5 13.435   2   9.5 1.1683 2.0, 21.0 -0.26
C58/J f 14.333 16.442   3 9.4927 1.1471 2.0, 33.0 -0.12
C58/J m 7.3333 3.7859   3 2.1858 0.5163 3.0, 10.0 -0.31
CBA/J f 4.3333 3.5119   3 2.0276 0.8104 1.0, 8.0 -0.3
CBA/J m 1.0 0.0   3 0.0 0.0 1.0, 1.0 -0.4
DBA/1J f 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.33
DBA/1J m 1.6667 0.57735   3 0.33333 0.3464 1.0, 2.0 -0.39
DBA/2J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.36
DBA/2J m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.38
FVB/NJ f 5.3333 6.6583   3 3.8442 1.2484 1.0, 13.0 -0.28
FVB/NJ m 7.5 9.1924   2   6.5 1.2257 1.0, 14.0 -0.31
I/LnJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.33
KK/HlJ f 1.3333 0.57735   3 0.33333 0.433 1.0, 2.0 -0.36
KK/HlJ m 9.5 7.7782   2   5.5 0.8188 4.0, 15.0 -0.28
LP/J f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.32
LP/J m 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.38
MA/MyJ f 326.3 521.5   3 301.1 1.5982 3.0, 928.0 5.59
MRL/MpJ f 18.333 24.906   3 14.38 1.3585 2.0, 47.0 -0.04
MRL/MpJ m 3.0 0.0   2   0.0 0.0 3.0, 3.0 -0.37
NOD/ShiLtJ f 38.0 35.086   3 20.257 0.9233 9.0, 77.0 0.32
NOD/ShiLtJ m 25.0 37.269   3 21.517 1.4908 2.0, 68.0 -0.08
NZB/BlNJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.34
NZB/BlNJ m 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.36
NZO/HlLtJ f 4.0 1.4142   2   1.0 0.3536 3.0, 5.0 -0.31
NZO/HlLtJ m 164.7 275.7   3 159.2 1.6743 2.0, 483.0 1.77
NZW/LacJ f 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.33
NZW/LacJ m 28.5 38.891   2   27.5 1.3646 1.0, 56.0 -0.03
PL/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.36
PL/J m 421.0 595.8   3 344.0 1.4152 8.0, 1104.0 5.15
SM/J f 7.25 4.272   4 2.136 0.5892 2.0, 12.0 -0.25
SM/J m 7.0 10.0   4 5.0 1.4286 2.0, 22.0 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 10.0 55.2576644707 119.8305915233 -99.8305915233
A/J m 8.0 55.2576644707 117.8305915233 -101.8305915233
BALB/cByJ f 22.5 55.2576644707 132.3305915233 -87.3305915233
BALB/cByJ m 6.3333333333 45.1176941104 96.0096357934 -83.3429691267
BALB/cJ f 205.5 55.2576644707 315.3305915233 95.6694084767
BALB/cJ m 24.6666666667 45.1176941104 114.3429691267 -65.0096357934
BPL/1J f 81.6666666667 45.1176941104 171.3429691267 -8.0096357934
BPL/1J m 36.0 45.1176941104 125.67630246 -53.67630246
BTBR T+ Itpr3tf/J f 1.6666666667 45.1176941104 91.3429691267 -88.0096357934
BTBR T+ Itpr3tf/J m 1.0 55.2576644707 110.8305915233 -108.8305915233
BXD2/TyJ f 28.3333333333 45.1176941104 118.0096357934 -61.3429691267
BXD2/TyJ m 198.6666666667 45.1176941104 288.3429691267 108.9903642066
BXD31/TyJ f 2.5 55.2576644707 112.3305915233 -107.3305915233
BXD31/TyJ m 5.0 39.0730692598 82.6619560478 -72.6619560478
BXD38/TyJ f 11.3333333333 45.1176941104 101.0096357934 -78.3429691267
BXD38/TyJ m 167.0 55.2576644707 276.8305915233 57.1694084767
BXD48a/RwwJ f 3.5 55.2576644707 113.3305915233 -106.3305915233
BXD48a/RwwJ m 17.3333333333 45.1176941104 107.0096357934 -72.3429691267
BXD65/RwwJ f 11.3333333333 45.1176941104 101.0096357934 -78.3429691267
BXD65/RwwJ m 7.0 45.1176941104 96.67630246 -82.67630246
BXD77/RwwJ f 3.3333333333 45.1176941104 93.0096357934 -86.3429691267
BXD77/RwwJ m 7.3333333333 45.1176941104 97.0096357934 -82.3429691267
BXD98/RwwJ f 5.5 55.2576644707 115.3305915233 -104.3305915233
BXD98/RwwJ m 3.3333333333 45.1176941104 93.0096357934 -86.3429691267
C3HeB/FeJ f 6.0 45.1176941104 95.67630246 -83.67630246
C3HeB/FeJ m 3.5 55.2576644707 113.3305915233 -106.3305915233
C57BL/10J f 5.0 45.1176941104 94.67630246 -84.67630246
C57BL/10J m 1.5 55.2576644707 111.3305915233 -108.3305915233
C57BLKS/J f 1.5 55.2576644707 111.3305915233 -108.3305915233
C57BLKS/J m 3.6666666667 45.1176941104 93.3429691267 -86.0096357934
C57BR/cdJ f 14.0 45.1176941104 103.67630246 -75.67630246
C57BR/cdJ m 2.0 55.2576644707 111.8305915233 -107.8305915233
C58/J f 14.3333333333 45.1176941104 104.0096357934 -75.3429691267
C58/J m 7.3333333333 45.1176941104 97.0096357934 -82.3429691267
CBA/J f 4.3333333333 45.1176941104 94.0096357934 -85.3429691267
CBA/J m 1.0 45.1176941104 90.67630246 -88.67630246
DBA/1J f 2.5 55.2576644707 112.3305915233 -107.3305915233
DBA/1J m 1.6666666667 45.1176941104 91.3429691267 -88.0096357934
FVB/NJ f 5.3333333333 45.1176941104 95.0096357934 -84.3429691267
FVB/NJ m 7.5 55.2576644707 117.3305915233 -102.3305915233
KK/HlJ f 1.3333333333 45.1176941104 91.0096357934 -88.3429691267
KK/HlJ m 9.5 55.2576644707 119.3305915233 -100.3305915233
MRL/MpJ f 18.3333333333 45.1176941104 108.0096357934 -71.3429691267
MRL/MpJ m 3.0 55.2576644707 112.8305915233 -106.8305915233
NOD/ShiLtJ f 38.0 45.1176941104 127.67630246 -51.67630246
NOD/ShiLtJ m 25.0 45.1176941104 114.67630246 -64.67630246
NZO/HlLtJ f 4.0 55.2576644707 113.8305915233 -105.8305915233
NZO/HlLtJ m 164.6666666667 45.1176941104 254.3429691267 74.9903642066
NZW/LacJ f 2.5 55.2576644707 112.3305915233 -107.3305915233
NZW/LacJ m 28.5 55.2576644707 138.3305915233 -81.3305915233
SM/J f 7.25 39.0730692598 84.9119560478 -70.4119560478
SM/J m 7.0 39.0730692598 84.6619560478 -70.6619560478


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 9.0 39.0730692598 86.6619560478 -68.6619560478
BALB/cByJ both 14.4166666667 35.6686690409 85.3120086456 -56.4786753123
BALB/cJ both 115.0833333333 35.6686690409 185.9786753123 44.1879913544
BPL/1J both 58.8333333333 31.903027457 122.2440549145 -4.5773882479
BTBR T+ Itpr3tf/J both 1.3333333333 35.6686690409 72.2286753123 -69.5620086456
BXD2/TyJ both 113.5 31.903027457 176.9107215812 50.0892784188
BXD31/TyJ both 3.75 33.8382705828 71.007226845 -63.507226845
BXD38/TyJ both 89.1666666667 35.6686690409 160.0620086456 18.2713246877
BXD48a/RwwJ both 10.4166666667 35.6686690409 81.3120086456 -60.4786753123
BXD65/RwwJ both 9.1666666667 31.903027457 72.5773882479 -54.2440549146
BXD77/RwwJ both 5.3333333333 31.903027457 68.7440549146 -58.0773882479
BXD98/RwwJ both 4.4166666667 35.6686690409 75.3120086456 -66.4786753123
C3HeB/FeJ both 4.75 35.6686690409 75.645341979 -66.145341979
C57BL/10J both 3.25 35.6686690409 74.145341979 -67.645341979
C57BLKS/J both 2.5833333333 35.6686690409 73.4786753123 -68.3120086456
C57BR/cdJ both 8.0 35.6686690409 78.895341979 -62.895341979
C58/J both 10.8333333333 31.903027457 74.2440549146 -52.5773882479
CBA/J both 2.6666666667 31.903027457 66.0773882479 -60.7440549146
DBA/1J both 2.0833333333 35.6686690409 72.9786753123 -68.8120086456
FVB/NJ both 6.4166666667 35.6686690409 77.3120086456 -64.4786753123
KK/HlJ both 5.4166666667 35.6686690409 76.3120086456 -65.4786753123
MRL/MpJ both 10.6666666667 35.6686690409 81.5620086456 -60.2286753123
NOD/ShiLtJ both 31.5 31.903027457 94.9107215812 -31.9107215812
NZO/HlLtJ both 84.3333333333 35.6686690409 155.2286753123 13.4379913544
NZW/LacJ both 15.5 39.0730692598 93.1619560478 -62.1619560478
SM/J both 7.125 27.6288322354 62.0402957616 -47.7902957616




  GWAS USING LINEAR MIXED MODELS