MPD: Phenotype measures mapped to MP:0002127, abnormal cardiovascular system morphology

Phenotype measures associated with ontology term
MP:0002127 'abnormal cardiovascular system morphology'

All measures in this list are mapped to the ontology descendants of MP:0002127. None are mapped to MP:0002127 directly.

MP:0003921 abnormal heart left ventricle morphology
MP:0004857 abnormal heart weight
MP:0005338 atherosclerotic lesions
MP:0005340 altered susceptibility to atherosclerosis
MP:0010482 abnormal aortic sinus morphology
MP:0012687 abnormal heart atrium weight
MP:0012688 abnormal heart ventricles weight
MP:0020135 abnormal heart ventricle wall thickness
MP:0020136 abnormal interventricular septum thickness
MP:0020204 abnormal heart left ventricle weight
MP:0020205 abnormal heart right ventricle weight
MP:0020207 abnormal heart right atrium weight

This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Ankra-Badu1:11	Ankra-Badu1	organ weights	(none)	heart weight [mg] HEART 21211	QTL population		both	10wks	N=502	2009

Attie2:136	Attie2	organ weights	high-fat high-sucrose diet	heart weight after diet [g] heart_wt 110753	DO population		both	19-26wks	N=194	2018

Auwerx1:223	Auwerx1	organ weights	high-fat diet	heart weight [g] heart_wt 111402 CD HFD	BXD w/par	56	m	29wks	N=4	2016

Auwerx2:127	Auwerx2	organ weights	(none)	heart weight [g] heart_wt 114655 CD HFD	inbred w/CC8	9	both	21wks	N=4	2021

Auwerx2:129	Auwerx2	organ weights	(none)	heart atria weight [g] heart_atria_wt 114657 CD HFD	inbred w/CC8	9	both	21wks	N=4	2021

Chesler2:63	Chesler2	organ weights	(none)	heart weight [g] heart_wt 43492	CC diallel w/par	46	both	7-15wks	N=3	2011

Chesler3:92	Chesler3	organ weights	(none)	heart weight [g] heart_wt 43592	CC pre w/par	352	both	7-15wks	N=2	2011

Cheverud1:19	Cheverud1	organ weights	high-fat diet	heart weight as percentage of body weight [%] heartwt_adj 17821 control diet high-fat diet	LGXSM w/par	17	both	20-30wks	N=8	2004

Deschepper1:3	Deschepper1	organ weights	(none)	ventricle weight [mg] heart_V 10403 right left both	inbred	13	both	10wks	N=10	2004

Deschepper1:4	Deschepper1	organ weights	(none)	ventricle weight, normalized to body weight [mg] heart_V_adj 10404 right left both	inbred	13	both	10wks	N=10	2004

Deschepper1:9	Deschepper1	organ weights	(none)	atria weight [mg] heart_A 10409 right left both	inbred	13	both	10wks	N=10	2004

Deschepper1:10	Deschepper1	organ weights	(none)	atria weight, normalized to body weight [mg] heart_A_adj 10410 right left both	inbred	13	both	10wks	N=10	2004

DiPetrillo3:3	DiPetrillo3	organ weights	(none)	heart weight [g] HeartWt 13903	QTL population		both	8wks	N=108	2004

Eumorphia6:1	Eumorphia6	organ weights	(none)	left ventricle weight [mg] heart_LV 29501 weight normalized to bw	inbred	4	both	12wks	N=6	2008

Eumorphia6:3	Eumorphia6	echocardiography	(none)	interventricular septum thickness [mm] septum_thickness 29503	inbred	4	both	12wks	N=6	2008

Eumorphia6:4	Eumorphia6	echocardiography	(none)	right ventricle wall thickness [mm] heart_RV 29504	inbred	4	both	12wks	N=6	2008

Eumorphia6:5	Eumorphia6	echocardiography	(none)	left ventricle end-diastolic diameter [mm] LVEDD 29505	inbred	4	both	12wks	N=6	2008

Eumorphia6:6	Eumorphia6	echocardiography	(none)	left ventricle end-systolic diameter [mm] LVESD 29506	inbred	4	both	12wks	N=6	2008

Eumorphia6:7	Eumorphia6	echocardiography	(none)	cardiac fractional shortening [%] shortening_fraction 29507	inbred	4	both	12wks	N=6	2008

Eumorphia6:9	Eumorphia6	echocardiography	(none)	cardiac aorta diameter [mm] aortic_diameter 29509	inbred	4	both	12wks	N=6	2008

Eumorphia6:10	Eumorphia6	echocardiography	(none)	cardiac aorta volume change [cm] aortic_dV_dt 29510	inbred	4	both	12wks	N=6	2008

GMC12:21	GMC12	echocardiography	(none)	left ventricular mass corrected [mg] LV_mass 56121	inbred w/CC8	8	both	14-15wks	N=17	2018

GMC12:22	GMC12	echocardiography	(none)	fractional shortening [%] fract_shortening 56122	inbred w/CC8	8	both	14-15wks	N=17	2018

GMC12:23	GMC12	echocardiography	(none)	ejection fraction [%] EJ_fraction 56123	inbred w/CC8	8	both	14-15wks	N=17	2018

GMC12:24	GMC12	echocardiography	(none)	stroke volume, volume of blood pumped from one ventricle of the heart with each beat [µL] stroke_vol 56124	inbred w/CC8	8	both	14-15wks	N=17	2018

GMC12:25	GMC12	echocardiography	(none)	cardiac output, volume of blood pumped by the heart per min [mL/min] cardiac_output 56125	inbred w/CC8	8	both	14-15wks	N=13	2018

GMC12:31	GMC12	echocardiography	(none)	interventricular septum [mm] IVS 56131 diastole systole	inbred w/CC8	8	both	14-15wks	N=17	2018

GMC12:33	GMC12	echocardiography	(none)	left ventricular internal dimension [mm] LVID 56133 diastole systole	inbred w/CC8	8	both	14-15wks	N=17	2018

GMC12:35	GMC12	echocardiography	(none)	left ventricular posterior wall width [mm] LVPW 56135 diastole systole	inbred w/CC8	8	both	14-15wks	N=17	2018

GMC21:3	GMC21	organ weights	(none)	heart weight [mg] heart_wt 57003	inbred w/CC8	8	both	21wks	N=11	2018

HMDPpheno11:1	HMDPpheno11	histopathology	high-fat high-cholesterol diet	aortic lesion size (area) [µm²] aortic_lesion 110077	HMDP hAPOE and hCETP transgenic	103	both	23-25wks	N=5	2015

Ishimori1:9	Ishimori1	histopathology	high-fat diet	fatty streak aortic lesions (0=absent, 1=present) [score] aortic_lesion_presence 14009	QTL population		f	20wks	N=294	2004

Ishimori1:10	Ishimori1	histopathology	high-fat diet	fatty streak aortic lesion size [µm²] aortic_lesion 14010	QTL population		f	20wks	N=294	2004

Ishimori1:11	Ishimori1	histopathology	high-fat diet	fatty streak aortic lesion size, log transformed [log(µm²)] aortic_lesion_log 14011	QTL population		f	20wks	N=294	2004

JaxCC1:9237	JaxCC1	organ weights	(none)	heart weight [mg] heart_wt 89237 weight normalized to body weight	CC	18	both	17-19wks	N=6	2017

JaxKOMP-EAP:421	JaxKOMP-EAP	organ weights	(none)	heart weight [mg] heart_wt heart_weight 100583 weight normalized to body weight	KOMP	1854	both	18wks	N=8	2021

JaxKOMP-LAP:334	JaxKOMP-LAP	organ weights	(none)	heart weight [mg] heart_wt heart_weight 101583 weight normalized to body weight	KOMP	115	both	75-81wks	N=8	2021

Jaxpheno2:10	Jaxpheno2	organ weights	(none)	heart weight [g] heart 22710 age 8wks age 16wks	inbred	11	both		N=8	2006

Jaxpheno2:12	Jaxpheno2	organ weights	(none)	heart weight as percentage of body weight [%] pct_heart 22712 age 8wks age 16wks	inbred	11	both		N=8	2006

Jaxpheno8:17	Jaxpheno8	echocardiography	(none)	interventricular septum thickness [mm] IVS 35017 diastolic systolic	inbred	6	m	12wks	N=5	2010

Jaxpheno8:19	Jaxpheno8	echocardiography	(none)	left ventricle anterior wall thickness [mm] LV_AW 35019 diastolic systolic	inbred	6	m	12wks	N=5	2010

Jaxpheno8:21	Jaxpheno8	echocardiography	(none)	left ventricle posterior wall thickness [mm] LV_PW 35021 diastolic systolic	inbred	6	m	12wks	N=5	2010

Jaxpheno8:23	Jaxpheno8	echocardiography	(none)	left ventricle internal dimension [mm] LVID 35023 diastolic systolic	inbred	6	m	12wks	N=5	2010

Jaxpheno8:25	Jaxpheno8	echocardiography	(none)	left ventricle volume [µL] LV_vol 35025 diastolic systolic	inbred	6	m	12wks	N=5	2010

Jaxpheno8:32	Jaxpheno8	echocardiography	(none)	left ventricle fractional shortening [%] LV_pctFS 35032	inbred	6	m	12wks	N=5	2010

Li1:8	Li1	histopathology	western diet	carotid atherosclerotic lesion area size (the average of 5 largest sections) [µm²/section] Carotid_lesion-LGMax 21008	QTL population		f	12wks	N=241	2008

Lionikas1:9	Lionikas1	organ weights	exercise	weight of cardiac ventricles [g] ventricles 48509 control exercise	inbred	6	m	11-14wks	N=15	2012

Maeda1:1	Maeda1	histopathology	(none)	aortic lesion size at root, square root transformed [µm²] Sqrt_Root 60301	QTL population		both	18-20wks	N=116	2017

Maeda1:2	Maeda1	histopathology	(none)	lesion size at aortic arch, square root transformed [µm²] Sqr_Area1 60302	QTL population		both	18-20wks	N=116	2017

Maeda1:3	Maeda1	histopathology	(none)	lesion size at innominate artery, square root transformed [µm²] Sqr_Area2 60303	QTL population		both	18-20wks	N=116	2017

Maeda1:4	Maeda1	histopathology	(none)	lesion size at left common carotid artery, square root transformed [µm²] Sqr_Area3 60304	QTL population		both	18-20wks	N=116	2017

Maeda1:5	Maeda1	histopathology	(none)	lesion size at subclavian artery plus upper wall, square root transformed [µm²] Sqr_Area4 60305	QTL population		both	18-20wks	N=116	2017

Maurer1:70	Maurer1	organ weights	atenolol, isoproterenol	heart weight [mg] heart_wt 33270 control atenolol 10mg isoprot 1mg isoprot 10mg	inbred	23	m	7-13wks	N=11	2009

Maurer1:74	Maurer1	organ weights	atenolol, isoproterenol	heart weight normalized to body weight [mg/g] heart_adjwt 33274 control atenolol 10mg isoprot 1mg isoprot 10mg	inbred	23	m	7-13wks	N=11	2009

Maurer1:78	Maurer1	organ weights	atenolol, isoproterenol	atria weight [mg] atria_wt 33278 control atenolol 10mg isoprot 1mg isoprot 10mg	inbred	23	m	7-13wks	N=10	2009

Maurer1:82	Maurer1	organ weights	atenolol, isoproterenol	atria weight normalized to body weight [mg/g] atria_adjwt 33282 control atenolol 10mg isoprot 1mg isoprot 10mg	inbred	23	m	7-13wks	N=10	2009

Maurer1:86	Maurer1	organ weights	atenolol, isoproterenol	ventricle (both) weight [mg] ventr_wt 33286 control atenolol 10mg isoprot 1mg isoprot 10mg	inbred	23	m	7-13wks	N=11	2009

Maurer1:90	Maurer1	organ weights	atenolol, isoproterenol	ventricle (both) weight normalized to body weight [mg/g] ventr_adjwt 33290 control atenolol 10mg isoprot 1mg isoprot 10mg	inbred	23	m	7-13wks	N=11	2009

Maurer1:94	Maurer1	organ weights	atenolol, isoproterenol	atria weight to ventricle weight ratio [ratio] atr_ventr 33294 control atenolol 10mg isoprot 1mg isoprot 10mg	inbred	23	m	7-13wks	N=10	2009

Paigen1:36	Paigen1	histopathology	high-fat diet	fatty streak aortic lesion size [µm²] aortic_lesion 2936	inbred	44	both	15-19wks	N=8	2000

Paigen2:24	Paigen2	histopathology	high-fat diet	fatty streak aortic lesion size [µm²] aortic_lesion 9924	inbred w/CC7	42	both	25-27wks	N=9	2002

Paigen3:36	Paigen3	histopathology	high-fat diet	fatty streak aortic lesion size [µm²] aortic_lesion 2836	obesity mutants	7	both	15-19wks	N=8	2000

Reed1:1	Reed1	organ weights	(none)	heart weight [g] heart 32601 weight [g] as percent of body weight [%]	inbred	28	m	29-67wks	N=12	2009

Reed2:36	Reed2	organ weights	(none)	heart weight [g] heart_wt 53136	B6.129 and 129.B6 consomic w/par	9	both	26wks	N=17	2015

Su2:6	Su2	histopathology	high-fat diet	aortic lesion size Lesion 24506	QTL population		f	14wks	N=277	2009

Su2:7	Su2	histopathology	high-fat diet	aortic lesion size, log transformed LogLesion 24507	QTL population		f	14wks	N=277	2009

Sugiyama3:11	Sugiyama3	organ weights	(none)	heart weight after testing [mg] heart_wt 12511	QTL population		m	10wks	N=208	2002

Sugiyama3:12	Sugiyama3	organ weights	(none)	heart weight after testing, log transformed [log(mg)] heart_wt_log 12512	QTL population		m	10wks	N=208	2002

Wang1:27	Wang1	histopathology	high-fat diet	fatty streak aortic lesion size [µm²] aortic_lesion 13717	QTL population		f	23wks	N=100	2003

Zhang1:3	Zhang1	histopathology	western diet	maximal carotid lesion [µm²] Carotid_lesion_max 27903	QTL population		f	18wks	N=266	2012

Zhang1:4	Zhang1	histopathology	western diet	maximal lesion, ln transformed Carotid_lesion_LnMax 27904	QTL population		f	18wks	N=266	2012

Zhang1:5	Zhang1	histopathology	western diet	maximal lesion, log transformed Carotid_lesion_L10Max 27905	QTL population		f	18wks	N=266	2012

Zhang1:6	Zhang1	histopathology	western diet	maximal lesion, square root Carotid_lesion_MasSQ 27906	QTL population		f	18wks	N=266	2012

Zhang1:7	Zhang1	histopathology	western diet	average maximal 5 lesion [µm²/section] Carotid_lesion_Amax5 27907	QTL population		f	18wks	N=266	2012

Zhang1:8	Zhang1	histopathology	western diet	average maximal 5 lesion, ln transformed Carotid_lesion_LnAmax5 27908	QTL population		f	18wks	N=266	2012

Zhang1:9	Zhang1	histopathology	western diet	average maximal 5 lesion, log transformed Carotid_lesion_L10Am5 27909	QTL population		f	18wks	N=266	2012

Zhang1:10	Zhang1	histopathology	western diet	average maximal 5 lesion, square root Carotid_lesion_Am5sq 27910	QTL population		f	18wks	N=266	2012

Zhang1:11	Zhang1	histopathology	western diet	average lesion [µm²/section] Carotid_lesion_average 27911	QTL population		f	18wks	N=266	2012

Zhang1:12	Zhang1	histopathology	western diet	average lesion, ln transformed Carotid_lesion_LnAvg 27912	QTL population		f	18wks	N=266	2012

Zhang1:13	Zhang1	histopathology	western diet	average lesion, log transformed Carotid_lesion_L10Avg 27913	QTL population		f	18wks	N=266	2012

Zhang1:14	Zhang1	histopathology	western diet	average lesion, square root Carotid_lesion_AvgSq 27914	QTL population		f	18wks	N=266	2012

Zhang1:15	Zhang1	histopathology	western diet	lesion double-checked [µm²/section] Carotid_lesion-recheck 27915	QTL population		f	18wks	N=266	2012

Zhang1:16	Zhang1	histopathology	western diet	maximal lesion [µm²] Aortic_lesion_Max 27916	QTL population		f	18wks	N=266	2012

Zhang1:17	Zhang1	histopathology	western diet	average lesion [µm²/section] Aortic_lesion_Aveg 27917	QTL population		f	18wks	N=266	2012

Zhang1:18	Zhang1	histopathology	western diet	average maximal 5 lesion [µm²/section] Aortic_lesion_Amax5 27918	QTL population		f	18wks	N=266	2012

Zhang1:19	Zhang1	histopathology	western diet	average maximal 5 lesion, ln transformed Aortic_lesion_LnAmax5 27919	QTL population		f	18wks	N=266	2012

Zhang1:20	Zhang1	histopathology	western diet	maximal lesion, square root Aortic_lesion_Max_Sqrt 27920	QTL population		f	18wks	N=266	2012

Zhang1:21	Zhang1	histopathology	western diet	average lesion, square root Aortic_lesion_Avg_sqrt 27921	QTL population		f	18wks	N=266	2012

Zhang1:22	Zhang1	histopathology	western diet	average maximal 5 lesion, square root Aortic_lesion_Amax5_sqrt 27922	QTL population		f	18wks	N=266	2012

Zhang1:23	Zhang1	histopathology	western diet	maximal lesion, ln transformed Aortic_lesion_Max_LN 27923	QTL population		f	18wks	N=266	2012

Zhang1:24	Zhang1	histopathology	western diet	average lesion, ln transformed Aortic_lesion_Avg_LN 27924	QTL population		f	18wks	N=266	2012

Zhang1:26	Zhang1	histopathology	western diet	maximal 10 lesion [µm²/section] Aortic_lesion_Max10 27926	QTL population		f	18wks	N=266	2012

Zhang1:27	Zhang1	histopathology	western diet	average lesion, log10 transformed Aortic_lesion_Aveg_log10 27927	QTL population		f	18wks	N=266	2012

Zhang1:46	Zhang1	histopathology	western diet	total aortic lesion size [µm²] Aortic_lesion_Sum 27946	QTL population		f	18wks	N=266	2012

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