Paigen2: Diet effects on plasma lipids and susceptibility to atherosclerosis in 43 inbred strains of mice on high-fat atherogenic diet (under pathogen-free conditions) (2002)
Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL. Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations.
J Appl Physiol. 2007 Jun;102(6):2369-78. Epub 2007 Feb 22.
Paigen2 downloads
• Download Paigen2 project data set animal data, as uploaded
• Download Paigen2 animal data matrix with factor-related expansion applied as necessary
• Download Paigen2 strain means, SD, N, etc. one row per strain/sex/measure
• Download Paigen2 project data set animal data, as uploaded
• Download Paigen2 animal data matrix with factor-related expansion applied as necessary
• Download Paigen2 strain means, SD, N, etc. one row per strain/sex/measure
Ontology terms mapped to Paigen2 measures:
| Investigators |
Beverly Paigen The Jackson Laboratory, Bar Harbor, ME Karen L Svenson The Jackson Laboratory, Bar Harbor, ME Luanne L Peters The Jackson Laboratory, Bar Harbor, ME |
| Participants | Von Smith R |
| Contact | Beverly Paigen bev.paigen@jax.org |
| Affiliated Center | JAX Heart, Lung, and Blood Center (HLB) |
| Acknowledgements | Funding provided by NIH HL66611
In fulfillment of NIH requirements that all information is made promptly and freely available to the research community, data are deposited in the MPD when complete. |
| Phenotype strain survey data set | |
| MPD identifiers | Paigen2 MPD:99 |
| 4 updates/corrections. Initial release date: 05/2003. | |
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Click above to copy-paste the entire citation for this MPD web page. |
Animals were evaluated at baseline and then again after 17 wks on
high fat (15% fat) diet.
Procedures conducted:
Procedures conducted:
| Aortic lesion size histopathology. Baseline vs. high-fat diet (17wks). | ||
| Cholesterol, HDL, non-HDL, triglycerides. Baseline vs. high-fat diet (17wks). 4h fast, plasma. |
