Williams EG, Wu Y, Jha P, Dubuis S, Blattmann P, Argmann CA, Houten SM, Amariuta T, Wolski W, Zamboni N, Aebersold R, Auwerx J. Systems proteomics of liver mitochondria function.
Science. 2016 Jun 10;352(6291):aad0189. doi: 10.1126/science.aad0189.
Jha P, McDevitt MT, Halilbasic E, Williams EG, Quiros PM, Gariani K, Sleiman MB, Gupta R, Ulbrich A, Jochem A, Coon JJ, Trauner M, Pagliarini DJ, Auwerx J. Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes.
Cell Syst. 2018 Jun 27;6(6):709-721.e6. doi: 10.1016/j.cels.2018.05.009. Epub 2018 Jun 13.
Investigators |
Evan G Williams Ecole polytechnique fédérale de Lausanne, Lausanne SWITZERLAND Yibo Wu Institute of Molecular Systems Biology, Zurich SWITZERLAND Ruedi Aebersold Institute of Molecular Systems Biology, Zurich SWITZERLAND Johan Auwerx Ecole polytechnique fédérale de Lausanne, Lausanne SWITZERLAND |
Participants | Bou Sleiman M, Rapin A, Jha P, Dubuis S, Blattmann P, Argmann CA, Houten SM, Amariuta T, Wolski W, Zamboni N |
Contact | Johan Auwerx johan.auwerx@epfl.ch
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Funding Provided By | NIH AG043930; EPFL, ETHZ, ERC (AdG-670821 and Proteomics v3.0; AdG-233226), the AgingX program of the Swiss Initiative for Systems Biology (51RTP0-151019, 2013/134, and 2013/153), SNSF (31003A-140780, 31003A-143914, and CSRII3-13620 |
Phenotype strain survey data set | |
MPD identifiers | Auwerx1 MPD:1023 |
No updates/corrections. Initial release date: 11/2020. | |
Click above to copy-paste the entire citation for this MPD web page. |
8-29 wks of age. | ||
Body composition. | ||
Food intake. | ||
Oxygen consumption and respiratory exchange ratio (RER); activity. | ||
Glucose post oral gavage: 0, 15, 30, 45, 60, 90, 120, 150, 180 min plus area under curve. | ||
Glucose post oral gavage: 0, 15, 30 min plus area under curve. | ||
Blood pressure and heart rate. | ||
In cold room: 0, 1, 2, 3, 4, 5, 6 h. | ||
Distance traveled. | ||
Distance traveled, speed. | ||
Enzymes, bile acid, proteins, creatinine, glucose, iron, lactate. | ||
Cholesterol, HDL, LDL, free fatty acids, triglyceride. | ||
INF-gamma, interleukins, monocyte chemoattractant, macrophage inflammatory protein, T cell RANTES, TNF-alpha. | ||
RBC, hematocrit. | ||
Skeletal muscle, soleus muscle, heart, kidney, liver, various fat pads. |