MPD: Project measures / variables set: Maurer1 ventr

Project measures / variables set: Maurer1 ventr_adjwt

ID, description, units	MPD:33290 ventr_adjwt ventricle (both) weight normalized to body weight [mg/g] atenolol, isoproterenol study
Measures	• control • atenolol 10mg • isoprot 1mg • isoprot 10mg
Data set, strains	Maurer1 inbred 23 strains sex: m age: 7-13wks
Procedure	organ weights
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0005294 heart ventricle morphology trait VT:0010298 heart ventricle size trait VT:0010487 response to xenobiotic stimulus trait MA:0000091 heart ventricle MP:0008872 abnormal physiological response to xenobiotic MP:0012688 abnormal heart ventricles weight

Values Means Δ Means Z-scores

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Maurer1 - ventricle (both) weight normalized to body weight

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	3	75.2749	25.0916	276.4764	< 0.0001
strain	22	177.1706	8.0532	88.7356	< 0.0001
group:strain	66	19.8833	0.3013	3.3195	< 0.0001
Residuals	873	79.2292	0.0908

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Maurer1	33290	organ weights	atenolol, isoproterenol	ventricle (both) weight normalized to body weight [mg/g] control ventr_adjwt_ctrl	inbred	23	m	7-13wks
Maurer1	33291	organ weights	atenolol, isoproterenol	ventricle (both) weight normalized to body weight [mg/g] atenolol 10mg ventr_adjwt_at	inbred	23	m	7-13wks
Maurer1	33292	organ weights	atenolol, isoproterenol	ventricle (both) weight normalized to body weight [mg/g] isoprot 1mg ventr_adjwt_iso1	inbred	23	m	7-13wks
Maurer1	33293	organ weights	atenolol, isoproterenol	ventricle (both) weight normalized to body weight [mg/g] isoprot 10mg ventr_adjwt_iso10	inbred	23	m	7-13wks