MPD: Phenotype measures mapped to MP:0005418, abnormal circulating hormone level

Phenotype measures associated with ontology term
MP:0005418 'abnormal circulating hormone level'

All measures in this list are mapped to the ontology descendants of MP:0005418. None are mapped to MP:0005418 directly.

MP:0001560 abnormal circulating insulin level
MP:0002903 abnormal circulating parathyroid hormone level
MP:0004700 abnormal circulating insulin-like growth factor I level
MP:0005345 abnormal circulating corticosterone level
MP:0005475 abnormal circulating thyroxine level
MP:0005667 abnormal circulating leptin level
MP:0011611 abnormal circulating ghrelin level
MP:0011922 abnormal circulating osteocalcin level

This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Attie2:80	Attie2	hormone quantification	high-fat high-sucrose diet	plasma insulin after diet (4h fast) [ng/mL] INS 110697 wk: 6 10 14 22	DO population		both	10-26wks	N=250	2018

Attie2:90	Attie2	glucose tolerance	high-fat high-sucrose diet	insulin level at t=0 after ~14 wks on diet (4h fast) [ng/mL] INS_0min 110707	DO population		both	18wks	N=248	2018

Attie2:91	Attie2	glucose tolerance	high-fat high-sucrose diet	HOMA-IR: (glucose x insulin) / 405 at t=0 after ~14 wks on diet (4h fast) HOMA_IR 110708	DO population		both	18wks	N=248	2018

Attie2:92	Attie2	glucose tolerance	high-fat high-sucrose diet	HOMA-B: (360 x insulin) / (glucose minus 63) at t=0 after ~14 wks on diet (4h fast) HOMA_B 110709	DO population		both	18wks	N=246	2018

Attie2:96	Attie2	glucose tolerance	high-fat high-sucrose diet	insulin area under curve (AUC) after ~14 wks on diet after subtraction of insulin at t=0 (4h fast) [AUC] INS_AUC_adj 110713	DO population		both	18wks	N=248	2018

Attie2:98	Attie2	hormone quantification	high-fat high-sucrose diet	plasma leptin measured at the time oral glucose tolerance test performed after ~14 wks on diet (4h fast) [ng/mL] leptin 110715	DO population		both	18wks	N=96	2018

Auwerx1:85	Auwerx1	hormone quantification	high-fat diet	insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 111264 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:87	Auwerx1	hormone quantification	high-fat diet	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 111266 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:89	Auwerx1	hormone quantification	high-fat diet	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 111268 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:91	Auwerx1	hormone quantification	high-fat diet	insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) [AUC] ogtt_ins_auc 111270 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx2:73	Auwerx2	hormone quantification	(none)	insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 114601 CD HFD	inbred w/CC8	9	both	16wks	N=4	2021

Auwerx2:75	Auwerx2	hormone quantification	(none)	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 114603 CD HFD	inbred w/CC8	8	both	16wks	N=4	2021

Auwerx2:77	Auwerx2	hormone quantification	(none)	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 114605 CD HFD	inbred w/CC8	8	both	16wks	N=4	2021

Beamer2:2	Beamer2	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1), normalized [ng/mL] IGF1_adj 11202	QTL population		f	16wks	N=999	2001

Bennett4:93	Bennett4	hormone quantification	various diets 2	plasma insulin amount, baseline [ng/mL] INS_base 114787 diet: HP group HFHS group	CC	22	f	8-11wks	N=5	2021

Bennett4:95	Bennett4	hormone quantification	various diets 2	plasma insulin amount, post-diet [ng/mL] INS_post 114789 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Bennett4:97	Bennett4	hormone quantification	various diets 2	plasma glucose to insulin ratio, baseline [ratio] GLU_INS_base 114791 diet: HP group HFHS group	CC	22	f	8-11wks	N=5	2021

Bennett4:99	Bennett4	hormone quantification	various diets 2	plasma glucose to insulin ratio, post-diet [ratio] GLU_INS_post 114793 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Brockmann1:29	Brockmann1	hormone quantification	(none)	leptin level [ng/mL] leptin 21509	QTL population		both	6wks	N=201	2009

Brockmann1:30	Brockmann1	hormone quantification	(none)	insulin level [pmol/L] insulin 21510	QTL population		both	6wks	N=201	2009

Brockmann1:31	Brockmann1	hormone quantification	(none)	IGF-1 level [ng/mL] igf1 21511	QTL population		both	6wks	N=201	2009

Brockmann1:32	Brockmann1	hormone quantification	(none)	leptin level, log10 transformed [log(ng/mL)] lg_lept 21512	QTL population		both	6wks	N=201	2009

Brockmann1:33	Brockmann1	hormone quantification	(none)	insulin level, log10 transformed [log(pmol/L)] lg_ins 21513	QTL population		both	6wks	N=201	2009

Brockmann1:34	Brockmann1	hormone quantification	(none)	IGF1 level, log10 transformed [log(ng/mL)] lg_igf1 21514	QTL population		both	6wks	N=201	2009

CGDpheno1:70	CGDpheno1	metabolic panel	(none)	thyroxine (plasma T4) [µg/dL] T4 31870	inbred w/CC8	72	both	12wks	N=7	2009

Cheverud1:45	Cheverud1	hormone quantification	high-fat diet	insulin (serum) [ng/mL] insulin 17840 control diet high-fat diet	LGXSM w/par	17	both	20-30wks	N=8	2004

Cheverud1:47	Cheverud1	hormone quantification	high-fat diet	leptin (serum) [pg/mL] leptin 17841 control diet high-fat diet	LGXSM w/par	10	both	20-30wks	N=6	2004

Donahue1:16	Donahue1	hormone quantification	(none)	osteocalcin (serum OC) [ng/mL] osteocalcin 11530	inbred w/CC7	30	both	15-16wks	N=9	2002

Donahue1:17	Donahue1	metabolic panel	(none)	thyroxine (serum T4) [µg/dL] thyroxine 11531	inbred w/CC7	29	both	15-16wks	N=9	2002

Donahue1:18	Donahue1	hormone quantification	(none)	insulin-like growth factor 1 (adjusted serum IGF-1) [ng/mL] IGF_1 11532	inbred w/CC7	30	both	15-16wks	N=9	2002

Ishimori1:17	Ishimori1	hormone quantification	high-fat diet	parathyroid hormone [pg/mL] PTH 14017	QTL population		f	20wks	N=294	2004

Ishimori1:18	Ishimori1	hormone quantification	high-fat diet	parathyroid hormone, log transformed [log(pg/mL)] PTH_log 14018	QTL population		f	20wks	N=294	2004

JaxCC1:9201	JaxCC1	hormone quantification	(none)	insulin (plasma) [pg/mL] insulin 89201	CC	18	both	17-19wks	N=6	2017

JaxKOMP-EAP:445	JaxKOMP-EAP	hormone quantification	(none)	insulin (plasma) [pg/mL] insulin 100637	KOMP	410	both	18wks	N=14	2016

Jaxpheno3:20	Jaxpheno3	metabolic panel	(none)	thyroxine (plasma T4) [µg/dL] T4 22820 age 8wks age 16wks	inbred	11	both		N=16	2006

Kim1:3	Kim1	hormone quantification	(none)	non-fasted insulin level [ng/mL] Insulin 11403	QTL population		m	26wks	N=206	2001

Leiter2:16	Leiter2	hormone quantification	(none)	leptin in plasma [ng/mL] Leptin 24016	QTL population		f	14-40wks	N=310	2009

Leiter2:17	Leiter2	hormone quantification	(none)	insulin in plasma [ng/mL] Insulin 24017	QTL population		f	14-40wks	N=310	2009

Nadeau2:7	Nadeau2	hormone quantification	high-fat high-sucrose diet	insulin (plasma, 16h fast) [pmol/L] INS 53022	B6.A consomic w/par	24	m	21wks	N=39	2015

Nadeau2:8	Nadeau2	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (HOMA-IR, 16h fast) HOMA_IR 53023	B6.A consomic w/par	24	m	21wks	N=39	2015

Nadeau3:7	Nadeau3	hormone quantification	high-fat high-sucrose diet	insulin amount (overnight fast) after 16 wks on diet [pmol/L] INS 114350 chow HFHS	inbred	2	m	21wks	N=17	2016

Nadeau3:9	Nadeau3	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet [] HOMA_IR 114352 chow HFHS	inbred	2	m	21wks	N=17	2016

Naggert1:5	Naggert1	hormone quantification	high-fat diet	insulin [ng/mL] INS_fat18 14305	inbred w/CC7	43	both	25-27wks	N=12	2003

Naggert1:6	Naggert1	hormone quantification	high-fat diet	leptin [pg/mL] LEP_fat18 14306	inbred w/CC7	43	both	25-27wks	N=11	2003

Pletcher1:5	Pletcher1	hormone quantification	(none)	serum corticosterone, log transformed [log(µg/dL)] corticosterone_log 36005	inbred	29	m	7-10wks*	N=6	2007

Pletcher1:20	Pletcher1	hormone quantification	(none)	serum corticosterone [µg/dL] corticosterone 36020	inbred	29	m	7-10wks*	N=6	2007

Project1140:152	Project1140	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1) [ng/mL] igf1_ctrl 116644 igf1_ctrl_6 igf1_ctrl_12 igf1_ctrl_18	DO population		both	26-78 wks	N=257	2022

Project1140:155	Project1140	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1) 6 mo [ng/mL] igf1 116647 igf1_6 igf1_12 igf1_18	DO population		both	26-78 wks	N=257	2022

Reifsnyder1:13	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 16 wks [ng/mL] INS_16 11113	QTL population		m	16wks	N=204	2000

Reifsnyder1:14	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 20 wks [ng/mL] INS_20 11114	QTL population		m	20wks	N=204	2000

Reifsnyder1:15	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 24 wks [ng/mL] INS_24 11115	QTL population		m	24wks	N=204	2000

Reifsnyder1:16	Reifsnyder1	hormone quantification	(none)	leptin, 24 wks [ng/mL] LEP_24 11116	QTL population		m	24wks	N=204	2000

Schoenrock1:74	Schoenrock1	hormone quantification	various diets	basal serum corticosterone [ng/mL] CORT_basal 61274 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	18	f	8-9wks	N=11	2018

Schoenrock1:78	Schoenrock1	hormone quantification	various diets	serum corticosterone after 10 min restraint stress [ng/mL] CORT_stress 61278 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	18	f	8-9wks	N=11	2018

Schoenrock1:82	Schoenrock1	hormone quantification	various diets	change in serum corticosterone (stress minus basal) [ng/mL] CORT_chg 61282 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	18	f	8-9wks	N=11	2018

Schonfeld1:8	Schonfeld1	hormone quantification	(none)	insulin level (plasma), 30 min post injection in glucose tolerance test (10% glucose i.p., 5h fast) [ng/mL] Insulin 32311	inbred	10	both	9-13wks	N=5	2005

Shockley1:10	Shockley1	metabolic panel	high-fat diet	thyroxine (T4) [µg/dL] T4 33410 control diet high-fat diet difference	inbred	10	both	10-13wks	N=5	2008

Solberg1:21	Solberg1	hormone quantification	(none)	insulin post-challenge [µU/mL] insulinpostglucchall 15021	QTL population		both	17wks	N=243	2004

Trullas1:51	Trullas1	hormone quantification	(none)	basal corticosterone levels (plasma) [µg/dL] cortico_basal 52851	inbred	5	m	6-8wks	N=4	1993

Trullas1:52	Trullas1	hormone quantification	(none)	stress-induced corticosterone levels (plasma) [µg/dL] cortico_stress 52852	inbred	5	m	6-8wks	N=4	1993

Trullas1:53	Trullas1	hormone quantification	(none)	fold change across cohorts in corticosterone levels (plasma) (stress to basal ratio) [ratio] cortico_ratio 52853	inbred	5	m	6-8wks	N=3	1993

Xenakis2:226	Xenakis2	hormone quantification	arsenic	fasting plasma insulin (6h fast) [ng/mL] FPI 118380 iAs: 1 wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after	DO population		m	7-33wks	N=71	2022

Xenakis2:233	Xenakis2	hormone quantification	arsenic	plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection [ng/mL] PI15 118387 iAs: 1 wk before 13 wks after 25 wks after	DO population		m	7-33wks	N=72	2022

Xenakis2:236	Xenakis2	hormone quantification	arsenic	fasting plasma insulin (6h fast), coefficient of variation (CV) [%] FPI_CV 118390 iAs: 1wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after	DO population		m	7-33wks	N=73	2022

Xenakis2:243	Xenakis2	hormone quantification	arsenic	plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection, coefficient of variation (CV) [%] PI15_CV 118397 iAs: 1wk before 13 wks after 25 wks after	DO population		m	7-33wks	N=72	2022

Yuan1:1	Yuan1	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1) [ng/mL] IGF1 27001 6mo 12mo 18mo	inbred	33	both		N=7	2007

Yuan3:76	Yuan3	metabolic panel	(none)	thyroxine (serum T4) [µg/dL] T4 24476 6mo 12mo 18mo	inbred	32	both		N=7	2008

Zhang1:44	Zhang1	hormone quantification	western diet	plasma insulin [ng/mL] Insulin_mean 27944	QTL population		f	18wks	N=266	2012

Zhang1:45	Zhang1	hormone quantification	western diet	ln(insulin) Ln_insulin 27945	QTL population		f	18wks	N=266	2012

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