Project measure / variable:   Naggert1   INS_fat18

ID, description, units MPD:14305   INS_fat18   insulin   [ng/mL]  
high-fat diet study
Data set, strains Naggert1   inbred w/CC7   43 strains     sex: both     age: 25-27wks
Procedure hormone quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Naggert1 - insulin



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested41 strains42 strains
Mean of the strain means1.06   ng/mL 1.77   ng/mL
Median of the strain means0.896   ng/mL 1.50   ng/mL
SD of the strain means± 0.515 ± 1.02
Coefficient of variation (CV)0.486 0.574
Min–max range of strain means0.544   –   3.05   ng/mL 0.534   –   4.53   ng/mL
Mean sample size per strain11.8   mice 11.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 138.8409 138.8409 107.2507 < 0.0001
strain 39 463.5305 11.8854 9.1811 < 0.0001
sex:strain 39 159.9436 4.1011 3.168 < 0.0001
Residuals 880 1139.1997 1.2945


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.564 0.148   10 0.047 0.263 0.335, 0.829 -0.96
129S1/SvImJ m 2.2 1.51   20 0.337 0.684 0.42
A/J f 0.544 0.134   12 0.0388 0.247 0.324, 0.826 -1.0
A/J m 0.534 0.225   10 0.0713 0.422 0.275, 1.0 -1.22
AKR/J f 1.56 0.834   18 0.197 0.534 0.516, 3.34 0.97
AKR/J m 3.68 2.31   13 0.641 0.628 0.424, 7.2 1.87
BALB/cByJ f 1.48 0.848   12 0.245 0.573 0.412, 3.27 0.82
BALB/cByJ m 1.51 0.517   9 0.172 0.341 0.685, 2.17 -0.26
BALB/cJ f 1.19 0.787   14 0.21 0.66 0.442, 2.9 0.25
BALB/cJ m 0.938 0.43   10 0.136 0.458 0.484, 1.68 -0.82
BTBR T+ Itpr3tf/J f 0.737 0.288   11 0.0868 0.391 0.432, 1.53 -0.63
BTBR T+ Itpr3tf/J m 3.32 2.4   13 0.667 0.724 0.621, 7.12 1.52
BUB/BnJ f 0.952 0.885   9 0.295 0.93 0.477, 3.28 -0.21
BUB/BnJ m 1.82 0.798   10 0.252 0.438 1.1, 3.08 0.05
C3H/HeJ f 0.873 0.263   10 0.0833 0.302 0.617, 1.37 -0.36
C3H/HeJ m 1.48 1.46   10 0.461 0.985 0.554, 5.23 -0.29
C57BL/10J f 0.677 0.554   12 0.16 0.818 0.337, 2.35 -0.74
C57BL/10J m 1.63 0.907   9 0.302 0.555 0.679, 3.75 -0.14
C57BL/6J f 0.837 0.757   10 0.239 0.904 0.168, 2.83 -0.43
C57BL/6J m 0.639 0.542   11 0.164 0.848 0.049, 2.1 -1.12
C57BLKS/J f 0.896 0.61   11 0.184 0.682 0.402, 2.54 -0.32
C57BLKS/J m 1.33 0.767   11 0.231 0.575 0.543, 2.64 -0.44
C57BR/cdJ f 0.75 0.343   15 0.0885 0.457 0.366, 1.8 -0.6
C57BR/cdJ m 1.44 1.02   14 0.272 0.707 0.353, 3.74 -0.33
C57L/J f 0.548 0.253   11 0.0763 0.462 0.279, 1.14 -0.99
C57L/J m 0.816 0.399   10 0.126 0.488 0.425, 1.55 -0.94
C58/J f 1.09 1.32   10 0.416 1.2 0.267, 4.2 0.06
C58/J m 1.04 0.659   13 0.183 0.636 0.446, 2.41 -0.72
CAST/EiJ f 1.14 1.02   13 0.282 0.891 0.339, 3.52 0.16
CAST/EiJ m 2.4 2.08   10 0.659 0.87 0.559, 6.12 0.62
CBA/J f 1.32 0.827   20 0.185 0.627 0.587, 3.91 0.51
CBA/J m 3.34 2.11   19 0.485 0.632 0.429, 7.11 1.54
CE/J f 1.46 0.931   8 0.329 0.638 0.306, 2.67 0.78
CE/J m 1.54 1.41   17 0.343 0.92 0.406, 6.32 -0.23
CZECHII/EiJ f 0.611 0.231   9 0.077 0.378 0.286, 0.922 -0.87
CZECHII/EiJ m 0.719 0.384   11 0.116 0.534 0.372, 1.4 -1.04
DBA/1J f 1.02 0.498   11 0.15 0.487 0.413, 1.99 -0.08
DBA/1J m 2.93 1.8   11 0.541 0.614 0.4, 6.18 1.14
DBA/2J f 2.64 1.82   14 0.485 0.687 0.519, 5.89 3.07
DBA/2J m 4.29 2.36   14 0.63 0.55 0.189, 8.77 2.47
FVB/NJ f 0.731 0.348   13 0.0966 0.476 0.406, 1.56 -0.64
FVB/NJ m 0.994 0.625   9 0.208 0.628 0.294, 2.21 -0.77
I/LnJ f 1.07 0.914   12 0.264 0.858 0.258, 3.73 0.02
I/LnJ m 2.08 1.43   9 0.478 0.687 0.893, 5.69 0.3
JF1/MsJ f 1.3 0.629   13 0.174 0.484 0.4, 2.56 0.47
JF1/MsJ m 1.63 1.56   19 0.358 0.958 -0.14
KK/HlJ f 3.05 2.01   18 0.473 0.658 0.549, 6.11 3.87
KK/HlJ m 4.53 1.53   6 0.624 0.337 1.81, 5.73 2.71
LP/J f 0.728 0.327   15 0.0843 0.449 0.0155, 1.09 -0.64
LP/J m 3.26 1.89   20 0.422 0.579 0.764, 8.17 1.46
MA/MyJ m 1.26 1.35   7 0.512 1.08 0.488, 4.27 -0.5
MOLF/EiJ m 0.606 0.171   8 0.0605 0.282 0.37, 0.873 -1.15
MSM/MsJ f 0.644 0.235   9 0.0783 0.365 0.348, 0.96 -0.81
MSM/MsJ m 1.57 0.981   12 0.283 0.625 0.506, 3.5 -0.2
NOD/ShiLtJ f 1.7 1.96   8 0.694 1.16 0.245, 6.03 1.25
NOD/ShiLtJ m 1.63 0.771   10 0.244 0.473 0.538, 3.11 -0.14
NON/ShiLtJ f 0.766 0.578   10 0.183 0.754 -0.57
NON/ShiLtJ m 1.12 0.616   14 0.165 0.548 0.532, 2.91 -0.64
NZB/BlNJ f 0.736 0.239   13 0.0664 0.325 0.431, 1.26 -0.63
NZB/BlNJ m 2.02 1.93   12 0.557 0.957 0.44, 6.56 0.24
NZW/LacJ f 1.43 0.691   17 0.168 0.484 0.763, 3.02 0.72
NZW/LacJ m 2.38 1.61   14 0.432 0.678 0.659, 5.05 0.6
PERA/EiJ f 1.43 1.52   10 0.48 1.06 0.433, 4.55 0.72
PERA/EiJ m 0.559 0.103   7 0.0388 0.183 0.429, 0.688 -1.19
PL/J f 1.16 0.383   9 0.128 0.329 0.698, 1.87 0.2
PL/J m 2.61 1.11   11 0.336 0.427 0.397, 4.54 0.82
PWK/PhJ f 0.684 0.447   13 0.124 0.654 0.294, 1.57 -0.73
PWK/PhJ m 1.46 0.668   14 0.178 0.459 0.539, 2.84 -0.31
RF/J f 1.32 1.09   14 0.291 0.824 0.497, 4.35 0.51
RF/J m 2.6 1.53   9 0.509 0.589 0.754, 4.83 0.81
RIIIS/J f 0.628 0.424   9 0.141 0.676 0.4, 1.75 -0.84
RIIIS/J m 1.5 0.901   9 0.3 0.602 0.633, 3.44 -0.27
SEA/GnJ f 0.857 0.359   16 0.0898 0.419 0.256, 1.66 -0.39
SEA/GnJ m 1.04 0.5   12 0.144 0.482 0.5, 2.17 -0.72
SJL/J f 0.833 0.389   10 0.123 0.468 0.402, 1.48 -0.44
SJL/J m 1.04 1.07   9 0.357 1.03 0.08, 3.6 -0.72
SM/J f 0.932 0.637   9 0.212 0.683 0.369, 2.5 -0.25
SM/J m 1.06 0.646   10 0.204 0.609 0.275, 2.15 -0.7
SPRET/EiJ f 0.737 0.489   5 0.219 0.663 0.353, 1.56 -0.63
SWR/J f 0.996 0.949   13 0.263 0.953 0.431, 3.74 -0.12
SWR/J m 1.12 0.78   14 0.208 0.698 0.43, 3.12 -0.64
WSB/EiJ f 0.79 0.381   11 0.115 0.482 0.441, 1.56 -0.52
WSB/EiJ m 0.804 0.787   13 0.218 0.979 0.036, 3.14 -0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5643 0.3598 1.2705 0.0
129S1/SvImJ m 2.2048 0.2544 2.7041 1.7055
A/J f 0.5444 0.3284 1.1891 0.0
A/J m 0.5336 0.3598 1.2398 0.0
AKR/J f 1.5605 0.2682 2.0868 1.0342
AKR/J m 3.678 0.3156 4.2973 3.0587
BALB/cByJ f 1.479 0.3284 2.1236 0.8344
BALB/cByJ m 1.5144 0.3793 2.2588 0.7701
BALB/cJ f 1.1924 0.3041 1.7892 0.5956
BALB/cJ m 0.9383 0.3598 1.6445 0.2321
BTBR T+ Itpr3tf/J f 0.7367 0.3431 1.41 0.0634
BTBR T+ Itpr3tf/J m 3.3219 0.3156 3.9413 2.7026
BUB/BnJ f 0.9519 0.3793 1.6962 0.2075
BUB/BnJ m 1.823 0.3598 2.5292 1.1168
C3H/HeJ f 0.8728 0.3598 1.579 0.1666
C3H/HeJ m 1.4803 0.3598 2.1865 0.7741
C57BL/10J f 0.6766 0.3284 1.3212 0.0319
C57BL/10J m 1.6338 0.3793 2.3781 0.8894
C57BL/6J f 0.8368 0.3598 1.543 0.1306
C57BL/6J m 0.6395 0.3431 1.3128 0.0
C57BLKS/J f 0.8955 0.3431 1.5688 0.2222
C57BLKS/J m 1.3334 0.3431 2.0067 0.6601
C57BR/cdJ f 0.7503 0.2938 1.3269 0.1738
C57BR/cdJ m 1.4419 0.3041 2.0387 0.8451
C57L/J f 0.5481 0.3431 1.2214 0.0
C57L/J m 0.8162 0.3598 1.5224 0.11
C58/J f 1.0936 0.3598 1.7998 0.3874
C58/J m 1.0364 0.3156 1.6557 0.417
CAST/EiJ f 1.1427 0.3156 1.762 0.5233
CAST/EiJ m 2.3955 0.3598 3.1017 1.6893
CBA/J f 1.3198 0.2544 1.8191 0.8204
CBA/J m 3.3444 0.261 3.8567 2.8321
CE/J f 1.4594 0.4023 2.2489 0.6699
CE/J m 1.536 0.276 2.0776 0.9944
CZECHII/EiJ f 0.6112 0.3793 1.3556 0.0
CZECHII/EiJ m 0.7185 0.3431 1.3918 0.0452
DBA/1J f 1.0226 0.3431 1.6959 0.3493
DBA/1J m 2.9264 0.3431 3.5997 2.2531
DBA/2J f 2.644 0.3041 3.2408 2.0472
DBA/2J m 4.2864 0.3041 4.8832 3.6895
FVB/NJ f 0.7311 0.3156 1.3504 0.1117
FVB/NJ m 0.9943 0.3793 1.7387 0.25
I/LnJ f 1.0656 0.3284 1.7102 0.4209
I/LnJ m 2.0848 0.3793 2.8291 1.3404
JF1/MsJ f 1.2988 0.3156 1.9181 0.6794
JF1/MsJ m 1.6291 0.261 2.1414 1.1168
KK/HlJ f 3.0461 0.2682 3.5725 2.5198
KK/HlJ m 4.5283 0.4645 5.44 3.6167
LP/J f 0.7278 0.2938 1.3043 0.1512
LP/J m 3.2597 0.2544 3.759 2.7604
MSM/MsJ f 0.6438 0.3793 1.3881 0.0
MSM/MsJ m 1.5691 0.3284 2.2137 0.9244
NOD/ShiLtJ f 1.6972 0.4023 2.4868 0.9077
NOD/ShiLtJ m 1.63 0.3598 2.3362 0.9238
NON/ShiLtJ f 0.766 0.3598 1.4722 0.0598
NON/ShiLtJ m 1.1238 0.3041 1.7206 0.527
NZB/BlNJ f 0.7359 0.3156 1.3553 0.1166
NZB/BlNJ m 2.0163 0.3284 2.661 1.3717
NZW/LacJ f 1.4262 0.276 1.9678 0.8846
NZW/LacJ m 2.3814 0.3041 2.9782 1.7845
PERA/EiJ f 1.4334 0.3598 2.1396 0.7272
PERA/EiJ m 0.5593 0.43 1.4033 0.0
PL/J f 1.1628 0.3793 1.9071 0.4184
PL/J m 2.607 0.3431 3.2803 1.9337
PWK/PhJ f 0.6842 0.3156 1.3035 0.0648
PWK/PhJ m 1.4556 0.3041 2.0524 0.8588
RF/J f 1.321 0.3041 1.9178 0.7242
RF/J m 2.5957 0.3793 3.34 1.8513
RIIIS/J f 0.6278 0.3793 1.3721 0.0
RIIIS/J m 1.4964 0.3793 2.2408 0.7521
SEA/GnJ f 0.8574 0.2844 1.4156 0.2991
SEA/GnJ m 1.0367 0.3284 1.6813 0.392
SJL/J f 0.8328 0.3598 1.539 0.1266
SJL/J m 1.0409 0.3793 1.7852 0.2965
SM/J f 0.9324 0.3793 1.6768 0.1881
SM/J m 1.061 0.3598 1.7672 0.3548
SWR/J f 0.9959 0.3156 1.6153 0.3766
SWR/J m 1.1164 0.3041 1.7132 0.5196
WSB/EiJ f 0.79 0.3431 1.4633 0.1167
WSB/EiJ m 0.804 0.3156 1.4233 0.1847


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.3846 0.2203 1.817 0.9521
A/J both 0.539 0.2436 1.0171 0.0609
AKR/J both 2.6193 0.2071 3.0256 2.2129
BALB/cByJ both 1.4967 0.2509 1.9891 1.0044
BALB/cJ both 1.0654 0.2355 1.5277 0.6031
BTBR T+ Itpr3tf/J both 2.0293 0.2331 2.4867 1.5719
BUB/BnJ both 1.3874 0.2614 1.9005 0.8744
C3H/HeJ both 1.1765 0.2544 1.6759 0.6772
C57BL/10J both 1.1552 0.2509 1.6475 0.6628
C57BL/6J both 0.7381 0.2486 1.226 0.2503
C57BLKS/J both 1.1145 0.2426 1.5905 0.6384
C57BR/cdJ both 1.0961 0.2114 1.5111 0.6812
C57L/J both 0.6821 0.2486 1.17 0.1943
C58/J both 1.065 0.2393 1.5346 0.5954
CAST/EiJ both 1.7691 0.2393 2.2387 1.2995
CBA/J both 2.3321 0.1823 2.6898 1.9744
CE/J both 1.4977 0.2439 1.9764 1.019
CZECHII/EiJ both 0.6649 0.2557 1.1667 0.163
DBA/1J both 1.9745 0.2426 2.4506 1.4984
DBA/2J both 3.4652 0.215 3.8872 3.0432
FVB/NJ both 0.8627 0.2467 1.3469 0.3785
I/LnJ both 1.5752 0.2509 2.0675 1.0828
JF1/MsJ both 1.4639 0.2048 1.8658 1.0621
KK/HlJ both 3.7872 0.2682 4.3136 3.2609
LP/J both 1.9937 0.1943 2.3751 1.6124
MSM/MsJ both 1.1064 0.2509 1.5988 0.6141
NOD/ShiLtJ both 1.6636 0.2698 2.1932 1.134
NON/ShiLtJ both 0.9449 0.2355 1.4072 0.4826
NZB/BlNJ both 1.3761 0.2277 1.8231 0.9292
NZW/LacJ both 1.9038 0.2053 2.3067 1.5008
PERA/EiJ both 0.9963 0.2804 1.5466 0.4461
PL/J both 1.8849 0.2557 2.3867 1.383
PWK/PhJ both 1.0699 0.2191 1.4999 0.6398
RF/J both 1.9583 0.2431 2.4354 1.4813
RIIIS/J both 1.0621 0.2682 1.5885 0.5358
SEA/GnJ both 0.947 0.2172 1.3734 0.5206
SJL/J both 0.9368 0.2614 1.4499 0.4238
SM/J both 0.9967 0.2614 1.5097 0.4837
SWR/J both 1.0562 0.2191 1.4862 0.6261
WSB/EiJ both 0.797 0.2331 1.2544 0.3396




  GWAS USING LINEAR MIXED MODELS