MPD: Measures involving hormone quantification

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Attie2:80	Attie2	hormone quantification	high-fat high-sucrose diet	plasma insulin after diet (4h fast) [ng/mL] INS 110697 wk: 6 10 14 22	DO population		both	10-26wks	N=250	2018

Attie2:97	Attie2	hormone quantification	high-fat high-sucrose diet	plasma adiponectin measured at the time oral glucose tolerance test performed after ~14 wks on diet (4h fast) [µg/mL] adiponectin 110714	DO population		both	18wks	N=144	2018

Attie2:98	Attie2	hormone quantification	high-fat high-sucrose diet	plasma leptin measured at the time oral glucose tolerance test performed after ~14 wks on diet (4h fast) [ng/mL] leptin 110715	DO population		both	18wks	N=96	2018

Attie2:100	Attie2	hormone quantification	high-fat high-sucrose diet	amount of insulin per islet after diet [ng/mL] INS_per_islet 110717	DO population		both	19-26wks	N=241	2018

Attie2:101	Attie2	hormone quantification	high-fat high-sucrose diet	whole pancreas insulin content after diet (insulin content per islet times number of islets) [ng/mL] INS_per_pancreas 110718	DO population		both	19-26wks	N=241	2018

Attie2:102	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose [ng/mL] INS_GLU 110719 3.3 mM 8.3 mM 16.7 mM	DO population		both	19-26wks	N=242	2018

Attie2:105	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] INS_GLU3p3_KCl 110722	DO population		both	19-26wks	N=240	2018

Attie2:106	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 [ng/mL] INS_GLU8p3_GLP1 110723	DO population		both	19-26wks	N=240	2018

Attie2:107	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) [ng/mL] INS_GLU8p3_AA 110724	DO population		both	19-26wks	N=240	2018

Attie2:108	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid [ng/mL] INS_GLU16p7_PA 110725	DO population		both	19-26wks	N=240	2018

Attie2:109	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_fc_G3p3 110726	DO population		both	19-26wks	N=240	2018

Attie2:110	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose, expressed as fold-change over that observed with 3.3.mM glucose [ratio] INS_GLU16p7_fc_G3p3 110727	DO population		both	19-26wks	N=240	2018

Attie2:111	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU3p3__KCl_fc_G3p3 110728	DO population		both	19-26wks	N=240	2018

Attie2:112	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G3p3 110729	DO population		both	19-26wks	N=240	2018

Attie2:113	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_AA_fc_G3p3 110730	DO population		both	19-26wks	N=240	2018

Attie2:114	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus palmitic acid, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU16p7_PA_fc_G3p3 110731	DO population		both	19-26wks	N=240	2018

Attie2:115	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 8.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G8p3 110732	DO population		both	19-26wks	N=240	2018

Attie2:116	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as fold-change over that observed with 8.3 mM glucose [ratio] INS_GLU8p3_AA_fc_G8p3 110733	DO population		both	19-26wks	N=240	2018

Attie2:117	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid, expressed as fold-change over that observed with 16.7 mM glucose [ratio] INS_GLU16p7_PA_fc_G16p7 110734	DO population		both	19-26wks	N=240	2018

Attie2:118	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose, expressed as a percentage of total insulin per mouse [%] INS_pct_GLU 110735 3.3 mM 8.3 mM 16.7 mM	DO population		both	19-26wks	N=241	2018

Attie2:121	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as a percentage of total insulin per mouse [%] INS_GLU3p3_KCl_pct 110738	DO population		both	19-26wks	N=239	2018

Attie2:122	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as a percentage of total insulin per mouse [%] INS_GLU8p3_GLP1_pct 110739	DO population		both	19-26wks	N=239	2018

Attie2:123	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as a percentage of total insulin per mouse [%] INS_GLU8p3_AA_pct 110740	DO population		both	19-26wks	N=239	2018

Attie2:124	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid, expressed as a percentage of total insulin per mouse [%] INS_GLU16p7_PA_pct 110741	DO population		both	19-26wks	N=239	2018

Attie2:125	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose (geometric mean) [ng/mL] INS_gm_GLU 110742 3.3 mM 8.3 mM 16.7 mM	DO population		both	19-26wks	N=242	2018

Attie2:128	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl (geometric mean) [ng/mL] INS_gm_GLU3p3_KCl 110745	DO population		both	19-26wks	N=240	2018

Attie2:129	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 (geometric mean) [ng/mL] INS_gm_GLU8p3_GLP1 110746	DO population		both	19-26wks	N=240	2018

Attie2:130	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) (geometric mean) [ng/mL] INS_gm_GLU8p3_AA 110747	DO population		both	19-26wks	N=240	2018

Attie2:131	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid (geometric mean) [ng/mL] INS_gm_GLU16p7_PA 110748	DO population		both	19-26wks	N=240	2018

Attie2:132	Attie2	hormone quantification	high-fat high-sucrose diet	amount of glucagon per islet after diet [ng/mL] GCG_per_islet 110749	DO population		both	19-26wks	N=241	2018

Attie2:133	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo glucagon secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] GCG_GLU3p3_KCl 110750	DO population		both	19-26wks	N=182	2018

Attie2:134	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo glucagon secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as a percentage of total glucagon per mouse [%] GCG_GLU3p3_KCl_pct 110751	DO population		both	19-26wks	N=182	2018

Auwerx1:85	Auwerx1	hormone quantification	high-fat diet	insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 111264 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:87	Auwerx1	hormone quantification	high-fat diet	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 111266 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:89	Auwerx1	hormone quantification	high-fat diet	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 111268 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx1:91	Auwerx1	hormone quantification	high-fat diet	insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) [AUC] ogtt_ins_auc 111270 CD HFD	BXD w/par	57	m	17wks	N=4	2016

Auwerx2:73	Auwerx2	hormone quantification	(none)	insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 114601 CD HFD	inbred w/CC8	9	both	16wks	N=4	2021

Auwerx2:75	Auwerx2	hormone quantification	(none)	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 114603 CD HFD	inbred w/CC8	8	both	16wks	N=4	2021

Auwerx2:77	Auwerx2	hormone quantification	(none)	insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 114605 CD HFD	inbred w/CC8	8	both	16wks	N=4	2021

Beamer2:2	Beamer2	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1), normalized [ng/mL] IGF1_adj 11202	QTL population		f	16wks	N=999	2001

Bennett4:93	Bennett4	hormone quantification	various diets 2	plasma insulin amount, baseline [ng/mL] INS_base 114787 diet: HP group HFHS group	CC	22	f	8-11wks	N=5	2021

Bennett4:95	Bennett4	hormone quantification	various diets 2	plasma insulin amount, post-diet [ng/mL] INS_post 114789 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Bennett4:97	Bennett4	hormone quantification	various diets 2	plasma glucose to insulin ratio, baseline [ratio] GLU_INS_base 114791 diet: HP group HFHS group	CC	22	f	8-11wks	N=5	2021

Bennett4:99	Bennett4	hormone quantification	various diets 2	plasma glucose to insulin ratio, post-diet [ratio] GLU_INS_post 114793 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Brockmann1:29	Brockmann1	hormone quantification	(none)	leptin level [ng/mL] leptin 21509	QTL population		both	6wks	N=201	2009

Brockmann1:30	Brockmann1	hormone quantification	(none)	insulin level [pmol/L] insulin 21510	QTL population		both	6wks	N=201	2009

Brockmann1:31	Brockmann1	hormone quantification	(none)	IGF-1 level [ng/mL] igf1 21511	QTL population		both	6wks	N=201	2009

Brockmann1:32	Brockmann1	hormone quantification	(none)	leptin level, log10 transformed [log(ng/mL)] lg_lept 21512	QTL population		both	6wks	N=201	2009

Brockmann1:33	Brockmann1	hormone quantification	(none)	insulin level, log10 transformed [log(pmol/L)] lg_ins 21513	QTL population		both	6wks	N=201	2009

Brockmann1:34	Brockmann1	hormone quantification	(none)	IGF1 level, log10 transformed [log(ng/mL)] lg_igf1 21514	QTL population		both	6wks	N=201	2009

Cheverud1:45	Cheverud1	hormone quantification	high-fat diet	insulin (serum) [ng/mL] insulin 17840 control diet high-fat diet	LGXSM w/par	17	both	20-30wks	N=8	2004

Cheverud1:47	Cheverud1	hormone quantification	high-fat diet	leptin (serum) [pg/mL] leptin 17841 control diet high-fat diet	LGXSM w/par	10	both	20-30wks	N=6	2004

Cowell1:1	Cowell1	hormone quantification	Staphylococcus aureus	fold-change in serum IL-6 levels 24h post-infection compared to controls [ratio] IL6 49001	inbred	13	f	8wks	N=3	2012

Donahue1:16	Donahue1	hormone quantification	(none)	osteocalcin (serum OC) [ng/mL] osteocalcin 11530	inbred w/CC7	30	both	15-16wks	N=9	2002

Donahue1:18	Donahue1	hormone quantification	(none)	insulin-like growth factor 1 (adjusted serum IGF-1) [ng/mL] IGF_1 11532	inbred w/CC7	30	both	15-16wks	N=9	2002

Farmer1:29	Farmer1	hormone quantification	(none)	lgG2a antibodies against escherichia coli membrane antigens [ng/ml] IgG2aantiECM 11329	QTL population		both	6wks	N=206	2001

Farmer1:30	Farmer1	hormone quantification	(none)	levels of total lgG reactivity against escherichia coli membrane (ECM) antigens [ng/ml] IgGantiECM 11330	QTL population		both	6wks	N=206	2001

Farmer1:31	Farmer1	hormone quantification	(none)	secretory IgA in collected blood [ng/ml] IgA 11331	QTL population		both	6wks	N=206	2001

Farmer1:32	Farmer1	hormone quantification	(none)	levels of IgA secreted in feces [ng/ml] IgAfeces 11332	QTL population		both	6wks	N=206	2001

Ishimori1:17	Ishimori1	hormone quantification	high-fat diet	parathyroid hormone [pg/mL] PTH 14017	QTL population		f	20wks	N=294	2004

Ishimori1:18	Ishimori1	hormone quantification	high-fat diet	parathyroid hormone, log transformed [log(pg/mL)] PTH_log 14018	QTL population		f	20wks	N=294	2004

JaxCC1:9201	JaxCC1	hormone quantification	(none)	insulin (plasma) [pg/mL] insulin 89201	CC	18	both	17-19wks	N=6	2017

JaxKOMP-EAP:445	JaxKOMP-EAP	hormone quantification	(none)	insulin (plasma) [pg/mL] insulin 100637	KOMP	410	both	18wks	N=14	2016

Kim1:3	Kim1	hormone quantification	(none)	non-fasted insulin level [ng/mL] Insulin 11403	QTL population		m	26wks	N=206	2001

Leiter2:16	Leiter2	hormone quantification	(none)	leptin in plasma [ng/mL] Leptin 24016	QTL population		f	14-40wks	N=310	2009

Leiter2:17	Leiter2	hormone quantification	(none)	insulin in plasma [ng/mL] Insulin 24017	QTL population		f	14-40wks	N=310	2009

Nadeau2:7	Nadeau2	hormone quantification	high-fat high-sucrose diet	insulin (plasma, 16h fast) [pmol/L] INS 53022	B6.A consomic w/par	24	m	21wks	N=39	2015

Nadeau2:8	Nadeau2	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (HOMA-IR, 16h fast) HOMA_IR 53023	B6.A consomic w/par	24	m	21wks	N=39	2015

Nadeau3:7	Nadeau3	hormone quantification	high-fat high-sucrose diet	insulin amount (overnight fast) after 16 wks on diet [pmol/L] INS 114350 chow HFHS	inbred	2	m	21wks	N=17	2016

Nadeau3:9	Nadeau3	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet [] HOMA_IR 114352 chow HFHS	inbred	2	m	21wks	N=17	2016

Naggert1:5	Naggert1	hormone quantification	high-fat diet	insulin [ng/mL] INS_fat18 14305	inbred w/CC7	43	both	25-27wks	N=12	2003

Naggert1:6	Naggert1	hormone quantification	high-fat diet	leptin [pg/mL] LEP_fat18 14306	inbred w/CC7	43	both	25-27wks	N=11	2003

Pletcher1:5	Pletcher1	hormone quantification	(none)	serum corticosterone, log transformed [log(µg/dL)] corticosterone_log 36005	inbred	29	m	7-10wks*	N=6	2007

Pletcher1:20	Pletcher1	hormone quantification	(none)	serum corticosterone [µg/dL] corticosterone 36020	inbred	29	m	7-10wks*	N=6	2007

Reifsnyder1:13	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 16 wks [ng/mL] INS_16 11113	QTL population		m	16wks	N=204	2000

Reifsnyder1:14	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 20 wks [ng/mL] INS_20 11114	QTL population		m	20wks	N=204	2000

Reifsnyder1:15	Reifsnyder1	hormone quantification	(none)	insulin (plasma), 24 wks [ng/mL] INS_24 11115	QTL population		m	24wks	N=204	2000

Reifsnyder1:16	Reifsnyder1	hormone quantification	(none)	leptin, 24 wks [ng/mL] LEP_24 11116	QTL population		m	24wks	N=204	2000

Schoenrock1:74	Schoenrock1	hormone quantification	various diets	basal serum corticosterone [ng/mL] CORT_basal 61274 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	18	f	8-9wks	N=11	2018

Schoenrock1:78	Schoenrock1	hormone quantification	various diets	serum corticosterone after 10 min restraint stress [ng/mL] CORT_stress 61278 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	18	f	8-9wks	N=11	2018

Schoenrock1:82	Schoenrock1	hormone quantification	various diets	change in serum corticosterone (stress minus basal) [ng/mL] CORT_chg 61282 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet	CC RIX	18	f	8-9wks	N=11	2018

Schonfeld1:8	Schonfeld1	hormone quantification	(none)	insulin level (plasma), 30 min post injection in glucose tolerance test (10% glucose i.p., 5h fast) [ng/mL] Insulin 32311	inbred	10	both	9-13wks	N=5	2005

Solberg1:9	Solberg1	hormone quantification	(none)	thyroid-stimulating hormone [ng/mL] TSH 15009	QTL population		both	15wks	N=243	2004

Solberg1:13	Solberg1	hormone quantification	(none)	basal plasma corticosterone level [ng/mL] CORT0 15013	QTL population		both	not specified	N=243	2004

Solberg1:14	Solberg1	hormone quantification	(none)	plasma corticosterone response to a 10 min restraint stress [ng/mL] CORT10 15014	QTL population		both	not specified	N=243	2004

Solberg1:21	Solberg1	hormone quantification	(none)	insulin post-challenge [µU/mL] insulinpostglucchall 15021	QTL population		both	17wks	N=243	2004

Trullas1:51	Trullas1	hormone quantification	(none)	basal corticosterone levels (plasma) [µg/dL] cortico_basal 52851	inbred	5	m	6-8wks	N=4	1993

Trullas1:52	Trullas1	hormone quantification	(none)	stress-induced corticosterone levels (plasma) [µg/dL] cortico_stress 52852	inbred	5	m	6-8wks	N=4	1993

Trullas1:53	Trullas1	hormone quantification	(none)	fold change across cohorts in corticosterone levels (plasma) (stress to basal ratio) [ratio] cortico_ratio 52853	inbred	5	m	6-8wks	N=3	1993

Xenakis2:226	Xenakis2	hormone quantification	arsenic	fasting plasma insulin (6h fast) [ng/mL] FPI 118380 iAs: 1 wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after	DO population		m	7-33wks	N=71	2022

Xenakis2:233	Xenakis2	hormone quantification	arsenic	plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection [ng/mL] PI15 118387 iAs: 1 wk before 13 wks after 25 wks after	DO population		m	7-33wks	N=72	2022

Xenakis2:236	Xenakis2	hormone quantification	arsenic	fasting plasma insulin (6h fast), coefficient of variation (CV) [%] FPI_CV 118390 iAs: 1wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after	DO population		m	7-33wks	N=73	2022

Xenakis2:243	Xenakis2	hormone quantification	arsenic	plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection, coefficient of variation (CV) [%] PI15_CV 118397 iAs: 1wk before 13 wks after 25 wks after	DO population		m	7-33wks	N=72	2022

Yuan1:1	Yuan1	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1) [ng/mL] IGF1 27001 6mo 12mo 18mo	inbred	33	both		N=7	2007

Zhang1:44	Zhang1	hormone quantification	western diet	plasma insulin [ng/mL] Insulin_mean 27944	QTL population		f	18wks	N=266	2012

Zhang1:45	Zhang1	hormone quantification	western diet	ln(insulin) Ln_insulin 27945	QTL population		f	18wks	N=266	2012

Attie2

hormone quantification

high-fat high-sucrose diet

plasma insulin after diet (4h fast) [ng/mL] INS 110697 wk: 6 10 14 22

DO population

both

10-26wks

N=250

2018

Attie2

hormone quantification

high-fat high-sucrose diet

plasma adiponectin measured at the time oral glucose tolerance test performed after ~14 wks on diet (4h fast) [µg/mL] adiponectin 110714

DO population

both

18wks

N=144

2018

Attie2

hormone quantification

high-fat high-sucrose diet

plasma leptin measured at the time oral glucose tolerance test performed after ~14 wks on diet (4h fast) [ng/mL] leptin 110715

DO population

both

18wks

N=96

2018

Attie2

hormone quantification

high-fat high-sucrose diet

amount of insulin per islet after diet [ng/mL] INS_per_islet 110717

DO population

both

19-26wks

N=241

2018

Attie2

hormone quantification

high-fat high-sucrose diet

whole pancreas insulin content after diet (insulin content per islet times number of islets) [ng/mL] INS_per_pancreas 110718

DO population

both

19-26wks

N=241

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to glucose [ng/mL] INS_GLU 110719 3.3 mM 8.3 mM 16.7 mM

DO population

both

19-26wks

N=242

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] INS_GLU3p3_KCl 110722

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 [ng/mL] INS_GLU8p3_GLP1 110723

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) [ng/mL] INS_GLU8p3_AA 110724

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid [ng/mL] INS_GLU16p7_PA 110725

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_fc_G3p3 110726

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 16.7 mM glucose, expressed as fold-change over that observed with 3.3.mM glucose [ratio] INS_GLU16p7_fc_G3p3 110727

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU3p3__KCl_fc_G3p3 110728

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G3p3 110729

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_AA_fc_G3p3 110730

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 16.7 mM glucose plus palmitic acid, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU16p7_PA_fc_G3p3 110731

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 8.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G8p3 110732

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as fold-change over that observed with 8.3 mM glucose [ratio] INS_GLU8p3_AA_fc_G8p3 110733

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid, expressed as fold-change over that observed with 16.7 mM glucose [ratio] INS_GLU16p7_PA_fc_G16p7 110734

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to glucose, expressed as a percentage of total insulin per mouse [%] INS_pct_GLU 110735 3.3 mM 8.3 mM 16.7 mM

DO population

both

19-26wks

N=241

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as a percentage of total insulin per mouse [%] INS_GLU3p3_KCl_pct 110738

DO population

both

19-26wks

N=239

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as a percentage of total insulin per mouse [%] INS_GLU8p3_GLP1_pct 110739

DO population

both

19-26wks

N=239

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as a percentage of total insulin per mouse [%] INS_GLU8p3_AA_pct 110740

DO population

both

19-26wks

N=239

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid, expressed as a percentage of total insulin per mouse [%] INS_GLU16p7_PA_pct 110741

DO population

both

19-26wks

N=239

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to glucose (geometric mean) [ng/mL] INS_gm_GLU 110742 3.3 mM 8.3 mM 16.7 mM

DO population

both

19-26wks

N=242

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl (geometric mean) [ng/mL] INS_gm_GLU3p3_KCl 110745

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 (geometric mean) [ng/mL] INS_gm_GLU8p3_GLP1 110746

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) (geometric mean) [ng/mL] INS_gm_GLU8p3_AA 110747

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid (geometric mean) [ng/mL] INS_gm_GLU16p7_PA 110748

DO population

both

19-26wks

N=240

2018

Attie2

hormone quantification

high-fat high-sucrose diet

amount of glucagon per islet after diet [ng/mL] GCG_per_islet 110749

DO population

both

19-26wks

N=241

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo glucagon secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] GCG_GLU3p3_KCl 110750

DO population

both

19-26wks

N=182

2018

Attie2

hormone quantification

high-fat high-sucrose diet

ex vivo glucagon secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as a percentage of total glucagon per mouse [%] GCG_GLU3p3_KCl_pct 110751

DO population

both

19-26wks

N=182

2018

Auwerx1

hormone quantification

high-fat diet

insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 111264 CD HFD

BXD w/par

57

m

17wks

N=4

2016

Auwerx1

hormone quantification

high-fat diet

insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 111266 CD HFD

BXD w/par

57

m

17wks

N=4

2016

Auwerx1

hormone quantification

high-fat diet

insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 111268 CD HFD

BXD w/par

57

m

17wks

N=4

2016

Auwerx1

hormone quantification

high-fat diet

insulin, area under curve, glucose tolerance test (20% glucose oral gavage, overnight fast) [AUC] ogtt_ins_auc 111270 CD HFD

BXD w/par

57

m

17wks

N=4

2016

Auwerx2

hormone quantification

(none)

insulin baseline, glucose tolerance test (pregavage, overnight fast) [µg/L] ogtt_ins_t0 114601 CD HFD

inbred w/CC8

9

both

16wks

N=4

2021

Auwerx2

hormone quantification

(none)

insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min [µg/L] ogtt_ins_t15 114603 CD HFD

inbred w/CC8

8

both

16wks

N=4

2021

Auwerx2

hormone quantification

(none)

insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min [µg/L] ogtt_ins_t30 114605 CD HFD

inbred w/CC8

8

both

16wks

N=4

2021

Beamer2

hormone quantification

(none)

insulin-like growth factor 1 (serum IGF-1), normalized [ng/mL] IGF1_adj 11202

QTL population

f

16wks

N=999

2001

Bennett4

hormone quantification

various diets 2

plasma insulin amount, baseline [ng/mL] INS_base 114787 diet: HP group HFHS group

CC

22

f

8-11wks

N=5

2021

Bennett4

hormone quantification

various diets 2

plasma insulin amount, post-diet [ng/mL] INS_post 114789 diet: HP group HFHS group

CC

22

f

17-20wks

N=4

2021

Bennett4

hormone quantification

various diets 2

plasma glucose to insulin ratio, baseline [ratio] GLU_INS_base 114791 diet: HP group HFHS group

CC

22

f

8-11wks

N=5

2021

Bennett4

hormone quantification

various diets 2

plasma glucose to insulin ratio, post-diet [ratio] GLU_INS_post 114793 diet: HP group HFHS group

CC

22

f

17-20wks

N=4

2021

Brockmann1

hormone quantification

(none)

leptin level [ng/mL] leptin 21509

QTL population

both

6wks

N=201

2009

Brockmann1

hormone quantification

(none)

insulin level [pmol/L] insulin 21510

QTL population

both

6wks

N=201

2009

Brockmann1

hormone quantification

(none)

IGF-1 level [ng/mL] igf1 21511

QTL population

both

6wks

N=201

2009

Brockmann1

hormone quantification

(none)

leptin level, log10 transformed [log(ng/mL)] lg_lept 21512

QTL population

both

6wks

N=201

2009

Brockmann1

hormone quantification

(none)

insulin level, log10 transformed [log(pmol/L)] lg_ins 21513

QTL population

both

6wks

N=201

2009

Brockmann1

hormone quantification

(none)

IGF1 level, log10 transformed [log(ng/mL)] lg_igf1 21514

QTL population

both

6wks

N=201

2009

Cheverud1

hormone quantification

high-fat diet

insulin (serum) [ng/mL] insulin 17840 control diet high-fat diet

LGXSM w/par

17

both

20-30wks

N=8

2004

Cheverud1

hormone quantification

high-fat diet

leptin (serum) [pg/mL] leptin 17841 control diet high-fat diet

LGXSM w/par

10

both

20-30wks

N=6

2004

Cowell1

hormone quantification

Staphylococcus aureus

fold-change in serum IL-6 levels 24h post-infection compared to controls [ratio] IL6 49001

inbred

13

f

8wks

N=3

2012

Donahue1

hormone quantification

(none)

osteocalcin (serum OC) [ng/mL] osteocalcin 11530

inbred w/CC7

30

both

15-16wks

N=9

2002

Donahue1

hormone quantification

(none)

insulin-like growth factor 1 (adjusted serum IGF-1) [ng/mL] IGF_1 11532

inbred w/CC7

30

both

15-16wks

N=9

2002

Farmer1

hormone quantification

(none)

lgG2a antibodies against escherichia coli membrane antigens [ng/ml] IgG2aantiECM 11329

QTL population

both

6wks

N=206

2001

Farmer1

hormone quantification

(none)

levels of total lgG reactivity against escherichia coli membrane (ECM) antigens [ng/ml] IgGantiECM 11330

QTL population

both

6wks

N=206

2001

Farmer1

hormone quantification

(none)

secretory IgA in collected blood [ng/ml] IgA 11331

QTL population

both

6wks

N=206

2001

Farmer1

hormone quantification

(none)

levels of IgA secreted in feces [ng/ml] IgAfeces 11332

QTL population

both

6wks

N=206

2001

Ishimori1

hormone quantification

high-fat diet

parathyroid hormone [pg/mL] PTH 14017

QTL population

f

20wks

N=294

2004

Ishimori1

hormone quantification

high-fat diet

parathyroid hormone, log transformed [log(pg/mL)] PTH_log 14018

QTL population

f

20wks

N=294

2004

JaxCC1

hormone quantification

(none)

insulin (plasma) [pg/mL] insulin 89201

CC

18

both

17-19wks

N=6

2017

JaxKOMP-EAP

hormone quantification

(none)

insulin (plasma) [pg/mL] insulin 100637

KOMP

410

both

18wks

N=14

2016

Kim1

hormone quantification

(none)

non-fasted insulin level [ng/mL] Insulin 11403

QTL population

m

26wks

N=206

2001

Leiter2

hormone quantification

(none)

leptin in plasma [ng/mL] Leptin 24016

QTL population

f

14-40wks

N=310

2009

Leiter2

hormone quantification

(none)

insulin in plasma [ng/mL] Insulin 24017

QTL population

f

14-40wks

N=310

2009

Nadeau2

hormone quantification

high-fat high-sucrose diet

insulin (plasma, 16h fast) [pmol/L] INS 53022

B6.A consomic w/par

24

m

21wks

N=39

2015

Nadeau2

hormone quantification

high-fat high-sucrose diet

homeostasis model assessment insulin resistance (HOMA-IR, 16h fast) HOMA_IR 53023

B6.A consomic w/par

24

m

21wks

N=39

2015

Nadeau3

hormone quantification

high-fat high-sucrose diet

insulin amount (overnight fast) after 16 wks on diet [pmol/L] INS 114350 chow HFHS

inbred

2

m

21wks

N=17

2016

Nadeau3

hormone quantification

high-fat high-sucrose diet

homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet [] HOMA_IR 114352 chow HFHS

inbred

2

m

21wks

N=17

2016

Naggert1

hormone quantification

high-fat diet

insulin [ng/mL] INS_fat18 14305

inbred w/CC7

43

both

25-27wks

N=12

2003

Naggert1

hormone quantification

high-fat diet

leptin [pg/mL] LEP_fat18 14306

inbred w/CC7

43

both

25-27wks

N=11

2003

Pletcher1

hormone quantification

(none)

serum corticosterone, log transformed [log(µg/dL)] corticosterone_log 36005

inbred

29

m

7-10wks*

N=6

2007

Pletcher1

hormone quantification

(none)

serum corticosterone [µg/dL] corticosterone 36020

inbred

29

m

7-10wks*

N=6

2007

Reifsnyder1

hormone quantification

(none)

insulin (plasma), 16 wks [ng/mL] INS_16 11113

QTL population

m

16wks

N=204

2000

Reifsnyder1

hormone quantification

(none)

insulin (plasma), 20 wks [ng/mL] INS_20 11114

QTL population

m

20wks

N=204

2000

Reifsnyder1

hormone quantification

(none)

insulin (plasma), 24 wks [ng/mL] INS_24 11115

QTL population

m

24wks

N=204

2000

Reifsnyder1

hormone quantification

(none)

leptin, 24 wks [ng/mL] LEP_24 11116

QTL population

m

24wks

N=204

2000

Schoenrock1

hormone quantification

various diets

basal serum corticosterone [ng/mL] CORT_basal 61274 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet

CC RIX

18

f

8-9wks

N=11

2018

Schoenrock1

hormone quantification

various diets

serum corticosterone after 10 min restraint stress [ng/mL] CORT_stress 61278 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet

CC RIX

18

f

8-9wks

N=11

2018

Schoenrock1

hormone quantification

various diets

change in serum corticosterone (stress minus basal) [ng/mL] CORT_chg 61282 standard diet protein-deficient diet methyl-enriched diet vitamin D-deficient diet

CC RIX

18

f

8-9wks

N=11

2018

Schonfeld1

hormone quantification

(none)

insulin level (plasma), 30 min post injection in glucose tolerance test (10% glucose i.p., 5h fast) [ng/mL] Insulin 32311

inbred

10

both

9-13wks

N=5

2005

Solberg1

hormone quantification

(none)

thyroid-stimulating hormone [ng/mL] TSH 15009

QTL population

both

15wks

N=243

2004

Solberg1

hormone quantification

(none)

basal plasma corticosterone level [ng/mL] CORT0 15013

QTL population

both

not specified

N=243

2004

Solberg1

hormone quantification

(none)

plasma corticosterone response to a 10 min restraint stress [ng/mL] CORT10 15014

QTL population

both

not specified

N=243

2004

Solberg1

hormone quantification

(none)

insulin post-challenge [µU/mL] insulinpostglucchall 15021

QTL population

both

17wks

N=243

2004

Trullas1

hormone quantification

(none)

basal corticosterone levels (plasma) [µg/dL] cortico_basal 52851

inbred

5

m

6-8wks

N=4

1993

Trullas1

hormone quantification

(none)

stress-induced corticosterone levels (plasma) [µg/dL] cortico_stress 52852

inbred

5

m

6-8wks

N=4

1993

Trullas1

hormone quantification

(none)

fold change across cohorts in corticosterone levels (plasma) (stress to basal ratio) [ratio] cortico_ratio 52853

inbred

5

m

6-8wks

N=3

1993

Xenakis2

hormone quantification

arsenic

fasting plasma insulin (6h fast) [ng/mL] FPI 118380 iAs: 1 wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after

DO population

m

7-33wks

N=71

2022

Xenakis2

hormone quantification

arsenic

plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection [ng/mL] PI15 118387 iAs: 1 wk before 13 wks after 25 wks after

DO population

m

7-33wks

N=72

2022

Xenakis2

hormone quantification

arsenic

fasting plasma insulin (6h fast), coefficient of variation (CV) [%] FPI_CV 118390 iAs: 1wk before 4 wks after 8 wks after 13 wks after 16 wks after 20 wks after 25 wks after

DO population

m

7-33wks

N=73

2022

Xenakis2

hormone quantification

arsenic

plasma insulin, 15 min after intraperitoneal (i.p. 0.2% glucose, 6h fast) injection, coefficient of variation (CV) [%] PI15_CV 118397 iAs: 1wk before 13 wks after 25 wks after

DO population

m

7-33wks

N=72

2022

Yuan1

hormone quantification

(none)

insulin-like growth factor 1 (serum IGF-1) [ng/mL] IGF1 27001 6mo 12mo 18mo

inbred

33

both

N=7

2007

Zhang1

hormone quantification

western diet

plasma insulin [ng/mL] Insulin_mean 27944

QTL population

f

18wks

N=266

2012

Zhang1

hormone quantification

western diet

ln(insulin) Ln_insulin 27945

QTL population

f

18wks

N=266

2012

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