MPD: Phenotype measures mapped to MP:0005621, abnormal cell physiology

Phenotype measures associated with ontology term
MP:0005621 'abnormal cell physiology'

All measures in this list are mapped to the ontology descendants of MP:0005621. None are mapped to MP:0005621 directly.

MP:0000350 abnormal cell proliferation
MP:0001125 abnormal oocyte morphology
MP:0002674 abnormal sperm motility
MP:0003566 abnormal cell adhesion
MP:0008866 chromosomal instability
MP:0009340 abnormal splenocyte apoptosis
MP:0011439 abnormal kidney cell proliferation
MP:0020152 abnormal oocyte number
MP:0020414 abnormal fibroblast physiology

This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
CSNA03:685	CSNA03	in vitro assay	(none)	peak-to-peak interval, indicating amount of time it takes for one cycle of bioluminescence circadian rhythm, in fibroblast cultures, founders [h] period_in 112539	inbred w/CC8	8	both	8-12wks	N=9	2020

CSNA03:686	CSNA03	in vitro assay	(none)	peak-to-peak interval, indicating amount of time it takes for one cycle of bioluminescence circadian rhythm, in fibroblast cultures, CC [h] period_cc 112544	CC w/par	40	both	8-12wks	N=4	2020

CSNA03:688	CSNA03	in vitro assay	(none)	specific time point when bioluminescence reaches highest circadian rhythm amplitude (cycle number), in fibroblast cultures, founders [n] phase_in 112540	inbred w/CC8	8	both	8-12wks	N=9	2020

CSNA03:689	CSNA03	in vitro assay	(none)	specific time point when bioluminescence reaches highest circadian rhythm amplitude (cycle number), in fibroblast cultures, CC [n] phase_cc 112545	CC w/par	40	both	8-12wks	N=4	2020

CSNA03:691	CSNA03	in vitro assay	(none)	peak-to-trough, indicating level of synchronization in circadian rhythm (max counts/s), in fibroblast cultures, founders [n/s] amplitude_in 112541	inbred w/CC8	8	both	8-12wks	N=9	2020

CSNA03:692	CSNA03	in vitro assay	(none)	peak-to-trough, indicating level of synchronization in circadian rhythm (max counts/s), in fibroblast cultures, CC [n/s] amplitude_cc 112546	CC w/par	40	both	8-12wks	N=4	2020

CSNA03:694	CSNA03	in vitro assay	(none)	number of days required for circadian rhythm amplitude to decrease to 36% of initial value, in fibroblast cultures, founders [days] damping_in 112542	inbred w/CC8	8	both	8-12wks	N=9	2020

CSNA03:695	CSNA03	in vitro assay	(none)	number of days required for circadian rhythm amplitude to decrease to 36% of initial value, in fibroblast cultures, CC [days] damping_cc 112547	CC w/par	40	both	8-12wks	N=4	2020

CSNA03:697	CSNA03	in vitro assay	(none)	percentage of observed rhythms that fit expected sine wave, indicating stability and robustness of circadian rhythm, in fibroblast cultures, founders [%] goodness_of_fit_in 112543	inbred w/CC8	8	both	8-12wks	N=9	2020

CSNA03:698	CSNA03	in vitro assay	(none)	percentage of observed rhythms that fit expected sine wave, indicating stability and robustness of circadian rhythm, in fibroblast cultures, CC [%] goodness_of_fit_cc 112548	CC w/par	40	both	8-12wks	N=4	2020

Lazear1:3	Lazear1	microscopy	(none)	percentage of sperm that are motile [%] sperm_motile 63103	CC	10	m	15-22wks	N=2	2018

Lazear1:4	Lazear1	microscopy	(none)	percentage of sperm that move in a consistent direction [%] sperm_processive 63104	CC	10	m	15-22wks	N=2	2018

Mills1:5	Mills1	apoptosis assessment	(none)	early apoptotic splenocytes [%] early_apoptotic 25205 6mo 12mo 20mo	inbred	30	both		N=3	2008

Mills1:11	Mills1	apoptosis assessment	(none)	late apoptotic splenocytes [%] late_apoptotic 25211 6mo 12mo 20mo	inbred	30	both		N=3	2008

Mills1:17	Mills1	apoptosis assessment	(none)	all apoptotic splenocytes [%] all_apoptotic 25217 6mo 12mo 20mo	inbred	30	both		N=3	2008

Mills1:25	Mills1	chromosome instability assessment	(none)	reticulocytes with micronuclei [%] retic_micronucl 25225 6mo 12mo 20mo	inbred	30	both		N=5	2008

Mills1:31	Mills1	chromosome instability assessment	(none)	red blood cells (RBC) with micronuclei [%] RBC_micronucl 25231 6mo 12mo 20mo	inbred	30	both		N=5	2008

Mills1:35	Mills1	chromosome instability assessment	(none)	non-nucleated peripheral blood cells with micronuclei [%] all_micronucl 25235 6mo 12mo 20mo	inbred	30	both		N=5	2008

Odet2:8	Odet2	microscopy	(none)	percentage of sperm that are motile [%] sperm_motile 53808 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:15	Odet2	microscopy	(none)	percentage of motile sperm that are 'progressive' [%] sperm_prog 53815 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:21	Odet2	microscopy	(none)	percentage of motile sperm that are 'intermediate' [%] sperm_int 53821 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:28	Odet2	microscopy	(none)	percentage of motile sperm that are 'hyperactivated' [%] sperm_hyper 53828 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:35	Odet2	microscopy	(none)	percentage of motile sperm that are 'vigorous' [%] sperm_vigor 53835 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:41	Odet2	microscopy	(none)	percentage of motile sperm that are 'slow' [%] sperm_slow 53841 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:48	Odet2	microscopy	(none)	percentage of motile sperm that are 'weak' [%] sperm_weak 53848 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:55	Odet2	microscopy	(none)	sperm mean path velocity [µm/s] sperm_VAP 53855 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:61	Odet2	microscopy	(none)	sperm mean straight line velocity [µm/s] sperm_VSL 53861 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:68	Odet2	microscopy	(none)	sperm mean curvilinear velocity [µm/s] sperm_VCL 53868 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:75	Odet2	microscopy	(none)	sperm mean lateral head displacement (amplitude) [µm] sperm_ALH 53875 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:81	Odet2	microscopy	(none)	sperm mean cross beat frequency [Hz] sperm_BCF 53881 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:88	Odet2	microscopy	(none)	sperm mean straightness [ratio] sperm_STR 53888 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Odet2:94	Odet2	microscopy	(none)	sperm mean linearity [ratio] sperm_LIN 53894 min: 10 30 60 90 120	inbred w/CC8	8	m	10-66wks	N=13	2015

Parker1:1	Parker1	assisted reproduction	(none)	mean number of oocytes per female following treatment [n] oocyte_num 62901 2.5 IU eCG 5 IU eCG 5 + 5 IU eCG	inbred	6	f	3-6wks	N=18	2011

Parker1:4	Parker1	assisted reproduction	(none)	mean number of fertilized oocytes per female following treatment [n] oocyte_fert_num 62904 2.5 IU eCG 5 IU eCG 5 + 5 IU eCG	inbred	6	f	3-6wks	N=18	2011

Parker1:7	Parker1	assisted reproduction	(none)	percentage of oocytes that are fertilized per female following treatment [%] oocyte_fert_pct 62907 2.5 IU eCG 5 IU eCG 5 + 5 IU eCG	inbred	6	f	3-6wks	N=18	2011

Rusyn6:14	Rusyn6	histopathology	trichloroethylene	BrdU-positive nuclei in liver (hepatocellular proliferation), relative to control group [%] BrdU_liver_tce 51214	inbred	7	m	6-7wks	N=3	2014

Rusyn6:54	Rusyn6	histopathology	trichloroethylene	BrdU-positive nuclei in kidney (proximal tubule cell proliferation), relative to control group [%] BrdU_kidney_tce 51254	inbred	7	m	6-7wks	N=3	2014

Shorter4:14	Shorter4	microscopy	(none)	percentage of sperm that are motile [%] motile 110106 10 min 90 min	CC	12	m	15-33wks	N=3	2019

Shorter4:16	Shorter4	microscopy	(none)	percentage of motile sperm that are 'vigorous' [%] vigorous 110108 10 min 90 min	CC	12	m	15-33wks	N=3	2019

Shorter4:18	Shorter4	microscopy	(none)	percentage of motile sperm that are 'hyperactivated' [%] hyper 110110 10 min 90 min	CC	12	m	15-33wks	N=3	2019

Shorter4:20	Shorter4	microscopy	(none)	sperm mean curvilinear velocity [µm/s] VCL 110112 10 min 90 min	CC	12	m	15-33wks	N=3	2019

Shorter5:14	Shorter5	microscopy	(none)	percentage of sperm that are motile [%] motile 110147 10 min 90 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter5:16	Shorter5	microscopy	(none)	percentage of motile sperm that are 'vigorous' [%] vigorous 110149 10 min 90 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter5:18	Shorter5	microscopy	(none)	percentage of motile sperm that are 'hyperactivated' [%] hyper 110151 10 min 90 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter5:20	Shorter5	microscopy	(none)	sperm mean curvilinear velocity [µm/s] VCL 110153 10 min 90 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter6:1	Shorter6	microscopy	(none)	percentage of sperm that are motile [%] sperm_motile 65601 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:6	Shorter6	microscopy	(none)	percentage of motile sperm that are 'vigorous' [%] sperm_vigor 65606 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:11	Shorter6	microscopy	(none)	percentage of motile sperm that are 'progressive' [%] sperm_prog 65611 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:16	Shorter6	microscopy	(none)	percentage of motile sperm that are 'hyperactivated' [%] sperm_hyper 65616 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:21	Shorter6	microscopy	(none)	percentage of motile sperm that are 'intermediate' [%] sperm_int 65621 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:26	Shorter6	microscopy	(none)	percentage of motile sperm that are 'slow' [%] sperm_slow 65626 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:31	Shorter6	microscopy	(none)	percentage of motile sperm that are 'weak' [%] sperm_weak 65631 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:36	Shorter6	microscopy	(none)	sperm mean path velocity [µm/s] sperm_VAP 65636 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:41	Shorter6	microscopy	(none)	sperm mean straight line velocity [µm/s] sperm_VSL 65641 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:46	Shorter6	microscopy	(none)	sperm mean curvilinear velocity [µm/s] sperm_VCL 65646 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:51	Shorter6	microscopy	(none)	sperm mean lateral head displacement (amplitude) [µm] sperm_ALH 65651 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:56	Shorter6	microscopy	(none)	sperm mean cross beat frequency [Hz] sperm_BCF 65656 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:61	Shorter6	microscopy	(none)	sperm mean straightness [ratio] sperm_STR 65661 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter6:66	Shorter6	microscopy	(none)	sperm mean linearity [ratio] sperm_LIN 65666 10 min 30 min 60 min 90 min 120 min	CC	12	m	15-33wks	N=3	2019

Shorter7:1	Shorter7	microscopy	(none)	percentage of sperm that are motile [%] sperm_motile 65701 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:6	Shorter7	microscopy	(none)	percentage of motile sperm that are 'vigorous' [%] sperm_vigor 65706 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:11	Shorter7	microscopy	(none)	percentage of motile sperm that are 'progressive' [%] sperm_prog 65711 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:16	Shorter7	microscopy	(none)	percentage of motile sperm that are 'hyperactivated' [%] sperm_hyper 65716 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:21	Shorter7	microscopy	(none)	percentage of motile sperm that are 'intermediate' [%] sperm_int 65721 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:26	Shorter7	microscopy	(none)	percentage of motile sperm that are 'slow' [%] sperm_slow 65726 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:31	Shorter7	microscopy	(none)	percentage of motile sperm that are 'weak' [%] sperm_weak 65731 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:36	Shorter7	microscopy	(none)	sperm mean path velocity [µm/s] sperm_VAP 65736 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:41	Shorter7	microscopy	(none)	sperm mean straight line velocity [µm/s] sperm_VSL 65741 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:46	Shorter7	microscopy	(none)	sperm mean curvilinear velocity [µm/s] sperm_VCL 65746 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:51	Shorter7	microscopy	(none)	sperm mean lateral head displacement (amplitude) [µm] sperm_ALH 65751 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:56	Shorter7	microscopy	(none)	sperm mean cross beat frequency [Hz] sperm_BCF 65756 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:61	Shorter7	microscopy	(none)	sperm mean straightness [ratio] sperm_STR 65761 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter7:66	Shorter7	microscopy	(none)	sperm mean linearity [ratio] sperm_LIN 65766 10 min 30 min 60 min 90 min 120 min	CC RIX	28	m	7-44wks	N=4	2019

Shorter8:15	Shorter8	microscopy	(none)	percentage of sperm that are motile [%] sperm_motile 110170	DO population		m	12-15wks	N=150	2019

Shorter8:16	Shorter8	microscopy	(none)	percentage of motile sperm that are 'vigorous' [%] sperm_vigor 110171	DO population		m	12-15wks	N=149	2019

Shorter8:17	Shorter8	microscopy	(none)	percentage of motile sperm that are 'progressive' [%] sperm_prog 110172	DO population		m	12-15wks	N=149	2019

Shorter8:18	Shorter8	microscopy	(none)	percentage of motile sperm that are 'hyperactivated' [%] sperm_hyper 110173	DO population		m	12-15wks	N=149	2019

Shorter8:19	Shorter8	microscopy	(none)	percentage of motile sperm that are 'intermediate' [%] sperm_int 110174	DO population		m	12-15wks	N=149	2019

Shorter8:20	Shorter8	microscopy	(none)	percentage of motile sperm that are 'slow' [%] sperm_slow 110175	DO population		m	12-15wks	N=149	2019

Shorter8:21	Shorter8	microscopy	(none)	percentage of motile sperm that are 'weak' [%] sperm_weak 110176	DO population		m	12-15wks	N=149	2019

Shorter8:22	Shorter8	microscopy	(none)	sperm mean path velocity [µm/s] sperm_VAP 110177	DO population		m	12-15wks	N=149	2019

Shorter8:23	Shorter8	microscopy	(none)	sperm mean straight line velocity [µm/s] sperm_VSL 110178	DO population		m	12-15wks	N=149	2019

Shorter8:24	Shorter8	microscopy	(none)	sperm mean curvilinear velocity [µm/s] sperm_VCL 110179	DO population		m	12-15wks	N=149	2019

Shorter8:25	Shorter8	microscopy	(none)	sperm mean lateral head displacement (amplitude) [µm] sperm_ALH 110180	DO population		m	12-15wks	N=149	2019

Shorter8:26	Shorter8	microscopy	(none)	sperm mean cross beat frequency [Hz] sperm_BCF 110181	DO population		m	12-15wks	N=149	2019

Taft1:3	Taft1	assisted reproduction	(none)	total oocytes per donor [n] oocyte_donor 19303	inbred	10	f		N=17	2006

Taft1:5	Taft1	assisted reproduction	(none)	percent of live oocytes per donor [%] pct_live_super 19305	inbred	10	f		N=17	2006

Taft1:6	Taft1	assisted reproduction	(none)	percent of dead oocytes per donor [%] pct_dead_super 19306	inbred	10	f		N=17	2006

Taft1:7	Taft1	assisted reproduction	(none)	percent of fragmented oocytes per donor [%] pct_frag_super 19307	inbred	10	f		N=17	2006

Taft1:14	Taft1	assisted reproduction	(none)	fragmented oocytes, percentage of IVF dish cells [%] pct_frag_IVF 19314	inbred	10	f		N=17	2006

Yuan5:1	Yuan5	biomarker quantification	(none)	plasma levels of P-selectin [ng/mL] P-selectin 21101	QTL population		f	18wks	N=234	2008

Yuan5:2	Yuan5	biomarker quantification	(none)	plasma levels of soluble vascular cell adhesion molecule-1 [ng/mL] VCAM1 21102	QTL population		f	18wks	N=234	2008

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