MPD: Data set: Shorter4

Shorter4 downloads
• Download Shorter4 project data set animal data, as uploaded
• Download Shorter4 animal data matrix with factor-related expansion applied as necessary
• Download Shorter4 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Shorter4 measures:

MA:0000397 epididymis
MA:0000410 seminal vesicle
MA:0000411 testis
MA:0000413 vas deferens
MA:0002765 male germ cell
MP:0001259 abnormal body weight
MP:0002673 abnormal sperm number
MP:0002674 abnormal sperm motility
MP:0004850 abnormal testis weight
MP:0004908 abnormal seminal vesicle weight
MP:0004926 abnormal epididymis size
MP:0006362 abnormal male germ cell morphology
MP:0008892 abnormal sperm flagellum morphology
VT:0001259 body mass
VT:0001922 male fertility trait
VT:0002673 sperm quantity
VT:0002674 sperm motility trait
VT:0002997 seminal gland size trait
VT:0010019 epididymis mass
VT:0010042 sperm morphology trait
VT:1000644 testis mass

Investigators	John R Shorter University of North Carolina, Chapel Hill, NC Deborah A O'Brien University of North Carolina, Chapel Hill, NC Fernando Pardo-Manuel de Villena University of North Carolina, Chapel Hill, NC
Participants	Pan W, Odet F, Aylor DL, Kao C-Y, Fu C-P, Greenstein S, Bell TA, Stevans AM, Patel S, Cates SE, Shaw GD, MIller DR, McMillian L
Contact	Fernando Pardo-Manuel de Villena fernando@med.unc.edu Lab web site
Part of a series:	• Organ weights, sperm count and morphology (this project) Shorter4 • Sperm motility see Shorter6
Acknowledgements	Funding provided by NIH HD065024; Eunice Kennedy Shriver National Institute of Child Health and Human Development. We would like to thank Lisa Branstetter, T. Justin Gooch, Stephanie Hansen, Ginger Shaw, Jennifer Shockley and Jason Spence for mouse work.
Project type	Phenotype strain survey data set
MPD identifiers	Shorter4 MPD:654
Data changelog	No updates/corrections. Initial release date: 06/2020.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Male reproductive parameters were assessed. This project contains data for organ weights and sperm count, motility, and morphology while Shorter6 contains Computer Assisted Sperm Analysis (CASA) data.

Procedures conducted:

• body weight
• organ weights		Male reproductive organ weights. Testes, seminal vesicles, epididymis + vas deferens.
• sperm count		Sperm count. Hemocytometer.
• microscopy		Sperm motility
• histopathology		Male reproductive histopathology. Percent normal, abnormal sperm.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Shorter4:1	Shorter4	body weight	(none)	body weight [g] bw 110093	CC	12	m	15-33wks	N=3

Shorter4:2	Shorter4	organ weights	(none)	testis weight [g] testis 110094 left right	CC	12	m	15-33wks	N=3

Shorter4:4	Shorter4	organ weights	(none)	testis weight mean [g] testis_mean 110096	CC	12	m	15-33wks	N=3

Shorter4:5	Shorter4	organ weights	(none)	testis weight as a percentage of body weight [%] testis_pct_bw 110097	CC	12	m	15-33wks	N=3

Shorter4:6	Shorter4	organ weights	(none)	epididymis plus vas deferens weight [g] epidid_vd 110098 left right	CC	12	m	15-33wks	N=3

Shorter4:8	Shorter4	organ weights	(none)	epididymis plus vas deferens weight mean [g] epidid_vd_mean 110100	CC	12	m	15-33wks	N=3

Shorter4:9	Shorter4	organ weights	(none)	epididymis plus vas deferens weight as a percentage of body weight [%] epidid_vd_pct_bw 110101	CC	12	m	15-33wks	N=3

Shorter4:10	Shorter4	organ weights	(none)	seminal vesicles weight total [g] semin_vesi_tot 110102	CC	12	m	15-33wks	N=3

Shorter4:11	Shorter4	organ weights	(none)	seminal vesicles weight as a percentage of body weight [%] semin_vesi_pct_bw 110103	CC	12	m	15-33wks	N=3

Shorter4:12	Shorter4	sperm count	(none)	sperm count per mouse (x 10⁶) [n] sperm_count 110104	CC	12	m	15-33wks	N=3

Shorter4:13	Shorter4	sperm count	(none)	sperm count per mg testis weight (x 10³) [n/mg] sperm_adj 110105	CC	12	m	15-33wks	N=3

Shorter4:14	Shorter4	microscopy	(none)	percentage of sperm that are motile [%] motile 110106 10 min 90 min	CC	12	m	15-33wks	N=3

Shorter4:16	Shorter4	microscopy	(none)	percentage of motile sperm that are 'vigorous' [%] vigorous 110108 10 min 90 min	CC	12	m	15-33wks	N=3

Shorter4:18	Shorter4	microscopy	(none)	percentage of motile sperm that are 'hyperactivated' [%] hyper 110110 10 min 90 min	CC	12	m	15-33wks	N=3

Shorter4:20	Shorter4	microscopy	(none)	sperm mean curvilinear velocity [µm/s] VCL 110112 10 min 90 min	CC	12	m	15-33wks	N=3

Shorter4:22	Shorter4	histopathology	(none)	percentage of sperm with normal morphology [%] normal_sperm 110114	CC	12	m	15-33wks	N=3

Shorter4:23	Shorter4	histopathology	(none)	percentage of sperm with abnormal head shape [%] abnormal_head 110115	CC	12	m	15-33wks	N=3

Shorter4:24	Shorter4	histopathology	(none)	percentage of sperm with abnormal tail bending [%] abnormal_tail 110116	CC	12	m	15-33wks	N=3

Shorter4:25	Shorter4	histopathology	(none)	percentage of sperm with broken tails [%] broken_tail 110117	CC	12	m	15-33wks	N=3

Shorter4: Male reproduction in 12 Collaborative Cross strains of mice: Organ weights and sperm count, motility, and morphology (2020)

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