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Project measure / variable:   CSNA03   goodness_of_fit_in

ID, description, units MPD:112543   goodness_of_fit_in   percentage of observed rhythms that fit expected sine wave, indicating stability and robustness of circadian rhythm, in fibroblast cultures, founders   [%]  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age: 8-12wks
Procedure in vitro assay
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  STRAIN COMPARISON PLOT
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CSNA03 - percentage of observed rhythms that fit expected sine wave, indicating stability and robustness of circadian rhythm, in fibroblast cultures, founders



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means83.27   % 82.62   %
Median of the strain means82.06   % 81.86   %
SD of the strain means± 5.8902 ± 5.4182
Coefficient of variation (CV)0.0707 0.0656
Min–max range of strain means75.44   –   93.5   % 75.79   –   93.09   %
Mean sample size per strain9.4   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 14.3765 14.3765 0.3497 0.5553
strain 7 4006.4175 572.3454 13.9204 < 0.0001
sex:strain 7 300.5427 42.9347 1.0442 0.4036
Residuals 131 5386.1298 41.1155


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 82.51 8.2546   10 2.6103 0.1 73.29, 91.96 -0.13
129S1/SvImJ m 77.4 8.7219   9 2.9073 0.1127 67.56, 90.79 -0.96
A/J f 81.6 3.9118   9 1.3039 0.0479 73.19, 87.17 -0.28
A/J m 80.76 2.5547   9 0.85156 0.0316 77.39, 85.1 -0.34
C57BL/6J f 81.08 9.3688   10 2.9627 0.1156 66.49, 91.91 -0.37
C57BL/6J m 81.86 7.6814   10 2.4291 0.0938 64.21, 92.55 -0.14
CAST/EiJ f 93.5 1.6915   10 0.53491 0.0181 90.47, 95.28 1.74
CAST/EiJ m 93.09 1.8919   10 0.59828 0.0203 89.29, 94.58 1.93
NOD/ShiLtJ f 75.44 6.8848   9 2.2949 0.0913 68.38, 86.62 -1.33
NOD/ShiLtJ m 75.79 6.7901   9 2.2634 0.0896 65.95, 85.99 -1.26
NZO/HlLtJ f 84.02 6.7595   8 2.3899 0.0805 73.3, 93.86 0.13
NZO/HlLtJ m 81.86 4.777   7 1.8055 0.0584 74.05, 89.8 -0.14
PWK/PhJ f 89.81 2.1808   10 0.68962 0.0243 86.83, 93.49 1.11
PWK/PhJ m 86.68 4.2131   10 1.3323 0.0486 77.13, 90.94 0.75
WSB/EiJ f 78.23 11.02   9 3.6734 0.1409 65.38, 92.02 -0.86
WSB/EiJ m 83.56 5.7541   8 2.0344 0.0689 73.11, 90.29 0.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 82.513 2.0276956011 86.5242655839 78.5017344161
129S1/SvImJ m 77.3955555556 2.1373788336 81.6238007372 73.1673103739
A/J f 81.5977777778 2.1373788336 85.8260229594 77.3695325961
A/J m 80.7588888889 2.1373788336 84.9871340705 76.5306437073
C57BL/6J f 81.078 2.0276956011 85.0892655839 77.0667344161
C57BL/6J m 81.861 2.0276956011 85.8722655839 77.8497344161
CAST/EiJ f 93.501 2.0276956011 97.5122655839 89.4897344161
CAST/EiJ m 93.09 2.0276956011 97.1012655839 89.0787344161
NOD/ShiLtJ f 75.4433333333 2.1373788336 79.671578515 71.2150881517
NOD/ShiLtJ m 75.79 2.1373788336 80.0182451816 71.5617548184
NZO/HlLtJ f 84.02 2.2670326008 88.5047312607 79.5352687393
NZO/HlLtJ m 81.8557142857 2.4235597934 86.6500936712 77.0613349002
PWK/PhJ f 89.813 2.0276956011 93.8242655839 85.8017344161
PWK/PhJ m 86.678 2.0276956011 90.6892655839 82.6667344161
WSB/EiJ f 78.2344444444 2.1373788336 82.4626896261 74.0061992628
WSB/EiJ m 83.565 2.2670326008 88.0497312607 79.0802687393


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 79.9542777778 1.4730867022 82.8683946637 77.0401608918
A/J both 81.1783333333 1.5113550672 84.1681541738 78.1885124929
C57BL/6J both 81.4695 1.4337973097 84.3058930955 78.6331069045
CAST/EiJ both 93.2955 1.4337973097 96.1318930955 90.4591069045
NOD/ShiLtJ both 75.6166666667 1.5113550672 78.6064875071 72.6268458262
NZO/HlLtJ both 82.9378571429 1.6592979604 86.2203443162 79.6553699695
PWK/PhJ both 88.2455 1.4337973097 91.0818930955 85.4091069045
WSB/EiJ both 80.8997222222 1.557869145 83.9815590039 77.8178854405




  GWAS USING LINEAR MIXED MODELS