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Project measure / variable:   CSNA03   phase_cc

ID, description, units MPD:112545   phase_cc   specific time point when bioluminescence reaches highest circadian rhythm amplitude (cycle number), in fibroblast cultures, CC   [n]  
Data set, strains CSNA03   CC w/par   40 strains     sex: both     age: 8-12wks
Procedure in vitro assay
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  STRAIN COMPARISON PLOT
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CSNA03 - specific time point when bioluminescence reaches highest circadian rhythm amplitude (cycle number), in fibroblast cultures, CC



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested35 strains34 strains
Mean of the strain means6.6571   n 6.9033   n
Median of the strain means6.9264   n 7.2287   n
SD of the strain means± 2.8544 ± 2.5932
Coefficient of variation (CV)0.4288 0.3756
Min–max range of strain means0.822   –   12.986   n 2.0932   –   14.387   n
Mean sample size per strain3.9   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.5516 0.5516 0.2791 0.5979
strain 23 1265.8447 55.0367 27.8484 < 0.0001
sex:strain 23 84.6004 3.6783 1.8612 0.0127
Residuals 197 389.3311 1.9763


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.7396 0.86203   10 0.2726 0.3147 1.2015, 3.9857 -1.37
129S1/SvImJ m 3.2516 0.43862   9 0.14621 0.1349 2.7477, 4.07 -1.41
A/J f 3.883 1.5044   9 0.50148 0.3874 0.96967, 5.7873 -0.97
A/J m 4.1686 1.4181   10 0.44844 0.3402 2.1573, 6.211 -1.05
C57BL/6J f 4.4274 0.79374   10 0.251 0.1793 3.3537, 5.6963 -0.78
C57BL/6J m 3.4233 0.69286   10 0.2191 0.2024 2.5543, 4.4967 -1.34
CAST/EiJ f 1.978 0.90551   10 0.28635 0.4578 0.84725, 3.4713 -1.64
CAST/EiJ m 2.0932 0.83365   10 0.26362 0.3983 0.58775, 3.5928 -1.85
CC001/UncJ f 7.1742 0.46775   2   0.33075 0.0652 6.8435, 7.505 0.18
CC001/UncJ m 6.448 0.0   1   0.0 0.0 6.448, 6.448 -0.18
CC002/UncJ f 8.5446 0.72889   2   0.5154 0.0853 8.0292, 9.06 0.66
CC002/UncJ m 7.279 0.81034   2   0.573 0.1113 6.706, 7.852 0.14
CC003/UncJ f 0.822 0.0   1   0.0 0.0 0.822, 0.822 -2.04
CC004/TauUncJ f 4.2764 0.00190919   2   0.00135 0.0004 4.275, 4.2777 -0.83
CC004/TauUncJ m 3.8522 0.09907   2   0.07005 0.0257 3.7822, 3.9223 -1.18
CC005/TauUncJ f 6.4874 0.64597   4 0.32299 0.0996 5.9787, 7.416 -0.06
CC005/TauUncJ m 7.3549 1.1471   3 0.66227 0.156 6.598, 8.6747 0.17
CC008/GeniUncJ f 12.882 5.6965   2   4.028 0.4422 8.854, 16.91 2.18
CC008/GeniUncJ m 7.6521 2.0868   2   1.4756 0.2727 6.1765, 9.1277 0.29
CC010/GeniUncJ m 7.1785 0.34252   2   0.2422 0.0477 6.9363, 7.4207 0.11
CC011/UncJ f 6.6846 0.53206   3 0.30719 0.0796 6.2827, 7.288 0.01
CC011/UncJ m 7.6169 1.5877   6 0.64817 0.2084 6.1253, 10.056 0.28
CC012/GeniUncJ f 6.504 1.0356   5 0.46311 0.1592 5.103, 7.835 -0.05
CC012/GeniUncJ m 6.5697 1.2098   6 0.49388 0.1841 5.066, 8.504 -0.13
CC013/GeniUncJ f 9.131 2.6035   3 1.5031 0.2851 7.1175, 12.071 0.87
CC013/GeniUncJ m 6.0568 2.5735   2   1.8197 0.4249 4.237, 7.8765 -0.33
CC016/GeniUncJ f 5.9707 0.96202   2   0.68025 0.1611 5.2905, 6.651 -0.24
CC016/GeniUncJ m 6.8438 3.3469   2   2.3667 0.489 4.4772, 9.2105 -0.02
CC017/UncJ m 8.6697 0.78154   3 0.45122 0.0901 7.929, 9.4865 0.68
CC018/UncJ f 6.9264 1.0708   2   0.75715 0.1546 6.1692, 7.6835 0.09
CC018/UncJ m 6.5504 1.6418   3 0.94791 0.2506 4.6653, 7.667 -0.14
CC019/TauUncJ f 8.5897 4.4931   3 2.5941 0.5231 4.868, 13.581 0.68
CC019/TauUncJ m 9.0307 0.93656   2   0.66225 0.1037 8.3685, 9.693 0.82
CC023/GeniUncJ f 12.986 5.6798   2   4.0163 0.4374 8.9695, 17.002 2.22
CC023/GeniUncJ m 8.96 2.9387   2   2.078 0.328 6.882, 11.038 0.79
CC025/GeniUncJ f 8.7865 0.89608   5 0.40074 0.102 7.8982, 9.999 0.75
CC025/GeniUncJ m 8.5348 0.91862   4 0.45931 0.1076 7.5765, 9.3863 0.63
CC028/GeniUncJ f 6.5893 0.61485   3 0.35498 0.0933 6.1588, 7.2935 -0.02
CC028/GeniUncJ m 7.3352 0.90856   3 0.52456 0.1239 6.3945, 8.2078 0.17
CC030/GeniUncJ f 7.9677 0.67635   2   0.47825 0.0849 7.4895, 8.446 0.46
CC030/GeniUncJ m 9.061 0.0   1   0.0 0.0 9.061, 9.061 0.83
CC035/UncJ f 7.371 0.0   1   0.0 0.0 7.371, 7.371 0.25
CC037/TauUncJ f 8.9135 0.0   1   0.0 0.0 8.9135, 8.9135 0.79
CC041/TauUncJ f 7.2179 3.7383   4 1.8691 0.5179 3.877, 12.153 0.2
CC041/TauUncJ m 6.744 1.8013   6 0.73539 0.2671 4.4093, 8.9753 -0.06
CC043/GeniUncJ m 14.387 0.0   1   0.0 0.0 14.387, 14.387 2.89
CC051/TauUncJ f 9.611 0.0   1   0.0 0.0 9.611, 9.611 1.03
CC051/TauUncJ m 10.412 0.0   1   0.0 0.0 10.412, 10.412 1.35
CC057/UncJ f 8.066 0.0   1   0.0 0.0 8.066, 8.066 0.49
CC059/TauUncJ f 8.5634 1.9662   4 0.98309 0.2296 6.6275, 10.949 0.67
CC061/GeniUncJ f 9.736 0.0   1   0.0 0.0 9.736, 9.736 1.08
CC061/GeniUncJ m 8.0702 0.54129   2   0.38275 0.0671 7.6875, 8.453 0.45
CC068/TauUncJ f 6.703 0.0   1   0.0 0.0 6.703, 6.703 0.02
CC074/UncJ m 9.7048 0.0   1   0.0 0.0 9.7048, 9.7048 1.08
CC075/UncJ f 5.6845 0.07849   2   0.0555 0.0138 5.629, 5.74 -0.34
CC075/UncJ m 6.2358 0.26042   3 0.15036 0.0418 5.96, 6.4775 -0.26
CC078/TauUncJ m 9.516 0.0   1   0.0 0.0 9.516, 9.516 1.01
CC080/TauUncJ f 7.174 0.0   1   0.0 0.0 7.174, 7.174 0.18
CC080/TauUncJ m 7.382 0.0   1   0.0 0.0 7.382, 7.382 0.18
CC084/TauJ f 8.5802 0.96202   2   0.68025 0.1121 7.9, 9.2605 0.67
CC084/TauJ m 9.5648 2.4073   2   1.7022 0.2517 7.8625, 11.267 1.03
NOD/ShiLtJ f 3.2399 1.0086   9 0.33619 0.3113 2.178, 4.787 -1.2
NOD/ShiLtJ m 3.3653 0.86256   10 0.27276 0.2563 1.3388, 4.36 -1.36
NZO/HlLtJ f 2.8196 1.0878   8 0.3846 0.3858 0.78933, 3.886 -1.34
NZO/HlLtJ m 3.0046 1.2124   7 0.45825 0.4035 1.1, 4.1555 -1.5
PWK/PhJ f 2.9007 0.47471   10 0.15012 0.1637 1.9387, 3.524 -1.32
PWK/PhJ m 4.2627 1.2099   10 0.3826 0.2838 2.3375, 5.7205 -1.02
WSB/EiJ f 3.0683 1.026   9 0.34201 0.3344 1.4805, 4.7633 -1.26
WSB/EiJ m 4.1313 0.83626   8 0.29566 0.2024 3.0187, 5.1455 -1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.73964 0.4445559645 3.6163394969 1.8629405031
129S1/SvImJ m 3.2516111111 0.4686031317 4.1757335223 2.3274886999
A/J f 3.8830077778 0.4686031317 4.807130189 2.9588853666
A/J m 4.16859 0.4445559645 5.0452894969 3.2918905031
C57BL/6J f 4.42744 0.4445559645 5.3041394969 3.5507405031
C57BL/6J m 3.42326 0.4445559645 4.2999594969 2.5465605031
CAST/EiJ f 1.978005 0.4445559645 2.8547044969 1.1013055031
CAST/EiJ m 2.093185 0.4445559645 2.9698844969 1.2164855031
CC002/UncJ f 8.5446 0.9940573564 10.5049596709 6.5842403291
CC002/UncJ m 7.279 0.9940573564 9.2393596709 5.3186403291
CC004/TauUncJ f 4.27635 0.9940573564 6.2367096709 2.3159903291
CC004/TauUncJ m 3.85225 0.9940573564 5.8126096709 1.8918903291
CC005/TauUncJ f 6.487375 0.7029046976 7.8735586168 5.1011913832
CC005/TauUncJ m 7.3549 0.8116444327 8.9555269686 5.7542730314
CC008/GeniUncJ f 12.882 0.9940573564 14.8423596709 10.9216403291
CC008/GeniUncJ m 7.6521 0.9940573564 9.6124596709 5.6917403291
CC011/UncJ f 6.6846333333 0.8116444327 8.285260302 5.0840063647
CC011/UncJ m 7.61685 0.5739192823 8.7486641837 6.4850358163
CC012/GeniUncJ f 6.504 0.6286970742 7.7438403186 5.2641596814
CC012/GeniUncJ m 6.56965 0.5739192823 7.7014641837 5.4378358163
CC013/GeniUncJ f 9.131 0.8116444327 10.7316269686 7.5303730314
CC013/GeniUncJ m 6.05675 0.9940573564 8.0171096709 4.0963903291
CC016/GeniUncJ f 5.97075 0.9940573564 7.9311096709 4.0103903291
CC016/GeniUncJ m 6.84385 0.9940573564 8.8042096709 4.8834903291
CC018/UncJ f 6.92635 0.9940573564 8.8867096709 4.9659903291
CC018/UncJ m 6.5504333333 0.8116444327 8.151060302 4.9498063647
CC019/TauUncJ f 8.5896666667 0.8116444327 10.1902936353 6.989039698
CC019/TauUncJ m 9.03075 0.9940573564 10.9911096709 7.0703903291
CC023/GeniUncJ f 12.98575 0.9940573564 14.9461096709 11.0253903291
CC023/GeniUncJ m 8.96 0.9940573564 10.9203596709 6.9996403291
CC025/GeniUncJ f 8.78654 0.6286970742 10.0263803186 7.5466996814
CC025/GeniUncJ m 8.534825 0.7029046976 9.9210086168 7.1486413832
CC028/GeniUncJ f 6.5893333333 0.8116444327 8.189960302 4.9887063647
CC028/GeniUncJ m 7.3351666667 0.8116444327 8.9357936353 5.734539698
CC041/TauUncJ f 7.2179 0.7029046976 8.6040836168 5.8317163832
CC041/TauUncJ m 6.7439666667 0.5739192823 7.8757808503 5.612152483
CC075/UncJ f 5.6845 0.9940573564 7.6448596709 3.7241403291
CC075/UncJ m 6.2357666667 0.8116444327 7.8363936353 4.635139698
CC084/TauJ f 8.58025 0.9940573564 10.5406096709 6.6198903291
CC084/TauJ m 9.56475 0.9940573564 11.5251096709 7.6043903291
NOD/ShiLtJ f 3.2398888889 0.4686031317 4.1640113001 2.3157664777
NOD/ShiLtJ m 3.36534 0.4445559645 4.2420394969 2.4886405031
NZO/HlLtJ f 2.81955375 0.4970286782 3.7997335854 1.8393739146
NZO/HlLtJ m 3.0046 0.5313460072 4.0524563205 1.9567436795
PWK/PhJ f 2.90068 0.4445559645 3.7773794969 2.0239805031
PWK/PhJ m 4.26271 0.4445559645 5.1394094969 3.3860105031
WSB/EiJ f 3.0683222222 0.4686031317 3.9924446334 2.144199811
WSB/EiJ m 4.13125 0.4970286782 5.1114298354 3.1510701646


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.9956255556 0.3229624206 3.632532974 2.3587181371
A/J both 4.0257988889 0.3229624206 4.6627063073 3.3888914704
C57BL/6J both 3.92535 0.3143485371 4.5452701593 3.3054298407
CAST/EiJ both 2.035595 0.3143485371 2.6555151593 1.4156748407
CC002/UncJ both 7.9118 0.7029046976 9.2979836168 6.5256163832
CC004/TauUncJ both 4.0643 0.7029046976 5.4504836168 2.6781163832
CC005/TauUncJ both 6.9211375 0.5368523305 7.9798527252 5.8624222748
CC008/GeniUncJ both 10.26705 0.7029046976 11.6532336168 8.8808663832
CC011/UncJ both 7.1507416667 0.4970286782 8.1309215021 6.1705618312
CC012/GeniUncJ both 6.536825 0.4256299313 7.3762008637 5.6974491363
CC013/GeniUncJ both 7.593875 0.6416612644 8.8592817263 6.3284682737
CC016/GeniUncJ both 6.4073 0.7029046976 7.7934836168 5.0211163832
CC018/UncJ both 6.7383916667 0.6416612644 8.003798393 5.4729849404
CC019/TauUncJ both 8.8102083333 0.6416612644 10.0756150596 7.544801607
CC023/GeniUncJ both 10.972875 0.7029046976 12.3590586168 9.5866913832
CC025/GeniUncJ both 8.6606825 0.4715228056 9.590562739 7.730802261
CC028/GeniUncJ both 6.96225 0.5739192823 8.0940641837 5.8304358163
CC041/TauUncJ both 6.9809333333 0.4537230313 7.8757110105 6.0861556562
CC075/UncJ both 5.9601333333 0.6416612644 7.2255400596 4.694726607
CC084/TauJ both 9.0725 0.7029046976 10.4586836168 7.6863163832
NOD/ShiLtJ both 3.3026144444 0.3229624206 3.9395218629 2.665707026
NZO/HlLtJ both 2.912076875 0.3637877425 3.6294950547 2.1946586953
PWK/PhJ both 3.581695 0.3143485371 4.2016151593 2.9617748407
WSB/EiJ both 3.5997861111 0.3415502899 4.2733502767 2.9262219455




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA