|
|
open field test
|
Locomotor, exploratory, and anxiety-related behavior. 20 min test some at 5 min intervals. |
inbred w/CC8
|
both |
8-9wks |
2020 |
|
|
grip strength
|
Several trials. |
inbred w/CC8
|
both |
8-10wks |
2020 |
|
|
observation (SHIRPA)
|
Behavior, and neurosensory responses (SHIRPA protocol). |
inbred w/CC8
|
both |
8-10wks |
2020 |
|
|
rotarod
|
Latency to fall from accelerating rotarod. |
inbred w/CC7
|
both |
9-10wks |
2020 |
|
|
acoustic startle test
|
Acoustic startle response, prepulse inhibition. |
inbred w/CC8
|
both |
9-10wks |
2020 |
|
|
metabolic panel
|
Glucose, glycerol. 16h fast. |
inbred
|
both |
10-11wks |
2020 |
|
|
lipid profile
|
Cholesterol, HDL, non-HDL, triglycerides, fatty acids. 16h fast, plasma. |
inbred
|
both |
10-11wks |
2020 |
|
|
nociception assay
|
Hot plate (two trials). |
inbred w/CC8
|
both |
11-12wks |
2020 |
|
|
transepidermal water loss test
|
Transepidermal water loss in condenser chamber. |
inbred w/CC8
|
both |
11-12wks |
2020 |
|
|
monitoring system
|
Locomotor activity and energy metabolism. 21h test. |
inbred w/CC8
|
both |
12-13wks |
2020 |
|
|
intake monitoring
|
Food, water intake. 21h test. |
inbred w/CC8
|
both |
12-13wks |
2020 |
|
|
NMR
|
Body mass, fat and lean tissue mass. |
inbred w/CC8
|
both |
12-13, 18-19wks |
2020 |
|
|
glucose tolerance
|
0 to 120 min after 20% glucose i.p., 16h fast. |
inbred w/CC8
|
both |
13-14wks |
2020 |
|
|
echocardiography
|
Cardiovascular function and morphology. |
inbred w/CC8
|
both |
14-15wks |
2020 |
|
|
ECG
|
Heart rate and wave intervals. Conscious. |
inbred
|
both |
14-15wks |
2020 |
|
|
organ dimensions
|
Axial length of eye. |
inbred w/CC8
|
both |
14-17wks |
2020 |
|
|
Scheimpflug imaging
|
Eye lens density. |
inbred w/CC8
|
both |
14-17wks |
2020 |
|
|
computed tomography
|
Retinal thickness and fundus vessels. |
inbred w/CC8
|
both |
14-17wks |
2020 |
|
|
virtual optomotor
|
Threshold of spatial frequency. |
inbred w/CC8
|
both |
14-17wks |
2020 |
|
|
complete blood count
|
Hematology. |
inbred w/CC8
|
both |
20-21wks |
2020 |
|
|
metabolic panel
|
Clinical blood chemistry (plasma). No fast. |
inbred w/CC8
|
both |
16-17, 20-21wks |
2020 |
|
|
lipid profile
|
Cholesterol, triglycerides. No fast, plasma. |
inbred w/CC8
|
both |
16-17, 20-21wks |
2020 |
|
|
ABR test
|
Auditory brainstem response. |
inbred w/CC7
|
both |
17-18wks |
2020 |
|
|
body size and weight
|
Body weight and length. |
inbred w/CC8
|
both |
17-18wks |
2020 |
|
|
DXA
|
Body mass, fat mass, lean mass, bone mineral density and content, bone area. |
inbred w/CC8
|
both |
17-18wks |
2020 |
|
|
X-ray
|
Lumbar vertebrae count. |
inbred w/CC8
|
both |
17-18wks |
2020 |
|
|
ventilator
|
Lung, respiratory function. |
inbred w/CC8
|
f |
21-22wks |
2020 |
|
|
immunoglobulin quantification
|
Immunoglobulins (plasma). |
inbred w/CC8
|
both |
16-17, 20-21wks |
2020 |
|
|
autoantibody quantification
|
Anti-DNA autoantibodies, rheumatoid factor. |
inbred w/CC8
|
both |
16-17, 20-21wks |
2020 |
|
|
bone dimensions
|
Tibia bone length. |
inbred w/CC8
|
both |
20-21wks |
2020 |
|
|
organ weights
|
Heart, liver, spleen weights. |
inbred w/CC8
|
both |
20-21wks |
2020 |
|
|
body weight
|
Body weight and growth curve from 8wks to 21wks. |
inbred w/CC8
|
both |
8-21wks |
2020 |