MPD: Data set: GMC16

Kollmus H, Fuchs H, Lengger C, Haselimashhadi H, Bogue MA, Östereicher MA, Horsch M, Adler T, Aguilar-Pimentel JA, Amarie OV, Becker L, Beckers J, Calzada-Wack J, Garrett L, Hans W, Hölter SM, Klein-Rodewald T, Maier H, Mayer-Kuckuk P, Miller G, Moreth K, Neff F, Rathkolb B, Rácz I, Rozman J, Spielmann N, Treise I, Busch D, Graw J, Klopstock T, Wolf E, Wurst W, Yildirim AÖ, Mason J, Torres A, Mouse Phenome Database Team., Balling R, Mehaan T, Gailus-Durner V, Schughart K, Hrabě de Angelis M. A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes. Mamm Genome. 2020 Feb;31(1-2):30-48. doi: 10.1007/s00335-020-09827-3. Epub 2020 Feb 14. PubMed 32060626 FullText

GMC16 downloads
• Download GMC16 project data set animal data, as uploaded
• Download GMC16 animal data matrix with factor-related expansion applied as necessary
• Download GMC16 strain means, SD, N, etc. one row per strain/sex/measure
• GMC16 supplementary data

Ontology terms mapped to GMC16 measures:

Institutional authorship	German Mouse Clinic and Department of Infection Genetics, HZI Lab web site
Investigators	GMC Management Team German Mouse Clinic, Neuherberg GERMANY
Participants	Hrabě de Angelis M, Fuchs H, Gailus-Durner V, Rathkolb B, Wolf E, Lengger C, Kollmus H, Schughart K
Contact	GMC Management Team coregmc@helmholtz-muenchen.de Lab web site
Affiliated Center	German Mouse Clinic (GMC)
Acknowledgements	Funding provided by German Ministry of Education and Research (Infrafrontier Grant 01KX1012) to GMC and by intramural grants from the Helmholtz Association (Program Infection and Immunity) to KS
Project type	Phenotype strain survey data set
MPD identifiers	GMC16 MPD:565
Data changelog	No updates/corrections. Initial release date: 02/2020.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Experimental groups in this study:
• None • None • None • None

Procedures conducted:

• metabolic panel		Clinical blood chemistry (plasma). No fast.
• lipid profile		Cholesterol, triglycerides. No fast, plasma.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Sample Size (Avg)
GMC16:1	GMC16	body weight	(none)	body weight [g] bw 56501 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:10	GMC16	metabolic panel	(none)	calcium (plasma Ca) [mmol/L] calcium 56510 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:12	GMC16	metabolic panel	(none)	chloride (plasma Cl) [mmol/L] chloride 56512 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:14	GMC16	metabolic panel	(none)	iron (plasma Fe) [µmol/L] iron 56514 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:16	GMC16	metabolic panel	(none)	unsaturated iron binding capacity (plasma UIBC) [µmol/L] iron_binding_21 56516	inbred w/CC8	6	both	N=3

GMC16:18	GMC16	metabolic panel	(none)	lactate (plasma) [mmol/L] lactate 56518 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:20	GMC16	metabolic panel	(none)	phosphorus (plasma phosphate) [mmol/L] phosphate 56520 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:22	GMC16	metabolic panel	(none)	potassium (plasma K) [mmol/L] potassium 56522 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=6

GMC16:24	GMC16	metabolic panel	(none)	sodium (plasma Na) [mmol/L] sodium 56524 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=6

GMC16:26	GMC16	metabolic panel	(none)	alkaline phosphatase (plasma ALP) [IU/L] ALP 56526 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:28	GMC16	metabolic panel	(none)	alanine transaminase (plasma ALT) [IU/L] ALT 56528 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:30	GMC16	metabolic panel	(none)	aspartate transaminase (plasma AST) [IU/L] AST 56530 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=6

GMC16:32	GMC16	metabolic panel	(none)	lactic acid dehydrogenase (plasma LDH) [IU/L] LDH 56532 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=6

GMC16:34	GMC16	metabolic panel	(none)	alpha-amylase (plasma) [IU/L] amylase 56534 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:36	GMC16	metabolic panel	(none)	glucose (plasma GLU) [mmol/L] GLU 56536 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:38	GMC16	metabolic panel	(none)	albumin (plasma Alb) [g/L] albumin 56538 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:40	GMC16	metabolic panel	(none)	creatinine (plasma) [µmol/L] creatinine 56540 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:42	GMC16	metabolic panel	(none)	total protein (plasma TP) [g/L] total_protein 56542 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:44	GMC16	metabolic panel	(none)	blood urea nitrogen (plasma BUN) [mmol/L] urea 56544 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:46	GMC16	lipid profile	(none)	total cholesterol (plasma CHOL) [mmol/L] CHOL 56546 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16:48	GMC16	lipid profile	(none)	triglyceride (plasma TG) [mmol/L] TG 56548 age 16-17wks 20-21wks	inbred w/CC8	8	both	N=7

GMC16: Clinical blood chemistry for 8 inbred founder strains of the Collaborative Cross (2020)