MPD: Measures involving fear conditioning test

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Bolivar2:1	Bolivar2	fear conditioning test	(none)	activity (beam breaks) during 2.5 min period of training on day 1 [n] act_shock 63901 before shock after 1st shock after 2nd shock after 3rd shock	inbred	8	both	9-20wks	N=18	2001

Bolivar2:5	Bolivar2	fear conditioning test	(none)	percentage of baseline activity that occurred after third shock of training period [%] act_shock3_pct 63905	inbred	8	both	9-20wks	N=18	2001

Bolivar2:6	Bolivar2	fear conditioning test	(none)	activity (beam breaks) during 1 min period of contextual conditioning on day 2 [n] act_context 63906 1st min 2nd min 3rd min 4th min 5th min mean	inbred	8	both	9-20wks	N=18	2001

Bolivar2:12	Bolivar2	fear conditioning test	(none)	percentage of baseline activity that occurred after contextual conditioning [%] act_context_pct 63912	inbred	8	both	9-20wks	N=18	2001

Bolivar2:13	Bolivar2	fear conditioning test	(none)	activity (beam breaks) during 1 min period of altered context on day 2 [n] act_altered 63913 1st min 2nd min 3rd min mean	inbred	8	both	9-20wks	N=18	2001

Bolivar2:17	Bolivar2	fear conditioning test	(none)	activity (beam breaks) during 1 min period of cued conditioning on day 2 [n] act_cued 63917 1st min 2nd min 3rd min mean	inbred	8	both	9-20wks	N=18	2001

Bolivar2:21	Bolivar2	fear conditioning test	(none)	percentage of altered context activity that occurred after cued conditioning [%] act_cued_pct 63921	inbred	8	both	9-20wks	N=18	2001

Gould2:17	Gould2	fear conditioning test	nicotine	acute group, percent immobility in training chamber after first stimulus pairing [%] FC_immediate_acu 47131 dose (mg): control 0.045 0.09 0.18	inbred	8	m	8-12wks	N=11	2011

Gould2:21	Gould2	fear conditioning test	nicotine	acute group, percent immobility in training chamber, 24h after fear conditioning [%] FC_context_acu 47136 dose (mg): control 0.045 0.09 0.18	inbred	8	m	8-12wks	N=11	2011

Gould2:25	Gould2	fear conditioning test	nicotine	acute group, percent immobility in altered context chamber, pre-cue [%] FC_preCS_acu 47141 dose (mg): control 0.045 0.09 0.18	inbred	8	m	8-12wks	N=11	2011

Gould2:29	Gould2	fear conditioning test	nicotine	acute group, percent immobility in altered context chamber, cue [%] FC_CS_acu 47146 dose (mg) control 0.045 0.09 0.18	inbred	8	m	8-12wks	N=11	2011

Gould2:33	Gould2	fear conditioning test	nicotine	chronic group, conditioning: immediate fear [%] FC_immediate_chr 47151 control nicotine	inbred	8	m	8-12wks	N=10	2011

Gould2:35	Gould2	fear conditioning test	nicotine	chronic group, conditioning: contextual fear [%] FC_context_chr 47156 control nicotine	inbred	8	m	8-12wks	N=10	2011

Gould2:37	Gould2	fear conditioning test	nicotine	chronic group, cued fear: pre-cue [%] FC_preCS_chr 47161 control nicotine	inbred	8	m	8-12wks	N=10	2011

Gould2:39	Gould2	fear conditioning test	nicotine	chronic group, cued fear: cue [%] FC_CS_chr 47166 control nicotine	inbred	8	m	8-12wks	N=10	2011

Gould3:41	Gould3	fear conditioning test	nicotine	withdrawal study group, percent immobility in training chamber after first stimulus pairing [%] FC_immediate 47341 control nicotine dose (mg) 3 6.3 12	inbred	8	m	8-12wks	N=12	2011

Gould3:46	Gould3	fear conditioning test	nicotine	withdrawal study group, percent immobility in training chamber, 24h after fear conditioning [%] FC_context 47346 control nicotine dose (mg) 3 6.3 12	inbred	8	m	8-12wks	N=12	2011

Gould3:61	Gould3	fear conditioning test	nicotine	withdrawal study group, percent immobility in altered context chamber, pre-cue [%] FC_preCS 47361 control nicotine dose (mg) 3 6.3 12	inbred	8	m	8-12wks	N=12	2011

Gould3:66	Gould3	fear conditioning test	nicotine	withdrawal study group, percent immobility in altered context chamber, cue [%] FC_CS 47366 control nicotine dose (mg) 3 6.3 12	inbred	8	m	8-12wks	N=12	2011

HMDPpheno4:1	HMDPpheno4	fear conditioning test	(none)	fear training, percent time spent near chamber walls, day1 [%] ftr_thig 46801 pre-stimulus post-stimulus	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:11	HMDPpheno4	fear conditioning test	(none)	fear training, velocity, day 1 [cm/s] ftr_vel 46811 pre-stimulus post-stimulus	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:21	HMDPpheno4	fear conditioning test	(none)	fear training, percent time immobile, day 1 [%] ftr_imob 46821 pre-stimulus post-stimulus	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:31	HMDPpheno4	fear conditioning test	(none)	fear training activity burst to footshock, shock reactivity, day 1 [cm/s] ftr_post_act_burst 46831	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:36	HMDPpheno4	fear conditioning test	(none)	contextual fear thigmotaxis, percent time spent near chamber walls, day 2 [%] ctx_thig 46836	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:41	HMDPpheno4	fear conditioning test	(none)	contextual fear velocity, day 2 [cm/s] ctx_vel 46841	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:46	HMDPpheno4	fear conditioning test	(none)	contextual fear percent time immobile, day 2 [%] ctx_imob 46846	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:51	HMDPpheno4	fear conditioning test	(none)	cued fear thigmotaxis, percent time spent near chamber walls, day 3 [%] thig 46851 pre-cue cue	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:61	HMDPpheno4	fear conditioning test	(none)	cued fear, velocity, day 3 [cm/s] vel 46861 pre-cue cue	HMDP w/par	94	m	10wks	N=7	2011

HMDPpheno4:71	HMDPpheno4	fear conditioning test	(none)	cued fear, percent time immobile, day 3 [%] imob 46871 pre-cue cue	HMDP w/par	94	m	10wks	N=7	2011

Mooney2:2	Mooney2	fear conditioning test	nicotine	percent freezing during the initial 2 min of training [%] baseline 110079 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10	2019

Mooney2:5	Mooney2	fear conditioning test	nicotine	percent freezing during the 2 min period inbetween CS-US exposures [%] immediate 110082 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10	2019

Mooney2:8	Mooney2	fear conditioning test	nicotine	percent freezing during a context testing trial [%] context 110085 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10	2019

Mooney2:11	Mooney2	fear conditioning test	nicotine	percent freezing during a 3 min PreCS exposure in a novel context [%] precs 110088 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10	2019

Mooney2:14	Mooney2	fear conditioning test	nicotine	percent freezing during a 3 min CS exposure in a novel context [%] cs 110091 mg/kg/day: 0 12 18	inbred	21	m	8-12wks	N=10	2019

Neuner1:62	Neuner1	fear conditioning test	(none)	percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning [%] cfc_6mo 65962 baseline 1st shock 2nd shock 3rd shock 4th shock	F1 AD-BXD	50	both	23-25wks	N=3	2019

Neuner1:67	Neuner1	fear conditioning test	(none)	percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning [%] cfc_14mo 65967 baseline 1st shock 2nd shock 3rd shock 4th shock	F1 AD-BXD	51	both	55-57wks	N=4	2019

Neuner1:72	Neuner1	fear conditioning test	(none)	change in percentage of time spent freezing from 1st post-shock to 4th post-shock (slope), day 1 contextual fear acquisition cfa_change 65972 6 mo 14 mo	F1 AD-BXD	55	both	23-57wks	N=3	2019

Neuner1:74	Neuner1	fear conditioning test	(none)	percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test [%] cfm_6mo 65974 1st 2 min 2nd 2 min 3rd 2 min 4th 2 min 5th 2 min total	F1 AD-BXD	50	both	23-25wks	N=3	2019

Neuner1:80	Neuner1	fear conditioning test	(none)	percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test [%] cfm_14mo 65980 1st 2 min 2nd 2 min 3rd 2 min 4th 2 min 5th 2 min total	F1 AD-BXD	51	both	55-57wks	N=4	2019

Palmer1:1	Palmer1	fear conditioning test	(none)	time freezing before exposure to shock, from 30-180 s, day 1 [s] pretraining_freezing 25501	B6.A consomic w/par	19	both	7-12wks	N=12	2007

Palmer1:3	Palmer1	fear conditioning test	(none)	time freezing in context with 24h history and exposure to shock, from 30-180s, day 2 [s] freezing_to_context 25503	B6.A consomic w/par	19	both	7-12wks	N=12	2007

Palmer1:4	Palmer1	fear conditioning test	(none)	time freezing in altered context (no tone) with 48h history and exposure to shock, from 30-180s, day 3 [s] freezing_altered 25504	B6.A consomic w/par	19	both	7-12wks	N=12	2007

Palmer1:5	Palmer1	fear conditioning test	(none)	time freezing in altered context during 30 s in between 2 tones, day 3 [s] freezing_btw_tones 25505	B6.A consomic w/par	19	both	7-12wks	N=12	2007

Palmer1:6	Palmer1	fear conditioning test	(none)	average time freezing during two 30 s tones in altered context, day 3 [s] freezing_to_tones 25506	B6.A consomic w/par	19	both	7-12wks	N=12	2007

Palmer3:21	Palmer3	fear conditioning test	(none)	percentage of time freezing during tone presentation on day 1 [%] d1_tone 59221	F1 Tcf7l2	30	both	7-14wks	N=5	2017

Palmer3:22	Palmer3	fear conditioning test	(none)	percentage of time freezing to context on day 2 [%] d2_context 59222	F1 Tcf7l2	30	both	7-14wks	N=5	2017

Palmer3:23	Palmer3	fear conditioning test	(none)	percentage of time freezing to tone on day 3 [%] d3_tone 59223	F1 Tcf7l2	30	both	7-14wks	N=5	2017

Palmer5:21	Palmer5	fear conditioning test	(none)	percentage of time freezing during tone presentation on day 1 [%] d1_tone 59721	F1 Tcf7l2	30	both	7-14wks	N=5	2017

Palmer5:22	Palmer5	fear conditioning test	(none)	percentage of time freezing to context on day 2 [%] d2_context 59722	F1 Tcf7l2	30	both	7-14wks	N=5	2017

Palmer5:23	Palmer5	fear conditioning test	(none)	percentage of time freezing to tone on day 3 [%] d3_tone 59723	F1 Tcf7l2	30	both	7-14wks	N=5	2017

Project1061:1	Project1061	fear conditioning test	(none)	cohort cohort 113862 measure and covariate nicotine saline	BXD w/par	31	both		N=8	2021

Project1061:5	Project1061	fear conditioning test	(none)	baseline [%] baseline 113866 nicotine saline	BXD w/par	31	both		N=8	2021

Project1061:7	Project1061	fear conditioning test	(none)	immediate [%] immediate 113868 nicotine saline	BXD w/par	31	both		N=8	2021

Project1061:9	Project1061	fear conditioning test	(none)	context [%] context 113870 nicotine saline	BXD w/par	31	both		N=8	2021

Project1061:11	Project1061	fear conditioning test	(none)	precs [%] precs 113872 nicotine saline	BXD w/par	31	both		N=8	2021

Project1061:13	Project1061	fear conditioning test	(none)	cs [%] cs 113874 nicotine saline	BXD w/par	31	both		N=8	2021

Shin1:3	Shin1	fear conditioning test	(none)	percent time freezing during 5 min of contextual exposure [%] FC_memory 54503	inbred	11	m	12-14wks	N=10	2016

Bolivar2

fear conditioning test

(none)

activity (beam breaks) during 2.5 min period of training on day 1 [n] act_shock 63901 before shock after 1st shock after 2nd shock after 3rd shock

inbred

8

both

9-20wks

N=18

2001

Bolivar2

fear conditioning test

(none)

percentage of baseline activity that occurred after third shock of training period [%] act_shock3_pct 63905

inbred

8

both

9-20wks

N=18

2001

Bolivar2

fear conditioning test

(none)

activity (beam breaks) during 1 min period of contextual conditioning on day 2 [n] act_context 63906 1st min 2nd min 3rd min 4th min 5th min mean

inbred

8

both

9-20wks

N=18

2001

Bolivar2

fear conditioning test

(none)

percentage of baseline activity that occurred after contextual conditioning [%] act_context_pct 63912

inbred

8

both

9-20wks

N=18

2001

Bolivar2

fear conditioning test

(none)

activity (beam breaks) during 1 min period of altered context on day 2 [n] act_altered 63913 1st min 2nd min 3rd min mean

inbred

8

both

9-20wks

N=18

2001

Bolivar2

fear conditioning test

(none)

activity (beam breaks) during 1 min period of cued conditioning on day 2 [n] act_cued 63917 1st min 2nd min 3rd min mean

inbred

8

both

9-20wks

N=18

2001

Bolivar2

fear conditioning test

(none)

percentage of altered context activity that occurred after cued conditioning [%] act_cued_pct 63921

inbred

8

both

9-20wks

N=18

2001

Gould2

fear conditioning test

nicotine

acute group, percent immobility in training chamber after first stimulus pairing [%] FC_immediate_acu 47131 dose (mg): control 0.045 0.09 0.18

inbred

8

m

8-12wks

N=11

2011

Gould2

fear conditioning test

nicotine

acute group, percent immobility in training chamber, 24h after fear conditioning [%] FC_context_acu 47136 dose (mg): control 0.045 0.09 0.18

inbred

8

m

8-12wks

N=11

2011

Gould2

fear conditioning test

nicotine

acute group, percent immobility in altered context chamber, pre-cue [%] FC_preCS_acu 47141 dose (mg): control 0.045 0.09 0.18

inbred

8

m

8-12wks

N=11

2011

Gould2

fear conditioning test

nicotine

acute group, percent immobility in altered context chamber, cue [%] FC_CS_acu 47146 dose (mg) control 0.045 0.09 0.18

inbred

8

m

8-12wks

N=11

2011

Gould2

fear conditioning test

nicotine

chronic group, conditioning: immediate fear [%] FC_immediate_chr 47151 control nicotine

inbred

8

m

8-12wks

N=10

2011

Gould2

fear conditioning test

nicotine

chronic group, conditioning: contextual fear [%] FC_context_chr 47156 control nicotine

inbred

8

m

8-12wks

N=10

2011

Gould2

fear conditioning test

nicotine

chronic group, cued fear: pre-cue [%] FC_preCS_chr 47161 control nicotine

inbred

8

m

8-12wks

N=10

2011

Gould2

fear conditioning test

nicotine

chronic group, cued fear: cue [%] FC_CS_chr 47166 control nicotine

inbred

8

m

8-12wks

N=10

2011

Gould3

fear conditioning test

nicotine

withdrawal study group, percent immobility in training chamber after first stimulus pairing [%] FC_immediate 47341 control nicotine dose (mg) 3 6.3 12

inbred

8

m

8-12wks

N=12

2011

Gould3

fear conditioning test

nicotine

withdrawal study group, percent immobility in training chamber, 24h after fear conditioning [%] FC_context 47346 control nicotine dose (mg) 3 6.3 12

inbred

8

m

8-12wks

N=12

2011

Gould3

fear conditioning test

nicotine

withdrawal study group, percent immobility in altered context chamber, pre-cue [%] FC_preCS 47361 control nicotine dose (mg) 3 6.3 12

inbred

8

m

8-12wks

N=12

2011

Gould3

fear conditioning test

nicotine

withdrawal study group, percent immobility in altered context chamber, cue [%] FC_CS 47366 control nicotine dose (mg) 3 6.3 12

inbred

8

m

8-12wks

N=12

2011

HMDPpheno4

fear conditioning test

(none)

fear training, percent time spent near chamber walls, day1 [%] ftr_thig 46801 pre-stimulus post-stimulus

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

fear training, velocity, day 1 [cm/s] ftr_vel 46811 pre-stimulus post-stimulus

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

fear training, percent time immobile, day 1 [%] ftr_imob 46821 pre-stimulus post-stimulus

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

fear training activity burst to footshock, shock reactivity, day 1 [cm/s] ftr_post_act_burst 46831

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

contextual fear thigmotaxis, percent time spent near chamber walls, day 2 [%] ctx_thig 46836

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

contextual fear velocity, day 2 [cm/s] ctx_vel 46841

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

contextual fear percent time immobile, day 2 [%] ctx_imob 46846

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

cued fear thigmotaxis, percent time spent near chamber walls, day 3 [%] thig 46851 pre-cue cue

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

cued fear, velocity, day 3 [cm/s] vel 46861 pre-cue cue

HMDP w/par

94

m

10wks

N=7

2011

HMDPpheno4

fear conditioning test

(none)

cued fear, percent time immobile, day 3 [%] imob 46871 pre-cue cue

HMDP w/par

94

m

10wks

N=7

2011

Mooney2

fear conditioning test

nicotine

percent freezing during the initial 2 min of training [%] baseline 110079 mg/kg/day: 0 12 18

inbred

21

m

8-12wks

N=10

2019

Mooney2

fear conditioning test

nicotine

percent freezing during the 2 min period inbetween CS-US exposures [%] immediate 110082 mg/kg/day: 0 12 18

inbred

21

m

8-12wks

N=10

2019

Mooney2

fear conditioning test

nicotine

percent freezing during a context testing trial [%] context 110085 mg/kg/day: 0 12 18

inbred

21

m

8-12wks

N=10

2019

Mooney2

fear conditioning test

nicotine

percent freezing during a 3 min PreCS exposure in a novel context [%] precs 110088 mg/kg/day: 0 12 18

inbred

21

m

8-12wks

N=10

2019

Mooney2

fear conditioning test

nicotine

percent freezing during a 3 min CS exposure in a novel context [%] cs 110091 mg/kg/day: 0 12 18

inbred

21

m

8-12wks

N=10

2019

Neuner1

fear conditioning test

(none)

percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning [%] cfc_6mo 65962 baseline 1st shock 2nd shock 3rd shock 4th shock

F1 AD-BXD

50

both

23-25wks

N=3

2019

Neuner1

fear conditioning test

(none)

percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning [%] cfc_14mo 65967 baseline 1st shock 2nd shock 3rd shock 4th shock

F1 AD-BXD

51

both

55-57wks

N=4

2019

Neuner1

fear conditioning test

(none)

change in percentage of time spent freezing from 1st post-shock to 4th post-shock (slope), day 1 contextual fear acquisition cfa_change 65972 6 mo 14 mo

F1 AD-BXD

55

both

23-57wks

N=3

2019

Neuner1

fear conditioning test

(none)

percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test [%] cfm_6mo 65974 1st 2 min 2nd 2 min 3rd 2 min 4th 2 min 5th 2 min total

F1 AD-BXD

50

both

23-25wks

N=3

2019

Neuner1

fear conditioning test

(none)

percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test [%] cfm_14mo 65980 1st 2 min 2nd 2 min 3rd 2 min 4th 2 min 5th 2 min total

F1 AD-BXD

51

both

55-57wks

N=4

2019

Palmer1

fear conditioning test

(none)

time freezing before exposure to shock, from 30-180 s, day 1 [s] pretraining_freezing 25501

B6.A consomic w/par

19

both

7-12wks

N=12

2007

Palmer1

fear conditioning test

(none)

time freezing in context with 24h history and exposure to shock, from 30-180s, day 2 [s] freezing_to_context 25503

B6.A consomic w/par

19

both

7-12wks

N=12

2007

Palmer1

fear conditioning test

(none)

time freezing in altered context (no tone) with 48h history and exposure to shock, from 30-180s, day 3 [s] freezing_altered 25504

B6.A consomic w/par

19

both

7-12wks

N=12

2007

Palmer1

fear conditioning test

(none)

time freezing in altered context during 30 s in between 2 tones, day 3 [s] freezing_btw_tones 25505

B6.A consomic w/par

19

both

7-12wks

N=12

2007

Palmer1

fear conditioning test

(none)

average time freezing during two 30 s tones in altered context, day 3 [s] freezing_to_tones 25506

B6.A consomic w/par

19

both

7-12wks

N=12

2007

Palmer3

fear conditioning test

(none)

percentage of time freezing during tone presentation on day 1 [%] d1_tone 59221

F1 Tcf7l2

30

both

7-14wks

N=5

2017

Palmer3

fear conditioning test

(none)

percentage of time freezing to context on day 2 [%] d2_context 59222

F1 Tcf7l2

30

both

7-14wks

N=5

2017

Palmer3

fear conditioning test

(none)

percentage of time freezing to tone on day 3 [%] d3_tone 59223

F1 Tcf7l2

30

both

7-14wks

N=5

2017

Palmer5

fear conditioning test

(none)

percentage of time freezing during tone presentation on day 1 [%] d1_tone 59721

F1 Tcf7l2

30

both

7-14wks

N=5

2017

Palmer5

fear conditioning test

(none)

percentage of time freezing to context on day 2 [%] d2_context 59722

F1 Tcf7l2

30

both

7-14wks

N=5

2017

Palmer5

fear conditioning test

(none)

percentage of time freezing to tone on day 3 [%] d3_tone 59723

F1 Tcf7l2

30

both

7-14wks

N=5

2017

Project1061

fear conditioning test

(none)

cohort cohort 113862 measure and covariate nicotine saline

BXD w/par

31

both

N=8

2021

Project1061

fear conditioning test

(none)

baseline [%] baseline 113866 nicotine saline

BXD w/par

31

both

N=8

2021

Project1061

fear conditioning test

(none)

immediate [%] immediate 113868 nicotine saline

BXD w/par

31

both

N=8

2021

Project1061

fear conditioning test

(none)

context [%] context 113870 nicotine saline

BXD w/par

31

both

N=8

2021

Project1061

fear conditioning test

(none)

precs [%] precs 113872 nicotine saline

BXD w/par

31

both

N=8

2021

Project1061

fear conditioning test

(none)

cs [%] cs 113874 nicotine saline

BXD w/par

31

both

N=8

2021

Shin1

fear conditioning test

(none)

percent time freezing during 5 min of contextual exposure [%] FC_memory 54503

inbred

11

m

12-14wks

N=10

2016

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