Project measure / variable:   Palmer1   freezing_to_context

ID, description, units MPD:25503   freezing_to_context   time freezing in context with 24h history and exposure to shock, from 30-180s, day 2   [s]  
Data set, strains Palmer1   B6.A consomic w/par   19 strains     sex: both     age: 7-12wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Palmer1 - time freezing in context with 24h history and exposure to shock, from 30-180s, day 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested19 strains18 strains
Mean of the strain means24.6   s 21.3   s
Median of the strain means22.2   s 18.6   s
SD of the strain means± 10.7 ± 11.7
Coefficient of variation (CV)0.433 0.548
Min–max range of strain means8.92   –   47.3   s 3.95   –   49.1   s
Mean sample size per strain10.8   mice 11.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 646.5391 646.5391 2.8211 0.0938
strain 17 42501.8787 2500.1105 10.9091 < 0.0001
sex:strain 17 3571.4828 210.0872 0.9167 0.5543
Residuals 416 95337.2075 229.176


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 47.3 21.4   7 8.08 0.452 16.7, 73.1 2.12
A/J m 49.1 16.0   10 5.05 0.325 19.0, 74.0 2.38
B6.A-Chr1 f 25.1 14.2   8 5.03 0.567 2.67, 43.1 0.04
B6.A-Chr1 m 24.1 14.1   11 4.24 0.583 4.09, 53.7 0.24
B6.A-Chr10 f 41.7 19.0   11 5.73 0.455 18.9, 89.5 1.6
B6.A-Chr10 m 33.1 14.2   14 3.78 0.428 6.76, 51.8 1.01
B6.A-Chr11 f 30.5 21.8   11 6.58 0.716 4.46, 82.2 0.55
B6.A-Chr11 m 34.1 25.1   13 6.97 0.736 9.43, 81.1 1.09
B6.A-Chr12 f 15.9 13.5   12 3.9 0.851 1.96, 40.9 -0.82
B6.A-Chr12 m 17.1 16.0   9 5.33 0.934 3.02, 53.0 -0.36
B6.A-Chr14 f 9.51 7.44   11 2.24 0.783 -1.42
B6.A-Chr14 m 10.1 9.87   11 2.97 0.972 -1.25, 33.1 -0.96
B6.A-Chr15 f 12.8 11.0   7 4.15 0.857 1.24, 29.4 -1.11
B6.A-Chr15 m 13.4 9.62   6 3.93 0.716 -0.68
B6.A-Chr16 f 24.8 13.0   10 4.12 0.525 1.95, 44.7 0.02
B6.A-Chr17 f 20.6 10.0   12 2.89 0.485 5.33, 38.8 -0.38
B6.A-Chr17 m 21.0 16.1   11 4.85 0.765 4.62, 57.6 -0.03
B6.A-Chr18 f 34.3 21.8   12 6.3 0.636 1.42, 77.9 0.9
B6.A-Chr18 m 35.7 18.9   11 5.69 0.528 -1.6, 63.2 1.23
B6.A-Chr19 f 22.2 16.8   13 4.67 0.757 4.98, 50.2 -0.23
B6.A-Chr19 m 20.4 22.6   12 6.52 1.11 1.78, 85.4 -0.08
B6.A-Chr3 f 19.3 21.2   9 7.08 1.1 -3.21, 63.0 -0.5
B6.A-Chr3 m 3.95 2.62   9 0.874 0.663 -0.71, 6.94 -1.49
B6.A-Chr4 f 17.1 16.4   7 6.19 0.957 3.74, 48.6 -0.71
B6.A-Chr4 m 18.5 11.9   11 3.6 0.644 0.53, 34.7 -0.24
B6.A-Chr5 f 31.6 18.1   10 5.72 0.574 6.4, 66.5 0.65
B6.A-Chr5 m 15.8 12.3   13 3.42 0.781 -0.71, 39.5 -0.47
B6.A-Chr6 f 37.0 12.7   9 4.23 0.343 11.6, 56.0 1.16
B6.A-Chr6 m 33.2 19.2   13 5.31 0.576 8.36, 71.7 1.02
B6.A-Chr7 f 8.92 5.34   13 1.48 0.599 -0.89, 20.5 -1.47
B6.A-Chr7 m 5.47 5.65   13 1.57 1.03 -1.6, 18.3 -1.36
B6.A-Chr9 f 31.3 21.1   14 5.64 0.674 6.58, 73.5 0.62
B6.A-Chr9 m 16.3 10.1   12 2.91 0.617 6.05, 35.9 -0.43
B6.A-ChrX f 16.6 11.9   14 3.19 0.721 -0.35, 43.4 -0.75
B6.A-ChrX m 13.6 15.2   11 4.58 1.12 -1.24, 42.5 -0.66
C57BL/6J f 21.6 10.5   44 1.58 0.485 3.2, 49.8 -0.28
C57BL/6J m 18.8 13.2   38 2.14 0.699 -1.96, 48.6 -0.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 47.2857 5.7218 58.533 36.0384
A/J m 49.1 4.7872 58.5102 39.6898
B6.A-Chr1 f 25.0962 5.3523 35.6172 14.5753
B6.A-Chr1 m 24.1227 4.5644 33.095 15.1505
B6.A-Chr10 f 41.7455 4.5644 50.7177 32.7732
B6.A-Chr10 m 33.1043 4.046 41.0573 25.1512
B6.A-Chr11 f 30.5145 4.5644 39.4868 21.5423
B6.A-Chr11 m 34.1338 4.1987 42.3871 25.8806
B6.A-Chr12 f 15.89 4.3701 24.4803 7.2997
B6.A-Chr12 m 17.1378 5.0462 27.057 7.2186
B6.A-Chr14 f 9.5082 4.5644 18.4804 0.5359
B6.A-Chr14 m 10.1482 4.5644 19.1204 1.1759
B6.A-Chr15 f 12.8014 5.7218 24.0487 1.5541
B6.A-Chr15 m 13.435 6.1803 25.5835 1.2865
B6.A-Chr17 f 20.615 4.3701 29.2053 12.0247
B6.A-Chr17 m 21.0409 4.5644 30.0132 12.0687
B6.A-Chr18 f 34.3067 4.3701 42.8969 25.7164
B6.A-Chr18 m 35.7182 4.5644 44.6904 26.7459
B6.A-Chr19 f 22.2223 4.1987 30.4756 13.969
B6.A-Chr19 m 20.3775 4.3701 28.9678 11.7872
B6.A-Chr3 f 19.3156 5.0462 29.2348 9.3964
B6.A-Chr3 m 3.9544 5.0462 13.8736 0.0
B6.A-Chr4 f 17.1014 5.7218 28.3487 5.8541
B6.A-Chr4 m 18.5418 4.5644 27.5141 9.5696
B6.A-Chr5 f 31.56 4.7872 40.9702 22.1498
B6.A-Chr5 m 15.7777 4.1987 24.031 7.5244
B6.A-Chr6 f 37.0222 5.0462 46.9414 27.103
B6.A-Chr6 m 33.22 4.1987 41.4733 24.9667
B6.A-Chr7 f 8.9246 4.1987 17.1779 0.6713
B6.A-Chr7 m 5.4723 4.1987 13.7256 0.0
B6.A-Chr9 f 31.3 4.046 39.2531 23.3469
B6.A-Chr9 m 16.3425 4.3701 24.9328 7.7522
B6.A-ChrX f 16.5786 4.046 24.5316 8.6255
B6.A-ChrX m 13.6227 4.5644 22.595 4.6505
C57BL/6J f 21.6034 2.2822 26.0895 17.1173
C57BL/6J m 18.8445 2.4558 23.6718 14.0172


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 48.1929 3.7302 55.5252 40.8605
B6.A-Chr1 both 24.6095 3.5171 31.5231 17.6959
B6.A-Chr10 both 37.4249 3.0497 43.4197 31.43
B6.A-Chr11 both 32.3242 3.1009 38.4196 26.2287
B6.A-Chr12 both 16.5139 3.3377 23.0748 9.953
B6.A-Chr14 both 9.8282 3.2276 16.1725 3.4838
B6.A-Chr15 both 13.1182 4.2112 21.396 4.8404
B6.A-Chr17 both 20.828 3.1596 27.0387 14.6172
B6.A-Chr18 both 35.0124 3.1596 41.2232 28.8017
B6.A-Chr19 both 21.2999 3.0301 27.2562 15.3436
B6.A-Chr3 both 11.635 3.5682 18.6489 4.6211
B6.A-Chr4 both 17.8216 3.6597 25.0154 10.6278
B6.A-Chr5 both 23.6688 3.1838 29.9272 17.4105
B6.A-Chr6 both 35.1211 3.2823 41.573 28.6692
B6.A-Chr7 both 7.1985 2.9689 13.0344 1.3625
B6.A-Chr9 both 23.8213 2.9777 29.6745 17.968
B6.A-ChrX both 15.1006 3.0497 21.0955 9.1058
C57BL/6J both 20.2239 1.6763 23.519 16.9289




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA