MPD: Project measures / variables set: Graham1 CD4

Project measures / variables set: Graham1 CD4_brain

ID, description, units	MPD:63329 CD4_brain percentage of CD3+ T cells that are CD4+ in brain, post infection [%] West Nile virus study
Measures	• day 7 • day 12 • day 21 • day 28
Data set, strains	Graham1 CC RIX 5 strains sex: m age: 8-10wks
Procedure	immune cell quantification
Comparison	timecourse but different cohorts
Ontology mappings	VT:0010439 response to viral infection trait VT:0008073 CD4-positive T cell quantity MA:0000168 brain MP:0020185 altered susceptibility to viral infection MP:0008073 abnormal CD4-positive, alpha beta T cell number

Values Means Δ Means Z-scores

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Graham1 - percentage of CD3+ T cells that are CD4+ in brain, post infection

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	3	502.5694	167.5231	1.2389	0.3175
strain	2	162.3445	81.1722	0.6003	0.5567
group:strain	6	3408.0115	568.0019	4.2007	0.005
Residuals	24	3245.1987	135.2166

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Graham1	63329	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD4+ in brain, post infection [%] day 7 CD4_brain_d7	CC RIX	5	m	8-10wks
Graham1	63330	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD4+ in brain, post infection [%] day 12 CD4_brain_d12	CC RIX	5	m	8-10wks
Graham1	63331	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD4+ in brain, post infection [%] day 21 CD4_brain_d21	CC RIX	4	m	8-10wks
Graham1	63332	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD4+ in brain, post infection [%] day 28 CD4_brain_d28	CC RIX	5	m	8-10wks