Project measures / variables set:   Threadgill2   APAP_Sulf_50

ID, description, units MPD:39616   APAP_Sulf_50   serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]  
acetaminophen study
Measures
• baseline    • 0.5h    • 1h    • 2h    • 3h    • 6h
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Comparisontimecourse, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Threadgill2 - serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen



  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   strain 4 26.8599 6.715 1.086 0.3985
between   Residuals 15 92.7523 6.1835
within   group 5 365.5031 73.1006 36.7 < 0.0001
within   group:strain 20 60.8091 3.0405 1.5265 0.0974
within   Residuals 75 149.3883 1.9918

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested		SexAge
Threadgill2 39616 drug and metabolite quantification acetaminophen serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]   baseline  APAP_Sulf_50_0 inbred 5 m 6-8wks
Threadgill2 39617 drug and metabolite quantification acetaminophen serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]   0.5h  APAP_Sulf_50_0.5 inbred 5 m 6-8wks
Threadgill2 39618 drug and metabolite quantification acetaminophen serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]   1h  APAP_Sulf_50_1 inbred 5 m 6-8wks
Threadgill2 39619 drug and metabolite quantification acetaminophen serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]   2h  APAP_Sulf_50_2 inbred 5 m 6-8wks
Threadgill2 39620 drug and metabolite quantification acetaminophen serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]   3h  APAP_Sulf_50_3 inbred 5 m 6-8wks
Threadgill2 39621 drug and metabolite quantification acetaminophen serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]   6h  APAP_Sulf_50_6 inbred 5 m 6-8wks



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