Project measure / variable:   Threadgill2   APAP_Sulf_50_6

ID, description, units MPD:39621   APAP_Sulf_50_6   serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]  6h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen 6h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means2.21   µg/mL
Median of the strain means2.23   µg/mL
SD of the strain means± 0.638
Coefficient of variation (CV)0.288
Min–max range of strain means1.25   –   2.91   µg/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 7.6346 1.9087 1.733 0.1892
Residuals 17 18.7229 1.1013


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 2.91 1.48   4 0.738 0.507 1.61, 5.01 1.09
C57BL/6J m 2.23 1.2   4 0.601 0.538 1.01, 3.42 0.03
DBA/2J m 2.64 1.28   5 0.571 0.483 0.63, 4.12 0.67
LP/J m 1.25 0.397   5 0.178 0.318 0.72, 1.77 -1.51
NZW/LacJ m 2.04 0.487   4 0.243 0.239 1.33, 2.42 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 2.9125 0.5247 4.0196 1.8054
C57BL/6J m 2.235 0.5247 3.3421 1.1279
DBA/2J m 2.644 0.4693 3.6342 1.6538
LP/J m 1.25 0.4693 2.2402 0.2598
NZW/LacJ m 2.04 0.5247 3.1471 0.9329




  GWAS USING LINEAR MIXED MODELS