MPD: Project measures / variables set: Jentsch2 infusions

Project measures / variables set: Jentsch2 infusions_FR5

ID, description, units	MPD:49723 infusions_FR5 Fixed ratio 5 - self administration: number of infusions earned [n] cocaine study
Measures	• day 1 • day 3 • day 5
Data set, strains	Jentsch2 BXD 4 strains sex: both age: 8-17wks
Procedure	operant conditioning chamber
Comparison	repeated measures, set of trials, same cohort
Ontology mappings	VT:0002063 learning/memory/conditioning trait VT:0010473 impulsivity behavior trait VT:0010531 operant conditioning behavior trait VT:0010718 response to cocaine trait MP:0001988 cocaine preference MP:0002803 abnormal operant conditioning behavior MP:0010698 abnormal impulsive behavior control MP:0020158 abnormal behavioral response to cocaine

Values Means Δ Means Z-scores

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Jentsch2 - Fixed ratio 5 - self administration: number of infusions earned

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	290.5988	290.5988	2.279	0.1485
between strain	1	3774.1781	3774.1781	29.5984	< 0.0001
between sex:strain	1	35.8096	35.8096	0.2808	0.6026
between Residuals	18	2295.2317	127.5129
within group	2	280.0909	140.0455	4.6703	0.0157
within group:sex	2	10.9917	5.4959	0.1833	0.8333
within group:strain	2	606.1135	303.0568	10.1065	0.0003
within group:sex:strain	2	5.2927	2.6464	0.0883	0.9157
within Residuals	36	1079.5111	29.9864

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Jentsch2	49723	operant conditioning chamber	cocaine	Fixed ratio 5 - self administration: number of infusions earned [n] day 1 infusions1_FR5	BXD	4	both	8-17wks
Jentsch2	49724	operant conditioning chamber	cocaine	Fixed ratio 5 - self administration: number of infusions earned [n] day 3 infusions3_FR5	BXD	4	both	8-17wks
Jentsch2	49725	operant conditioning chamber	cocaine	Fixed ratio 5 - self administration: number of infusions earned [n] day 5 infusions5_FR5	BXD	4	both	8-17wks