Project measure / variable:   Jentsch2   infusions5_FR5

ID, description, units MPD:49725   infusions5_FR5   Fixed ratio 5 - self administration: number of infusions earned   [n]  day 5  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 5 - self administration: number of infusions earned day 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means37.5   n 35.0   n
Median of the strain means37.5   n 35.9   n
SD of the strain means± 17.7 ± 21.1
Coefficient of variation (CV)0.474 0.603
Min–max range of strain means24.9   –   50.0   n 9.43   –   58.7   n
Mean sample size per strain4.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 125.7813 125.7813 2.5565 0.1272
strain 1 3086.0114 3086.0114 62.7221 < 0.0001
sex:strain 1 25.3563 25.3563 0.5154 0.482
Residuals 18 885.6238 49.2013


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 9.43 9.31   7 3.52 0.987 1.0, 25.0 -1.21
BXD38/TyJ f 24.9 6.31   7 2.38 0.254 17.0, 32.0 -0.71
BXD38/TyJ m 28.3 7.56   10 2.39 0.267 15.0, 39.0 -0.32
BXD42/TyJ m 43.4 9.29   9 3.1 0.214 35.0, 65.0 0.4
BXD68/RwwJ f 50.0 8.49   2   6.0 0.17 44.0, 56.0 0.71
BXD68/RwwJ m 58.7 5.51   3 3.18 0.0939 55.0, 65.0 1.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 24.8571 2.6512 30.4271 19.2872
BXD38/TyJ m 28.3 2.2181 32.9601 23.6399
BXD68/RwwJ f 50.0 4.9599 60.4204 39.5796
BXD68/RwwJ m 58.6667 4.0497 67.1749 50.1585


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 26.5786 1.7284 30.2097 22.9474
BXD68/RwwJ both 54.3333 3.2016 61.0597 47.607




GWAS analysis not available: SNP data is not available for enough strains (at least 4)