Project measure / variable:   Jentsch2   infusions1_FR5

ID, description, units MPD:49723   infusions1_FR5   Fixed ratio 5 - self administration: number of infusions earned   [n]  day 1  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 5 - self administration: number of infusions earned day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means29.3   n 29.1   n
Median of the strain means29.3   n 31.0   n
SD of the strain means± 7.35 ± 11.6
Coefficient of variation (CV)0.251 0.399
Min–max range of strain means24.1   –   34.5   n 14.0   –   40.3   n
Mean sample size per strain4.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 50.9106 50.9106 0.756 0.396
strain 1 608.7716 608.7716 9.0402 0.0076
sex:strain 1 12.5576 12.5576 0.1865 0.671
Residuals 18 1212.1238 67.3402


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 14.0 12.2   7 4.6 0.87 2.0, 31.0 -1.3
BXD38/TyJ f 24.1 7.34   7 2.77 0.304 17.0, 37.0 -0.71
BXD38/TyJ m 26.3 9.21   10 2.91 0.35 13.0, 38.0 -0.24
BXD42/TyJ m 35.6 5.96   9 1.99 0.168 28.0, 48.0 0.56
BXD68/RwwJ f 34.5 9.19   2   6.5 0.266 28.0, 41.0 0.71
BXD68/RwwJ m 40.3 4.51   3 2.6 0.112 36.0, 45.0 0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 24.1429 3.1016 30.6591 17.6266
BXD38/TyJ m 26.3 2.595 31.7519 20.8481
BXD68/RwwJ f 34.5 5.8026 46.6908 22.3092
BXD68/RwwJ m 40.3333 4.7378 50.2871 30.3796


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 25.2214 2.022 29.4695 20.9733
BXD68/RwwJ both 37.4167 3.7456 45.2858 29.5475




GWAS analysis not available: SNP data is not available for enough strains (at least 4)