Xenakis2 animal documentation

Effects of inorganic arsenic exposure on body composition and type 2 diabetes indicators in Diversity Outbred (DO) male mice   (2022)

Xenakis JG, Fry R, Stýblo M, Pardo-Manuel de Villena F
With: Douillet C, Bell TA, Hock P, Farrington J, Liu T, Murphy CEY, Saraswatula A, Shaw GD, Nativio G, Shi Q, Venkatratnam A, Zou F




Animal Documentation

Source of Mice: The Jackson Laboratory

Age (wks): 4 wks of age at shipping

Breeding: DO generation 35 is used in the study

Feed: Semi-purified AIN-93G diet (Envigo Teklad, Madison, WI, USA), during acclimatization

Water: Arsenic-free deionized water (DIW) ad libitum, during acclimatization

Cage Density: One per cage

Temperature (°C): 22 +/- 1

Humidity (%): 50 +/- 10

Light / Dark Cycle: 12:12h

Health Status and Monitoring: The mouse sample GUDA_1007 was euthanized on 9-4-19 before completion of the study.

Care and Use Statement: All procedures involving mice were approved by the University of North Carolina Institutional Animal Care and Use Committee.