Morgan1 animal documentation

Drug study: Effects of olanzapine on body weight in 9 inbred strains of mice   (2014)

Morgan AP, Crowley JJ, Sullivan PF
With: Nonneman RJ, Quackenbush CR, Miller CN, Ryan AK, Bogue MA, Paredes SH, Yourstone S, Carroll IM, Kawula TH, Bower MA, Sartor RB




Morgan1 Animal Documentation

Acclimation & testing periods

Vendor

The Jackson Laboratory (JAX®, Bar Harbor, ME)

Ages
Tested at 8-18 wks of age
Feed

Standard chow (Purina Prolab RMH3000, 14 kcal% fat) until 8 wks of age; high-fat food given 8-18 wks of age, D09092903 (Research Diets, New Brunswick NJ, 45 kcal% fat), with or without olanzapine. All food given ad libitum throughout experiment.

Water
Provided ad libitum
Temperature
20-24°C
Humidity
40-50%
Housing
Housed 4 per cage; standard 20 cm x 30 cm ventilated polysulfone cages with Bed-O-Cob bedding
Photoperiod 14:10h light-dark cycle
Care and Use

Protocols approved by the Institutional Animal Care and Use Committee of the University of North Carolina at Chapel Hill