ITP2018 compounds

Interventions Testing Program: Lifespan effects in UM-HET3 mice treated with fisetin and SG1002   (2024)

Miller RA, Strong R, Korstanje R, Harrison DE, Rosenthal NA


Studied compounds:


fisetin: A senolytic compound that may play an important role in mediating the effects of senescent cells on the pathophysiology of aging. [Wikipedia article]

SG1002: Slowly releases hydrogen sulfide which has numerous beneficial biological effects, including lifespan extension in C. elegans.