Studies involving Diversity Outbred (J:DO) population      

Filter by:
Data set Procedure What's in this data set Panel Sex Age (weeks) Year
Attie2 biomarker quantification
with high-fat high-sucrose diet
Bile acids in feces. DO population both 4-26wks 2018
Attie2 body weight
with high-fat high-sucrose diet
Weekly. DO population both 4-26wks 2018
Attie2 colony observation
with high-fat high-sucrose diet
Number of days on high-fat high-sucrose diet. DO population both 4-26wks 2018
Attie2 DXA
with high-fat high-sucrose diet
Bone mineral density. Isolated tibia. DO population both 4-26wks 2018
Attie2 glucose tolerance
with high-fat high-sucrose diet
Area under curve. DO population both 4-26wks 2018
Attie2 hormone quantification
with high-fat high-sucrose diet
Plasma insulin, adiponectin, leptin. Ex vivo insulin secretion. DO population both 4-26wks 2018
Attie2 intake monitoring
with high-fat high-sucrose diet
Food intake. Weekly. DO population both 4-26wks 2018
Attie2 lipid profile
with high-fat high-sucrose diet
Triglyceride. DO population both 4-26wks 2018
Attie2 metabolic panel
with high-fat high-sucrose diet
Glucose, HOMA-IR, HOMA-B. DO population both 4-26wks 2018
Attie2 microscopy
with high-fat high-sucrose diet
Number of islets harvested. DO population both 4-26wks 2018
Attie2 organ weights
with high-fat high-sucrose diet
Heart, liver, gonadal fat pads. DO population both 4-26wks 2018
CGDpheno4 glucose tolerance
with high-fat diet
High-fat diet vs. control. 0 to 120 min after 20% glucose i.p. 18h fast. DO population both 8,19wks 2015
CGDpheno4 lipid profile
with high-fat diet
Cholesterol, HDL, triglycerides, fatty acids. High-fat diet vs. control. Two age cohorts. 4h fast, plasma. DO population both 8,19wks 2015
CGDpheno4 metabolic panel
with high-fat diet
Clinical blood chemistry (plasma). High-fat diet vs. control. Some parameters at two age timepoints. 4h fast or no fast. DO population both 8,19wks 2015
CGDpheno5 complete blood count
with high-fat diet
Hematology. High-fat diet vs. control. Two age cohorts. DO population both 10,22wks 2015
CGDpheno6 body weight
with high-fat diet
Body weight and growth curve from age 3wks to 22wks weighed weekly. High-fat diet vs. control. DO population both 3-32wks 2015
CGDpheno6 organ weights
with high-fat diet
Heart, kidney, spleen weights. High-fat diet vs. control. DO population both 3-32wks 2015
CGDpheno7 body size and weight
with high-fat diet
Body weight and length. High-fat diet vs. control. Two age cohorts. DO population both 11-22wks 2015
CGDpheno7 DXA
with high-fat diet
Body mass, fat mass, lean mass, bone mineral density and content, bone area. High-fat diet vs. control. Two age cohorts. DO population both 11-22wks 2015
CGDpheno7 ECG
with high-fat diet
Wave amplitudes and intervals. Conscious. High-fat diet vs. control. Two age cohorts. DO population both 11-22wks 2015
CGDpheno7 urinalysis
with high-fat diet
Glucose, creatinine, albumin. High-fat diet vs. control. Two age cohorts. DO population both 11-22wks 2015
Chesler4 body weight Body weight DO population w/par   (9) both 12-16wks 2013
Chesler4 light-dark box Anxiety, avoidance behavior. 20 min test. DO population w/par   (9) both 12-16wks 2013
Chesler4 nociception assay Hot plate. DO population w/par   (9) both 12-16wks 2013
Chesler4 open field test Locomotor activity, exploratory, anxiety-related behavior. 20 min test. DO population w/par   (9) both 12-16wks 2013
Chesler4 tail suspension test Frequency climbing, time immobile, latency immobile. 5 min test. DO population w/par   (9) both 12-16wks 2013
Chesler4 visual cliff Anxiety, avoidance behavior. 20 min test. DO population w/par   (9) both 12-16wks 2013
Dickson2 hole board test
with cocaine
Exploratory behavior. 10 min test. DO population both 12-16wks 2015
Dickson2 monitoring system
with cocaine
Novelty preference test (preference for novel side vs. familiar side). 10 min test. DO population both 12-16wks 2015
Dickson2 open field test
with cocaine
Locomotor activity and exploratory behavior. 20 min test. DO population both 12-16wks 2015
Dickson2 operant conditioning chamber
with cocaine
Intravenous self-administration of cocaine via activation of levers. DO population both 12-16wks 2015
French1 chromosome instability assessment
with benzene
Percentages of erythrocytes and reticulocytes that are micronucleated before and after exposure. DO population m 5-8wks 2015
Gatti2 study archive Whole blood neutrophil count and white cell count. DO population both 10-12wks 2014
Hallgrimsson1 body weight Body weight DO population both 8-60 wks 2020
Hallgrimsson1 bone dimensions 3D, craniofacial landmark coordinates based on centroid. DO population both 8-60 wks 2020
Project1133 acoustic startle test
with various diets 3
Acoustic startle test DO population f 2022
Project1133 DXA
with various diets 3
Dxa DO population f 2022
Project1133 echocardiography
with various diets 3
Echocardiography DO population f 2022
Project1133 rotarod
with various diets 3
Rotarod DO population f 2022
Project1133 running wheel monitoring
with various diets 3
Running wheel monitoring DO population f 2022
Recla1 study archive Hot plate nociception. DO population both 13-17wks 2013
Recla2 nociception assay Formalin injection. DO population both 13-17wks 2019
Shorter2 body weight
with various diets
Diets vs controls. DO population both 12-15wks, 24-25wks 2018
Shorter2 bone dimensions
with various diets
Femur length. Diets vs controls. DO population both 12-15wks, 24-25wks 2018
Shorter2 colony observation
with various diets
Diets vs controls. DO population both 12-15wks, 24-25wks 2018
Shorter2 organ weights
with various diets
Heart weight, raw, adjusted to body weight, adjusted to femur length. Diets vs controls. DO population both 12-15wks, 24-25wks 2018
Shorter8 body weight Body weight DO population m 12-15wks 2020
Shorter8 histopathology Male reproductive histopathology. Percent normal, abnormal sperm. DO population m 12-15wks 2020
Shorter8 microscopy Sperm motility DO population m 12-15wks 2020
Shorter8 organ weights Male reproductive organ weights. Testes, seminal vesicles, epididymis + vas deferens. DO population m 12-15wks 2020
Shorter8 sperm count Sperm count. Hemocytometer. DO population m 12-15wks 2020
Svenson7 body size and weight
with high-fat high-sucrose diet
Body length at 12 and 21 wks of age. DO population both 3-30 wks 2020
Svenson7 body weight
with high-fat high-sucrose diet
Body weight from 3-30 wks of age. Principal components. DO population both 3-30 wks 2020
Svenson7 complete blood count
with high-fat high-sucrose diet
Hematology at 10 and 22 wks of age. DO population both 3-30 wks 2020
Svenson7 DXA
with high-fat high-sucrose diet
Body mass, lean mass, fat mass, bone mineral density at 12 and 21 wks of age. DO population both 3-30 wks 2020
Svenson7 ECG
with high-fat high-sucrose diet
Heart rate and wave intervals at 13 wks. Conscious. DO population both 3-30 wks 2020
Svenson7 glucose tolerance
with high-fat high-sucrose diet
0-180 min after 20% glucose i.p. at 23-24 wks of age. 15h fast. DO population both 3-30 wks 2020
Svenson7 lipid profile
with high-fat high-sucrose diet
Cholesterol, fatty acids, triglyceride at 8 and 19 wks of age. 4h fast. DO population both 3-30 wks 2020
Svenson7 metabolic panel
with high-fat high-sucrose diet
Clinical chemistry at 8 and 19 wks of age. 4h fast. Clinical chemistry at 17 wks of age. No fast. DO population both 3-30 wks 2020
Svenson7 MRI
with high-fat high-sucrose diet
Lean and fat tissue mass, water mass at 16 wks of age. DO population both 3-30 wks 2020
Svenson7 organ weights
with high-fat high-sucrose diet
Heart, kidney, spleen at 26-30 wks. DO population both 3-30 wks 2020
Svenson7 urinalysis
with high-fat high-sucrose diet
Glucose, creatinine, microalbumin, albumin-creatinine ratio at 11 and 20 wks of age. DO population both 3-30 wks 2020
Xenakis2 body weight
with arsenic
Baseline, then after iAs exposure for 26 wks DO population m 4-34 wks 2022
Xenakis2 hormone quantification
with arsenic
Blood insulin following 6 h fast, and after intraperitoneal glucose injection; at baseline and after iAs exposure DO population m 4-34 wks 2022
Xenakis2 intake monitoring
with arsenic
Food and water consumption, at baseline then at 1 to 4 wk intervals after iAs exposure DO population m 4-34 wks 2022
Xenakis2 metabolic panel
with arsenic
Blood glucose following 6 h fast, and after intraperitoneal glucose injection; at baseline and after iAs exposure DO population m 4-34 wks 2022
Xenakis2 metabolite quantification
with arsenic
iAs quantification in urine and liver, at 24 and 26 wks after iAs exposure. IAs speciation evaluated specifically monomethyl-arsenic acid (MMA) and dimethyl-arsenic acid (DMA) DO population m 4-34 wks 2022
Xenakis2 MRI
with arsenic
Fat and lean tissue mass at baseline, and 12 and 24 wks after iAs exposure DO population m 4-34 wks 2022
Xenakis2 urinalysis
with arsenic
Urine volume at baseline, and 12 and 24 wks after iAs exposure DO population m 4-34 wks 2022