MPD: Project measures / variables set: GMC20 IgG2b

Project measures / variables set: GMC20 IgG2b

ID, description, units	MPD:56910 IgG2b immunoglobulin G2b (plasma IgG2b) [µg/mL]
Measures	• age 16-17wks • 20-21wks
Data set, strains	GMC20 inbred w/CC8 8 strains sex: both
Procedure	immunoglobulin quantification
Comparison	multiple cohorts measured at two age timepoints
Ontology mappings	VT:0008497 blood immunoglobulin G2b amount VT:0002144 B cell development trait MA:0002501 plasma MP:0020177 abnormal IgG2b level

Values Means Δ Means Z-scores

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GMC20 - immunoglobulin G2b (plasma IgG2b)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	1	407066.9385	407066.9385	70.6727	< 0.0001
sex	1	592.4528	592.4528	0.1029	0.7498
strain	3	473308.4069	157769.469	27.3911	< 0.0001
age:sex	1	3702.9454	3702.9454	0.6429	0.4265
age:strain	3	101295.0021	33765.0007	5.8621	0.0016
sex:strain	3	59042.3351	19680.7784	3.4169	0.0242
age:sex:strain	3	10580.2088	3526.7363	0.6123	0.6102
Residuals	50	287994.3255	5759.8865

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
GMC20	56910	immunoglobulin quantification	(none)	immunoglobulin G2b (plasma IgG2b) [µg/mL] at age 16-17wks IgG2b_17	inbred w/CC8	5	both	16-17wks
GMC20	56911	immunoglobulin quantification	(none)	immunoglobulin G2b (plasma IgG2b) [µg/mL] at age 20-21wks IgG2b_21	inbred w/CC8	8	both	20-21wks