MPD: Project measures / variables set: Jentsch2 discrimination

Project measures / variables set: Jentsch2 discrimination_FR2

ID, description, units	MPD:49717 discrimination_FR2 Fixed ratio 2 - discrimination index between active and inactive levers [%] cocaine study
Measures	• day 1 • day 2 • day 4
Data set, strains	Jentsch2 BXD 4 strains sex: both age: 8-17wks
Procedure	operant conditioning chamber
Comparison	repeated measures, set of trials, same cohort
Ontology mappings	VT:0002063 learning/memory/conditioning trait VT:0010473 impulsivity behavior trait VT:0010531 operant conditioning behavior trait VT:0010718 response to cocaine trait MP:0002803 abnormal operant conditioning behavior MP:0010698 abnormal impulsive behavior control MP:0020158 abnormal behavioral response to cocaine MP:0001988 cocaine preference

Values Means Δ Means Z-scores

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Jentsch2 - Fixed ratio 2 - discrimination index between active and inactive levers

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	9.6833	9.6833	0.1398	0.7126
between strain	1	30.8673	30.8673	0.4456	0.5125
between sex:strain	1	15.1305	15.1305	0.2184	0.6456
between Residuals	19	1316.1574	69.2714
within group	2	61.25	30.625	1.0102	0.3737
within group:sex	2	4.9738	2.4869	0.082	0.9214
within group:strain	2	141.185	70.5925	2.3286	0.1112
within group:sex:strain	2	21.8413	10.9207	0.3602	0.6999
within Residuals	38	1152.0107	30.3161

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Jentsch2	49717	operant conditioning chamber	cocaine	Fixed ratio 2 - discrimination index between active and inactive levers [%] day 1 discrimination1_FR2	BXD	4	both	8-17wks
Jentsch2	49718	operant conditioning chamber	cocaine	Fixed ratio 2 - discrimination index between active and inactive levers [%] day 2 discrimination2_FR2	BXD	4	both	8-17wks
Jentsch2	49719	operant conditioning chamber	cocaine	Fixed ratio 2 - discrimination index between active and inactive levers [%] day 4 discrimination4_FR2	BXD	4	both	8-17wks