Project measure / variable:   Jentsch2   discrimination4_FR2

ID, description, units MPD:49719   discrimination4_FR2   Fixed ratio 2 - discrimination index between active and inactive levers   [%]  day 4  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 2 - discrimination index between active and inactive levers day 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means91.1   % 90.5   %
Median of the strain means91.1   % 90.0   %
SD of the strain means± 2.62 ± 1.91
Coefficient of variation (CV)0.0287 0.0211
Min–max range of strain means89.2   –   92.9   % 88.9   –   93.3   %
Mean sample size per strain4.5   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0006 0.0006 0.0 0.9977
strain 1 76.1836 76.1836 1.1275 0.3016
sex:strain 1 0.5905 0.5905 0.0087 0.9265
Residuals 19 1283.8161 67.5693


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 90.1 9.86   7 3.73 0.11 75.0, 100.0 -0.24
BXD38/TyJ f 92.9 4.21   7 1.59 0.0453 88.2, 98.4 0.71
BXD38/TyJ m 93.3 8.61   10 2.72 0.0923 78.8, 100.0 1.44
BXD42/TyJ m 89.9 6.98   11 2.1 0.0776 75.6, 100.0 -0.34
BXD68/RwwJ f 89.2 15.2   2   10.8 0.171 78.5, 100.0 -0.71
BXD68/RwwJ m 88.9 9.62   4 4.81 0.108 78.5, 100.0 -0.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 92.8843 3.1069 99.3871 86.3815
BXD38/TyJ m 93.325 2.5994 98.7656 87.8844
BXD68/RwwJ f 89.225 5.8125 101.3906 77.0594
BXD68/RwwJ m 88.9 4.11 97.5024 80.2976


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 93.1046 2.0254 97.3439 88.8653
BXD68/RwwJ both 89.0625 3.5594 96.5124 81.6126




GWAS analysis not available: SNP data is not available for enough strains (at least 4)