MPD: Project measures / variables set: Harrill1 ALT

Project measures / variables set: Harrill1 ALT

ID, description, units	MPD:39521 ALT alanine transaminase (serum ALT) [IU/L] isoniazid study
Measures	• control • isoniazid
Data set, strains	Harrill1 inbred 34 strains sex: f age: 8-10wks
Procedure	metabolic panel
Comparison	control group vs. treated group
Ontology mappings	VT:0010487 response to xenobiotic stimulus trait VT:0001573 blood alanine transaminase amount MA:0002502 serum MP:0008872 abnormal physiological response to xenobiotic MP:0001573 abnormal circulating alanine transaminase level

Values Means Δ Means Z-scores

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Harrill1 - alanine transaminase (serum ALT)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	3566.9102	3566.9102	3.0205	0.084
strain	31	43675.2662	1408.8796	1.1931	0.2368
group:strain	31	31422.0531	1013.6146	0.8583	0.6838
Residuals	177	209017.4508	1180.8896

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Harrill1	39521	metabolic panel	isoniazid	alanine transaminase (serum ALT) [IU/L] control ALT_ctrl	inbred	34	f	8-10wks
Harrill1	39522	metabolic panel	isoniazid	alanine transaminase (serum ALT) [IU/L] isoniazid ALT_trt	inbred	33	f	8-10wks