MPD: Project measures / variables set: Wiltshire2 OFT

Project measures / variables set: Wiltshire2 OFT_dist

ID, description, units	MPD:38005 OFT_dist OFT distance traveled, 10 min test [cm] fluoxetine study
Measures	• control • fluoxetine
Data set, strains	Wiltshire2 inbred 30 strains sex: m age: 10-11wks
Procedure	open field test
Comparison	control group vs. treated group
Ontology mappings	VT:0001392 locomotor behavior trait VT:0010471 exploratory behavior trait VT:0010487 response to xenobiotic stimulus trait VT:0010716 anxiety-related behavior trait MP:0001362 abnormal anxiety-related response MP:0001392 abnormal locomotor behavior MP:0013189 abnormal exploration in a new environment MP:0009745 abnormal behavioral response to xenobiotic

Values Means Δ Means Z-scores

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Wiltshire2 - OFT distance traveled, 10 min test

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	4022727.6437	4022727.6437	11.9137	0.0006
strain	29	298999670.0467	10310333.4499	30.535	< 0.0001
group:strain	29	29066208.3219	1002283.0456	2.9683	< 0.0001
Residuals	606	204619971.2054	337656.7182

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Wiltshire2	38005	open field test	fluoxetine	OFT distance traveled, 10 min test [cm] control OFT_dist_cont	inbred	30	m	10-11wks
Wiltshire2	38006	open field test	fluoxetine	OFT distance traveled, 10 min test [cm] fluoxetine OFT_dist_fluox	inbred	30	m	10-11wks