MPD: Project measures / variables set: Crabbe3 FS_10rpm

Project measures / variables set: Crabbe3 FS_10rpm_EtOH

ID, description, units	MPD:15820 FS_10rpm_EtOH latency to fall, fixed speed 10 rpm rotarod [s] ethanol study
Measures	• dose (g/kg): 1 • 2 • 3
Data set, strains	Crabbe3 inbred 9 strains sex: both age: 9-17wks
Procedure	rotarod
Comparison	multiple dosage cohorts but no control group
Ontology mappings	VT:0001516 motor coordination/balance trait VT:0010489 response to alcohol trait MP:0001516 abnormal motor coordination/balance MP:0020157 abnormal behavioral response to alcohol

Values Means Δ Means Z-scores

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Crabbe3 - latency to fall, fixed speed 10 rpm rotarod

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
dose	2	20762.8739	10381.4369	5.1098	0.0099
sex	1	479.3226	479.3226	0.2359	0.6295
strain	3	16781.2215	5593.7405	2.7533	0.0532
dose:sex	2	7882.3546	3941.1773	1.9399	0.1553
dose:strain	6	3762.3239	627.054	0.3086	0.9293
sex:strain	3	4570.9701	1523.6567	0.75	0.528
dose:sex:strain	6	9568.7034	1594.7839	0.785	0.5862
Residuals	46	93456.9958	2031.6738

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Crabbe3	15820	rotarod	ethanol	latency to fall, fixed speed 10 rpm rotarod [s] dose: 1 g/kg i.p. FS_10rpm_EtOH_1	inbred	8	both	9-17wks
Crabbe3	15821	rotarod	ethanol	latency to fall, fixed speed 10 rpm rotarod [s] dose: 2 g/kg i.p. FS_10rpm_EtOH_2	inbred	8	both	9-17wks
Crabbe3	15822	rotarod	ethanol	latency to fall, fixed speed 10 rpm rotarod [s] dose: 3 g/kg i.p. FS_10rpm_EtOH_3	inbred	9	both	9-17wks