Project measure / variable:   Crabbe3   FS_10rpm_EtOH_1

ID, description, units MPD:15820   FS_10rpm_EtOH_1   latency to fall, fixed speed 10 rpm rotarod   [s]  dose: 1 g/kg i.p.  
ethanol study
Data set, strains Crabbe3   inbred   8 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, fixed speed 10 rpm rotarod dose: 1 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means96.0   s 92.5   s
Median of the strain means98.6   s 94.8   s
SD of the strain means± 15.4 ± 31.5
Coefficient of variation (CV)0.161 0.340
Min–max range of strain means72.6   –   116   s 49.0   –   140   s
Mean sample size per strain3.1   mice 2.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 325.3797 325.3797 0.1091 0.7444
strain 4 9346.8795 2336.7199 0.7835 0.5486
sex:strain 4 8739.4759 2184.869 0.7326 0.5799
Residuals 21 62629.8733 2982.3749


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 105.0 71.7   3 41.4 0.683 37.0, 180.0 0.58
B6D2F1/J f 85.5 50.1   3 28.9 0.586 37.0, 137.0 -0.68
B6D2F1/J m 49.0 21.1   3 12.2 0.432 29.4, 71.4 -1.38
BALB/cByJ f 109.0 47.4   3 27.4 0.434 73.6, 163.0 0.84
BALB/cByJ m 116.0 49.1   3 28.4 0.425 77.6, 171.0 0.74
BTBR T+ Itpr3tf/J f 116.0 56.4   3 32.6 0.485 72.7, 180.0 1.3
BTBR T+ Itpr3tf/J m 94.8 0.0   1   0.0 0.0 94.8, 94.8 0.07
C3H/HeJ f 72.6 27.0   4 13.5 0.371 47.8, 111.0 -1.52
C3H/HeJ m 107.0 103.0   2   72.9 0.964 34.1, 180.0 0.46
C57BL/6J f 98.6 70.5   3 40.7 0.715 57.4, 180.0 0.17
C57BL/6J m 76.5 24.2   4 12.1 0.317 41.9, 98.3 -0.51
DBA/2J m 64.5 4.95   2   3.5 0.0767 61.0, 68.0 -0.89
FVB/NJ f 85.4 82.0   3 47.3 0.96 37.4, 180.0 -0.69
FVB/NJ m 140.0 68.7   3 39.7 0.49 61.0, 180.0 1.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J f 85.4667 31.5297 151.0364 19.897
B6D2F1/J m 48.9667 31.5297 114.5364 0.0
BALB/cByJ f 109.1667 31.5297 174.7364 43.597
BALB/cByJ m 115.5 31.5297 181.0697 49.9303
C3H/HeJ f 72.625 27.3056 129.41 15.84
C3H/HeJ m 107.05 38.6159 187.3562 26.7438
C57BL/6J f 98.6 31.5297 164.1697 33.0303
C57BL/6J m 76.475 27.3056 133.26 19.69
FVB/NJ f 85.3667 31.5297 150.9364 19.797
FVB/NJ m 140.3333 31.5297 205.903 74.7636


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J both 67.2167 22.2949 113.5814 20.8519
BALB/cByJ both 112.3333 22.2949 158.6981 65.9686
C3H/HeJ both 89.8375 23.6473 139.0148 40.6602
C57BL/6J both 87.5375 20.855 130.9078 44.1672
FVB/NJ both 112.85 22.2949 159.2148 66.4852




  GWAS USING LINEAR MIXED MODELS