MPD: Project measures / variables set: Crabbe1 grid

Project measures / variables set: Crabbe1 grid_ataxia

ID, description, units	MPD:15407 grid_ataxia grid habituation, missteps per cm [n/cm] ethanol study
Measures	• dose (g/kg): control • 1.5 • 2.0 • 2.5
Data set, strains	Crabbe1 inbred 8 strains sex: both age: 8-16wks
Procedure	grid test
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0001516 motor coordination/balance trait VT:0010489 response to alcohol trait MP:0001516 abnormal motor coordination/balance MP:0020157 abnormal behavioral response to alcohol

Values Means Δ Means Z-scores

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Crabbe1 - grid habituation, missteps per cm

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
dose	3	3.1112	1.0371	74.8106	< 0.0001
sex	1	0.0236	0.0236	1.7053	0.1935
strain	3	0.0503	0.0168	1.2093	0.3083
dose:sex	3	0.0295	0.0098	0.7098	0.5475
dose:strain	9	0.2533	0.0281	2.0299	0.0395
sex:strain	3	0.0066	0.0022	0.1588	0.9239
dose:sex:strain	9	0.1229	0.0137	0.985	0.4547
Residuals	154	2.1348	0.0139

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Crabbe1	15407	grid test	ethanol	grid habituation, missteps per cm [n/cm] control grid_ataxia	inbred	8	both	8-16wks
Crabbe1	15418	grid test	ethanol	grid habituation, missteps per cm [n/cm] dose 1.5 g/kg i.p. grid_ataxia_doseD	inbred	8	both	8-16wks
Crabbe1	15420	grid test	ethanol	grid habituation, missteps per cm [n/cm] dose 2.0 g/kg i.p. grid_ataxia_doseE	inbred	8	both	8-16wks
Crabbe1	15422	grid test	ethanol	grid habituation, missteps per cm [n/cm] dose 2.5 g/kg i.p. grid_ataxia_doseF	inbred	8	both	8-16wks