MPD: Project measures / variables set: Crabbe1 bal12

Project measures / variables set: Crabbe1 bal12

ID, description, units	MPD:15403 bal12 missteps crossing 12.7mm wide balance beam [n] ethanol study
Measures	• dose (g/kg) control • 1.0 • 1.2 • 1.4
Data set, strains	Crabbe1 inbred 8 strains sex: both age: 8-16wks
Procedure	balance beam
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0001516 motor coordination/balance trait VT:0010489 response to alcohol trait MP:0001516 abnormal motor coordination/balance MP:0020157 abnormal behavioral response to alcohol

Values Means Δ Means Z-scores

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Crabbe1 - missteps crossing 12.7mm wide balance beam

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
dose	3	198.3039	66.1013	10.3711	< 0.0001
sex	1	4.5593	4.5593	0.7153	0.3989
strain	4	36.1577	9.0394	1.4183	0.2301
dose:sex	3	5.0078	1.6693	0.2619	0.8528
dose:strain	12	86.3711	7.1976	1.1293	0.3397
sex:strain	4	20.5928	5.1482	0.8077	0.5218
dose:sex:strain	12	86.8548	7.2379	1.1356	0.3347
Residuals	166	1058.0144	6.3736

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Crabbe1	15403	balance beam	ethanol	missteps crossing 12.7mm wide balance beam [n] control bal12	inbred	7	both	8-16wks
Crabbe1	15408	balance beam	ethanol	missteps crossing 12.7mm wide balance beam [n] dose 1.0 g/kg i.p. bal12_doseA	inbred	8	both	8-16wks
Crabbe1	15409	balance beam	ethanol	missteps crossing 12.7mm wide balance beam [n] dose 1.2 g/kg i.p. bal12_doseB	inbred	8	both	8-16wks
Crabbe1	15410	balance beam	ethanol	missteps crossing 12.7mm wide balance beam [n] dose 1.4 g/kg i.p. bal12_doseC	inbred	8	both	8-16wks